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Vitamin B12 Deficiency (CUI C0042847) Suggest changes to this concept
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Terms & Properties

Concept Unique Identifier (CUI): C0042847

NCI Thesaurus Code: C131684  (see NCI Thesaurus info)

Semantic Type: Disease or Syndrome

NCIt Definition: Low serum levels of vitamin B12 (cobalamin) due to poor intestinal absorption, decreased dietary intake, or increased physiologic requirement.

NICHD Definition: Low serum levels of vitamin B12 (cobalamin) due to poor intestinal absorption, decreased dietary intake, or increased physiologic requirement.

CSP Definition: condition due to a deficiency of vitamin B12.

MSH Definition: A nutritional condition produced by a deficiency of VITAMIN B 12 in the diet, characterized by megaloblastic anemia. Since vitamin B 12 is not present in plants, humans have obtained their supply from animal products, from multivitamin supplements in the form of pills, and as additives to food preparations. A wide variety of neuropsychiatric abnormalities is also seen in vitamin B 12 deficiency and appears to be due to an undefined defect involving myelin synthesis. (From Cecil Textbook of Medicine, 19th ed, p848)

Synonyms & Abbreviations: (see Synonym Details)
Cobalamin deficiency (disorder)
Cobalamin deficiency
CYANOCOBALAMIN DEFICIENCY
DEFIC VITAMIN B 12
DEFIC VITAMIN B12
Deficiencies, Vitamin B12
Deficiency of vitamin B12
Deficiency of vitamin B<sub>12</sub>
Deficiency of vitamin B>12<
Deficiency, Vitamin B 12
Deficiency, Vitamin B12
Hypocobalaminemia
Vitamin B 12 Deficiency [Disease/Finding]
VITAMIN B 12 DEFICIENCY
VITAMIN B 12 DEFIC
VITAMIN B A 12 DEFICIENCY
Vitamin B12 Deficiencies
VITAMIN B12 DEFICIENCY
VITAMIN B12 DEFIC

External Source Codes: 
NCI Thesaurus Code C131684 (see NCI Thesaurus info)

Other Properties: Property Definitions
Name Value Source
ACTIVE 1 SNOMEDCT_US
AN coord IM with specific B 12 vitamin /defic (IM); DF: VITAMIN B 12 DEFIC MSH
AQL BL CF CI CL CN CO DG DH DI DT EC EH EM EN EP ET GE HI IM ME MI MO NU PA PC PP PS PX RH RT SU TH UR VE VI MSH
CASE_SIGNIFICANCE_ID 900000000000020002 SNOMEDCT_US
CASE_SIGNIFICANCE_ID 900000000000448009 SNOMEDCT_US
CHARACTERISTIC_TYPE_ID 900000000000011006 SNOMEDCT_US
Contributing_Source NICHD NCI
CTV3ID C2621 SNOMEDCT_US
DATE_CREATED 2010-12-17T06:00:43Z HPO
DC 1 MSH
DEFINITION_STATUS_ID 900000000000074008 SNOMEDCT_US
DID 2116-7456 CSP
DX 19660101 MSH
EFFECTIVE_TIME 20020131 SNOMEDCT_US
MDA 19990101 MSH
MESH_DEFINITION A nutritional condition produced by a deficiency of VITAMIN B 12 in the diet, characterized by megaloblastic anemia. Since vitamin B 12 is not present in plants, humans have obtained their supply from animal products, from multivitamin supplements in the form of pills, and as additives to food preparations. A wide variety of neuropsychiatric abnormalities is also seen in vitamin B 12 deficiency and appears to be due to an undefined defect involving myelin synthesis. (From Cecil Textbook of Medicine, 19th ed, p848) NDFRT
MESH_DUI D014806 NDFRT
MESH_NAME Vitamin B 12 Deficiency NDFRT
MESH_UI M0022796 NDFRT
MMR 20030709 MSH
MN C18.654.521.500.133.699.923 MSH
MODIFIER_ID 900000000000451002 SNOMEDCT_US
NDFRT_KIND DISEASE_KIND NDFRT
NICHD_Hierarchy_Term Vitamin B12 Deficiency NCI
NUI N0000003133 NDFRT
PRIMARY_PATH 10047609$10047842$10047635$10027433$Vitamin B12 deficiency$Water soluble vitamin deficiencies$Vitamin related disorders$Metabolism and nutrition disorders MDR
PRIMARY_SOC 10027433 MDR
PT_IN_VERSION 10.0 MDR
PT_IN_VERSION 10.1 MDR
PT_IN_VERSION 11.0 MDR
PT_IN_VERSION 11.1 MDR
PT_IN_VERSION 12.0 MDR
PT_IN_VERSION 12.1 MDR
PT_IN_VERSION 13.0 MDR
PT_IN_VERSION 13.1 MDR
PT_IN_VERSION 14.0 MDR
PT_IN_VERSION 14.1 MDR
PT_IN_VERSION 15.0 MDR
PT_IN_VERSION 15.1 MDR
PT_IN_VERSION 16.0 MDR
PT_IN_VERSION 16.1 MDR
PT_IN_VERSION 17.0 MDR
PT_IN_VERSION 17.1 MDR
PT_IN_VERSION 18.0 MDR
PT_IN_VERSION 18.1 MDR
PT_IN_VERSION 19.0 MDR
PT_IN_VERSION 19.1 MDR
PT_IN_VERSION 20.0 MDR
PT_IN_VERSION 20.1 MDR
PT_IN_VERSION 8.0 MDR
PT_IN_VERSION 8.1 MDR
PT_IN_VERSION 9.0 MDR
PT_IN_VERSION 9.1 MDR
RXAUI 3144950 RXNORM
RXAUI 3144952 RXNORM
RXAUI 3255685 RXNORM
RXAUI 3255686 RXNORM
RXAUI 3255713 RXNORM
RXCUI 1022421 RXNORM
SNOMED_CID 190634004 NDFRT
SUBSET_MEMBER 447562003~CORRELATIONID~447561005 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPADVICE~ALWAYS E53.8 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPCATEGORYID~447637006 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPGROUP~1 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPPRIORITY~1 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPRULE~TRUE SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPTARGET~E53.8 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~CORRELATIONID~447561005 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~ALWAYS E53.8 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~IF FETAL OR NEONATAL VITAMIN B12 DEFICIENCY DUE TO MATERNAL VITAMIN B12 DEFICIENCY CHOOSE P00.4 | CONSIDER ADDITIONAL CODE TO IDENTIFY SPECIFIC CONDITION OR DISEASE | MAP OF SOURCE CONCEPT IS CONTEXT DEPENDENT SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~IF FETAL OR NEONATAL VITAMIN B12 DEFICIENCY DUE TO MATERNAL VITAMIN B12 DEFICIENCY CHOOSE P74.8 | MAP OF SOURCE CONCEPT IS CONTEXT DEPENDENT SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~MAP SOURCE CONCEPT CANNOT BE CLASSIFIED WITH AVAILABLE DATA SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPCATEGORYID~447637006 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPCATEGORYID~447638001 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPCATEGORYID~447639009 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPGROUP~1 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPGROUP~2 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~1 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~2 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~IFA 722597005 | Fetal or neonatal vitamin B12 deficiency due to maternal vitamin B12 deficiency | SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~OTHERWISE TRUE SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~E53.8 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~P00.4 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~P74.8 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~ SNOMEDCT_US
SUBSET_MEMBER 900000000000497000~MAPTARGET~C2621 SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
TERMUI T043292 MSH
TERMUI T043293 MSH
TERMUI T043294 MSH
TERMUI T043295 MSH
TH NLM (1966) MSH
TH NLM (1992) MSH
TH UNK (19XX) MSH
TYPE_ID 900000000000003001 SNOMEDCT_US
TYPE_ID 900000000000013009 SNOMEDCT_US

Additional Concept Data:  (none)

URL to Bookmark: https://ncim-stage.nci.nih.gov/ncimbrowser/ConceptReport.jsp?dictionary=NCI Metathesaurus&code=C0042847

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