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Tromethamine (CUI C0041175) Suggest changes to this concept
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Terms & Properties

Concept Unique Identifier (CUI): C0041175

NCI Thesaurus Code: C47775  (see NCI Thesaurus info)

Semantic Type: Indicator, Reagent, or Diagnostic Aid

Semantic Type: Organic Chemical

Semantic Type: Pharmacologic Substance

MSH Definition: An organic amine proton acceptor. It is used in the synthesis of surface-active agents and pharmaceuticals; as an emulsifying agent for cosmetic creams and lotions, mineral oil and paraffin wax emulsions, as a biological buffer, and used as an alkalizer. (From Merck, 11th ed; Martindale, The Extra Pharmacopoeia, 30th ed, p1424)

Synonyms & Abbreviations: (see Synonym Details)
1,3-Propanediol, 2-amino-2-(hydroxymethyl)-
Abbott Brand of Trometamol
Aminotrimethylolmethane
Product containing trometamol (medicinal product)
Product containing trometamol
Product containing tromethamine
Tham brand of tromethamine
THAM
Tri(hydroxymethyl)aminomethane
Tris Buffer
Tris(hydroxymethyl)aminomethane
Tris(hydroxymethyly)amino Methane
Tris-base
Trisamine
Tris
Trometamol (substance)
Trometamol
Tromethamine (TRIS)
Tromethamine [Chemical/Ingredient]
Tromethamine

External Source Codes: 
NCI Thesaurus Code C47775 (see NCI Thesaurus info)
CAS Registry Number 77-86-1 (see NLM ChemIDplus info)
FDA UNII Code 023C2WHX2V
NSC Code 6365 (see NCI DTP info)
NSC Code 65434 (see NCI DTP info)

Other Properties: Property Definitions
Name Value Source
ACTIVE 1 SNOMEDCT_US
AQL AA AD AE AG AI AN BL CF CH CL CS CT EC HI IM IP ME PD PK PO RE SD ST TO TU UR MSH
CASE_SIGNIFICANCE_ID 900000000000448009 SNOMEDCT_US
CHARACTERISTIC_TYPE_ID 900000000000011006 SNOMEDCT_US
CHEBI_ID CHEBI:9754 NCI
Chemical_Formula C4H11NO3 NCI
CODE NPO_1918 NPO
Contributing_Source FDA NCI
CTV3ID XUaAh SNOMEDCT_US
CTV3ID XUH6i SNOMEDCT_US
DC 1 MSH
DEFINITION_STATUS_ID 900000000000074008 SNOMEDCT_US
DX 19650101 MSH
EFFECTIVE_TIME 20020131 SNOMEDCT_US
EFFECTIVE_TIME 20040131 SNOMEDCT_US
FDA_UNII_CODE 023C2WHX2V DRUGBANK
FDA_UNII_CODE 023C2WHX2V NDFRT
HN 65 MSH
LEVEL Ingredient NDFRT
LT TRD MSH
LT TRD MTH
MDA 19990101 MSH
MESH_DEFINITION An organic amine proton acceptor. It is used in the synthesis of surface-active agents and pharmaceuticals; as an emulsifying agent for cosmetic creams and lotions, mineral oil and paraffin wax emulsions, as a biological buffer, and used as an alkalizer. (From Merck, 11th ed; Martindale, The Extra Pharmacopoeia, 30th ed, p1424) NDFRT
MESH_DUI D014325 NDFRT
MESH_NAME Tromethamine NDFRT
MESH_UI M0022030 NDFRT
MMR 20160701 MSH
MN D02.033.455.706.900 MSH
MODIFIER_ID 900000000000451002 SNOMEDCT_US
NDFRT_KIND DRUG_KIND NDFRT
NDFRT_KIND INGREDIENT_KIND NDFRT
NUI N0000006938 NDFRT
NUI N0000146434 NDFRT
PA D002021 MSH
PA D005079 MSH
PM 65 MSH
RDF_ID NPO_1918 NPO
RN 023C2WHX2V MSH
RR 77-86-1 (Tromethamine) MSH
RXAUI 1641024 RXNORM
RXAUI 2075024 RXNORM
RXAUI 3052902 RXNORM
RXAUI 3091221 RXNORM
RXAUI 3104317 RXNORM
RXAUI 3246913 RXNORM
RXAUI 3246914 RXNORM
RXAUI 3247908 RXNORM
RXAUI 3250540 RXNORM
RXAUI 3250895 RXNORM
RXAUI 3250897 RXNORM
RXAUI 3250900 RXNORM
RXAUI 3250943 RXNORM
RXAUI 3250944 RXNORM
RXAUI 3250945 RXNORM
RXAUI 346648 RXNORM
RXAUI 4237554 RXNORM
RXAUI 4237555 RXNORM
RXAUI 4239643 RXNORM
RXCUI 10865 RXNORM
RXCUI 393491 RXNORM
RXN_BN_CARDINALITY single RXNORM
SID EXPT03072 DRUGBANK
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SPL_SET_ID CF288AD5-D4E7-4B0B-BFD0-41C5327E6984 MTHSPL
SPL_SET_ID cf4d0a21-8b7d-44ae-9867-a3d77ae2c983 MTHSPL
SPL_SET_ID d02f2dcc-b699-4441-a86c-ce386675eb7a MTHSPL
SPL_SET_ID d2510515-c8c1-4086-a4a7-f1caadfaa6b7 MTHSPL
SPL_SET_ID d3bebc1c-f032-402a-bbc9-aff024276ed1 MTHSPL
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SPL_SET_ID d55e85de-486d-44a4-ae72-0f2114be96f4 MTHSPL
SPL_SET_ID d96a7883-d160-40a1-bdbd-2e8d7877cd18 MTHSPL
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SPL_SET_ID e6937dda-afe6-4f65-83e8-1a5a6ba15390 MTHSPL
SPL_SET_ID e6d1a245-db4c-4668-bb7e-1f4e44e687b5 MTHSPL
SPL_SET_ID e7af6a7a-8046-4fb4-9979-4ec4230b23aa MTHSPL
SPL_SET_ID e7b2c0fb-f7bd-45ee-be27-ff2110cff583 MTHSPL
SPL_SET_ID e8b76200-c0aa-491b-aad7-e22d2f68496f MTHSPL
SPL_SET_ID e9d87b8c-7695-4c0f-8e81-000dedb5f66d MTHSPL
SPL_SET_ID ea443790-f0d1-47e3-b753-a118f67f9cfe MTHSPL
SPL_SET_ID ed4ca733-dbff-4ee7-b6c5-1ccad7a0717b MTHSPL
SPL_SET_ID eee15ebe-d349-4497-acef-6abe7a8247fb MTHSPL
SPL_SET_ID f2ba0c81-ceb0-11e0-9572-0800200c9a66 MTHSPL
SPL_SET_ID f306f837-05f6-48c3-9248-8de7267f1fe6 MTHSPL
SPL_SET_ID f5252ac5-3c22-4c6f-a6d0-caf3282fc33f MTHSPL
SPL_SET_ID f64f75d4-1a02-4463-bcc0-a923dadd1b19 MTHSPL
SPL_SET_ID f7dce32b-c942-4933-b2a0-e4f78e78b6f7 MTHSPL
SPL_SET_ID f85c2f05-3471-4658-8887-7126a87c168d MTHSPL
SPL_SET_ID f8b0646e-7d2a-4bed-9ed7-25253ec500d8 MTHSPL
SPL_SET_ID f9e9d558-064c-4b86-8d96-2f8a678c89f9 MTHSPL
SPL_SET_ID fa4ac98b-eb2b-4027-9548-3f3d9c9d6534 MTHSPL
SPL_SET_ID fbd37cc7-374d-4946-9872-fca701b36ec2 MTHSPL
SPL_SET_ID ff348f48-352b-4f4c-8260-f412ef884213 MTHSPL
SPL_SET_ID ff80bdf2-ed0c-4914-bf13-39997cba1d3a MTHSPL
SUBSET_MEMBER 900000000000497000~MAPTARGET~XUaAh SNOMEDCT_US
SUBSET_MEMBER 900000000000497000~MAPTARGET~XUH6i SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
TERMUI T041927 MSH
TERMUI T041928 MSH
TERMUI T041929 MSH
TERMUI T041930 MSH
TERMUI T041931 MSH
TERMUI T041933 MSH
TERMUI T669705 MSH
TH AU MSH
TH BAN (19XX) MSH
TH FDA SRS (2014) MSH
TH INN (19XX) MSH
TH UNK (19XX) MSH
TH USAN (1962) MSH
TH USP (19XX) MSH
TH US MSH
TYPE_ID 900000000000003001 SNOMEDCT_US
TYPE_ID 900000000000013009 SNOMEDCT_US
VANDF_RECORD 50.416^693^Active/Master NDFRT
VANDF_RECORD 50.6^1014^Active/Master NDFRT
VUID 4018096 NDFRT

Additional Concept Data:  (none)

URL to Bookmark: https://ncim-stage.nci.nih.gov/ncimbrowser/ConceptReport.jsp?dictionary=NCI Metathesaurus&code=C0041175

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