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lycopene (CUI C0065331) Suggest changes to this concept
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Terms & Properties

Concept Unique Identifier (CUI): C0065331

NCI Thesaurus Code: C2226  (see NCI Thesaurus info)

Semantic Type: Pharmacologic Substance

Semantic Type: Organic Chemical

Semantic Type: Biologically Active Substance

NCIt Definition: A linear, unsaturated hydrocarbon carotenoid, the major red pigment in fruits such as tomatoes, pink grapefruit, apricots, red oranges, watermelon, rosehips, and guava. As a class, carotenoids are pigment compounds found in photosynthetic organisms (plants, algae, and some types of fungus), and are chemically characterized by a large polyene chain containing 35-40 carbon atoms; some carotenoid polyene chains are terminated by two 6-carbon rings. In animals, carotenoids such as lycopene may possess antioxidant properties which may retard aging and many degenerative diseases. As an essential nutrient, lycopene is required in the animal diet. (NCI04)

PDQ Definition: A linear, unsaturated hydrocarbon carotenoid, the major red pigment in fruits such as tomatoes, pink grapefruit, apricots, red oranges, watermelon, rosehips, and guava. As a class, carotenoids are pigment compounds found in photosynthetic organisms (plants, algae, and some types of fungus), and are chemically characterized by a large polyene chain containing 35-40 carbon atoms; some carotenoid polyene chains are terminated by two 6-carbon rings. In animals, carotenoids such as lycopene may possess antioxidant properties which may retard ageing and many degenerative diseases. As an essential nutrient, lycopene is required in the animal diet. Check for active clinical trials using this agent. (NCI Thesaurus)

NCI-GLOSS Definition: A red pigment found in tomatoes and some fruits. It is an antioxidant and may help prevent some types of cancer.

CRCH Definition: Carotenoid which is a terpene assembled from 8 isoprene units.

Synonyms & Abbreviations: (see Synonym Details)
2,6,10,14,19,23,27,31-octamethyldotriaconta-2,6,8,10,12,14,16,18,20,22,24,26,30-tridecaene
407322
502-65-8
all-trans-lycopene
LYC-O-MATO
Lycopene (substance)
lycopene [Chemical/Ingredient]
Lycopene
LYCO
psi,psi-carotene

External Source Codes: 
NCI Thesaurus Code C2226 (see NCI Thesaurus info)
CAS Registry Number 502-65-8 (see NLM ChemIDplus info)
FDA UNII Code SB0N2N0WV6
NSC Code 407322 (see NCI DTP info)
PDQ Closed Trial Search ID 37976
PDQ Open Trial Search ID 37976 (check for NCI PDQ open clinical trial info)

Other Properties: Property Definitions
Name Value Source
ACTIVE 1 SNOMEDCT_US
CASE_SIGNIFICANCE_ID 900000000000448009 SNOMEDCT_US
CHEBI_ID CHEBI:15948 NCI
Chemical_Formula C40H56 NCI
Contributing_Source CRCH NCI
Contributing_Source CTRP NCI
Contributing_Source FDA NCI
CTV3ID XUcbL SNOMEDCT_US
DATE_LAST_MODIFIED 2006-08-28 PDQ
DEFINITION_STATUS_ID 900000000000074008 SNOMEDCT_US
DID 2876-1992 CSP
EFFECTIVE_TIME 20050131 SNOMEDCT_US
FDA_UNII_CODE SB0N2N0WV6 NDFRT
FR 2061 MSH
HM D002338 MSH
INFOODS LYCPN NCI
LEVEL Ingredient NDFRT
LT TRD PDQ
MDA 19780101 MSH
MESH_DUI C015329 NDFRT
MESH_NAME lycopene NDFRT
MESH_UI M0064500 NDFRT
MMR 20121105 MSH
NCI_THESAURUS_CODE C2226 PDQ
NDFRT_KIND DRUG_KIND NDFRT
NDFRT_KIND INGREDIENT_KIND NDFRT
NUI N0000010541 NDFRT
NUI N0000148836 NDFRT
ORIG_STY Drug/agent PDQ
PA D000975 MSH
PA D011837 MSH
PA D016588 MSH
PID 10394 PDQ
RN SB0N2N0WV6 MSH
RR 13018-46-7 ((13-cis)-isomer) MSH
RR 2361-24-2 ((7-cis,7'-cis,9-cis,9'-cis)-isomer) MSH
RR 4418-71-7 ((cis)-isomer) MSH
RR 502-65-8 (lycopene) MSH
RXAUI 2072117 RXNORM
RXAUI 3187919 RXNORM
RXAUI 3187920 RXNORM
RXAUI 3261160 RXNORM
RXAUI 3261161 RXNORM
RXAUI 3262289 RXNORM
RXAUI 3520144 RXNORM
RXAUI 434295 RXNORM
RXAUI 5467386 RXNORM
RXAUI 6820724 RXNORM
RXCUI 29008 RXNORM
SC 1 MSH
SPL_SET_ID 0430bf68-ee36-4762-a245-ec280cb480a5 MTHSPL
SPL_SET_ID 0eaa3ab3-3905-4e03-95ce-dd1f41b58b4a MTHSPL
SPL_SET_ID 2c1a0cdc-de85-4108-aba9-72109eb4628a MTHSPL
SPL_SET_ID 2f5b946f-3751-4bcc-ace9-eb5041dd189e MTHSPL
SPL_SET_ID 41a0afe9-4c05-4f23-8893-07e374bc40f6 MTHSPL
SPL_SET_ID 5e9c03c7-136d-46b5-a16a-a3419a5bc079 MTHSPL
SPL_SET_ID 61f55a42-a2c3-4aa7-9935-69ada425b211 MTHSPL
SPL_SET_ID 8a995199-e1f0-492d-988f-78dfba5810a4 MTHSPL
SPL_SET_ID 8d28ec4c-429b-4a2d-8ed5-f572db6c330c MTHSPL
SPL_SET_ID 97118933-34e4-41ec-a20d-bdaca971c8a0 MTHSPL
SPL_SET_ID bf7698a5-915b-4510-82f5-69da719be29b MTHSPL
SPL_SET_ID c920c091-1eef-49e1-a697-eb5bf6aae145 MTHSPL
SPL_SET_ID cef96bec-57c1-4d8a-ad04-0007c128bfb4 MTHSPL
SPL_SET_ID d71b2d4b-a5db-4f69-a194-626466338efc MTHSPL
SPL_SET_ID e3acf62d-4acd-4490-86df-c6e1d3c909ce MTHSPL
SPL_SET_ID e4186262-a29c-40e9-8e21-1b32110321d3 MTHSPL
SPL_SET_ID e77a55ed-6e9d-4906-b0cf-d948fb414d13 MTHSPL
SPL_SET_ID e863e7ba-d1a7-416f-bb48-552ec3f3271e MTHSPL
SPL_SET_ID f208dd0c-721a-4bf6-a725-b55e0817735d MTHSPL
SPL_SET_ID f6db0332-58ed-4c82-a9dc-7fac621f1ac1 MTHSPL
SRC Biophysika 29(4):656;1977 MSH
SUBSET_MEMBER 900000000000497000~MAPTARGET~XUcbL SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
TERMUI T094503 MSH
TERMUI T442328 MSH
TERMUI T670925 MSH
TH FDA SRS (2013) MSH
TH NLM (1978) MSH
TH NLM (2001) MSH
TH NLM (2006) MSH
TYPE_ID 900000000000003001 SNOMEDCT_US
TYPE_ID 900000000000013009 SNOMEDCT_US
Unit mcg NCI
USDA_ID 337 NCI
VANDF_RECORD 50.416^4102^Active/Master NDFRT
VANDF_RECORD 50.6^3946^Active/Master NDFRT
VUID 4021425 NDFRT

Additional Concept Data:  (none)

URL to Bookmark: https://ncim-stage.nci.nih.gov/ncimbrowser/ConceptReport.jsp?dictionary=NCI Metathesaurus&code=C0065331

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