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medroxyprogesterone acetate (CUI C0065864) Suggest changes to this concept
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Terms & Properties

Concept Unique Identifier (CUI): C0065864

NCI Thesaurus Code: C1155  (see NCI Thesaurus info)

Semantic Type: Hormone

Semantic Type: Pharmacologic Substance

NCIt Definition: A synthetic, acetate derivative of the sex hormone progesterone. Medroxyprogesterone 17-acetate (NCI04)

NCI-GLOSS Definition: A drug used to prevent endometrial cancer. It is also used to treat menstrual disorders and as a form of birth control. It is a form of the female hormone progesterone and belongs to the family of drugs called progestins.

MSH Definition: A synthetic progestin that is derived from 17-hydroxyprogesterone. It is a long-acting contraceptive that is effective both orally or by intramuscular injection and has also been used to treat breast and endometrial neoplasms.

Synonyms & Abbreviations: (see Synonym Details)
(6 alpha)-17-(Acetoxy)-6-methylpregn-4-ene-3,20-dione
(6alpha)-17-(Acetyloxy)-6-methylpreg-4-ene-3,20-dione
(6alpha)-17-(Acetyloxy)-6-methylpregn-4-ene-3,20-dione
17-(Acetyloxy)-6alpha-methylpregn-4-ene-3,20-dione
17-Acetoxy-6alpha-methylprogesterone
17-Acetoxy-6α-methylprogesterone
17-Hydroxy-6alpha-methylpregn-4-ene-3,20-dione Acetate
17Alpha-acetoxy-6alpha-methylprogesterone
17alpha-Hydroxy-6alpha-methylprogesterone acetate
17α-hydroxy-6α-methylprogesterone acetate
6 alpha Methyl 17alpha hydroxyprogesterone Acetate
6-alpha-Methyl-17-alpha-acetoxyprogesterone
6-alpha-Methyl-17-alpha-hydroxyprogesterone acetate
6-Alpha-methyl-17alpha-acetoxyprogesterone
6-alpha-Methyl-17alpha-hydroxyprogesterone Acetate
6alpha-Methyl-17-acetoxy progesterone
6alpha-Methyl-17alpha-hydroxyprogesterone acetate
6alpha-Methyl-4-pregnene-3,20-dion-17alpha-ol acetate
6α-Methyl-17-acetoxy progesterone
6α-Methyl-17α-hydroxyprogesterone acetate
Amen
Aragest
Ciclotal
Clinofem
Clinovir
Cycrin
Depo Medroxyprogesterone Acetate
Depo Provera
Depo-Clinovir
Depo-Medroxyprogesterone Acetate
Depo-provera
DepoProvera
Depot-Medroxyprogestereone Acetate
Farlutal
G-Farlutal
Gestapuran
Hysron
Lutoral
Medroxyacetate progesterone
Medroxyprogesterone 17 Acetate
Medroxyprogesterone 17-acetate
Medroxyprogesterone acetate (substance)
MEDROXYPROGESTERONE ACETATE 17
Medroxyprogesterone Acetate [Chemical/Ingredient]
Medroxyprogesterone acetate preparation
Medroxyprogesterone Acetate
Medroxyprogesteroni Acetas
Methylacetoxyprogesterone
Metigestrona
Metipregnone
MPA
Nadigest (vet)
Nadigest
Nidaxin (vet)
Nidaxin
Oragest
Perlutex
Pregn-4-ene-3,20-dione, 17-(acetyloxy)-6-methyl-, (6alpha)-
Prodasone
Product containing medroxyprogesterone acetate (medicinal product)
Product containing medroxyprogesterone acetate
Provera
Sodelut G
Veramix

External Source Codes: 
NCI Thesaurus Code C1155 (see NCI Thesaurus info)
CAS Registry Number 71-58-9 (see NLM ChemIDplus info)
FDA UNII Code C2QI4IOI2G
NSC Code 21171 (see NCI DTP info)
NSC Code 26386 (see NCI DTP info)

Other Properties: Property Definitions
Name Value Source
ACTIVE 1 SNOMEDCT_US
AQL AA AD AE AG AI AN BL CF CH CL CS CT EC HI IM IP ME PD PK PO RE SD ST TO TU UR MSH
CASE_SIGNIFICANCE_ID 900000000000448009 SNOMEDCT_US
CHARACTERISTIC_TYPE_ID 900000000000011006 SNOMEDCT_US
CHEBI_ID CHEBI:6716 NCI
Chemical_Formula C24H34O4 NCI
Contributing_Source CTRP NCI
Contributing_Source FDA NCI
CTV3ID XU6ek SNOMEDCT_US
CTV3ID XUApz SNOMEDCT_US
DC 1 MSH
DEFINITION_STATUS_ID 900000000000074008 SNOMEDCT_US
DID 2422-8564 CSP
DX 19930101 MSH
EFFECTIVE_TIME 20020131 SNOMEDCT_US
FDA_UNII_CODE C2QI4IOI2G DRUGBANK
FDA_UNII_CODE C2QI4IOI2G NDFRT
HN 2010 (1973) MSH
LEVEL Ingredient NDFRT
LEVEL Salts/Esters USPMG
LT TRD MSH
LT TRD MTH
MDA 19920518 MSH
MESH_DEFINITION A synthetic progestin that is derived from 17-hydroxyprogesterone. It is a long-acting contraceptive that is effective both orally or by intramuscular injection and has also been used to treat breast and endometrial neoplasms. NDFRT
MESH_DUI D017258 NDFRT
MESH_NAME Medroxyprogesterone Acetate NDFRT
MESH_UI M0026185 NDFRT
MMR 20160531 MSH
MN D04.210.500.745.745.654.829.395.700.500 MSH
MODIFIER_ID 900000000000451002 SNOMEDCT_US
NDFRT_KIND DRUG_KIND NDFRT
NDFRT_KIND INGREDIENT_KIND NDFRT
NUI N0000007209 NDFRT
NUI N0000146186 NDFRT
PA D003271 MSH
PA D003272 MSH
PA D018931 MSH
PM 2010; see MEDROXYPROGESTERONE 17-ACETATE 1993-2009; MEDROXYPROGESTERONE 17-ACETATE was indexed under MEDROXYPROGESTERONE/analogs & derivatives 1978-1992, HYDROXYPROGESTERONES 1976-78, & MEDROXYPROGESTERONE 1973-75 MSH
RN 0 MSH
RN C2QI4IOI2G MSH
RR 1172-82-3 (cpd w/o isomeric designation) MSH
RR 2242-65-1 ((6 beta)-isomer) MSH
RR 560-12-3 ((6 alpha,17 alpha)-isomer) MSH
RR 71-58-9 (Medroxyprogesterone Acetate) MSH
RXAUI 1136878 RXNORM
RXAUI 1136888 RXNORM
RXAUI 1136892 RXNORM
RXAUI 1136901 RXNORM
RXAUI 2072205 RXNORM
RXAUI 2599730 RXNORM
RXAUI 2772933 RXNORM
RXAUI 3090882 RXNORM
RXAUI 3094465 RXNORM
RXAUI 3145780 RXNORM
RXAUI 3192009 RXNORM
RXAUI 3192010 RXNORM
RXAUI 3197082 RXNORM
RXAUI 3197083 RXNORM
RXAUI 3197085 RXNORM
RXAUI 3223235 RXNORM
RXAUI 3281929 RXNORM
RXAUI 3733572 RXNORM
RXAUI 710139 RXNORM
RXCUI 1000112 RXNORM
RXCUI 202886 RXNORM
RXCUI 202887 RXNORM
RXCUI 202888 RXNORM
RXCUI 202891 RXNORM
RXCUI 91770 RXNORM
RXN_ACTIVATED 01/28/2010 RXNORM
RXN_ACTIVATED 06/01/2016 RXNORM
RXN_BN_CARDINALITY single RXNORM
RXN_OBSOLETED 03/27/2013 RXNORM
RXN_OBSOLETED 06/28/2016 RXNORM
RXN_OBSOLETED 08/30/2007 RXNORM
SID APRD00627 DRUGBANK
SPL_SET_ID 04d23262-b778-4815-b56f-6ca6fef826c0 MTHSPL
SPL_SET_ID 0930a471-6ff1-43a1-b3ea-948ca3f99d06 MTHSPL
SPL_SET_ID 0ceb4952-5af3-4b80-b8b5-cea4e9a5486d MTHSPL
SPL_SET_ID 198d547d-c985-46bc-a66f-e3182a294cb5 MTHSPL
SPL_SET_ID 199cf13e-0859-4a73-9b45-e700d0cd1049 MTHSPL
SPL_SET_ID 20c0841f-740c-4d53-af55-938c4e5b09e5 MTHSPL
SPL_SET_ID 210a9132-8837-4b8a-829c-abfac2d6e3dc MTHSPL
SPL_SET_ID 2425f944-15d7-4b84-95a0-6538e843f130 MTHSPL
SPL_SET_ID 2627eb11-06bf-4a45-9172-094468e3ca07 MTHSPL
SPL_SET_ID 36ec4df9-298d-4b15-9386-7848d217a46c MTHSPL
SPL_SET_ID 37275fd0-eb24-40a4-a93f-b818bb98414e MTHSPL
SPL_SET_ID 390087a6-f3c3-4f0b-a930-79acf412f153 MTHSPL
SPL_SET_ID 428481bb-b7cf-4d76-b57d-0d6bfa2b6ac3 MTHSPL
SPL_SET_ID 437edd12-2c08-4df4-8cf7-64c47e4779ac MTHSPL
SPL_SET_ID 468a972c-cb14-47c3-bdf6-4f7b64509e5c MTHSPL
SPL_SET_ID 499051ac-ffaf-4db4-be45-a409bd54991f MTHSPL
SPL_SET_ID 51588bf9-ad2f-42d5-83a7-3431b6e891e3 MTHSPL
SPL_SET_ID 519f68cd-0751-4117-971b-f928dccdf5ba MTHSPL
SPL_SET_ID 571982db-e1ce-4c64-98c3-86f66f3e77b9 MTHSPL
SPL_SET_ID 67f65a9d-26d7-4b37-bff6-0caf3904dffd MTHSPL
SPL_SET_ID 701acf2c-fffe-451a-9b94-82d825e5a47c MTHSPL
SPL_SET_ID 788df737-e990-4b5e-accd-af13c3b2bf8b MTHSPL
SPL_SET_ID 816b9fd2-bc55-496b-846a-cabe7bbdecd6 MTHSPL
SPL_SET_ID 826f674c-8ef2-400a-bf0b-877320a8cb5d MTHSPL
SPL_SET_ID 8691e529-0681-47f4-bab8-c6873f1e1424 MTHSPL
SPL_SET_ID 8ad58c4b-c263-4562-92cd-b1f81f3e06b3 MTHSPL
SPL_SET_ID 91b3473d-b95b-4b7d-a1d4-3ff2cb75a9b9 MTHSPL
SPL_SET_ID 93b7c9e8-fa4a-4b6f-879f-d71fd251e349 MTHSPL
SPL_SET_ID 9eb200b0-db96-4a51-87ea-04db862978c8 MTHSPL
SPL_SET_ID a586be28-96af-4fed-a13f-9b94fd4c7405 MTHSPL
SPL_SET_ID b1a02aba-b398-46c4-b98b-7064797aaa4b MTHSPL
SPL_SET_ID b2573b85-a1d6-4ed8-a026-70ce8ed22ee1 MTHSPL
SPL_SET_ID b840f2b0-4c37-40f3-9c1c-cd906e3e1c5e MTHSPL
SPL_SET_ID bc417aba-2b32-4943-9031-ff2bf79c2dcb MTHSPL
SPL_SET_ID bdb89690-ced2-48e1-bb1a-e5eccfeda8eb MTHSPL
SPL_SET_ID bfdf335d-1cbb-4533-9fde-99a9c71f7504 MTHSPL
SPL_SET_ID c91f0af4-1411-4ab6-8b3c-b8dcfa56a9b7 MTHSPL
SPL_SET_ID cbf142f9-9af3-4d79-9343-0ab42d6dbe9f MTHSPL
SPL_SET_ID cd0bbdb2-754e-4e66-8f36-985b5819d642 MTHSPL
SPL_SET_ID cebb0059-0811-4289-8586-4e416ffed1ae MTHSPL
SPL_SET_ID d279981c-e9e4-4989-bafb-1e184a6d3dd2 MTHSPL
SPL_SET_ID d2c3d585-3b01-448b-a630-3ea9aa34bccb MTHSPL
SPL_SET_ID e1d5975a-e0e5-444d-bab0-3904c3f377c9 MTHSPL
SPL_SET_ID e5f5c46c-b8b7-4502-9d2b-8f12284d1a63 MTHSPL
SPL_SET_ID ec517411-6d3d-4cb1-a50e-f0818d03b0e4 MTHSPL
SPL_SET_ID fd0c0836-5d23-2183-da81-9dc7f4287052 MTHSPL
SPL_SET_ID fda3368b-4ce3-4972-885d-066858831ee0 MTHSPL
SUBSET_MEMBER 900000000000497000~MAPTARGET~XU6ek SNOMEDCT_US
SUBSET_MEMBER 900000000000497000~MAPTARGET~XUApz SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
TERMUI T051457 MSH
TERMUI T051458 MSH
TERMUI T051459 MSH
TERMUI T051460 MSH
TERMUI T051461 MSH
TERMUI T051462 MSH
TERMUI T051463 MSH
TERMUI T051464 MSH
TERMUI T051467 MSH
TERMUI T051468 MSH
TERMUI T051469 MSH
TERMUI T051470 MSH
TH FDA SRS (2014) MSH
TH NLM (1993) MSH
TH NLM (1998) MSH
TH POPLINE (1978) MSH
TH USP (19XX) MSH
TYPE_ID 900000000000003001 SNOMEDCT_US
TYPE_ID 900000000000013009 SNOMEDCT_US
VANDF_RECORD 50.416^423^Active/Master NDFRT
VUID 4017828 NDFRT

Additional Concept Data:  (none)

URL to Bookmark: https://ncim-stage.nci.nih.gov/ncimbrowser/ConceptReport.jsp?dictionary=NCI Metathesaurus&code=C0065864

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