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Pregnenolone (CUI C0373704) Suggest changes to this concept
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Terms & Properties

Concept Unique Identifier (CUI): C0373704

NCI Thesaurus Code: C82315  (see NCI Thesaurus info)

Semantic Type: Organic Chemical

Semantic Type: Pharmacologic Substance

Semantic Type: Hormone

NCIt Definition: An endogenous steroid hormone synthesized from cholesterol, which can act either as a neuroactive steroid or as a prohormone for progestogens, mineralocorticoids, glucocorticoids, androgens, estrogens, and the neuroactive steroids.

CSP Definition: 21-carbon steroid, derived from cholesterol and found in steroid hormone-producing tissues.

MSH Definition: A 21-carbon steroid, derived from CHOLESTEROL and found in steroid hormone-producing tissues. Pregnenolone is the precursor to GONADAL STEROID HORMONES and the adrenal CORTICOSTEROIDS.

Synonyms & Abbreviations: (see Synonym Details)
3beta-Hydroxypregn-5-en-20-one
5 Pregnen 3 beta ol 20 one
5-Pregnen-3-beta-ol-20-one
Arthenolone
Bina-Skin
delta5-Pregnenolone
Enelone
Natolone
Pregn-5-en-20-one, 3-hydroxy-, (3beta)-
Pregnenolone (substance)
Pregnenolone [Chemical/Ingredient]
pregnenolone
Regnosone
Skinostelon

External Source Codes: 
NCI Thesaurus Code C82315 (see NCI Thesaurus info)
CAS Registry Number 145-13-1 (see NLM ChemIDplus info)
FDA UNII Code 73R90F7MQ8
NSC Code 1616 (see NCI DTP info)

Other Properties: Property Definitions
Name Value Source
ACTIVE 1 SNOMEDCT_US
AN do not confuse with PREGNANOLONE MSH
AQL AA AD AE AG AI AN BI BL CF CH CL CS CT DF EC GE HI IM IP ME PD PH PK PO RE SD SE ST TO TU UR MSH
CASE_SIGNIFICANCE_ID 900000000000448009 SNOMEDCT_US
CHARACTERISTIC_TYPE_ID 900000000000011006 SNOMEDCT_US
CHEBI_ID CHEBI:16581 NCI
Chemical_Formula C21H32O2 NCI
Contributing_Source CTRP NCI
Contributing_Source FDA NCI
CTV3ID X80GJ SNOMEDCT_US
DC 1 MSH
DEFINITION_STATUS_ID 900000000000074008 SNOMEDCT_US
DID 2406-6144 CSP
DX 19660101 MSH
EFFECTIVE_TIME 20020131 SNOMEDCT_US
FDA_UNII_CODE 73R90F7MQ8 NDFRT
HN ETOH descriptor 2000. AOD
LEVEL Ingredient NDFRT
MDA 19990101 MSH
MESH_DEFINITION A 21-carbon steroid, derived from CHOLESTEROL and found in steroid hormone-producing tissues. Pregnenolone is the precursor to GONADAL STEROID HORMONES and the adrenal CORTICOSTEROIDS. NDFRT
MESH_DUI D011284 NDFRT
MESH_NAME Pregnenolone NDFRT
MESH_UI M0017516 NDFRT
MMR 20160531 MSH
MN D04.210.500.745.745.725 MSH
MN D06.472.040.585.745 MSH
MN D06.472.334.851.687.500 MSH
MODIFIER_ID 900000000000451002 SNOMEDCT_US
NDFRT_KIND DRUG_KIND NDFRT
NDFRT_KIND INGREDIENT_KIND NDFRT
NUI N0000167506 NDFRT
NUI N0000188267 NDFRT
RN 73R90F7MQ8 MSH
RR 145-13-1 (Pregnenolone) MSH
RXAUI 3094229 RXNORM
RXAUI 3223245 RXNORM
RXAUI 3223410 RXNORM
RXAUI 3223415 RXNORM
RXAUI 3632374 RXNORM
RXAUI 5493529 RXNORM
RXAUI 5495264 RXNORM
RXAUI 5495265 RXNORM
RXAUI 824353 RXNORM
RXCUI 114052 RXNORM
RXN_ACTIVATED 01/28/2010 RXNORM
RXN_OBSOLETED 08/30/2007 RXNORM
SPL_SET_ID 04daddb5-009c-46e8-96be-334e489a6d6c MTHSPL
SPL_SET_ID 27b75090-088d-4a5a-ae6b-d97a5e8c651a MTHSPL
SPL_SET_ID 4c15779a-0107-464b-9fae-231bb54ac363 MTHSPL
SPL_SET_ID 61fa6e6e-42f5-4992-87b5-0770218abc8c MTHSPL
SPL_SET_ID 663affc1-0998-4231-b284-ff3e2a7807b9 MTHSPL
SPL_SET_ID 7271ea3b-9378-4a7a-a687-5e779e61513f MTHSPL
SPL_SET_ID 8b3af556-74fb-4054-80ca-2a973a9bc617 MTHSPL
SPL_SET_ID 8e8f1af0-ad54-4ec0-a809-2e682d1f89a7 MTHSPL
SPL_SET_ID 9c355245-260a-464b-abcf-95416b49caa3 MTHSPL
SPL_SET_ID a11f60fb-b149-4bf6-bbbb-acd06e6b08c0 MTHSPL
SPL_SET_ID be121012-2178-494c-bbc5-62f062cb6560 MTHSPL
SPL_SET_ID bf1d82fa-6846-4aa4-9390-c4c4e7a559dd MTHSPL
SPL_SET_ID d9d9e08a-25b6-4f59-8534-5bb1b5fe118f MTHSPL
SPL_SET_ID e231695a-165a-419e-b594-34f9522503ac MTHSPL
SPL_SET_ID f5b62b9d-5750-47f6-b497-4da06000506b MTHSPL
SUBSET_MEMBER 900000000000497000~MAPTARGET~X80GJ SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
TERMUI T033258 MSH
TERMUI T527741 MSH
TH FDA SRS (2014) MSH
TH INN (19XX) MSH
TH NLM (1966) MSH
TH NLM (2004) MSH
TYPE_ID 900000000000003001 SNOMEDCT_US
TYPE_ID 900000000000013009 SNOMEDCT_US
VANDF_RECORD 50.416^4869^Active/Master NDFRT
VANDF_RECORD 50.6^4831^Active/Master NDFRT
VUID 4032600 NDFRT

Additional Concept Data:  (none)

URL to Bookmark: https://ncim-stage.nci.nih.gov/ncimbrowser/ConceptReport.jsp?dictionary=NCI Metathesaurus&code=C0373704

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