skip navigation links
National Cancer Institute
Enterprise Vocabulary Services
Box
NCIm Version: 201706 (Browser Version 2.9, using LexEVS 6.5.1)
SearchBox Top
SearchBox Bottom
Guanidine (CUI C0120446) Suggest changes to this concept
Add to Cart

Terms & Properties

Concept Unique Identifier (CUI): C0120446

NCI Thesaurus Code: C77851  (see NCI Thesaurus info)

Semantic Type: Pharmacologic Substance

Semantic Type: Organic Chemical

Semantic Type: Biologically Active Substance

MSH Definition: A strong organic base existing primarily as guanidium ions at physiological pH. It is found in the urine as a normal product of protein metabolism. It is also used in laboratory research as a protein denaturant. (From Martindale, the Extra Pharmacopoeia, 30th ed and Merck Index, 12th ed) It is also used in the treatment of myasthenia and as a fluorescent probe in HPLC.

Synonyms & Abbreviations: (see Synonym Details)
aminoformamidine
Aminomethanamidine
Carbamamidine
carbamidine
Guanidine (product)
Guanidine (substance)
Guanidine [Chemical/Ingredient]
Guanidine
Guanidinium
Guanidin
Gu
H2N-C(=NH)-NH2
Imidourea
iminourea

External Source Codes: 
NCI Thesaurus Code C77851 (see NCI Thesaurus info)
CAS Registry Number 113-00-8 (see NLM ChemIDplus info)
FDA UNII Code JU58VJ6Y3B

Other Properties: Property Definitions
Name Value Source
ACTIVE 1 SNOMEDCT_US
AQL AA AD AE AG AI AN BL CF CH CL CS CT EC HI IM IP ME PD PK PO RE SD ST TO TU UR MSH
CASE_SIGNIFICANCE_ID 900000000000020002 SNOMEDCT_US
CHARACTERISTIC_TYPE_ID 900000000000011006 SNOMEDCT_US
CHEBI_ID CHEBI:42820 NCI
Chemical_Formula CH5N3 NCI
Contributing_Source FDA NCI
CTV3ID XU2HP SNOMEDCT_US
CTV3ID XUbCr SNOMEDCT_US
DC 1 MSH
DEFINITION_STATUS_ID 900000000000074008 SNOMEDCT_US
DID 1356-9885 CSP
DX 19980101 MSH
EFFECTIVE_TIME 20020131 SNOMEDCT_US
EFFECTIVE_TIME 20040731 SNOMEDCT_US
FDA_UNII_CODE JU58VJ6Y3B DRUGBANK
FDA_UNII_CODE JU58VJ6Y3B NDFRT
HN 98; use GUANIDINE (NM) 1974-97 MSH
LEVEL Example Part D Eligible Drugs USPMG
LEVEL Ingredient NDFRT
MDA 19970620 MSH
MESH_DEFINITION A strong organic base existing primarily as guanidium ions at physiological pH. It is found in the urine as a normal product of protein metabolism. It is also used in laboratory research as a protein denaturant. (From Martindale, the Extra Pharmacopoeia, 30th ed and Merck Index, 12th ed) It is also used in the treatment of myasthenia and as a fluorescent probe in HPLC. NDFRT
MESH_DUI D019791 NDFRT
MESH_NAME Guanidine NDFRT
MESH_UI M0029365 NDFRT
MMR 20130708 MSH
MN D02.078.370.472 MSH
MODIFIER_ID 900000000000451002 SNOMEDCT_US
NDFRT_KIND DRUG_KIND NDFRT
NDFRT_KIND INGREDIENT_KIND NDFRT
NUI N0000006899 NDFRT
NUI N0000147863 NDFRT
PM 98; GUANIDINE was indexed under GUANIDINES 1974-97 MSH
RN JU58VJ6Y3B MSH
RR 113-00-8 (Guanidine) MSH
RR 1184-68-5 (unspecified sulfate) MSH
RR 1763-07-1 (unspecified phosphate) MSH
RR 19227-70-4 (mono-HI) MSH
RR 19244-98-5 (mono-HBr) MSH
RR 3YQC9ZY4YB MSH
RR 50-01-1 (mono-HCl) MSH
RR 52470-25-4 (nitrate) MSH
RR 594-14-9 (sulfate 2:1) MSH
RR 64120-25-8 (monohydrate) MSH
RR 646-34-4 (sulfate 1:1) MSH
RR 77160-75-9 (sulfite 1:1) MSH
RR 87862-39-3 (14C-labeled cpd) MSH
RR B542239A4E MSH
RXAUI 2071311 RXNORM
RXAUI 2355711 RXNORM
RXAUI 3164385 RXNORM
RXAUI 3164386 RXNORM
RXAUI 3167203 RXNORM
RXAUI 3167207 RXNORM
RXAUI 3167223 RXNORM
RXAUI 6395452 RXNORM
RXCUI 50675 RXNORM
SID APRD01008 DRUGBANK
SID EXPT01546 DRUGBANK
SNOMEDID C-67101 SNOMEDCT_US
SNOMEDID C-67129 SNOMEDCT_US
SPL_SET_ID 903fbd33-e5d9-41fb-9414-7bd6f42a8593 MTHSPL
SUBSET_MEMBER 900000000000497000~MAPTARGET~XU2HP SNOMEDCT_US
SUBSET_MEMBER 900000000000497000~MAPTARGET~XUbCr SNOMEDCT_US
SUBSET_MEMBER 900000000000498005~MAPTARGET~C-67101 SNOMEDCT_US
SUBSET_MEMBER 900000000000498005~MAPTARGET~C-67129 SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
TERMUI T058851 MSH
TERMUI T058852 MSH
TH FDA SRS (2014) MSH
TH NLM (1998) MSH
TYPE_ID 900000000000003001 SNOMEDCT_US
TYPE_ID 900000000000013009 SNOMEDCT_US
VANDF_RECORD 50.416^2395^Active/Master NDFRT
VUID 4019772 NDFRT

Additional Concept Data:  (none)

URL to Bookmark: https://ncim-stage.nci.nih.gov/ncimbrowser/ConceptReport.jsp?dictionary=NCI Metathesaurus&code=C0120446

Mainbox Bottom