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duloxetine (CUI C0245561) Suggest changes to this concept
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Terms & Properties

Concept Unique Identifier (CUI): C0245561

NCI Thesaurus Code: C65495  (see NCI Thesaurus info)

Semantic Type: Organic Chemical

Semantic Type: Pharmacologic Substance

NCI-GLOSS Definition: A drug used to treat depression and peripheral neuropathy (pain, numbness, tingling, burning, or weakness in the hands or feet) that can occur with diabetes. It is also being studied in the treatment of peripheral neuropathy caused by certain anticancer drugs. Cymbalta increases the amount of certain chemicals in the brain that help relieve depression and pain. It is a type of serotonin and norepinephrine reuptake inhibitor.

Synonyms & Abbreviations: (see Synonym Details)
Duloxetine (substance)
Duloxetine
N-methyl-3-(1-naphthalenyloxy)-2-thiophenepropanamine
N-methyl-3-(1-naphthalenyloxy)-3-(2-thiophene)propanamide
Product containing duloxetine (medicinal product)
Product containing duloxetine

External Source Codes: 
NCI Thesaurus Code C65495 (see NCI Thesaurus info)
CAS Registry Number 116539-59-4 (see NLM ChemIDplus info)
FDA UNII Code O5TNM5N07U

Other Properties: Property Definitions
Name Value Source
Accepted_Therapeutic_Use_For Generalized Anxiety Disorder, Diabetic Peripheral Neuropathic Pain, Major Depressive Disorder NCI
ACTIVE 1 SNOMEDCT_US
CASE_SIGNIFICANCE_ID 900000000000448009 SNOMEDCT_US
CHARACTERISTIC_TYPE_ID 900000000000011006 SNOMEDCT_US
CHEBI_ID CHEBI:36795 NCI
Chemical_Formula C18H19NOS NCI
Contributing_Source FDA NCI
CTV3ID XUajM SNOMEDCT_US
CTV3ID XUajN SNOMEDCT_US
DEFINITION_STATUS_ID 900000000000074008 SNOMEDCT_US
EFFECTIVE_TIME 20040131 SNOMEDCT_US
FDA_UNII_CODE O5TNM5N07U DRUGBANK
FDA_UNII_CODE O5TNM5N07U NDFRT
LEVEL Example Part D Eligible Drugs USPMG
LEVEL Ingredient NDFRT
MODIFIER_ID 900000000000451002 SNOMEDCT_US
NDFRT_KIND DRUG_KIND NDFRT
NUI N0000148860 NDFRT
RN O5TNM5N07U MSH
RXAUI 2051165 RXNORM
RXAUI 2070668 RXNORM
RXAUI 3142899 RXNORM
RXAUI 3142900 RXNORM
RXAUI 3738134 RXNORM
RXAUI 6395288 RXNORM
RXAUI 6395323 RXNORM
RXCUI 72625 RXNORM
SID APRD00060 DRUGBANK
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SUBSET_MEMBER 900000000000497000~MAPTARGET~XUajM SNOMEDCT_US
SUBSET_MEMBER 900000000000497000~MAPTARGET~XUajN SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
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SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
TERMUI T000877082 MSH
TERMUI T192464 MSH
TERMUI T192465 MSH
TH FDA SRS (2013) MSH
TH INN (19XX) MSH
TH NLM (1989) MSH
TYPE_ID 900000000000003001 SNOMEDCT_US
TYPE_ID 900000000000013009 SNOMEDCT_US
VANDF_RECORD 50.416^4165^Active/Master NDFRT
VANDF_RECORD 50.6^3989^Active/Master NDFRT
VUID 4021477 NDFRT

Additional Concept Data:  (none)

URL to Bookmark: https://ncim-stage.nci.nih.gov/ncimbrowser/ConceptReport.jsp?dictionary=NCI Metathesaurus&code=C0245561

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