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epigallocatechin gallate (CUI C0059438) Suggest changes to this concept
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Terms & Properties

Concept Unique Identifier (CUI): C0059438

NCI Thesaurus Code: C1088  (see NCI Thesaurus info)

Semantic Type: Organic Chemical

Semantic Type: Pharmacologic Substance

NCIt Definition: A phenolic antioxidant found in a number of plants such as green and black tea. It inhibits cellular oxidation and prevents free radical damage to cells. It is under study as a potential cancer chemopreventive agent. (NCI)

PDQ Definition: A phenolic antioxidant found in a number of plants such as green and black tea. It inhibits cellular oxidation and prevents free radical damage to cells. It is under study as a potential cancer chemopreventive agent. Check for active clinical trials using this agent. (NCI Thesaurus)

CRCH Definition: A (-)-epicatechin-3-gallate with a hydroxyl group at C-5'.

Synonyms & Abbreviations: (see Synonym Details)
(-)-Epigallocatechin-3-Gallate
(2R-cis)-3,4-Dihydro-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-2H-1-benzopyran-3-yl 3,4,5-Trihydroxybenzoate
989-51-5
[(2R,3R)-2-(3,4,5-trihydroxyphenyl)-5,7-dihydroxy-chroman-3-yl] 3,4,5-trihydroxybenzoate
EGCG cpd
EGCG
epigallo-catechin gallate
Epigallocatechin Gallate
Epigallocatechin-3-Gallate
epigallocatechin-3-O-gallate
Epigallocatechin-Gallate
Epigallocatechingallate
Tea catechin

External Source Codes: 
NCI Thesaurus Code C1088 (see NCI Thesaurus info)
CAS Registry Number 989-51-5 (see NLM ChemIDplus info)
FDA UNII Code BQM438CTEL

Other Properties: Property Definitions
Name Value Source
CHEBI_ID CHEBI:4806 NCI
Chemical_Formula C22H18O11 NCI
Contributing_Source CRCH NCI
Contributing_Source FDA NCI
DATE_FIRST_PUBLISHED 2014-01-28 PDQ
DATE_LAST_MODIFIED 2014-01-28 PDQ
FR 3259 MSH
HM D002392/Q000031 MSH
II D011480/Q000031 MSH
II D011837/Q000031 MSH
II D014568/Q000031 MSH
MDA 19850717 MSH
MMR 20150312 MSH
NCI_THESAURUS_CODE C1088 PDQ
ORIG_STY Drug/agent PDQ
PA D000975 MSH
PA D016587 MSH
PA D016588 MSH
PA D018696 MSH
RN BQM438CTEL MSH
RR 27044-00-4 ((2R-cis)-isomer, unspecified gallate position) MSH
RR 989-51-5 (epigallocatechin gallate) MSH
RXAUI 2180560 RXNORM
RXAUI 4618280 RXNORM
RXAUI 5934349 RXNORM
RXCUI 24246 RXNORM
SC 1 MSH
SOS antimutagen in green tea (Camellia sinensis); a steroid 5alpha-reductase inhibitor; RN given refers to (2R-cis)-isomer; structure given in first source MSH
SPL_SET_ID 15c9f3c4-833a-4211-a0d0-31e754e7fb9f MTHSPL
SPL_SET_ID 2ba70ab3-a7ce-4096-ace4-09b78a83c792 MTHSPL
SPL_SET_ID 6374c55f-a4e8-452d-bffd-4ed19614f72a MTHSPL
SPL_SET_ID 68628b3a-2525-46a5-8d0e-253f45ace22e MTHSPL
SPL_SET_ID 7c161a17-cf82-4de3-8348-888c040df0f9 MTHSPL
SPL_SET_ID 8466215c-6afa-4fae-922c-97c5a7082054 MTHSPL
SPL_SET_ID 86693adc-70f8-4a6a-8935-f2564971e78a MTHSPL
SPL_SET_ID 96e4d5fe-f459-41f7-b446-342c12880223 MTHSPL
SPL_SET_ID acd8b31d-235c-4e8f-8688-f58acabc514a MTHSPL
SPL_SET_ID ce1156c7-110e-46c1-bbfe-19f12a72b71c MTHSPL
SPL_SET_ID d658fdc7-9dac-47bf-8e83-1433a29a6cf6 MTHSPL
SPL_SET_ID fb1693cb-c2c3-4c8d-8394-03601c67867a MTHSPL
SRC Mutat Res 1985;150(1-2):127 MSH
TERMUI T000876737 MSH
TERMUI T162656 MSH
TERMUI T162657 MSH
TERMUI T162658 MSH
TERMUI T463363 MSH
TH FDA SRS (2013) MSH
TH NLM (1985) MSH
TH NLM (2001) MSH
TH NLM (2015) MSH
Unit mg NCI

Additional Concept Data:  (none)

URL to Bookmark: https://ncim-stage.nci.nih.gov/ncimbrowser/ConceptReport.jsp?dictionary=NCI Metathesaurus&code=C0059438

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