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Strychnine (CUI C0202474) Suggest changes to this concept
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Terms & Properties

Concept Unique Identifier (CUI): C0202474

NCI Thesaurus Code: C84183  (see NCI Thesaurus info)

Semantic Type: Pharmacologic Substance

Semantic Type: Hazardous or Poisonous Substance

Semantic Type: Organic Chemical

CSP Definition: extremely poisonous alkaloid which causes excitation of the central nervous system by blocking postsynaptic inhibition of neural impulses.

MSH Definition: An alkaloid found in the seeds of STRYCHNOS NUX-VOMICA. It is a competitive antagonist at glycine receptors and thus a convulsant. It has been used as an analeptic, in the treatment of nonketotic hyperglycinemia and sleep apnea, and as a rat poison.

Synonyms & Abbreviations: (see Synonym Details)
Strychnidin-10-one
Strychnine (substance)
Strychnine [Chemical/Ingredient]
Strychnine product (product)
Strychnine product
strychnine

External Source Codes: 
NCI Thesaurus Code C84183 (see NCI Thesaurus info)
CAS Registry Number 57-24-9 (see NLM ChemIDplus info)
FDA UNII Code H9Y79VD43J

Other Properties: Property Definitions
Name Value Source
ACTIVE 1 SNOMEDCT_US
AQL AA AD AE AG AI AN BI BL CF CH CL CS CT EC GE HI IM IP ME PD PH PK PO RE SD SE ST TO TU UR MSH
CASE_SIGNIFICANCE_ID 900000000000448009 SNOMEDCT_US
CHARACTERISTIC_TYPE_ID 900000000000011006 SNOMEDCT_US
CHEBI_ID CHEBI:28973 NCI
Chemical_Formula C21H22N2O2 NCI
Contributing_Source FDA NCI
CTV3ID x02ML SNOMEDCT_US
CTV3ID XUFYP SNOMEDCT_US
DC 1 MSH
DEFINITION_STATUS_ID 900000000000074008 SNOMEDCT_US
DID 0093-2956 CSP
DX 19600101 MSH
EFFECTIVE_TIME 20020131 SNOMEDCT_US
FDA_UNII_CODE H9Y79VD43J NDFRT
HN NUX VOMICA was heading 1963-78 MSH
LEVEL Ingredient NDFRT
MDA 19990101 MSH
MESH_DEFINITION An alkaloid found in the seeds of STRYCHNOS NUX-VOMICA. It is a competitive antagonist at glycine receptors and thus a convulsant. It has been used as an analeptic, in the treatment of nonketotic hyperglycinemia and sleep apnea, and as a rat poison. NDFRT
MESH_DUI D013331 NDFRT
MESH_NAME Strychnine NDFRT
MESH_UI M0020628 NDFRT
MMR 20160601 MSH
MN D03.132.436.681.722 MSH
MN D03.633.100.473.402.681.722 MSH
MODIFIER_ID 900000000000451002 SNOMEDCT_US
NDFRT_KIND DRUG_KIND NDFRT
NDFRT_KIND INGREDIENT_KIND NDFRT
NUI N0000005984 NDFRT
NUI N0000148019 NDFRT
OL use STRYCHNINE to search NUX VOMICA 1966-78 MSH
PA D003292 MSH
PA D011042 MSH
PA D018684 MSH
PM NUX VOMICA was heading 1963-78 MSH
RN H9Y79VD43J MSH
RR 57-24-9 (Strychnine) MSH
RR O642E96711 MSH
RXAUI 2074515 RXNORM
RXAUI 3235658 RXNORM
RXAUI 3235659 RXNORM
RXAUI 3240890 RXNORM
RXAUI 3240892 RXNORM
RXAUI 3240893 RXNORM
RXAUI 3861155 RXNORM
RXAUI 4217980 RXNORM
RXAUI 592557 RXNORM
RXCUI 66422 RXNORM
SPL_SET_ID 1171df60-cc90-4730-9671-ecf284f3ae42 MTHSPL
SPL_SET_ID 11cad8ba-6914-420e-bab0-4ca37d33f2e6 MTHSPL
SPL_SET_ID 237bd9b8-082a-4df9-bc82-aea4ff157851 MTHSPL
SPL_SET_ID 24363142-6457-1cfe-e054-00144ff8d46c MTHSPL
SPL_SET_ID 28794e4d-a2a0-1d86-24b4-eb4256826ff5 MTHSPL
SPL_SET_ID 2cfa9c0d-34b4-4333-b087-72e29e34e275 MTHSPL
SPL_SET_ID 4db6e74a-ca03-d7b7-d697-78225ea38d5e MTHSPL
SPL_SET_ID 4ee3e461-1855-4f10-878b-ca7a647ccdf1 MTHSPL
SPL_SET_ID 52f3f024-8461-1b97-9964-bef905172457 MTHSPL
SPL_SET_ID 58d8459e-85d7-47a5-88a2-ffbe0861c4bf MTHSPL
SPL_SET_ID 5fbdf681-32dc-702c-0afd-8844056f5564 MTHSPL
SPL_SET_ID 643ad951-a10c-88a7-277c-d756e4b47966 MTHSPL
SPL_SET_ID 6b02dbf8-bde2-ad93-452c-3d879395f3f1 MTHSPL
SPL_SET_ID 6d223bcb-b649-4881-928f-210c6d6d6002 MTHSPL
SPL_SET_ID 725509bf-e1e6-bf60-bd2e-014219ba8327 MTHSPL
SPL_SET_ID 751a0887-483c-9cd6-86a6-fb81626f0d0a MTHSPL
SPL_SET_ID 7682287b-c982-572b-78fc-2175198f7ef3 MTHSPL
SPL_SET_ID 77b37cb6-9196-c3df-b91a-09dfaf2e81d5 MTHSPL
SPL_SET_ID 7a5ea24a-2b47-e3d6-ea3d-1acaa621fb79 MTHSPL
SPL_SET_ID 7cca960f-25db-fea9-8ede-7ce18c42a9eb MTHSPL
SPL_SET_ID 7d643143-7305-bf15-cdeb-d0a6dffc1ba5 MTHSPL
SPL_SET_ID 7e7f186f-b6f4-1f25-620b-83cb3e8363f6 MTHSPL
SPL_SET_ID 862d0d52-7a63-196f-daca-53919a3c6de5 MTHSPL
SPL_SET_ID 87d8ef34-3fd2-3700-4258-89ee9fe0f9e0 MTHSPL
SPL_SET_ID 937ce362-2e78-4f71-ac00-9102f2f79ceb MTHSPL
SPL_SET_ID 943d5364-3966-09ba-9566-c00029529063 MTHSPL
SPL_SET_ID a5e9fb1f-ab17-10cb-d2e5-af21a73461e2 MTHSPL
SPL_SET_ID a9799afd-12fc-1408-0962-a183c8de5f77 MTHSPL
SPL_SET_ID af213a41-ff9b-4a93-bc3f-36eeef1263e9 MTHSPL
SPL_SET_ID b390faee-c60b-f9e6-c77f-80acdeaf0036 MTHSPL
SPL_SET_ID bc31e919-e92f-4d4e-8dae-cc2fd93dc78d MTHSPL
SPL_SET_ID c5328b63-470a-5450-821d-c44804c8b3a7 MTHSPL
SPL_SET_ID c9b8a0f2-d7db-4a2e-9d41-9004b1712848 MTHSPL
SPL_SET_ID cc3eac44-a75d-9768-b9c0-d81dca9ecefa MTHSPL
SPL_SET_ID d3f2d68b-9b8f-1529-93c9-8335198ea5a9 MTHSPL
SPL_SET_ID e14d4d19-2946-d85c-83de-91f0ca5ba5d3 MTHSPL
SUBSET_MEMBER 900000000000497000~MAPTARGET~x02ML SNOMEDCT_US
SUBSET_MEMBER 900000000000497000~MAPTARGET~XUFYP SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
TERMUI T039136 MSH
TH FDA SRS (2014) MSH
TH NLM (1966) MSH
TYPE_ID 900000000000003001 SNOMEDCT_US
TYPE_ID 900000000000013009 SNOMEDCT_US
VANDF_RECORD 50.416^2559^Active/Master NDFRT
VANDF_RECORD 50.6^1697^Active/Master NDFRT
VUID 4019934 NDFRT

Additional Concept Data:  (none)

URL to Bookmark: https://ncim-stage.nci.nih.gov/ncimbrowser/ConceptReport.jsp?dictionary=NCI Metathesaurus&code=C0202474

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