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Tyramine (CUI C0041479) Suggest changes to this concept
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Terms & Properties

Concept Unique Identifier (CUI): C0041479

Semantic Type: Biologically Active Substance

Semantic Type: Organic Chemical

Semantic Type: Pharmacologic Substance

MSH Definition: An indirect sympathomimetic that occurs naturally in cheese and other foods. Tyramine does not directly activate adrenergic receptors, but it can serve as a substrate for adrenergic uptake systems and MONOAMINE OXIDASE to prolong the actions of adrenergic transmitters. It also provokes transmitter release from adrenergic terminals and may be a neurotransmitter in some invertebrate nervous systems.

CSP Definition: decarboxylation product of tyrosine; structurally similar to epinephrine with weak adrenergic activity.

Synonyms & Abbreviations: (see Synonym Details)
4 Hydroxyphenethylamine
4-(2-Aminoethyl)phenol
4-Hydroxyphenethylamine
Phenol, 4-(2-aminoethyl)-
Tyramine (substance)
Tyramine [Chemical/Ingredient]
tyramine

External Source Codes:  (none)

Other Properties: Property Definitions
Name Value Source
ACTIVE 1 SNOMEDCT_US
AQL AA AD AE AG AI AN BI BL CF CH CL CS CT EC HI IM IP ME PD PH PK PO RE SD ST TO TU UR MSH
CASE_SIGNIFICANCE_ID 900000000000020002 SNOMEDCT_US
CHARACTERISTIC_TYPE_ID 900000000000011006 SNOMEDCT_US
CTV3ID Ub09b SNOMEDCT_US
DC 1 MSH
DEFINITION_STATUS_ID 900000000000074008 SNOMEDCT_US
DID 2262-3494 CSP
DX 19660101 MSH
EFFECTIVE_TIME 20020131 SNOMEDCT_US
FDA_UNII_CODE X8ZC7V0OX3 NDFRT
LEVEL Ingredient NDFRT
MDA 19990101 MSH
MESH_DEFINITION An indirect sympathomimetic. Tyramine does not directly activate adrenergic receptors, but it can serve as a substrate for adrenergic uptake systems and monoamine oxidase so it prolongs the actions of adrenergic transmitters. It also provokes transmitter release from adrenergic terminals. Tyramine may be a neurotransmitter in some invertebrate nervous systems. NDFRT
MESH_DUI D014439 NDFRT
MESH_NAME Tyramine NDFRT
MESH_UI M0022194 NDFRT
MMR 20160701 MSH
MN D02.092.211.215.811 MSH
MODIFIER_ID 900000000000451002 SNOMEDCT_US
MODULE_ID 731000124108 SNOMEDCT_US
MODULE_NAME US National Library of Medicine maintained module SNOMEDCT_US
NDFRT_KIND DRUG_KIND NDFRT
NDFRT_KIND INGREDIENT_KIND NDFRT
NUI N0000010547 NDFRT
NUI N0000148848 NDFRT
PA D013566 MSH
PA D018759 MSH
RN X8ZC7V0OX3 MSH
RR 51-67-2 (Tyramine) MSH
RXAUI 2075098 RXNORM
RXAUI 3093536 RXNORM
RXAUI 3219775 RXNORM
RXAUI 3247094 RXNORM
RXAUI 3247095 RXNORM
RXAUI 3251932 RXNORM
RXAUI 3251934 RXNORM
RXAUI 349706 RXNORM
RXAUI 3750631 RXNORM
RXAUI 4667479 RXNORM
RXCUI 10958 RXNORM
RXN_ACTIVATED 01/28/2010 RXNORM
RXN_OBSOLETED 08/30/2007 RXNORM
SNOMEDID F-61630 SNOMEDCT_US
SPL_SET_ID 0012578b-66ff-49a8-8415-693c68ab9c16 MTHSPL
SPL_SET_ID 02e3d6d8-ea32-4cfa-bd9b-0d6e72bb4552 MTHSPL
SPL_SET_ID 0e44d728-e216-4910-8202-05041ad15d69 MTHSPL
SPL_SET_ID 160afc8d-b485-41ac-97ad-96f567ace387 MTHSPL
SPL_SET_ID 19aa6ca2-66e9-42e7-91e4-93220da84a08 MTHSPL
SPL_SET_ID 350f76f7-a6de-48b9-a09a-847ba4041180 MTHSPL
SPL_SET_ID 37936067-b318-4f94-a9f0-8d68e5311e09 MTHSPL
SPL_SET_ID 3af34476-26df-8ecd-2198-40b6ee5708b0 MTHSPL
SPL_SET_ID 4533d8c9-b35c-4753-bb72-ba4fffd0f1a9 MTHSPL
SPL_SET_ID 54e8f581-9286-4784-bd48-68f8a2e5eba4 MTHSPL
SPL_SET_ID 57c8ec91-5103-4e6f-a678-efa4d55145ae MTHSPL
SPL_SET_ID 59a111c0-b728-4f33-8528-4cb09ecf5ae3 MTHSPL
SPL_SET_ID 6e77a40c-6c9d-44ed-8a62-1b3a508a69dc MTHSPL
SPL_SET_ID 70c21d52-b73a-4d44-a08a-15b852d9307c MTHSPL
SPL_SET_ID 74bdd5ad-0f93-4f2e-87a1-960d68458314 MTHSPL
SPL_SET_ID 81ffe61c-2b0c-4a56-b02b-8463300e218e MTHSPL
SPL_SET_ID 83a0738f-3e0b-45ea-a752-395a38043b2b MTHSPL
SPL_SET_ID 8ee54281-1ef9-4d02-b384-a20de092ad26 MTHSPL
SPL_SET_ID daeddbf8-5a68-4998-aad9-d182b14aab31 MTHSPL
SPL_SET_ID dd6b7ad0-0dca-40a0-9b38-5856f1893281 MTHSPL
SPL_SET_ID eea6de39-1c18-4935-86e9-d7e4252eaec7 MTHSPL
SUBSET_MEMBER 900000000000497000~MAPTARGET~Ub09b SNOMEDCT_US
SUBSET_MEMBER 900000000000498005~MAPTARGET~F-61630 SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
TERMUI T000901346 MSH
TERMUI T042227 MSH
TERMUI T042228 MSH
TH FDA SRS (2014) MSH
TH NLM (1966) MSH
TH NLM (1995) MSH
TH NLM (2017) MSH
TYPE_ID 900000000000003001 SNOMEDCT_US
TYPE_ID 900000000000013009 SNOMEDCT_US
VANDF_RECORD 50.416^4141^Active/Master NDFRT
VUID 4021457 NDFRT

Additional Concept Data:  (none)

URL to Bookmark: https://ncim-stage.nci.nih.gov/ncimbrowser/ConceptReport.jsp?dictionary=NCI Metathesaurus&code=C0041479

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