|Terms & Properties|
Concept Unique Identifier (CUI): C1704436
NCI Thesaurus Code: C84496 (see NCI Thesaurus info)
Semantic Type: Disease or Syndrome
NCIt Definition: A disorder of the arteries supplying the upper and lower extremity and the visceral organs. This includes the mesenteric arteries, the renal arteries and the aorta and excludes cerebrovascular arterial disease. Patients experience cramping and pain usually in the calves and thighs while walking. The symptoms subside with rest.
Peripheral arterial disease (PAD) happens when there is a narrowing of the blood vessels outside of your heart. The cause of PAD is atherosclerosis. This happens when plaque builds up on the walls of the arteries that supply blood to the arms and legs. Plaque is a substance made up of fat and cholesterol. It causes the arteries to narrow or become blocked. This can reduce or stop blood flow, usually to the legs. If severe enough, blocked blood flow can cause tissue death and can sometimes lead to amputation of the foot or leg.
The main risk factor for PAD is smoking. Other risk factors include older age and diseases like diabetes, high blood cholesterol, high blood pressure, heart disease, and stroke.
Many people who have PAD don't have any symptoms. If you have symptoms, they may include
Doctors diagnose PAD with a physical exam and heart and imaging tests. Treatments include lifestyle changes, medicines, and sometimes surgery. Lifestyle changes include dietary changes, exercise, and efforts to lower high cholesterol levels and high blood pressure.
NIH: National Heart, Lung, and Blood Institute
MSH Definition: Lack of perfusion in the EXTREMITIES resulting from atherosclerosis. It is characterized by INTERMITTENT CLAUDICATION, and an ANKLE BRACHIAL INDEX of 0.9 or less.
Synonyms & Abbreviations: (see Synonym Details)
|Arterial Disease, Peripheral|
|Arterial Diseases, Peripheral|
|Artery Disease, Peripheral|
|Artery Diseases, Peripheral|
|Disease, Peripheral Arterial|
|Disease, Peripheral Artery|
|Diseases, Peripheral Arterial|
|Diseases, Peripheral Artery|
|Peripheral Arterial Disease [Disease/Finding]|
|Peripheral Arterial Diseases|
|Peripheral arterial disease|
|Peripheral Arterial Disorder|
|Peripheral Artery Diseases|
|Peripheral artery disease|
External Source Codes:
|NCI Thesaurus Code||C84496 (see NCI Thesaurus info)|
|AN||coordinate IM with specific peripheral artery IM if pertinent||MSH|
|AQL||BL CF CI CL CN CO DG DH DI DT EC EH EM EN EP ET GE HI IM ME MI MO NU PA PC PP PS PX RH RT SU TH UR VE VI||MSH|
|HN||2011; for PERIPHERAL ARTERIAL DISEASES use PERIPHERAL VASCULAR DISEASES 2007-2010||MSH|
|MESH_DEFINITION||Lack of perfusion in the EXTREMITIES resulting from atherosclerosis. It is characterized by INTERMITTENT CLAUDICATION, and an ANKLE BRACHIAL INDEX of 0.9 or less.||NDFRT|
|MESH_NAME||Peripheral Arterial Disease||NDFRT|
|MP_OTHER_LANGUAGE_URL||Chinese - Simplified https://www.nlm.nih.gov/medlineplus/languages/peripheralarterialdisease.html#Chinese - Simplified||MEDLINEPLUS|
|MP_OTHER_LANGUAGE_URL||Chinese - Traditional https://www.nlm.nih.gov/medlineplus/languages/peripheralarterialdisease.html#Chinese - Traditional||MEDLINEPLUS|
|MP_PRIMARY_INSTITUTE_URL||National Heart, Lung, and Blood Institute http://www.nhlbi.nih.gov/||MEDLINEPLUS|
|PM||2011; for PERIPHERAL ARTERIAL DISEASES see PERIPHERAL VASCULAR DISEASES 2007-2010||MSH|
Additional Concept Data: (none)