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liothyronine (CUI C0041014) Suggest changes to this concept
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Terms & Properties

Concept Unique Identifier (CUI): C0041014

NCI Thesaurus Code: C2303  (see NCI Thesaurus info)

Semantic Type: Amino Acid, Peptide, or Protein

Semantic Type: Pharmacologic Substance

Semantic Type: Hormone

NCIt Definition: A thyroid hormone containing 3 iodine atoms generally synthesized from levothyroxine, and has greater biological activity.

NCI-GLOSS Definition: A thyroid hormone.

CSP Definition: one of the thyroid hormones; an organic iodine containing compound secreted in small amounts by the thyroid gland; most circulating triiodothyroinine is produced by the deiodination of thyroxine in the peripheral tissues.

MSH Definition: A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.

Synonyms & Abbreviations: (see Synonym Details)
3,3',5-triiodo-L-thyronine
3,5,3'-Triiodo-L-thyronine
3,5,3'-Triiodothyronine
3,5,3'TRIIODOTHYRONINE
4-(4-Hydroxy-3-iodophenoxy)-3,5-diiodo-L-phenylalanine
L-3,5,3'-Triiodothyronine
L-T3
L-Tyrosine, O-(4-hydroxy-3-iodophenyl)-3,5-diiodo-
Liothyronine
Liothyroninum
Liotironina
O-(4-hydroxy-3-iodophenyl)-3,5-diiodo-L-tyrosine
T AAA THYROID HORMONE 003
T-3
T3 Thyroid Hormone
T3
Thyroid Hormone, T3
Triiodothyronine [Chemical/Ingredient]
triiodothyronine

External Source Codes: 
NCI Thesaurus Code C2303 (see NCI Thesaurus info)
CAS Registry Number 6893-02-3 (see NLM ChemIDplus info)
CAS Registry Number 5714-08-9 (see NLM ChemIDplus info)
NSC Code 46046 (see NCI DTP info)

Other Properties: Property Definitions
Name Value Source
AQL AA AD AE AG AI AN BI BL CF CH CL CS CT DE DF EC GE HI IM IP ME PD PH PK PO RE SD SE ST TO TU UR MSH
CHEBI_ID CHEBI:11684 NCI
CHEBI_ID CHEBI:18258 NCI
Contributing_Source CTRP NCI
DC 1 MSH
DID 2930-7465 CSP
DX 19600101 MSH
FDA_UNII_CODE 06LU7C9H1V DRUGBANK
FX D011988 MSH
HN LIOTHYRONINE was heading 1963-66 MSH
MDA 19990101 MSH
MESH_DEFINITION A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3. NDFRT
MESH_DUI D014284 NDFRT
MESH_NAME Triiodothyronine NDFRT
MESH_UI M0021977 NDFRT
MMR 20130708 MSH
MN D06.472.931.740.385 MSH
MN D12.125.072.050.767.741.894 MSH
NDFRT_KIND INGREDIENT_KIND NDFRT
NUI N0000006165 NDFRT
OL use TRIIODOTHYRONINE to search LIOTHYRONINE 1966 MSH
PM LIOTHYRONINE was heading 1963-66 MSH
RN 06LU7C9H1V MSH
RR 6893-02-3 (Triiodothyronine) MSH
RXAUI 3185386 RXNORM
RXAUI 3189657 RXNORM
RXAUI 3243431 RXNORM
RXAUI 3250768 RXNORM
RXAUI 3250769 RXNORM
RXCUI 10814 RXNORM
SID APRD01074 DRUGBANK
TERMUI T041812 MSH
TERMUI T041813 MSH
TERMUI T429465 MSH
TH FDA SRS (2014) MSH
TH INN (19XX) MSH
TH NLM (1966) MSH
TH NLM (2002) MSH
TH UNK (19XX) MSH

Additional Concept Data:  (none)

URL to Bookmark: https://ncim-stage.nci.nih.gov/ncimbrowser/ConceptReport.jsp?dictionary=NCI Metathesaurus&code=C0041014

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