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Phenolphthalein (CUI C0600489) Suggest changes to this concept
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Terms & Properties

Concept Unique Identifier (CUI): C0600489

NCI Thesaurus Code: C29359  (see NCI Thesaurus info)

Semantic Type: Pharmacologic Substance

Semantic Type: Indicator, Reagent, or Diagnostic Aid

Semantic Type: Organic Chemical

NCIt Definition: An organic compound used as a laboratory reagent and pH indicator. Phenolphthalein exerts laxative effects by stimulating the intestinal mucosa and constricting smooth muscles. However, phenolphthalein is no longer used as a laxative due to the suspected carcinogenicity of this compound.

MSH Definition: An acid-base indicator which is colorless in acid solution, but turns pink to red as the solution becomes alkaline. It is used medicinally as a cathartic.

Synonyms & Abbreviations: (see Synonym Details)
1(3H)-Isobenzofuranone, 3,3-bis(4-hydroxyphenyl)-
3,3-Bis(4-hydroxyphenyl)-1(3H)-isobenzofuranone
3,3-Bis(p-hydroxyphenyl)phthalide
Phenolphthalein (product)
Phenolphthalein (substance)
Phenolphthalein [Chemical/Ingredient]
PHENOLPHTHALEIN,WHITE
PHENOLPHTHALEIN
PHENPOLPHTHALEIN

External Source Codes: 
NCI Thesaurus Code C29359 (see NCI Thesaurus info)
CAS Registry Number 77-09-8 (see NLM ChemIDplus info)
FDA UNII Code 6QK969R2IF
NSC Code 10464 (see NCI DTP info)

Other Properties: Property Definitions
Name Value Source
ACTIVE 1 SNOMEDCT_US
AN PHENOLPHTHALEINS is also available MSH
AQL AD AE AG AI AN BL CF CH CL CS CT EC HI IM IP ME PD PK PO RE SD ST TO TU UR MSH
CASE_SIGNIFICANCE_ID 900000000000448009 SNOMEDCT_US
CHARACTERISTIC_TYPE_ID 900000000000011006 SNOMEDCT_US
CHEBI_ID CHEBI:34914 NCI
Chemical_Formula C20H14O4 NCI
Contributing_Source FDA NCI
CTV3ID X796i SNOMEDCT_US
CTV3ID XUYi5 SNOMEDCT_US
DC 1 MSH
DEFINITION_STATUS_ID 900000000000074008 SNOMEDCT_US
DX 19990101 MSH
EC analogs & derivatives:Phenolphthaleins MSH
EFFECTIVE_TIME 20020131 SNOMEDCT_US
EFFECTIVE_TIME 20030731 SNOMEDCT_US
FDA_UNII_CODE 6QK969R2IF NDFRT
HN 99; use PHENOLPHTHALEIN (NM) 1983-98 MSH
LEVEL Ingredient NDFRT
MDA 19980610 MSH
MESH_DEFINITION An acid-base indicator which is colorless in acid solution, but turns pink to red as the solution becomes alkaline. It is used medicinally as a cathartic. NDFRT
MESH_DUI D020113 NDFRT
MESH_NAME Phenolphthalein NDFRT
MESH_UI M0029852 NDFRT
MMR 20160701 MSH
MN D02.455.426.559.389.657.625.555 MSH
MODIFIER_ID 900000000000451002 SNOMEDCT_US
NDFRT_KIND DRUG_KIND NDFRT
NDFRT_KIND INGREDIENT_KIND NDFRT
NUI N0000006578 NDFRT
NUI N0000147222 NDFRT
NUI N0000148180 NDFRT
NUI N0000148413 NDFRT
PA D007202 MSH
PM 99; PHENOLPHTHALEIN was indexed under PHENOLPHTHALEINS 1983-98 MSH
RN 6QK969R2IF MSH
RR 77-09-8 (Phenolphthalein) MSH
RXAUI 1011571 RXNORM
RXAUI 1474128 RXNORM
RXAUI 2072932 RXNORM
RXAUI 2072935 RXNORM
RXAUI 3090990 RXNORM
RXAUI 3213655 RXNORM
RXAUI 3213656 RXNORM
RXAUI 3213669 RXNORM
RXAUI 3213670 RXNORM
RXAUI 3213695 RXNORM
RXAUI 3213696 RXNORM
RXAUI 3219785 RXNORM
RXAUI 3219786 RXNORM
RXAUI 7749246 RXNORM
RXCUI 155122 RXNORM
SPL_SET_ID 2f3d404d-d01f-0466-e054-00144ff8d46c MTHSPL
SUBSET_MEMBER 900000000000497000~MAPTARGET~X796i SNOMEDCT_US
SUBSET_MEMBER 900000000000497000~MAPTARGET~XUYi5 SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
TERMUI T059871 MSH
TH BAN (19XX) MSH
TH FDA SRS (2014) MSH
TH INN (19XX) MSH
TH NLM (1999) MSH
TH USP (19XX) MSH
TYPE_ID 900000000000003001 SNOMEDCT_US
TYPE_ID 900000000000013009 SNOMEDCT_US
VANDF_RECORD 50.416^1534^Active/Master NDFRT
VANDF_RECORD 50.416^2980^Active/Master NDFRT
VANDF_RECORD 50.416^3592^Active/Master NDFRT
VANDF_RECORD 50.6^2088^Active/Master NDFRT
VUID 4018930 NDFRT
VUID 4020338 NDFRT
VUID 4020931 NDFRT

Additional Concept Data:  (none)

URL to Bookmark: https://ncim-stage.nci.nih.gov/ncimbrowser/ConceptReport.jsp?dictionary=NCI Metathesaurus&code=C0600489

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