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| Terms & Properties |
Concept Unique Identifier (CUI): C0458219
Semantic Type: Disease or Syndrome
GARD Definition: Complex regional pain syndrome (CRPS) is a chronic pain condition that mainly affects the arm or leg after an injury. The main feature of CRPS is continuous, intense pain that is out of proportion to the severity of the injury. The pain gets worse over time and often spreads throughout the entire affected arm or leg. Other symptoms may include color and temperature changes of the skin over the affected area; skin sensitivity; sweating; and swelling. The underlying cause of CRPS is not known. Treatment aims to relieve pain and may include topical or oral medications; physical therapy; and/or a sympathetic nerve block. - this information is from GARD/ORDR/NCATS.
MEDLINEPLUS Definition:
Complex regional pain syndrome (CRPS) is a chronic pain condition. It causes intense pain, usually in the arms, hands, legs, or feet. It may happen after an injury, either to a nerve or to tissue in the affected area. Rest and time may only make it worse.
Symptoms in the affected area are
The cause of CRPS is unknown. There is no specific diagnostic test. Your doctor will diagnose CRPS based on your signs and symptoms.
There is no cure. It can get worse over time, and may spread to other parts of the body. Occasionally it goes away, either temporarily or for good. Treatment focuses on relieving the pain, and can include medicines, physical therapy, and nerve blocks.
NIH: National Institute of Neurological Disorders and Stroke
MSH Definition: Conditions characterized by pain involving an extremity or other body region, HYPERESTHESIA, and localized autonomic dysfunction following injury to soft tissue or nerve. The pain is usually associated with ERYTHEMA; SKIN TEMPERATURE changes, abnormal sudomotor activity (i.e., changes in sweating due to altered sympathetic innervation) or edema. The degree of pain and other manifestations is out of proportion to that expected from the inciting event. Two subtypes of this condition have been described: type I; (REFLEX SYMPATHETIC DYSTROPHY) and type II; (CAUSALGIA). (From Pain 1995 Oct;63(1):127-33)
Synonyms & Abbreviations: (see Synonym Details)
| Algodystrophy |
| Complex regional pain syndrome (disorder) |
| Complex regional pain syndrome NOS |
| Complex Regional Pain Syndromes [Disease/Finding] |
| Complex Regional Pain Syndromes |
| Complex regional pain syndrome |
| CRPS (Complex Regional Pain Syndromes) |
| CRPS - complex regional pain syndrome |
| CRPS |
| Pain Syndromes, Regional Complex |
| Reflex sympathetic dystrophy |
| Sudek atrophy |
External Source Codes: (none)
Other Properties:
| Name | Value | Source |
|---|---|---|
| ACTIVE | 1 | SNOMEDCT_US |
| AQL | BL CF CI CL CN CO DG DH DI DT EC EH EM EN EP ET GE HI IM ME MI MO NU PA PC PP PS PX RH RT SU TH UR VE VI | MSH |
| CASE_SIGNIFICANCE_ID | 900000000000017005 | SNOMEDCT_US |
| CASE_SIGNIFICANCE_ID | 900000000000448009 | SNOMEDCT_US |
| CHARACTERISTIC_TYPE_ID | 900000000000011006 | SNOMEDCT_US |
| CTV3ID | Xa0y5 | SNOMEDCT_US |
| DATE_CREATED | 11/03/1999 | MEDLINEPLUS |
| DATE_CREATED | 2013-01-09T00:04:00 | GARD |
| DATE_LAST_MODIFIED | 2013-01-09T00:04:00 | GARD |
| DC | 1 | MSH |
| DEFINITION_STATUS_ID | 900000000000074008 | SNOMEDCT_US |
| DISEASE_IDENTIFIER_ID | 14597 | GARD |
| DX | 20000101 | MSH |
| EFFECTIVE_TIME | 20020131 | SNOMEDCT_US |
| HAS_GARD_PAGE | true | GARD |
| HN | 2000 | MSH |
| IDENTIFIER_TYPE_ID | 1 | GARD |
| IS_ACTIVE | true | GARD |
| IS_RARE | true | GARD |
| IS_SPANISH | false | GARD |
| LAST_REVIEW_ACTION | Modified | GARD |
| LAST_REVIEW_DATE | 2009-06-24T00:00:00 | GARD |
| MDA | 19991103 | MSH |
| MESH_DEFINITION | Conditions characterized by pain involving an extremity or other body region, HYPERESTHESIA, and localized autonomic dysfunction following injury to soft tissue or nerve. The pain is usually associated with ERYTHEMA; SKIN TEMPERATURE changes, abnormal sudomotor activity (i.e., changes in sweating due to altered sympathetic innervation) or edema. The degree of pain and other manifestations is out of proportion to that expected from the inciting event. Two subtypes of this condition have been described: type I; (REFLEX SYMPATHETIC DYSTROPHY) and type II; (CAUSALGIA). (From Pain 1995 Oct;63(1):127-33) | NDFRT |
| MESH_DUI | D020918 | NDFRT |
| MESH_NAME | Complex Regional Pain Syndromes | NDFRT |
| MESH_UI | M0328368 | NDFRT |
| MMR | 20010725 | MSH |
| MN | C10.177.195 | MSH |
| MN | C10.668.829.250 | MSH |
| MODIFIER_ID | 900000000000451002 | SNOMEDCT_US |
| MP_HEALTH_TOPIC_URL | https://www.nlm.nih.gov/medlineplus/complexregionalpainsyndrome.html | MEDLINEPLUS |
| MP_OTHER_LANGUAGE_URL | Spanish https://www.nlm.nih.gov/medlineplus/spanish/complexregionalpainsyndrome.html | MEDLINEPLUS |
| MP_PRIMARY_INSTITUTE_URL | National Institute of Neurological Disorders and Stroke http://www.ninds.nih.gov/ | MEDLINEPLUS |
| NDFRT_KIND | DISEASE_KIND | NDFRT |
| NUI | N0000004218 | NDFRT |
| PM | 2000 | MSH |
| PRIMARY_PATH | 10064332$10040021$10029305$10029205$Complex regional pain syndrome$Sensory abnormalities NEC$Neurological disorders NEC$Nervous system disorders | MDR |
| PRIMARY_SOC | 10029205 | MDR |
| PT_IN_VERSION | 10.0 | MDR |
| PT_IN_VERSION | 10.1 | MDR |
| PT_IN_VERSION | 11.0 | MDR |
| PT_IN_VERSION | 11.1 | MDR |
| PT_IN_VERSION | 12.0 | MDR |
| PT_IN_VERSION | 12.1 | MDR |
| PT_IN_VERSION | 13.0 | MDR |
| PT_IN_VERSION | 13.1 | MDR |
| PT_IN_VERSION | 14.0 | MDR |
| PT_IN_VERSION | 14.1 | MDR |
| PT_IN_VERSION | 15.0 | MDR |
| PT_IN_VERSION | 15.1 | MDR |
| PT_IN_VERSION | 16.0 | MDR |
| PT_IN_VERSION | 16.1 | MDR |
| PT_IN_VERSION | 17.0 | MDR |
| PT_IN_VERSION | 17.1 | MDR |
| PT_IN_VERSION | 18.0 | MDR |
| PT_IN_VERSION | 18.1 | MDR |
| PT_IN_VERSION | 19.0 | MDR |
| PT_IN_VERSION | 19.1 | MDR |
| PT_IN_VERSION | 20.0 | MDR |
| PT_IN_VERSION | 20.1 | MDR |
| PT_IN_VERSION | 8.0 | MDR |
| PT_IN_VERSION | 8.1 | MDR |
| PT_IN_VERSION | 9.0 | MDR |
| PT_IN_VERSION | 9.1 | MDR |
| RARE_DISEASE_URL | http://rarediseases.info.nih.gov/gard/4647/complex-regional-pain-syndrome/resources/1 | GARD |
| RXAUI | 3127886 | RXNORM |
| RXAUI | 3134963 | RXNORM |
| RXAUI | 3134964 | RXNORM |
| RXAUI | 3217398 | RXNORM |
| RXCUI | 1022123 | RXNORM |
| SNOMED_CID | 128200000 | NDFRT |
| SUBSET_MEMBER | 447562003~CORRELATIONID~447561005 | SNOMEDCT_US |
| SUBSET_MEMBER | 447562003~MAPADVICE~ALWAYS G64 | SNOMEDCT_US |
| SUBSET_MEMBER | 447562003~MAPCATEGORYID~447637006 | SNOMEDCT_US |
| SUBSET_MEMBER | 447562003~MAPGROUP~1 | SNOMEDCT_US |
| SUBSET_MEMBER | 447562003~MAPPRIORITY~1 | SNOMEDCT_US |
| SUBSET_MEMBER | 447562003~MAPRULE~TRUE | SNOMEDCT_US |
| SUBSET_MEMBER | 447562003~MAPTARGET~G64 | SNOMEDCT_US |
| SUBSET_MEMBER | 6011000124106~CORRELATIONID~447561005 | SNOMEDCT_US |
| SUBSET_MEMBER | 6011000124106~MAPADVICE~ALWAYS G90.50 | DESCENDANTS NOT EXHAUSTIVELY MAPPED | SNOMEDCT_US |
| SUBSET_MEMBER | 6011000124106~MAPCATEGORYID~447637006 | SNOMEDCT_US |
| SUBSET_MEMBER | 6011000124106~MAPGROUP~1 | SNOMEDCT_US |
| SUBSET_MEMBER | 6011000124106~MAPPRIORITY~1 | SNOMEDCT_US |
| SUBSET_MEMBER | 6011000124106~MAPRULE~TRUE | SNOMEDCT_US |
| SUBSET_MEMBER | 6011000124106~MAPTARGET~G90.50 | SNOMEDCT_US |
| SUBSET_MEMBER | 900000000000497000~MAPTARGET~Xa0y5 | SNOMEDCT_US |
| SUBSET_MEMBER | 900000000000508004~ACCEPTABILITYID~900000000000548007 | SNOMEDCT_US |
| SUBSET_MEMBER | 900000000000508004~ACCEPTABILITYID~900000000000549004 | SNOMEDCT_US |
| SUBSET_MEMBER | 900000000000509007~ACCEPTABILITYID~900000000000548007 | SNOMEDCT_US |
| SUBSET_MEMBER | 900000000000509007~ACCEPTABILITYID~900000000000549004 | SNOMEDCT_US |
| TERMUI | T358368 | MSH |
| TERMUI | T368994 | MSH |
| TERMUI | T368995 | MSH |
| TH | NLM (2000) | MSH |
| TYPE_ID | 900000000000003001 | SNOMEDCT_US |
| TYPE_ID | 900000000000013009 | SNOMEDCT_US |
Additional Concept Data: (none)
URL to Bookmark: https://ncim-stage.nci.nih.gov/ncimbrowser/ConceptReport.jsp?dictionary=NCI Metathesaurus&code=C0458219
