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Anti-Glomerular Basement Membrane Disease (CUI C0403529) Suggest changes to this concept
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Terms & Properties

Concept Unique Identifier (CUI): C0403529

NCI Thesaurus Code: C84566  (see NCI Thesaurus info)

Semantic Type: Disease or Syndrome

NCIt Definition: An autoimmune disorder characterized by the production of autoantibodies against type IV collagen of the glomerular basement membrane of the kidney. In the majority of patients the immune reaction also extends to the alveolar capillary membrane of the lungs. The latter cases are referred to as Goodpasture Syndrome.

MSH Definition: An autoimmune disease of the KIDNEY and the LUNG. It is characterized by the presence of circulating autoantibodies targeting the epitopes in the non-collagenous domains of COLLAGEN TYPE IV in the basement membranes of kidney glomeruli (KIDNEY GLOMERULUS) and lung alveoli (PULMONARY ALVEOLI), and the subsequent destruction of these basement membranes. Clinical features include pulmonary alveolar hemorrhage and glomerulonephritis.

Synonyms & Abbreviations: (see Synonym Details)
Anti GBM - Antiglomerular basement membrane disease
Anti GBM Disease
ANTI GBM DIS
Anti Glomerular Basement Membrane Disease
ANTI GLOMERULAR BASEMENT MEMBRANE DIS
Anti-GBM Disease
Anti-GBM syndrome
Anti-glomerular basement membrane antibody disease
Anti-Glomerular Basement Membrane Disease [Disease/Finding]
Anti-glomerular basement membrane disease
ANTIGBM DISEASE
ANTIGLOMERULAR BASEMENT MEMBRANE DISEASE
Goodpasture Syndrome
Goodpasture's Syndrome
Lung Purpura with Nephritis

External Source Codes: 
NCI Thesaurus Code C84566 (see NCI Thesaurus info)

Other Properties: Property Definitions
Name Value Source
AQL BL CF CI CL CN CO DG DH DI DT EC EH EM EN EP ET GE HI IM ME MI MO NU PA PC PP PS PX RH RT SU TH UR VE VI MSH
CASE_SIGNIFICANCE_ID 900000000000017005 SNOMEDCT_US
CASE_SIGNIFICANCE_ID 900000000000020002 SNOMEDCT_US
DATE_CREATED 2013-01-09T00:04:00 GARD
DATE_CREATED 2015-01-22T00:04:00 GARD
DATE_LAST_MODIFIED 2013-01-09T00:04:00 GARD
DC 1 MSH
DISEASE_IDENTIFIER_ID 10135 GARD
DISEASE_IDENTIFIER_ID 32982 GARD
DISEASE_IDENTIFIER_ID 32983 GARD
DX 19980101 MSH
FX D050533 MSH
HN 1998 MSH
IDENTIFIER_SOURCE Orp GARD
IDENTIFIER_TYPE_ID 1 GARD
IS_ACTIVE true GARD
MDA 19970620 MSH
MESH_DEFINITION An autoimmune disease of the KIDNEY and the LUNG. It is characterized by the presence of circulating autoantibodies targeting the epitopes in the non-collagenous domains of COLLAGEN TYPE IV in the basement membranes of kidney glomeruli (KIDNEY GLOMERULUS) and lung alveoli (PULMONARY ALVEOLI), and the subsequent destruction of these basement membranes. Clinical features include pulmonary alveolar hemorrhage and glomerulonephritis. NDFRT
MESH_DUI D019867 NDFRT
MESH_NAME Anti-Glomerular Basement Membrane Disease NDFRT
MESH_UI M0029493 NDFRT
MMR 20120703 MSH
MN C08.381.483.156 MSH
MN C12.777.419.570.363.304 MSH
MN C13.351.968.419.570.363.304 MSH
MN C20.111.190 MSH
NDFRT_KIND DISEASE_KIND NDFRT
NUI N0000003962 NDFRT
PM 1998; for GOODPASTURE SYNDROME see GOODPASTURE SYNDROME 1965-2006 MSH
RXAUI 3109647 RXNORM
RXAUI 3109648 RXNORM
RXCUI 1025536 RXNORM
SNOMED_CID 236506009 NDFRT
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
TERMUI T018428 MSH
TERMUI T018429 MSH
TERMUI T018430 MSH
TERMUI T059129 MSH
TERMUI T059130 MSH
TH NLM (1965) MSH
TH NLM (1998) MSH
TH OMIM (2013) MSH
TH ORD (2010) MSH
TH UNK (19XX) MSH
TYPE_ID 900000000000013009 SNOMEDCT_US

Additional Concept Data:  (none)

URL to Bookmark: https://ncim-stage.nci.nih.gov/ncimbrowser/ConceptReport.jsp?dictionary=NCI Metathesaurus&code=C0403529

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