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Dementia (CUI C0497327) Suggest changes to this concept
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Terms & Properties

Concept Unique Identifier (CUI): C0497327

NCI Thesaurus Code: C4786  (see NCI Thesaurus info)

Semantic Type: Mental or Behavioral Dysfunction

NCIt Definition: Loss of intellectual abilities interfering with an individual's social and occupational functions. Causes include Alzheimer's disease, brain injuries, brain tumors, and vascular disorders.

RADLEX Definition: An acquired organic mental disorder with loss of intellectual abilities of sufficient severity to interfere with social or occupational functioning. The dysfunction is multifaceted and involves memory, behavior, personality, judgment, attention, spatial relations, language, abstract thought, and other executive functions. The intellectual decline is usually progressive, and initially spares the level of consciousness. [MeSH]

HPO Definition: A loss of global cognitive ability of sufficient amount to interfere with normal social or occupational function. Dementia represents a loss of previously present cognitive abilities, generally in adults, and can affect memory, thinking, language, judgment, and behavior. [HPO:probinson]

MEDLINEPLUS Definition: 

Dementia is the name for a group of symptoms caused by disorders that affect the brain. It is not a specific disease. People with dementia may not be able to think well enough to do normal activities, such as getting dressed or eating. They may lose their ability to solve problems or control their emotions. Their personalities may change. They may become agitated or see things that are not there.

Memory loss is a common symptom of dementia. However, memory loss by itself does not mean you have dementia. People with dementia have serious problems with two or more brain functions, such as memory and language. Although dementia is common in very elderly people, it is not part of normal aging.

Many different diseases can cause dementia, including Alzheimer's disease and stroke. Drugs are available to treat some of these diseases. While these drugs cannot cure dementia or repair brain damage, they may improve symptoms or slow down the disease.

NIH: National Institute of Neurological Disorders and Stroke

NCI-GLOSS Definition: A condition in which a person loses the ability to think, remember, learn, make decisions, and solve problems. Symptoms may also include personality changes and emotional problems. There are many causes of dementia, including Alzheimer disease, brain cancer, and brain injury. Dementia usually gets worse over time.

MSH Definition: An acquired organic mental disorder with loss of intellectual abilities of sufficient severity to interfere with social or occupational functioning. The dysfunction is multifaceted and involves memory, behavior, personality, judgment, attention, spatial relations, language, abstract thought, and other executive functions. The intellectual decline is usually progressive, and initially spares the level of consciousness.

Synonyms & Abbreviations: (see Synonym Details)
-- Dementia
Amentias
amentia
Dementia (disorder)
Dementia [Disease/Finding]
Dementia NOS
Dementia, progressive
Dementia, unspecified
Dementias
dementia
Demenz
Organic dementia
Progressive dementia
Unspecified dementia

External Source Codes: 
NCI Thesaurus Code C4786 (see NCI Thesaurus info)

Other Properties: Property Definitions
Name Value Source
ACTIVE 1 SNOMEDCT_US
AQL BL CF CI CL CO DG DH DI DT EC EH EN EP ET GE HI IM ME MI MO NU PA PC PP PS PX RH SU TH UR VI MSH
CASE_SIGNIFICANCE_ID 900000000000020002 SNOMEDCT_US
CHARACTERISTIC_TYPE_ID 900000000000011006 SNOMEDCT_US
Contributing_Source FDA NCI
CTV3ID X002w SNOMEDCT_US
DATE_CREATED 07/13/1999 MEDLINEPLUS
DC 1 MSH
DEFINITION_STATUS_ID 900000000000074008 SNOMEDCT_US
DX 19810101 MSH
EFFECTIVE_TIME 20020131 SNOMEDCT_US
EXCLUDES1 senility NOS (R41.81) ICD10CM
EXCLUDES2 mild memory disturbance due to known physiological condition (F06.8) ICD10CM
EXCLUDES2 senile dementia with delirium or acute confusional state (F05) ICD10CM
EXTERNALLY_DEFINED N LNC
FDA_Table Patient Code (Appendix B) NCI
FX D024801 MSH
HN 1981(1963) MSH
IAN DEFAULT ICD10
ICN Code first the associated neurological condition ICD9CM
INCLUSION_TERM Presenile: dementia NOS ICD10
INCLUSION_TERM Presenile: psychosis NOS ICD10
INCLUSION_TERM Primary degenerative dementia NOS ICD10
INCLUSION_TERM Senile: dementia: depressed or paranoid type ICD10
INCLUSION_TERM Senile: dementia: NOS ICD10
INCLUSION_TERM Senile: psychosis NOS ICD10
MDA 19800521 MSH
MESH_DEFINITION An acquired organic mental disorder with loss of intellectual abilities of sufficient severity to interfere with social or occupational functioning. The dysfunction is multifaceted and involves memory, behavior, personality, judgment, attention, spatial relations, language, abstract thought, and other executive functions. The intellectual decline is usually progressive, and initially spares the level of consciousness. NDFRT
MESH_DUI D003704 NDFRT
MESH_NAME Dementia NDFRT
MESH_UI M0005797 NDFRT
MMR 20150630 MSH
MN C10.228.140.380 MSH
MN F03.615.400 MSH
MODIFIER_ID 900000000000451002 SNOMEDCT_US
MODULE_ID 731000124108 SNOMEDCT_US
MODULE_NAME US National Library of Medicine maintained module SNOMEDCT_US
MP_HEALTH_TOPIC_URL https://www.nlm.nih.gov/medlineplus/dementia.html MEDLINEPLUS
MP_OTHER_LANGUAGE_URL Chinese - Simplified https://www.nlm.nih.gov/medlineplus/languages/dementia.html#Chinese - Simplified MEDLINEPLUS
MP_OTHER_LANGUAGE_URL Chinese - Traditional https://www.nlm.nih.gov/medlineplus/languages/dementia.html#Chinese - Traditional MEDLINEPLUS
MP_OTHER_LANGUAGE_URL French https://www.nlm.nih.gov/medlineplus/languages/dementia.html#French MEDLINEPLUS
MP_OTHER_LANGUAGE_URL Hindi https://www.nlm.nih.gov/medlineplus/languages/dementia.html#Hindi MEDLINEPLUS
MP_OTHER_LANGUAGE_URL Japanese https://www.nlm.nih.gov/medlineplus/languages/dementia.html#Japanese MEDLINEPLUS
MP_OTHER_LANGUAGE_URL Korean https://www.nlm.nih.gov/medlineplus/languages/dementia.html#Korean MEDLINEPLUS
MP_OTHER_LANGUAGE_URL Russian https://www.nlm.nih.gov/medlineplus/languages/dementia.html#Russian MEDLINEPLUS
MP_OTHER_LANGUAGE_URL Somali https://www.nlm.nih.gov/medlineplus/languages/dementia.html#Somali MEDLINEPLUS
MP_OTHER_LANGUAGE_URL Spanish https://www.nlm.nih.gov/medlineplus/spanish/dementia.html MEDLINEPLUS
MP_OTHER_LANGUAGE_URL Ukrainian https://www.nlm.nih.gov/medlineplus/languages/dementia.html#Ukrainian MEDLINEPLUS
MP_PRIMARY_INSTITUTE_URL National Institute on Aging http://www.nia.nih.gov/ MEDLINEPLUS
NDFRT_KIND DISEASE_KIND NDFRT
NUI N0000000914 NDFRT
ORDER_NO 04821 ICD10CM
ORDER_NO 04822 ICD10CM
PM 1981; see DEMENTIA, SENILE 1979-91; see PSYCHOSES, SENILE 1963-78; see PSYCHOSES, PRESENILE 1963-72; see PICK DISEASE OF BRAIN 1981-91; see PICK'S DISEASE OF BRAIN 1966-80; for DEMENTIA, PRESENILE see DEMENTIA 1967-97; for DEMENTIA, SENILE see DEMENTIA 1966-97 MSH
PRIMARY_PATH 10012267$10012268$10057167$10029205$Dementia$Dementia (excl Alzheimer's type)$Mental impairment disorders$Nervous system disorders MDR
PRIMARY_SOC 10029205 MDR
PT_IN_VERSION 10.0 MDR
PT_IN_VERSION 10.1 MDR
PT_IN_VERSION 11.0 MDR
PT_IN_VERSION 11.1 MDR
PT_IN_VERSION 12.0 MDR
PT_IN_VERSION 12.1 MDR
PT_IN_VERSION 13.0 MDR
PT_IN_VERSION 13.1 MDR
PT_IN_VERSION 14.0 MDR
PT_IN_VERSION 14.1 MDR
PT_IN_VERSION 15.0 MDR
PT_IN_VERSION 15.1 MDR
PT_IN_VERSION 16.0 MDR
PT_IN_VERSION 16.1 MDR
PT_IN_VERSION 17.0 MDR
PT_IN_VERSION 17.1 MDR
PT_IN_VERSION 18.0 MDR
PT_IN_VERSION 18.1 MDR
PT_IN_VERSION 19.0 MDR
PT_IN_VERSION 19.1 MDR
PT_IN_VERSION 8.0 MDR
PT_IN_VERSION 8.1 MDR
PT_IN_VERSION 9.0 MDR
PT_IN_VERSION 9.1 MDR
RXAUI 3108065 RXNORM
RXAUI 3145404 RXNORM
RXAUI 3145411 RXNORM
RXCUI 1022551 RXNORM
SID HP:0002274 HPO
SID HP:0007122 HPO
SID HP:0007150 HPO
SID HP:0007283 HPO
SMQ_TERM_ADDVERSION 10.0 MDR
SMQ_TERM_ADDVERSION 10.1 MDR
SMQ_TERM_CAT A MDR
SMQ_TERM_LEVEL 4 MDR
SMQ_TERM_LEVEL 5 MDR
SMQ_TERM_LMVERSION 10.1 MDR
SMQ_TERM_LMVERSION 13.1 MDR
SMQ_TERM_SCOPE 1 MDR
SMQ_TERM_SCOPE 2 MDR
SMQ_TERM_STATUS A MDR
SMQ_TERM_WEIGHT 0 MDR
SNOMED_CID 52448006 NDFRT
SNOMEDID D9-20200 SNOMEDCT_US
SOS A decrement in intellectual functioning of sufficient severity to interfere with occupational or social performance, or both. There is impairment of memory and abstract thinking, the ability to learn new skills, problem solving, and judgment. There is often also personality change or impairment in impulse control. Dementia in organic psychoses may be of a chronic or progressive nature, which if untreated are usually irreversible and terminal. AOD
SOS Excludes: dementia not classified as senile, presenile, or arteriosclerotic (294.10-294.11); psychoses classifiable to 295-298 occurring in the senium without dementia or delirium (295.0-298.8); senility with mental changes of nonpsychotic severity (310.1); transient organic psychotic conditions (293.0-293.9); dementia due to alcohol (291.0-291.2); dementia due to drugs (292.82) ICD9CM
SOS Excludes: mild memory disturbances, not amounting to dementia (310.89) ICD9CM
SUBSET_MEMBER 447562003~CORRELATIONID~447561005 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPADVICE~ALWAYS F03 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPCATEGORYID~447637006 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPGROUP~1 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPPRIORITY~1 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPRULE~TRUE SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPTARGET~F03 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~CORRELATIONID~447561005 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~ALWAYS F03.90 | DESCENDANTS NOT EXHAUSTIVELY MAPPED SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~IF AGE AT ONSET OF CLINICAL FINDING BEFORE 1.0 YEAR CHOOSE F84.3 | CONSIDER ADDITIONAL CODE TO IDENTIFY SPECIFIC CONDITION OR DISEASE | DESCENDANTS NOT EXHAUSTIVELY MAPPED | MAP OF SOURCE CONCEPT IS CONTEXT DEPENDENT SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPCATEGORYID~447637006 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPCATEGORYID~447639009 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPGROUP~1 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~1 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~2 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~IFA 445518008 | Age at onset of clinical finding (observable entity) | < 1.0 year SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~OTHERWISE TRUE SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~F03.90 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~F84.3 SNOMEDCT_US
SUBSET_MEMBER 900000000000497000~MAPTARGET~X002w SNOMEDCT_US
SUBSET_MEMBER 900000000000498005~MAPTARGET~D9-20200 SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
TERMUI T010817 MSH
TERMUI T367221 MSH
TH BIOETHICS (1989) MSH
TH NLM (2000) MSH
TYPE_ID 900000000000003001 SNOMEDCT_US
TYPE_ID 900000000000013009 SNOMEDCT_US

Additional Concept Data:  (none)

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