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Permethrin (CUI C0070455) Suggest changes to this concept
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Terms & Properties

Concept Unique Identifier (CUI): C0070455

NCI Thesaurus Code: C29354  (see NCI Thesaurus info)

Semantic Type: Pharmacologic Substance

Semantic Type: Organic Chemical

Semantic Type: Hazardous or Poisonous Substance

NCIt Definition: A synthetic pyrethroid and neurotoxin. Permethrin affects the neuronal membrane by blocking the movement of sodium ions from outside to inside the neuronal cell membrane thereby disrupting the sodium channel current that regulates the polarization of the membrane. This leads to delayed repolarization and subsequent paralysis of the nervous system. Permethrin is used to eradicate parasites such as head lice, ticks and scabies from humans and animals.

MSH Definition: A pyrethroid insecticide commonly used in the treatment of LICE INFESTATIONS and SCABIES.

Synonyms & Abbreviations: (see Synonym Details)
(+/-)-3-Phenoxybenzyl 3-(2,2-Dichlorovinyl)-2,2-Dimethylcyclopropanecarboxylate
(3-Phenoxyphenyl)methyl (+-)-cis,trans-3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarboxylate
(m-Phenoxybenzyl)-cis,trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate
3-(2,2-Dichloroethenyl)-2,2-dimethylcyclopropane carboxylic acid, (3-phenoxyphenyl) methyl ester
3-Phenoxybenzyl-(+-)-cis,trans-2,2-dichlorovinyl-2,2-dimethyl-cyclopropylcarboxylic acid, ester
3-Phenoxybenzyl-cis,trans-(1RS)-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate
cyclopropanecarboxylic acid, 3-(2,2-dichloroethenyl)-2,2-dimethyl-, (3-phenoxyphenyl)methyl ester
Elimite
M-Phenoxybenzyl (+/-)-3-(2,2-Dichlorovinyl)-2,2-Dimethylcyclopropanecarboxylate
Nix Cream Rinse
Nix
Permethrin (substance)
Permethrin [Chemical/Ingredient]
Permethrin
Product containing permethrin (medicinal product)
Product containing permethrin

External Source Codes: 
NCI Thesaurus Code C29354 (see NCI Thesaurus info)
CAS Registry Number 52645-53-1 (see NLM ChemIDplus info)
FDA UNII Code 509F88P9SZ

Other Properties: Property Definitions
Name Value Source
ACTIVE 1 SNOMEDCT_US
AQL AA AD AE AG AI AN BL CF CH CL CS CT EC HI IM IP ME PD PK PO RE SD ST TO TU UR MSH
CASE_SIGNIFICANCE_ID 900000000000017005 SNOMEDCT_US
CASE_SIGNIFICANCE_ID 900000000000448009 SNOMEDCT_US
CHARACTERISTIC_TYPE_ID 900000000000011006 SNOMEDCT_US
CHEBI_ID CHEBI:34911 NCI
Chemical_Formula C21H20Cl2O3 NCI
Contributing_Source FDA NCI
CTV3ID mg8.. SNOMEDCT_US
CTV3ID XUc7v SNOMEDCT_US
DC 1 MSH
DEFINITION_STATUS_ID 900000000000074008 SNOMEDCT_US
DX 20020101 MSH
EFFECTIVE_TIME 20020131 SNOMEDCT_US
EFFECTIVE_TIME 20040731 SNOMEDCT_US
FDA_UNII_CODE 509F88P9SZ DRUGBANK
FDA_UNII_CODE 509F88P9SZ NDFRT
HN 2002; use PYMETHRIN (NM) 1975-2001 MSH
LEVEL Example Part D Eligible Drugs USPMG
LEVEL Ingredient NDFRT
LT TRD MSH
LT TRD MTH
MDA 20010725 MSH
MESH_DEFINITION A pyrethroid insecticide commonly used in the treatment of LICE INFESTATIONS and SCABIES. NDFRT
MESH_DUI D026023 NDFRT
MESH_NAME Permethrin NDFRT
MESH_UI M0056353 NDFRT
MMR 20130708 MSH
MN D02.455.849.575.812.636 MSH
MODIFIER_ID 900000000000451002 SNOMEDCT_US
NDFRT_KIND DRUG_KIND NDFRT
NDFRT_KIND INGREDIENT_KIND NDFRT
NUI N0000006719 NDFRT
NUI N0000147078 NDFRT
PA D004791 MSH
PA D007306 MSH
PM 2002; PERMETHRIN was indexed under PYRETHRINS 1978-2001 & PYRETHRUM 1975-1977 MSH
RN 0 MSH
RN 509F88P9SZ MSH
RR 51877-74-8 ((1R-trans)-isomer) MSH
RR 52341-32-9 ((trans-(+-))-isomer) MSH
RR 52341-33-0 ((cis-(+-))-isomer) MSH
RR 52645-53-1 (Permethrin) MSH
RR 54774-45-7 ((1R-cis)-isomer) MSH
RR 54774-46-8 ((1S-cis)-isomer) MSH
RR 54774-47-9 ((1S-trans)-isomer) MSH
RR 61949-76-6 ((cis)-isomer) MSH
RR 61949-77-7 ((trans)-isomer) MSH
RXAUI 1177769 RXNORM
RXAUI 1181156 RXNORM
RXAUI 2072897 RXNORM
RXAUI 2621958 RXNORM
RXAUI 3090928 RXNORM
RXAUI 3093283 RXNORM
RXAUI 3093284 RXNORM
RXAUI 3213169 RXNORM
RXAUI 3213170 RXNORM
RXAUI 3219332 RXNORM
RXAUI 3219333 RXNORM
RXAUI 3259884 RXNORM
RXAUI 3608013 RXNORM
RXAUI 450371 RXNORM
RXCUI 216875 RXNORM
RXCUI 218756 RXNORM
RXCUI 33199 RXNORM
RXN_BN_CARDINALITY single RXNORM
SPL_SET_ID 0494e7d2-70a5-44e5-a026-559fdf1808dd MTHSPL
SPL_SET_ID 095aec7a-c02f-4907-b9b0-b8a77f704e5b MTHSPL
SPL_SET_ID 2300343d-d5bf-4470-9d06-fc71150016f3 MTHSPL
SPL_SET_ID 27d6edc8-e581-44aa-9c1d-3ab7d56f15be MTHSPL
SPL_SET_ID 2b06f503-def4-4aaf-986b-72cf08a9b87b MTHSPL
SPL_SET_ID 3121896e-d359-45be-90cf-1ad701ba58ad MTHSPL
SPL_SET_ID 3d757b15-0bae-45c1-8fae-6ebdf0f7d560 MTHSPL
SPL_SET_ID 3f57a849-1978-4c80-b985-e299e5db9188 MTHSPL
SPL_SET_ID 4b90084e-b84b-4906-bb0e-a61da43f3267 MTHSPL
SPL_SET_ID 4de55a80-67d6-42c0-a6fc-57b89400c5b3 MTHSPL
SPL_SET_ID 5db4d503-dcf3-4666-bc47-a319c854c42f MTHSPL
SPL_SET_ID 6b635c81-3afe-4943-ac18-a0e7b0c427f2 MTHSPL
SPL_SET_ID 6d7c7436-8bb4-48df-917f-4aa0a2721173 MTHSPL
SPL_SET_ID 6efbbff4-db09-4d9d-93dd-6b6ce9271514 MTHSPL
SPL_SET_ID 769373fb-87ed-4400-8244-c0e8f2683813 MTHSPL
SPL_SET_ID 7d83219d-0def-4527-9713-ff92d40b5975 MTHSPL
SPL_SET_ID 84c2c27a-02e7-4153-8a1e-02499e56749b MTHSPL
SPL_SET_ID 85cf8bec-fc99-48da-8efc-c6ad0915300d MTHSPL
SPL_SET_ID 8bc95ef1-ea25-4ae7-a6e4-57e3e300a2c1 MTHSPL
SPL_SET_ID 8e6ee1db-6159-48a5-ba1d-93d148a2ab58 MTHSPL
SPL_SET_ID 94e9caae-9bd9-4020-8934-eefeb8d50ac3 MTHSPL
SPL_SET_ID 98ed8a61-501b-409b-b30c-9d68d4c16f9a MTHSPL
SPL_SET_ID 9b44bf94-62c9-49d8-97ec-cf475824eb35 MTHSPL
SPL_SET_ID 9f4cad52-e1fe-4c7b-ab08-deeef4a86ca9 MTHSPL
SPL_SET_ID a2ca3116-36bb-4ed0-a750-b799cbd03d33 MTHSPL
SPL_SET_ID a8d4eb78-4556-4315-815c-7f05e691b7aa MTHSPL
SPL_SET_ID aa294be5-9015-4f6a-8a92-a71a2b22d1b2 MTHSPL
SPL_SET_ID ad568fc3-8e4a-4cff-9bbb-35312451c43b MTHSPL
SPL_SET_ID bbc35573-c577-4618-8edd-6b0000115b63 MTHSPL
SPL_SET_ID bdb796aa-a7d1-4476-988f-2b4a9519788f MTHSPL
SPL_SET_ID c62f5903-b714-46c5-83a7-d87bae4d8af3 MTHSPL
SPL_SET_ID c6c509bb-658e-46eb-a844-8323ecd115de MTHSPL
SPL_SET_ID cc8a504a-f427-4382-b73a-6a044d2877d6 MTHSPL
SPL_SET_ID cce3b28b-7761-4045-a631-380ed8e529c2 MTHSPL
SPL_SET_ID cdd1a3d3-1793-490f-b09a-4f189bfdbd53 MTHSPL
SPL_SET_ID dc021770-ca43-4f33-93b7-b5814c1f207e MTHSPL
SPL_SET_ID fbcb7c07-4438-4b34-bf8a-180ed7af2071 MTHSPL
SUBSET_MEMBER 900000000000497000~MAPTARGET~mg8.. SNOMEDCT_US
SUBSET_MEMBER 900000000000497000~MAPTARGET~XUc7v SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
TERMUI T086340 MSH
TERMUI T086341 MSH
TERMUI T086342 MSH
TERMUI T086352 MSH
TERMUI T086356 MSH
TH FDA SRS (2014) MSH
TH INN (19XX) MSH
TH NLM (2002) MSH
TH USAN (19XX) MSH
TYPE_ID 900000000000003001 SNOMEDCT_US
TYPE_ID 900000000000013009 SNOMEDCT_US
VANDF_RECORD 50.416^1377^Active/Master NDFRT
VANDF_RECORD 50.6^1117^Active/Master NDFRT
VUID 4018775 NDFRT

Additional Concept Data:  (none)

URL to Bookmark: https://ncim-stage.nci.nih.gov/ncimbrowser/ConceptReport.jsp?dictionary=NCI Metathesaurus&code=C0070455

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