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Iron (CUI C0302583) Suggest changes to this concept
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Terms & Properties

Concept Unique Identifier (CUI): C0302583

NCI Thesaurus Code: C598  (see NCI Thesaurus info)

Semantic Type: Element, Ion, or Isotope

NCIt Definition: An element with atomic symbol Fe, atomic number 26, and atomic weight 55.85.

RADLEX Definition: A metallic element found in certain minerals, in nearly all soils, and in mineral waters. It has the atomic symbol Fe, atomic number 26, and atomic weight 55.85. It is an essential constituent of hemoglobin, cytochrome, and other components of respiratory enzyme systems. Its chief functions are in the transport of oxygen to tissue (hemoglobin) and in cellular oxidation mechanisms. Depletion of iron stores may result in iron-deficiency anemia. Iron is used to build up the blood in anemia. (From Dorland, 27th ed) [MeSH]

PDQ Definition: An element with atomic symbol Fe, atomic number 26, and atomic weight 55.85. Check for active clinical trials using this agent. (NCI Thesaurus)

MEDLINEPLUS Definition: 

Iron is a mineral that our bodies need for many functions. For example, iron is part of hemoglobin, a protein which carries oxygen from our lungs throughout our bodies. It helps our muscles store and use oxygen. Iron is also part of many other proteins and enzymes.

Your body needs the right amount of iron. If you have too little iron, you may develop iron deficiency anemia. Causes of low iron levels include blood loss, poor diet, or an inability to absorb enough iron from foods. People at higher risk of having too little iron are young children and women who are pregnant or have periods.

Too much iron can damage your body. Taking too many iron supplements can cause iron poisoning. Some people have an inherited disease called hemochromatosis. It causes too much iron to build up in the body.

Centers for Disease Control and Prevention

NCI-GLOSS Definition: An important mineral the body needs to make hemoglobin, a substance in the blood that carries oxygen from the lungs to tissues throughout the body. Iron is also an important part of many other proteins and enzymes needed by the body for normal growth and development. It is found in red meat, fish, poultry, lentils, beans, and foods with iron added, such as cereal.

CSP Definition: metallic element found in certain minerals, in nearly all soils, and in mineral waters; atomic symbol Fe, atomic number 26, and atomic weight 55.85; it is an essential constituent of hemoglobin, cytochrome, and other components of respiratory enzyme systems; chief function is in the transport of oxygen to tissue (hemoglobin) and in cellular oxidation mechanisms.

MSH Definition: A metallic element with atomic symbol Fe, atomic number 26, and atomic weight 55.85. It is an essential constituent of HEMOGLOBINS; CYTOCHROMES; and IRON-BINDING PROTEINS. It plays a role in cellular redox reactions and in the transport of OXYGEN.

NPO Definition: An element with atomic number 26.

Synonyms & Abbreviations: (see Synonym Details)
7439-89-6
[TN410] IRON
Eisen
Fe - Iron
Fe element
ferric ion
Ferrum
fer
Fe
Hierro
Iron (substance)
Iron [Chemical/Ingredient]
Iron agent (substance)
Iron agent
Iron preparation
Iron, elemental
Iron, reduced
iron
Minerals - Iron
Niferex
Product containing iron (medicinal product)
Product containing iron
Reduced iron

External Source Codes: 
NCI Thesaurus Code C598 (see NCI Thesaurus info)
CAS Registry Number 7439-89-6 (see NLM ChemIDplus info)
FDA UNII Code E1UOL152H7
PDQ Closed Trial Search ID 42183
PDQ Open Trial Search ID 42183 (check for NCI PDQ open clinical trial info)

Other Properties: Property Definitions
Name Value Source
ACTIVE 1 SNOMEDCT_US
AN Fe-56; Fe(II) = FERROUS COMPOUNDS, Fe(III) = FERRIC COMPOUNDS; /defic: permitted but consider ANEMIA, IRON DEFICIENCY; pneumoconiosis caused by iron particles = SIDEROSIS; /metab: consider also IRON OVERLOAD; metabolic disorders = IRON METABOLISM DISORDERS MSH
AQL AD AE AG AN BL CF CH CL CT DF EC HI IM IP ME PD PH PK PO RE SD ST TO TU UR MSH
CASE_SIGNIFICANCE_ID 900000000000020002 SNOMEDCT_US
CASE_SIGNIFICANCE_ID 900000000000448009 SNOMEDCT_US
CHARACTERISTIC_TYPE_ID 900000000000011006 SNOMEDCT_US
CHEBI_ID CHEBI:18248 NCI
Chemical_Formula Fe NCI
CODE NPO_568 NPO
COMMENT Period4, Group=8, Z=26 RADLEX
Contributing_Source FDA NCI
CTV3ID i1z.. SNOMEDCT_US
CTV3ID X795v SNOMEDCT_US
CTV3ID XUWNi SNOMEDCT_US
DATE_CREATED 11/23/2010 MEDLINEPLUS
DC 1 MSH
DEFINITION_STATUS_ID 900000000000074008 SNOMEDCT_US
DID 1629-5100 CSP
DRUG_CLASS_TYPE 2 VANDF
DX 19600101 MSH
EFFECTIVE_TIME 20020131 SNOMEDCT_US
EFFECTIVE_TIME 20020731 SNOMEDCT_US
FDA_UNII_CODE E1UOL152H7 DRUGBANK
FDA_UNII_CODE E1UOL152H7 NDFRT
FR 11 MSH
FX D005290 MSH
FX D005293 MSH
FX D005296 MSH
FX D006485 MSH
FX D006486 MSH
FX D007503 MSH
FX D007504 MSH
FX D012806 MSH
FX D014168 MSH
HM D007501 MSH
HM D011134 MSH
HN /metabolism was IRON METABOLISM 1963-65 MSH
LEVEL Ingredient NDFRT
LEVEL VA Class NDFRT
LT TRD MSH
LT TRD MTH
LT TRD PDQ
MDA 19930201 MSH
MDA 19990101 MSH
MESH_DEFINITION A metallic element with atomic symbol Fe, atomic number 26, and atomic weight 55.85. It is an essential constituent of HEMOGLOBINS; CYTOCHROMES; and IRON-BINDING PROTEINS. It plays a role in cellular redox reactions and in the transport of OXYGEN. NDFRT
MESH_DUI D007501 NDFRT
MESH_NAME Iron NDFRT
MESH_UI M0011718 NDFRT
MMR 20001205 MSH
MMR 20130708 MSH
MN D01.268.556.412 MSH
MN D01.268.956.287 MSH
MN D01.552.544.412 MSH
MODIFIER_ID 900000000000451002 SNOMEDCT_US
MP_HEALTH_TOPIC_URL https://www.nlm.nih.gov/medlineplus/iron.html MEDLINEPLUS
MP_OTHER_LANGUAGE_URL Chinese - Simplified https://www.nlm.nih.gov/medlineplus/languages/iron.html#Chinese - Simplified MEDLINEPLUS
MP_OTHER_LANGUAGE_URL Chinese - Traditional https://www.nlm.nih.gov/medlineplus/languages/iron.html#Chinese - Traditional MEDLINEPLUS
MP_OTHER_LANGUAGE_URL Somali https://www.nlm.nih.gov/medlineplus/languages/iron.html#Somali MEDLINEPLUS
MP_OTHER_LANGUAGE_URL Spanish https://www.nlm.nih.gov/medlineplus/spanish/iron.html MEDLINEPLUS
MP_PRIMARY_INSTITUTE_URL NIH Office of Dietary Supplements https://ods.od.nih.gov/ MEDLINEPLUS
NCI_THESAURUS_CODE C598 PDQ
NDFRT_KIND DRUG_KIND NDFRT
NDFRT_KIND INGREDIENT_KIND NDFRT
NUI N0000006237 NDFRT
NUI N0000029436 NDFRT
NUI N0000146032 NDFRT
ORIG_STY Drug/agent PDQ
PA D014131 MSH
PARENT_CLASS 320 VANDF
PID 5422 PDQ
PM /metabolism was IRON METABOLISM 1963-65 MSH
RDF_ID NPO_568 NPO
RN 75534-60-0 MSH
RN E1UOL152H7 MSH
RR 7439-89-6 (Iron) MSH
RXAUI 2071723 RXNORM
RXAUI 2628506 RXNORM
RXAUI 3086434 RXNORM
RXAUI 3177283 RXNORM
RXAUI 3177284 RXNORM
RXAUI 3177285 RXNORM
RXAUI 3183001 RXNORM
RXAUI 3183039 RXNORM
RXAUI 3257927 RXNORM
RXAUI 3279312 RXNORM
RXAUI 5473608 RXNORM
RXAUI 606937 RXNORM
RXAUI 696001 RXNORM
RXCUI 1551653 RXNORM
RXCUI 68729 RXNORM
RXCUI 90176 RXNORM
RXN_ACTIVATED 01/28/2010 RXNORM
RXN_BN_CARDINALITY single RXNORM
RXN_OBSOLETED 10/01/2009 RXNORM
SC 1 MSH
SOS an orally administered polysaccharide-iron complex MSH
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SPL_SET_ID 0674df74-3e12-4484-9ffd-3c73f982a727 MTHSPL
SPL_SET_ID 06b3137f-15cb-4d30-8741-12f6231e8402 MTHSPL
SPL_SET_ID 06b963be-0817-469e-ad3a-8096324fbe94 MTHSPL
SPL_SET_ID 06c529fc-272c-f889-f5e5-7f3e5ef2c59d MTHSPL
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SPL_SET_ID 0722734e-5a30-47af-99a3-2512848b45cd MTHSPL
SPL_SET_ID 07b5f8eb-5e6b-6433-bc50-34459098e2eb MTHSPL
SPL_SET_ID 0883e94f-7987-4a17-a7c1-70655d827c17 MTHSPL
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SPL_SET_ID 0f832de0-d851-46cd-8302-a578b24932e9 MTHSPL
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SPL_SET_ID 11281d81-efc2-4436-85de-55ff78b16463 MTHSPL
SPL_SET_ID 118daf35-f942-4bb9-b71a-7ed1d29b54ea MTHSPL
SPL_SET_ID 1201d72d-6623-4254-8596-6aa50a2c6868 MTHSPL
SPL_SET_ID 13eca4b7-614b-49b4-b12b-95d1b8f3fcd3 MTHSPL
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SRC Adv Perit Dial 1992;8:444-7 MSH
SUBSET_MEMBER 900000000000497000~MAPTARGET~i1z.. SNOMEDCT_US
SUBSET_MEMBER 900000000000497000~MAPTARGET~X795v SNOMEDCT_US
SUBSET_MEMBER 900000000000497000~MAPTARGET~XUWNi SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
TERMUI T022556 MSH
TERMUI T241538 MSH
TH FDA SRS (2014) MSH
TH NLM (1993) MSH
TH POPLINE (1978) MSH
TYPE_ID 900000000000003001 SNOMEDCT_US
TYPE_ID 900000000000013009 SNOMEDCT_US
VAC TN410 NDFRT
VAC TN410 VANDF
VANDF_RECORD 50.416^248^Active/Master NDFRT
VANDF_RECORD 50.605^406^Active/Master NDFRT
VANDF_RECORD 50.6^2046^Active/Master NDFRT
VUID 4017653 NDFRT
VUID 4021883 NDFRT

Additional Concept Data:  (none)

URL to Bookmark: https://ncim-stage.nci.nih.gov/ncimbrowser/ConceptReport.jsp?dictionary=NCI Metathesaurus&code=C0302583

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