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Tyrosine (CUI C0041485) Suggest changes to this concept
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Terms & Properties

Concept Unique Identifier (CUI): C0041485

NCI Thesaurus Code: C915  (see NCI Thesaurus info)

Semantic Type: Biologically Active Substance

Semantic Type: Pharmacologic Substance

Semantic Type: Amino Acid, Peptide, or Protein

NCIt Definition: The levorotatory isomer of the aromatic amino acid tyrosine. L-tyrosine is a naturally occurring tyrosine and is synthesized in vivo from L-phenylalanine. It is considered a non-essential amino acid; however, in patients with phenylketonuria who lack phenylalanine hydroxylase and cannot convert phenylalanine into tyrosine, it is considered an essential nutrient. In vivo, tyrosine plays a role in protein synthesis and serves as a precursor for the synthesis of catecholamines, thyroxine, and melanin.

CRCH Definition: Amino acid with side chain -CH2-C6H4OH.

CSP Definition: amino acid, p-hydroxyphenylalanine, found in most proteins, synthesized metabolically from phenylalanine; a precursor of thyroid hormones, catecholamines, and melanin.

MSH Definition: A non-essential amino acid. In animals it is synthesized from PHENYLALANINE. It is also the precursor of EPINEPHRINE; THYROID HORMONES; and melanin.

NPO Definition: An alpha-aminoacid with chemical formula NH2-CH(Cc1ccc(O)cc1)-C(OH)=OH.

Synonyms & Abbreviations: (see Synonym Details)
(-)-alpha-amino-P-Hydroxyhydrocinnamic acid
(-)-α-amino-p-hydroxyhydrocinnamic acid
(2S)-2-amino-3-(4-hydroxyphenyl)propanoic acid
(S)-(-)-Tyrosine
(S)-2-Amino-3-(4-hydroxy-phenyl)propanoic acid
(S)-2-Amino-3-(p-hydroxyphenyl)propionic acid
(S)-3-(p-Hydroxyphenyl)alanine
(S)-alpha-amino-4-Hydroxybenzenepropanoic acid
(S)-Tyrosine
(S)-α-amino-4-hydroxybenzenepropanoic acid
4-hydroxy-L-phenylalanine
L Tyrosine
L-Phenylalanine, 4-hydroxy-
L-Tyrosine
L-Tyrosin
para Tyrosine
para-Tyrosine
Try
Tyrosine (product)
Tyrosine (substance)
Tyrosine [Chemical/Ingredient]
TYROSINE, (L)
Tyrosine, L isomer
Tyrosine, L-isomer
tyrosine
Tyr
Y

External Source Codes: 
NCI Thesaurus Code C915 (see NCI Thesaurus info)
CAS Registry Number 60-18-4 (see NLM ChemIDplus info)
FDA UNII Code 42HK56048U
NSC Code 9973 (see NCI DTP info)

Other Properties: Property Definitions
Name Value Source
ACTIVE 1 SNOMEDCT_US
AN /blood: consider also TYROSINEMIAS MSH
AQL AA AD AE AG AI AN BI BL CF CH CL CS CT DE DF EC GE HI IM IP ME PD PH PK PO RE SD SE ST TO TU UR MSH
AUTHORITY Rosse MD FMA
CASE_SIGNIFICANCE_ID 900000000000020002 SNOMEDCT_US
CASE_SIGNIFICANCE_ID 900000000000448009 SNOMEDCT_US
CHARACTERISTIC_TYPE_ID 900000000000011006 SNOMEDCT_US
CHEBI_ID CHEBI:17895 NCI
Chemical_Formula C9H11NO3 NCI
CODE NPO_906 NPO
Contributing_Source CRCH NCI
Contributing_Source CTRP NCI
Contributing_Source FDA NCI
CTV3ID X807a SNOMEDCT_US
CTV3ID XUdm8 SNOMEDCT_US
DB_XR_ID CHEBI:18186 NPO
DC 1 MSH
DEFINITION_STATUS_ID 900000000000074008 SNOMEDCT_US
DID 0777-8387 CSP
DX 19660101 MSH
EFFECTIVE_TIME 20020131 SNOMEDCT_US
EFFECTIVE_TIME 20060131 SNOMEDCT_US
FDA_UNII_CODE 42HK56048U DRUGBANK
FDA_UNII_CODE 42HK56048U NDFRT
INFOODS TYR_G NCI
LEVEL Ingredient NDFRT
MDA 19990101 MSH
MESH_DEFINITION A non-essential amino acid. In animals it is synthesized from PHENYLALANINE. It is also the precursor of EPINEPHRINE; THYROID HORMONES; and melanin. NDFRT
MESH_DUI D014443 NDFRT
MESH_NAME Tyrosine NDFRT
MESH_UI M0022203 NDFRT
MMR 20130708 MSH
MN D12.125.072.050.875 MSH
MODIFIER_ID 900000000000451002 SNOMEDCT_US
NDFRT_KIND DRUG_KIND NDFRT
NDFRT_KIND INGREDIENT_KIND NDFRT
NUI N0000006152 NDFRT
NUI N0000146989 NDFRT
RDF_ID CHEBI_18186 NPO
RN 42HK56048U MSH
RR 55520-40-6 (Tyrosine) MSH
RR 60-18-4 (L-isomer) MSH
RXAUI 2075101 RXNORM
RXAUI 2598178 RXNORM
RXAUI 3185379 RXNORM
RXAUI 3247103 RXNORM
RXAUI 3247104 RXNORM
RXAUI 3251944 RXNORM
RXAUI 3251984 RXNORM
RXAUI 3251988 RXNORM
RXAUI 3262044 RXNORM
RXAUI 3294069 RXNORM
RXAUI 349826 RXNORM
RXAUI 6798224 RXNORM
RXCUI 10962 RXNORM
SID NUTR00059 DRUGBANK
SPL_SET_ID 00a58408-97c6-4e08-9595-da4b8653b956 MTHSPL
SPL_SET_ID 022d4bd6-f1b6-4906-b38b-8fcd08551e4a MTHSPL
SPL_SET_ID 02597da7-70bc-44f5-50a5-d67934125b7f MTHSPL
SPL_SET_ID 0569d5d5-70df-46d7-954a-fe00542a7191 MTHSPL
SPL_SET_ID 05d5761b-738f-46fa-833c-97901d1164de MTHSPL
SPL_SET_ID 0fbd48e4-222b-474d-ba1e-a9eec23e40e8 MTHSPL
SPL_SET_ID 1082fb92-5986-4960-8d60-508e07ba9f78 MTHSPL
SPL_SET_ID 10f47475-ebff-4002-9f24-bb6b5681bac3 MTHSPL
SPL_SET_ID 13213a12-0a9b-4179-8da5-ae7e5ef4c3f7 MTHSPL
SPL_SET_ID 1a518385-14dd-4546-86b5-79d7d1191087 MTHSPL
SPL_SET_ID 1d88fbe0-eb97-4964-8a78-88940064f8f0 MTHSPL
SPL_SET_ID 21c9be9e-5545-480b-b2ad-928806045d95 MTHSPL
SPL_SET_ID 246c4712-5bbb-463a-2eac-5074d32d9b40 MTHSPL
SPL_SET_ID 28e0dfa0-9cda-436b-89bf-043d7baf2efe MTHSPL
SPL_SET_ID 29f3ce30-0083-409f-e054-00144ff8d46c MTHSPL
SPL_SET_ID 2a2c7bf4-6640-4324-e054-00144ff8d46c MTHSPL
SPL_SET_ID 2a2dd2ea-a9dd-70b1-e054-00144ff88e88 MTHSPL
SPL_SET_ID 2a44bd5b-4b60-6b9f-e054-00144ff8d46c MTHSPL
SPL_SET_ID 2a54e87f-ab46-6829-e054-00144ff88e88 MTHSPL
SPL_SET_ID 2fd28d08-ee4e-498d-907a-de311874c66b MTHSPL
SPL_SET_ID 32b9ad34-c7f2-4f30-b2f2-29f3e1b2647e MTHSPL
SPL_SET_ID 3bc3437c-5597-447f-5695-36dbdbef88b2 MTHSPL
SPL_SET_ID 401040da-f219-4cea-a141-b28687841536 MTHSPL
SPL_SET_ID 49c82c3a-eaa3-46ec-870a-0b8f5492b1f2 MTHSPL
SPL_SET_ID 49e4b0c1-d513-4f54-9844-1b2b707110fb MTHSPL
SPL_SET_ID 4c294bea-5a61-4756-af3c-17ed30f2c0d8 MTHSPL
SPL_SET_ID 51d5d0ce-5329-4ee9-868a-c826a8f29c2d MTHSPL
SPL_SET_ID 54168b09-09b7-4952-925f-af85a7157709 MTHSPL
SPL_SET_ID 546f8eac-3d64-40d5-9d5e-5a5dcf71b110 MTHSPL
SPL_SET_ID 563036ee-90e0-4cef-2c80-d6776ed93591 MTHSPL
SPL_SET_ID 5d10aa9b-e2e8-43aa-bfce-c3a8122cd8a4 MTHSPL
SPL_SET_ID 61754b89-92b7-4219-bd2d-6437e0901424 MTHSPL
SPL_SET_ID 61958bbf-653b-450e-b95b-2a5ac203fc9c MTHSPL
SPL_SET_ID 63f7ac0f-51d7-4e9e-bc54-aee51183bbaa MTHSPL
SPL_SET_ID 65ffc962-7538-41ea-9afb-4af5fbce4c5b MTHSPL
SPL_SET_ID 66f53ef8-03e7-48da-9365-02832e08b08f MTHSPL
SPL_SET_ID 71359f14-0f8f-4e90-af1d-426e8c21bd61 MTHSPL
SPL_SET_ID 71a81955-0f76-4481-beac-cdff5e512e4a MTHSPL
SPL_SET_ID 7eaebb0f-3f5b-4569-ab96-84f9d9104187 MTHSPL
SPL_SET_ID 81db8c8f-df4e-45ad-8f8c-ee3aaf47fd95 MTHSPL
SPL_SET_ID 8469d6fb-d6ef-476f-8cc3-0905192de0a8 MTHSPL
SPL_SET_ID 8543b5be-0f43-4891-9e56-d7c39fe839b5 MTHSPL
SPL_SET_ID 8c2a04f8-877b-47f4-98d1-ef0046dad4f2 MTHSPL
SPL_SET_ID 974d14c6-74b0-43b3-8218-13c94b730dc9 MTHSPL
SPL_SET_ID 98ac8494-54c8-47f4-afb8-b7e46f1c0e8a MTHSPL
SPL_SET_ID 9a04fe02-16af-4dd1-8e12-cc9e64f9bfce MTHSPL
SPL_SET_ID 9afdcc3e-0d06-47f4-86ca-40da48b2b02b MTHSPL
SPL_SET_ID 9c4be0f2-fe10-471a-8192-8a896518dbc5 MTHSPL
SPL_SET_ID 9c573fc8-ba7a-4f05-b4d7-179e8ad3e2ad MTHSPL
SPL_SET_ID a0aedcb7-8bf6-4e2b-a85a-dd8f1411dcfc MTHSPL
SPL_SET_ID accf470e-f8a0-4d3f-a4a6-33f3f912d536 MTHSPL
SPL_SET_ID ae5ae89b-2b93-4c88-f2bb-c554aeb8b12e MTHSPL
SPL_SET_ID afeb4837-a759-4484-a76e-e04611c459e7 MTHSPL
SPL_SET_ID b40f6e83-0b88-406b-880d-ba475a588ff1 MTHSPL
SPL_SET_ID b95b7647-d6c0-4470-fba0-680256661dd2 MTHSPL
SPL_SET_ID bbbd8cca-f746-4d68-bcef-f44b4ac44b97 MTHSPL
SPL_SET_ID bd67e4ac-be0a-4bc8-9f00-a0d8b17b9c81 MTHSPL
SPL_SET_ID c2eb5522-8572-45f4-869d-42f9fd251bb6 MTHSPL
SPL_SET_ID ca3c681c-5e5b-34d0-5917-549529afa65d MTHSPL
SPL_SET_ID cc2ace81-5881-43f1-ba94-41b674adc2fc MTHSPL
SPL_SET_ID ce0939de-1b69-4a4f-9641-e10794d9f17c MTHSPL
SPL_SET_ID d7a12d00-b8a6-4532-acef-d6d4b6edf0dd MTHSPL
SPL_SET_ID dccff103-8695-400c-a15d-cc2fd078760a MTHSPL
SPL_SET_ID dd664735-5125-4229-96b0-12466f5c8020 MTHSPL
SPL_SET_ID e1864a26-e8a3-4c9d-a468-ea020fdc30e1 MTHSPL
SPL_SET_ID e2adc2d6-3d41-435c-ba3f-5f50dcf034e0 MTHSPL
SPL_SET_ID e6153e0e-4936-4399-a2a8-11432a1ac50d MTHSPL
SPL_SET_ID e649dc50-a3ce-4151-f698-788b6d5c83d0 MTHSPL
SPL_SET_ID e9a6280a-ad94-4209-8d12-40af3d5681b2 MTHSPL
SPL_SET_ID f0c3cafa-8985-4dac-9be1-a92454a4ef6e MTHSPL
SPL_SET_ID f3182470-1965-4e20-dbaf-e3506f893ea5 MTHSPL
SPL_SET_ID f3c9743b-9c5d-49e9-a7e7-ecb6560ffa84 MTHSPL
SPL_SET_ID f452b457-5ca1-4fdc-a319-eadbc04e953a MTHSPL
SPL_SET_ID f6c9bc0f-a7e1-4cd6-a03a-d681d3adae7f MTHSPL
SPL_SET_ID f8bed4b0-d838-4e93-bdd1-c0b038edb32a MTHSPL
SPL_SET_ID f9b7bf26-e83f-4923-af17-cb4fc5d87a2b MTHSPL
SPL_SET_ID fa9ed512-97dc-44a2-b32d-86ca8c240532 MTHSPL
SPL_SET_ID fd0b42d6-6733-4525-6283-715ee5a466a9 MTHSPL
SUBSET_MEMBER 900000000000497000~MAPTARGET~X807a SNOMEDCT_US
SUBSET_MEMBER 900000000000497000~MAPTARGET~XUdm8 SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
TERMUI T042248 MSH
TERMUI T042249 MSH
TERMUI T359772 MSH
TERMUI T363943 MSH
TH FDA SRS (2014) MSH
TH INN (19XX) MSH
TH NLM (1966) MSH
TH NLM (1999) MSH
TH NLM (2000) MSH
TH UNK (19XX) MSH
TH USAN (19XX) MSH
TH USP (19XX) MSH
TYPE_ID 900000000000003001 SNOMEDCT_US
TYPE_ID 900000000000013009 SNOMEDCT_US
Unit g NCI
USDA_ID 509 NCI
VANDF_RECORD 50.416^1279^Active/Master NDFRT
VANDF_RECORD 50.6^2579^Active/Master NDFRT
VUID 4018678 NDFRT

Additional Concept Data:  (none)

URL to Bookmark: https://ncim-stage.nci.nih.gov/ncimbrowser/ConceptReport.jsp?dictionary=NCI Metathesaurus&code=C0041485

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