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Wernicke Encephalopathy (CUI C0043121) Suggest changes to this concept
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Terms & Properties

Concept Unique Identifier (CUI): C0043121

Semantic Type: Disease or Syndrome

RADLEX Definition: An acute neurological disorder characterized by the triad of ophthalmoplegia, ataxia, and disturbances of mental activity or consciousness. Eye movement abnormalities include nystagmus, external rectus palsies, and reduced conjugate gaze. thiamine deficiency and chronic alcoholism are associated conditions. Pathologic features include periventricular petechial hemorrhages and neuropil breakdown in the diencephalon and brainstem. Chronic thiamine deficiency may lead to korsakoff syndrome. (Adams et al., Principles of Neurology, 6th ed, pp1139-42; Davis & Robertson, Textbook of Neuropathology, 2nd ed, pp452-3) [MeSH]

MSH Definition: An acute neurological disorder characterized by the triad of ophthalmoplegia, ataxia, and disturbances of mental activity or consciousness. Eye movement abnormalities include nystagmus, external rectus palsies, and reduced conjugate gaze. THIAMINE DEFICIENCY and chronic ALCOHOLISM are associated conditions. Pathologic features include periventricular petechial hemorrhages and neuropil breakdown in the diencephalon and brainstem. Chronic thiamine deficiency may lead to KORSAKOFF SYNDROME. (Adams et al., Principles of Neurology, 6th ed, pp1139-42; Davis & Robertson, Textbook of Neuropathology, 2nd ed, pp452-3)

Synonyms & Abbreviations: (see Synonym Details)
Beriberi, Cerebral
Cerebral Beriberi
ENCEPH GAYET WERNICKE
ENCEPH WERNICKES
ENCEPH WERNICKE
Encephalopathies, Wernicke
Encephalopathy, Gayet Wernicke
Encephalopathy, Gayet-Wernicke
Encephalopathy, Wernicke's
Encephalopathy, Wernickes
ENCEPHALOPATHY, WERNICKE
Gayet Wernicke Encephalopathy
GAYET WERNICKE ENCEPH
Gayet-Wernicke Encephalopathy
GAYET-WERNICKE SYNDROME
Wernicke Disease
WERNICKE DIS
Wernicke Encephalopathies
Wernicke Encephalopathy [Disease/Finding]
WERNICKE ENCEPHALOPATHY SYNDROME
Wernicke encephalopathy
WERNICKE ENCEPH
Wernicke Enzephalopathie
WERNICKE POLIOENCEPH SUPERIOR HEMORRHAGIC
Wernicke Polioencephalitis, Superior Hemorrhagic
Wernicke Superior Hemorrhagic Polioencephalitis
WERNICKE SUPERIOR HEMORRHAGIC POLIOENCEPH
Wernicke Syndrome
Wernicke's disease (disorder)
Wernicke's disease
Wernicke's encephalopathy
Wernicke's Polioencephalitis, Superior Hemorrhagic
Wernicke's Superior Hemorrhagic Polioencephalitis
Wernicke's syndrome
WERNICKES DIS
WERNICKES ENCEPH
WERNICKES SUPERIOR HEMORRHAGIC POLIOENCEPH

External Source Codes:  (none)

Other Properties: Property Definitions
Name Value Source
ACTIVE 1 SNOMEDCT_US
AN DF: WERNICKE ENCEPH MSH
AQL BL CF CI CL CN CO DG DH DI DT EC EH EM EN EP ET GE HI IM ME MI MO NU PA PC PP PS PX RH RT SU TH UR VE VI MSH
CASE_SIGNIFICANCE_ID 900000000000017005 SNOMEDCT_US
CTV3ID X0053 SNOMEDCT_US
DATE_CREATED 2013-01-09T00:04:00 GARD
DATE_LAST_MODIFIED 2013-01-09T00:04:00 GARD
DC 1 MSH
DEFINITION_STATUS_ID 900000000000074008 SNOMEDCT_US
DISEASE_IDENTIFIER_ID 4311 GARD
DX 19700101 MSH
EFFECTIVE_TIME 20020131 SNOMEDCT_US
HN 2000(1964) MSH
HN Changed descriptor 2000; through 1999 use "Wernicke encephalopathy." AOD
IAN DEFAULT ICD10
IDENTIFIER_TYPE_ID 1 GARD
IS_ACTIVE true GARD
MDA 19990101 MSH
MESH_DEFINITION An acute neurological disorder characterized by the triad of ophthalmoplegia, ataxia, and disturbances of mental activity or consciousness. Eye movement abnormalities include nystagmus, external rectus palsies, and reduced conjugate gaze. THIAMINE DEFICIENCY and chronic ALCOHOLISM are associated conditions. Pathologic features include periventricular petechial hemorrhages and neuropil breakdown in the diencephalon and brainstem. Chronic thiamine deficiency may lead to KORSAKOFF SYNDROME. (Adams et al., Principles of Neurology, 6th ed, pp1139-42; Davis & Robertson, Textbook of Neuropathology, 2nd ed, pp452-3) NDFRT
MESH_DUI D014899 NDFRT
MESH_NAME Wernicke Encephalopathy NDFRT
MESH_UI M0022921 NDFRT
MMR 20130708 MSH
MN C10.228.140.163.960 MSH
MN C18.452.132.960 MSH
MN C18.654.521.500.133.699.827.822 MSH
MN C25.775.100.625 MSH
MN F03.900.100.875 MSH
NDFRT_KIND DISEASE_KIND NDFRT
NUI N0000003160 NDFRT
ORDER_NO 04427 ICD10CM
PM 2000; see WERNICKE'S ENCEPHALOPATHY 1970-1999, see VITAMIN B DEFICIENCY 1963-1969 MSH
PRIMARY_PATH 10047911$10014624$10014623$10029205$Wernicke's encephalopathy$Encephalopathies toxic and metabolic$Encephalopathies$Nervous system disorders MDR
PRIMARY_SOC 10029205 MDR
PT_IN_VERSION 10.0 MDR
PT_IN_VERSION 10.1 MDR
PT_IN_VERSION 11.0 MDR
PT_IN_VERSION 11.1 MDR
PT_IN_VERSION 12.0 MDR
PT_IN_VERSION 12.1 MDR
PT_IN_VERSION 13.0 MDR
PT_IN_VERSION 13.1 MDR
PT_IN_VERSION 14.0 MDR
PT_IN_VERSION 14.1 MDR
PT_IN_VERSION 15.0 MDR
PT_IN_VERSION 15.1 MDR
PT_IN_VERSION 16.0 MDR
PT_IN_VERSION 16.1 MDR
PT_IN_VERSION 17.0 MDR
PT_IN_VERSION 17.1 MDR
PT_IN_VERSION 18.0 MDR
PT_IN_VERSION 18.1 MDR
PT_IN_VERSION 19.0 MDR
PT_IN_VERSION 19.1 MDR
PT_IN_VERSION 8.0 MDR
PT_IN_VERSION 8.1 MDR
PT_IN_VERSION 9.0 MDR
PT_IN_VERSION 9.1 MDR
RXAUI 3117446 RXNORM
RXAUI 3153874 RXNORM
RXAUI 3153910 RXNORM
RXAUI 3153911 RXNORM
RXAUI 3164983 RXNORM
RXAUI 3256400 RXNORM
RXAUI 3256403 RXNORM
RXAUI 3256404 RXNORM
RXAUI 3256407 RXNORM
RXAUI 3256408 RXNORM
RXAUI 3256409 RXNORM
RXAUI 3256410 RXNORM
RXAUI 3256412 RXNORM
RXAUI 3256415 RXNORM
RXAUI 3256416 RXNORM
RXAUI 3256417 RXNORM
RXCUI 1022848 RXNORM
SNOMED_CID 21007002 NDFRT
SNOMEDID D6-C1150 SNOMEDCT_US
SOS An acute, life-threatening, neurological syndrome consisting of confusion, apathy, dullness, a dreamy delirium, palsies of the ocular muscles and of gaze, nystagmus and disturbances in equilibrium, and ataxia. Its most common cause in industrialized countries is thiamine deficiency associated with alcoholism. If not treated immediately with thiamine, the patient is likely to die or progress into an amnesic syndrome. AOD
SUBSET_MEMBER 447562003~CORRELATIONID~447561005 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPADVICE~ALWAYS E51.2 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPCATEGORYID~447637006 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPGROUP~1 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPPRIORITY~1 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPRULE~TRUE SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPTARGET~E51.2 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~CORRELATIONID~447561005 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~ALWAYS E51.2 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPCATEGORYID~447637006 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPGROUP~1 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~1 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~TRUE SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~E51.2 SNOMEDCT_US
SUBSET_MEMBER 900000000000497000~MAPTARGET~X0053 SNOMEDCT_US
SUBSET_MEMBER 900000000000498005~MAPTARGET~D6-C1150 SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
TERMUI T043488 MSH
TERMUI T365821 MSH
TERMUI T370898 MSH
TERMUI T370899 MSH
TERMUI T370900 MSH
TERMUI T370901 MSH
TERMUI T370902 MSH
TERMUI T370903 MSH
TERMUI T370904 MSH
TERMUI T370905 MSH
TERMUI T370906 MSH
TERMUI T370907 MSH
TERMUI T370908 MSH
TERMUI T370909 MSH
TERMUI T372613 MSH
TH NLM (1964) MSH
TH NLM (2000) MSH
TH ORD (2010) MSH
TYPE_ID 900000000000003001 SNOMEDCT_US
TYPE_ID 900000000000013009 SNOMEDCT_US

Additional Concept Data:  (none)

URL to Bookmark: https://ncim-stage.nci.nih.gov/ncimbrowser/ConceptReport.jsp?dictionary=NCI Metathesaurus&code=C0043121

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