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Thiourea (CUI C0039958) Suggest changes to this concept
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Terms & Properties

Concept Unique Identifier (CUI): C0039958

NCI Thesaurus Code: C44455  (see NCI Thesaurus info)

Semantic Type: Organic Chemical

Semantic Type: Indicator, Reagent, or Diagnostic Aid

NCIt Definition: A white crystalline solid, both naturally occurring and synthetic, that is soluble in water, ammonium thiocyanate solution and ethanol. In the past, it was used as a photographic toning agent, a component of hair preparations and a dry cleaning agent. Currently, it is only used in animal glue liquefiers and silver tarnish removers. When heated to decomposition, thiourea emits toxic fumes of nitrogen oxides and sulfur oxides. Long-term exposure of humans to thiourea may cause bone marrow damage, resulting in reduced levels of red blood cells, white blood cells and/or platelets. It is reasonably anticipated to be a human carcinogen. (NCI05)

CSP Definition: (NH2)2C=S; precursor and metabolite of 2-thiouracil, used for similar purposes.

MSH Definition: A photographic fixative used also in the manufacture of resins. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance may reasonably be anticipated to be a carcinogen (Merck Index, 9th ed). Many of its derivatives are ANTITHYROID AGENTS and/or FREE RADICAL SCAVENGERS.

Synonyms & Abbreviations: (see Synonym Details)
2-Thiourea
Isothiourea
Pseudothiourea
Sulfourea
Thiocarbamide
Thiourea (product)
Thiourea (substance)
Thiourea [Chemical/Ingredient]
thiourea
THU
USAF EK-497

External Source Codes: 
NCI Thesaurus Code C44455 (see NCI Thesaurus info)
CAS Registry Number 62-56-6 (see NLM ChemIDplus info)
FDA UNII Code GYV9AM2QAG
NSC Code 5033 (see NCI DTP info)

Other Properties: Property Definitions
Name Value Source
ACTIVE 1 SNOMEDCT_US
AN a thyroid antag MSH
AQL AA AD AE AG AI AN BL CF CH CL CS CT EC HI IM IP ME PD PK PO RE SD ST TO TU UR MSH
CASE_SIGNIFICANCE_ID 900000000000448009 SNOMEDCT_US
CHARACTERISTIC_TYPE_ID 900000000000011006 SNOMEDCT_US
CHEBI_ID CHEBI:36946 NCI
Chemical_Formula CH4N2S NCI
Contributing_Source FDA NCI
CTV3ID X79JQ SNOMEDCT_US
CTV3ID XUbkp SNOMEDCT_US
DC 1 MSH
DEFINITION_STATUS_ID 900000000000074008 SNOMEDCT_US
DID 2913-2642 CSP
DX 19660101 MSH
EFFECTIVE_TIME 20020131 SNOMEDCT_US
EFFECTIVE_TIME 20040731 SNOMEDCT_US
FDA_UNII_CODE GYV9AM2QAG NDFRT
LEVEL Ingredient NDFRT
MDA 19990101 MSH
MESH_DEFINITION A photographic fixative used also in the manufacture of resins. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance may reasonably be anticipated to be a carcinogen (Merck Index, 9th ed). Many of its derivatives are ANTITHYROID AGENTS and/or FREE RADICAL SCAVENGERS. NDFRT
MESH_DUI D013890 NDFRT
MESH_NAME Thiourea NDFRT
MESH_UI M0021386 NDFRT
MMR 20130708 MSH
MN D02.886.904 MSH
MN D02.948.898 MSH
MODIFIER_ID 900000000000451002 SNOMEDCT_US
NDFRT_KIND DRUG_KIND NDFRT
NDFRT_KIND INGREDIENT_KIND NDFRT
NUI N0000166458 NDFRT
NUI N0000171813 NDFRT
PA D007202 MSH
RN GYV9AM2QAG MSH
RR 62-56-6 (Thiourea) MSH
RXAUI 2602774 RXNORM
RXAUI 3245112 RXNORM
RXAUI 3245113 RXNORM
RXAUI 3248226 RXNORM
RXAUI 3248227 RXNORM
RXCUI 10513 RXNORM
SUBSET_MEMBER 900000000000497000~MAPTARGET~X79JQ SNOMEDCT_US
SUBSET_MEMBER 900000000000497000~MAPTARGET~XUbkp SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
TERMUI T040748 MSH
TH FDA SRS (2014) MSH
TH NLM (1966) MSH
TYPE_ID 900000000000003001 SNOMEDCT_US
TYPE_ID 900000000000013009 SNOMEDCT_US
VANDF_RECORD 50.416^4346^Active/Master NDFRT
VUID 4025288 NDFRT

Additional Concept Data:  (none)

URL to Bookmark: https://ncim-stage.nci.nih.gov/ncimbrowser/ConceptReport.jsp?dictionary=NCI Metathesaurus&code=C0039958

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