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gluconate (CUI C0220836) Suggest changes to this concept
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Terms & Properties

Concept Unique Identifier (CUI): C0220836

NCI Thesaurus Code: C61777  (see NCI Thesaurus info)

Semantic Type: Organic Chemical

Semantic Type: Pharmacologic Substance

Semantic Type: Biologically Active Substance

NCIt Definition: The carboxylic acid formed by the oxidation of the first carbon of glucose with antiseptic and chelating properties. Gluconic acid, found abundantly in plant, honey and wine, can be prepared by fungal fermentation process commercially. This agent and its derivatives can used in formulation of pharmaceuticals, cosmetics and food products as additive or buffer salts. Aqueous gluconic acid solution contains cyclic ester glucono delta lactone structure, which chelates metal ions and forms very stable complexes. In alkaline solution, this agent exhibits strong chelating activities towards anions, i.e. calcium, iron, aluminium, copper, and other heavy metals.

Synonyms & Abbreviations: (see Synonym Details)
D-gluconate
D-gluconic acid
gluconate
Gluconic acid (substance)
gluconic acid [Chemical/Ingredient]
Gluconic Acid

External Source Codes: 
NCI Thesaurus Code C61777 (see NCI Thesaurus info)
CAS Registry Number 133-42-6 (see NLM ChemIDplus info)
FDA UNII Code R4R8J0Q44B
NSC Code 77381 (see NCI DTP info)

Other Properties: Property Definitions
Name Value Source
ACTIVE 1 SNOMEDCT_US
CASE_SIGNIFICANCE_ID 900000000000448009 SNOMEDCT_US
CHEBI_ID CHEBI:24266 NCI
Chemical_Formula C6H12O7 NCI
Contributing_Source FDA NCI
CTV3ID XUFDF SNOMEDCT_US
DEFINITION_STATUS_ID 900000000000074008 SNOMEDCT_US
EFFECTIVE_TIME 20020131 SNOMEDCT_US
FDA_UNII_CODE R4R8J0Q44B DRUGBANK
FDA_UNII_CODE R4R8J0Q44B NDFRT
FDA_UNII_CODE W552L9Y4VZ NDFRT
FR 936 MSH
HM D005942 MSH
II D008094 MSH
II D015032 MSH
LEVEL Ingredient NDFRT
MDA 19810810 MSH
MESH_DUI C030691 NDFRT
MESH_NAME gluconic acid NDFRT
MESH_UI M0096893 NDFRT
MMR 20141027 MSH
NDFRT_KIND DRUG_KIND NDFRT
NDFRT_KIND INGREDIENT_KIND NDFRT
NUI N0000147009 NDFRT
NUI N0000147263 NDFRT
NUI N0000179369 NDFRT
RN R4R8J0Q44B MSH
RR 10101-21-0 MSH
RR 10361-31-6 MSH
RR 13005-35-1 MSH
RR 14906-97-9 MSH
RR 14933-21-2 MSH
RR 16775-10-3 MSH
RR 16960-18-2 MSH
RR 22830-45-1 MSH
RR 299-27-4 MSH
RR 29L5I58185 MSH
RR 33033-18-0 MSH
RR 35087-77-5 MSH
RR 35984-19-1 MSH
RR 3632-91-5 MSH
RR 50320-76-8 MSH
RR 50515-27-0 MSH
RR 50515-31-6 MSH
RR 526-95-4 (gluconic acid) MSH
RR 527-07-1 MSH
RR 53611-15-7 MSH
RR 60007-93-4 MSH
RR 60816-70-8 MSH
RR 6485-39-8 MSH
RR 71519-73-8 MSH
RR 78812-55-2 MSH
RR 82139-35-3 MSH
RR R6Q3791S76 MSH
RR T42NAD2KHC MSH
RR U6WSN5SQ1Z MSH
RXAUI 2071215 RXNORM
RXAUI 2071216 RXNORM
RXAUI 3137859 RXNORM
RXAUI 3137860 RXNORM
RXAUI 3163183 RXNORM
RXAUI 3163184 RXNORM
RXAUI 3163185 RXNORM
RXAUI 3163186 RXNORM
RXAUI 3260759 RXNORM
RXAUI 3260760 RXNORM
RXAUI 3260761 RXNORM
RXAUI 4627176 RXNORM
RXAUI 612278 RXNORM
RXCUI 70599 RXNORM
RXN_ACTIVATED 01/28/2010 RXNORM
RXN_OBSOLETED 08/30/2007 RXNORM
SC 1 MSH
SID EXPT01560 DRUGBANK
SOS zinc gluconate has anti-inflammatory activity; RN given refers to (D)-isomer; all RRs refers to (D)-isomer unless otherwise noted MSH
SPL_SET_ID 0f9bdd83-eb8d-473e-9ccd-3f16b244073e MTHSPL
SPL_SET_ID 150437b6-320e-4c69-a434-2a26a1f0b2e4 MTHSPL
SPL_SET_ID 19c04dcb-d6f2-4624-afd4-1c7b7ddcb85e MTHSPL
SPL_SET_ID 20e79dbb-8f33-469d-a7ca-29afde16a8ee MTHSPL
SPL_SET_ID 2ddcac37-80b4-46c2-a0fb-cb27c338c7e7 MTHSPL
SPL_SET_ID 3c12918e-d32f-4400-9af5-dfe90324d5e1 MTHSPL
SPL_SET_ID 4b4b02c7-b44a-483e-8e6b-79d994037490 MTHSPL
SPL_SET_ID 73b63f78-45ee-4103-930b-31ec573678e6 MTHSPL
SPL_SET_ID 73c67954-938f-4bcc-be48-a5a38094fee3 MTHSPL
SPL_SET_ID 7e8fe27f-ff82-48c1-9bf6-3c589c8e985d MTHSPL
SPL_SET_ID 90db80ed-c037-4e8f-a7f6-304a65f9fe22 MTHSPL
SPL_SET_ID 9322033d-dd65-4384-8100-f148cf2ab1e5 MTHSPL
SPL_SET_ID 9600a661-0684-4b53-bafe-34dbcf4e1884 MTHSPL
SPL_SET_ID b4444803-034c-4e22-9a21-9e07207df36e MTHSPL
SPL_SET_ID b53e5739-c9f6-44e4-8032-c2bf24fa8398 MTHSPL
SPL_SET_ID b7e59721-9cac-4d7a-8a07-e82b48232e2f MTHSPL
SPL_SET_ID c126e473-e9ae-4749-a5e9-07191ec8c1fb MTHSPL
SPL_SET_ID c19c8ed9-24ea-48a2-ad37-3fa3dfd15f06 MTHSPL
SPL_SET_ID efb50cd5-8cbf-4d14-b0b7-f7c2db31f314 MTHSPL
SPL_SET_ID f0779c98-8eca-4256-a27d-0136395846ba MTHSPL
SPL_SET_ID f83bbb1f-b1a9-42cd-ae46-168815cfefb5 MTHSPL
SRC Can J Biochem 1981;58(12):1397 MSH
SUBSET_MEMBER 900000000000497000~MAPTARGET~XUFDF SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
TERMUI T126889 MSH
TERMUI T126890 MSH
TERMUI T126891 MSH
TERMUI T126897 MSH
TH FDA SRS (2013) MSH
TH NLM (1981) MSH
TYPE_ID 900000000000003001 SNOMEDCT_US
TYPE_ID 900000000000013009 SNOMEDCT_US
VANDF_RECORD 50.416^1302^Active/Master NDFRT
VANDF_RECORD 50.416^1591^Active/Master NDFRT
VUID 4018700 NDFRT
VUID 4018986 NDFRT

Additional Concept Data:  (none)

URL to Bookmark: https://ncim-stage.nci.nih.gov/ncimbrowser/ConceptReport.jsp?dictionary=NCI Metathesaurus&code=C0220836

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