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African Trypanosomiasis (CUI C0041228) Suggest changes to this concept
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Terms & Properties

Concept Unique Identifier (CUI): C0041228

NCI Thesaurus Code: C84541  (see NCI Thesaurus info)

Semantic Type: Disease or Syndrome

NCIt Definition: A parasitic disorder caused by protozoa of the Trypanosoma brucei species. It is transmitted by flies and is endemic in various regions of Sub-Saharan Africa. Signs and symptoms include fever, joint pain, headache, and significant swelling of the lymph nodes. If left untreated, the parasitic infection causes anemia, heart, kidney, and endocrine failure, and neurologic damage. Subsequently patients develop confusion, disruption of the sleep cycle, and mental deterioration. The infection may lead to coma and death.

NICHD Definition: A protozoan infection that is caused by Trypanosoma brucei, which is transmitted by tsetse flies; it is characterized by fever, joint pain, headache, and lymphadenopathy, and it may progress to multi-organ involvement.

MSH Definition: A disease endemic among people and animals in Central Africa. It is caused by various species of trypanosomes, particularly T. gambiense and T. rhodesiense. Its second host is the TSETSE FLY. Involvement of the central nervous system produces "African sleeping sickness." Nagana is a rapidly fatal trypanosomiasis of horses and other animals.

Synonyms & Abbreviations: (see Synonym Details)
African Sleeping Sicknesses
African sleeping sickness
African trypanosoma NOS
African Trypanosomiases
African trypanosomiasis (disorder)
African trypanosomiasis, unspecified
African trypanosomiasis
MALADIE DU SOMMEIL
SCHLAFKRANKHEIT
Sickness, African Sleeping
Sicknesses, African Sleeping
Sleeping sickness NOS
SLEEPING SICKNESS, AFRICAN
Sleeping Sicknesses, African
Sleeping Sickness
Trypanosomiases, African
Trypanosomiasis, African [Disease/Finding]
TRYPANOSOMIASIS, AFRICAN
Trypanosomiasis, Human East-African

External Source Codes: 
NCI Thesaurus Code C84541 (see NCI Thesaurus info)

Other Properties: Property Definitions
Name Value Source
ACTIVE 1 SNOMEDCT_US
AN for trypanosomiasis in tropical Africa caused by any species of Trypanosoma; coordinate with NEGLECTED DISEASES if pertinent; coordinate IM with TRYPANOSOMA BRUCEI GAMBIENSE (IM) for Gambian trypanosomiasis; entry term NAGANA: coordinate TRYPANOSOMIASIS, AFRICAN /vet (IM) with specific Trypanosoma species (IM) + animal disease term (IM) + specific animal (IM or NIM) + check tag ANIMALS; specify geographic term pertinent MSH
AQL BL CF CI CL CN CO DG DH DI DT EC EH EM EN EP ET GE HI IM ME MI MO NU PA PC PP PS PX RH RT SU TH TM UR VE VI MSH
CASE_SIGNIFICANCE_ID 900000000000017005 SNOMEDCT_US
CASE_SIGNIFICANCE_ID 900000000000020002 SNOMEDCT_US
Contributing_Source NICHD NCI
CTV3ID X70PB SNOMEDCT_US
DATE_CREATED 2013-01-09T00:04:00 GARD
DATE_LAST_MODIFIED 2013-01-09T00:04:00 GARD
DC 1 MSH
DEFINITION_STATUS_ID 900000000000073002 SNOMEDCT_US
DID 2214-6161 CSP
DISEASE_IDENTIFIER_ID 5931 GARD
DX 19600101 MSH
EFFECTIVE_TIME 20020731 SNOMEDCT_US
HAS_GARD_PAGE true GARD
HN NAGANA was heading 1991-94; was see under TRYPANOSOMIASIS, AFRICAN 1973-90; was see under TRYPANOSOMIASIS, BOVINE 1968-mid 72 MSH
IAN DEFAULT ICD10
ICE Sleeping sickness NOS ICD9CM
IDENTIFIER_TYPE_ID 1 GARD
INCLUSION_TERM Sleeping sickness NOS ICD10
INCLUSION_TERM Trypanosomiasis NOS, in places where African trypanosomiasis is prevalent ICD10
IS_ACTIVE true GARD
IS_RARE true GARD
IS_SPANISH false GARD
MDA 19990101 MSH
MESH_DEFINITION A disease endemic among people and animals in Central Africa. It is caused by various species of trypanosomes, particularly T. gambiense and T. rhodesiense. Its second host is the TSETSE FLY. Involvement of the central nervous system produces "African sleeping sickness." Nagana is a rapidly fatal trypanosomiasis of horses and other animals. NDFRT
MESH_DUI D014353 NDFRT
MESH_NAME Trypanosomiasis, African NDFRT
MESH_UI M0022074 NDFRT
MMR 20121204 MSH
MN C03.752.300.900.719 MSH
NDFRT_KIND DISEASE_KIND NDFRT
NICHD_Hierarchy_Term African Trypanosomiasis NCI
NUI N0000003026 NDFRT
OL use TRYPANOSOMIASIS, AFRICAN to search NAGANA 1975-94; use TRYPANOSOMIASIS, AFRICAN/VE 1972-74; use TRYPANOSOMIASIS, BOVINE 1968-72 MSH
ORDER_NO 01045 ICD10CM
ORDER_NO 01048 ICD10CM
PM NAGANA was heading 1991-94; was see under TRYPANOSOMIASIS, AFRICAN 1973-90; was see under TRYPANOSOMIASIS, BOVINE 1968-mid 72 MSH
PRIMARY_PATH 10001461$10044708$10037072$10021881$African trypanosomiasis$Trypanosomal infections$Protozoal infectious disorders$Infections and infestations MDR
PRIMARY_SOC 10021881 MDR
PT_IN_VERSION 10.0 MDR
PT_IN_VERSION 10.1 MDR
PT_IN_VERSION 11.0 MDR
PT_IN_VERSION 11.1 MDR
PT_IN_VERSION 12.0 MDR
PT_IN_VERSION 12.1 MDR
PT_IN_VERSION 13.0 MDR
PT_IN_VERSION 13.1 MDR
PT_IN_VERSION 14.0 MDR
PT_IN_VERSION 14.1 MDR
PT_IN_VERSION 15.0 MDR
PT_IN_VERSION 15.1 MDR
PT_IN_VERSION 16.0 MDR
PT_IN_VERSION 16.1 MDR
PT_IN_VERSION 17.0 MDR
PT_IN_VERSION 17.1 MDR
PT_IN_VERSION 18.0 MDR
PT_IN_VERSION 18.1 MDR
PT_IN_VERSION 19.0 MDR
PT_IN_VERSION 19.1 MDR
PT_IN_VERSION 8.0 MDR
PT_IN_VERSION 8.1 MDR
PT_IN_VERSION 9.0 MDR
PT_IN_VERSION 9.1 MDR
RARE_DISEASE_URL http://rarediseases.info.nih.gov/gard/7826/trypanosomiasis-human-east-african/resources/1 GARD
RXAUI 3107079 RXNORM
RXAUI 3107083 RXNORM
RXAUI 3251034 RXNORM
RXAUI 3251035 RXNORM
RXCUI 1022679 RXNORM
SNOMED_CID 27031003 NDFRT
SNOMEDID DE-55030 SNOMEDCT_US
SUBSET_MEMBER 447562003~CORRELATIONID~447561005 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPADVICE~ALWAYS B56.0 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPCATEGORYID~447637006 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPGROUP~1 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPPRIORITY~1 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPRULE~TRUE SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPTARGET~B56.0 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~CORRELATIONID~447561005 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~ALWAYS B56.9 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~IF INFECTION CAUSED BY TRYPANOSOMA GAMBIENSE CHOOSE B56.0 | MAP OF SOURCE CONCEPT IS CONTEXT DEPENDENT SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~IF INFECTION CAUSED BY TRYPANOSOMA RHODESIENSE CHOOSE B56.1 | MAP OF SOURCE CONCEPT IS CONTEXT DEPENDENT SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPCATEGORYID~447637006 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPCATEGORYID~447639009 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPGROUP~1 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~1 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~2 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~3 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~IFA 42872003 | Infection caused by Trypanosoma rhodesiense (disorder) | SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~IFA 75809006 | Infection caused by Trypanosoma gambiense (disorder) | SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~OTHERWISE TRUE SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~B56.0 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~B56.1 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~B56.9 SNOMEDCT_US
SUBSET_MEMBER 900000000000497000~MAPTARGET~X70PB SNOMEDCT_US
SUBSET_MEMBER 900000000000498005~MAPTARGET~DE-55030 SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
TERMUI T041993 MSH
TERMUI T041994 MSH
TERMUI T041995 MSH
TH NLM (1966) MSH
TH NLM (1995) MSH
TH ORD (2010) MSH
TYPE_ID 900000000000003001 SNOMEDCT_US
TYPE_ID 900000000000013009 SNOMEDCT_US

Additional Concept Data:  (none)

URL to Bookmark: https://ncim-stage.nci.nih.gov/ncimbrowser/ConceptReport.jsp?dictionary=NCI Metathesaurus&code=C0041228

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