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| Terms & Properties |
Concept Unique Identifier (CUI): C0039663
NCI Thesaurus Code: C867 (see NCI Thesaurus info)
Semantic Type: Organic Chemical
Semantic Type: Pharmacologic Substance
NCIt Definition: An isomer of tetrahydrocannabinol (THC) that is the main and most active isomer found in the cannabis sativa L. plant, with potential anti-emetic, analgesic and appetite stimulating activities. Upon administration, dronabinol, also called delta-9-THC, targets and binds to cannabinoid receptors (CBRs) located in the central nervous system (CNS). Dronabinol acts directly on the appetite and vomiting control centers in the brain to stimulate appetite and prevent emesis. In addition, this agent induces analgesia. Urine levels may be used as a marker to determine the exposure to certain preparations containing parts of the cannabis plant, such as marijuana.
MSH Definition: A psychoactive compound extracted from the resin of Cannabis sativa (marihuana, hashish). The isomer delta-9-tetrahydrocannabinol (THC) is considered the most active form, producing characteristic mood and perceptual changes associated with this compound.
PDQ Definition: An isomer of tetrahydrocannabinol (THC) that is the main and most active isomer found in the cannabis sativa L. plant, with potential anti-emetic, analgesic and appetite stimulating activities. Upon administration, dronabinol, also called delta-9-THC, targets and binds to cannabinoid receptors (CBRs) located in the central nervous system (CNS). Dronabinol acts directly on the appetite and vomiting control centers in the brain to stimulate appetite and prevent emesis. In addition, this agent induces analgesia. Urine levels may be used as a marker to determine the exposure to certain preparations containing parts of the cannabis plant, such as marijuana. Check for active clinical trials using this agent. (NCI Thesaurus)
NCI-GLOSS Definition: A synthetic pill form of delta-9-tetrahydrocannabinol (THC), an active ingredient in marijuana that is used to treat nausea and vomiting associated with cancer chemotherapy.
Synonyms & Abbreviations: (see Synonym Details)
| (-)-.DELTA.9-Tetrahydrocannabinol |
| (-)-delta9-trans-Tetrahydrocannabinol |
| 1-trans-delta-9-Tetrahydrocannabinol |
| 3-Pentyl-6,6,9-trimethyl-6a,7,8,10a-tetrahydro-6H-dibenzo(b,D)pyran-1-ol |
| 6,6,9-Trimethyl-3-pentyl-6a,7,8,10a-tetrahydro-6H-benzo[c]chromen-1-ol |
| 6H-Dibenzo(b,d)pyran-1-ol, 6a,7,8,10a-tetrahydro-6,6,9-trimethyl-3-pentyl-, (6aR-trans)- |
| 9 ene Tetrahydrocannabinol |
| 9-ene-Tetrahydrocannabinol |
| Abbott 40566 |
| Delta 9-Tetrahydrocannabinol |
| DELTA THC 09 |
| delta(1)-Tetrahydrocannabinol |
| delta(1)-THC |
| delta(9)-Tetrahydrocannabinol |
| Delta(9)-Tetrahydrocannibinol |
| delta(9)-THC |
| delta-9-Tetrahydrocannabinol (substance) |
| delta-9-tetrahydrocannabinol |
| delta-9-THC |
| delta9-Tetrahydrocannabinol |
| Delta9-THC |
| Dronabinol (substance) |
| Dronabinol [Chemical/Ingredient] |
| Dronabinolum |
| Dronabinol |
| Marinol |
| Product containing dronabinol (medicinal product) |
| Product containing dronabinol |
| SP 104 |
| SP-104 |
| Synthetic delta-9-Tetrahydrocannabinol |
| Tetrahydro-6,6,9-trimethyl-3-pentyl-6H-dibenzo(b,d)pyran-1-ol |
| Tetrahydrocannabinol (substance) |
| tetrahydrocannabinol |
| THC |
| Δ9-tetrahydrocannabinol |
External Source Codes:
| NCI Thesaurus Code | C867 (see NCI Thesaurus info) |
| CAS Registry Number | 1972-08-3 (see NLM ChemIDplus info) |
| FDA UNII Code | 7J8897W37S |
| NSC Code | 134454 (see NCI DTP info) |
| PDQ Closed Trial Search ID | 39707 |
| PDQ Open Trial Search ID | 39707 (check for NCI PDQ open clinical trial info) |
Other Properties:
| Name | Value | Source |
|---|---|---|
| ACTIVE | 1 | SNOMEDCT_US |
| AQL | AA AD AE AG AI AN BI BL CF CH CL CS CT EC HI IM IP ME PD PK PO RE SD ST TO TU UR | MSH |
| CASE_SIGNIFICANCE_ID | 900000000000017005 | SNOMEDCT_US |
| CASE_SIGNIFICANCE_ID | 900000000000020002 | SNOMEDCT_US |
| CASE_SIGNIFICANCE_ID | 900000000000448009 | SNOMEDCT_US |
| CHARACTERISTIC_TYPE_ID | 900000000000011006 | SNOMEDCT_US |
| Chemical_Formula | C21H30O2 | NCI |
| Contributing_Source | CTRP | NCI |
| Contributing_Source | FDA | NCI |
| CTV3ID | XU27h | SNOMEDCT_US |
| CTV3ID | XUJfM | SNOMEDCT_US |
| CTV3ID | XUOeA | SNOMEDCT_US |
| CTV3ID | XUWml | SNOMEDCT_US |
| DATE_LAST_MODIFIED | 2016-07-29 | PDQ |
| DC | 1 | MSH |
| DEFINITION_STATUS_ID | 900000000000074008 | SNOMEDCT_US |
| DID | 0396-2636 | CSP |
| DX | 19770101 | MSH |
| EFFECTIVE_TIME | 20020131 | SNOMEDCT_US |
| EFFECTIVE_TIME | 20030131 | SNOMEDCT_US |
| EFFECTIVE_TIME | 20080131 | SNOMEDCT_US |
| FDA_UNII_CODE | 7J8897W37S | DRUGBANK |
| FDA_UNII_CODE | 7J8897W37S | NDFRT |
| HN | 2014(1971); | MSH |
| HN | ETOH descriptor 1995. | AOD |
| LEVEL | Example Part D Eligible Drugs | USPMG |
| LEVEL | Ingredient | NDFRT |
| LT | TRD | MSH |
| LT | TRD | MTH |
| LT | TRD | PDQ |
| MDA | 19990101 | MSH |
| MESH_DEFINITION | A psychoactive compound extracted from the resin of Cannabis sativa (marihuana, hashish). The isomer delta-9-tetrahydrocannabinol (THC) is considered the most active form, producing characteristic mood and perceptual changes associated with this compound. | NDFRT |
| MESH_DUI | D013759 | NDFRT |
| MESH_NAME | Dronabinol | NDFRT |
| MESH_UI | M0021229 | NDFRT |
| MMR | 20160701 | MSH |
| MN | D02.455.849.090.810 | MSH |
| MODIFIER_ID | 900000000000451002 | SNOMEDCT_US |
| NCI_THESAURUS_CODE | C867 | PDQ |
| NDFRT_KIND | DRUG_KIND | NDFRT |
| NDFRT_KIND | INGREDIENT_KIND | NDFRT |
| NUI | N0000006283 | NDFRT |
| NUI | N0000146833 | NDFRT |
| ORIG_STY | Drug/agent | PDQ |
| PA | D006213 | MSH |
| PA | D011619 | MSH |
| PA | D018712 | MSH |
| PA | D063386 | MSH |
| PID | 2369 | PDQ |
| PM | 2014; seeTETRAHDYROCANNABINOL 1971-2013 | MSH |
| RN | 0 | MSH |
| RN | 7J8897W37S | MSH |
| RR | 17766-02-8 | MSH |
| RR | 1972-08-3 (Tetrahydrocannabinol) | MSH |
| RR | 3556-79-4 | MSH |
| RR | 43009-38-7 | MSH |
| RR | 6465-30-1 | MSH |
| RR | 69855-10-3 | MSH |
| RXAUI | 1190064 | RXNORM |
| RXAUI | 2070666 | RXNORM |
| RXAUI | 2637964 | RXNORM |
| RXAUI | 3094483 | RXNORM |
| RXAUI | 3094708 | RXNORM |
| RXAUI | 3142833 | RXNORM |
| RXAUI | 3142834 | RXNORM |
| RXAUI | 3244317 | RXNORM |
| RXAUI | 3259970 | RXNORM |
| RXAUI | 3259972 | RXNORM |
| RXAUI | 3259974 | RXNORM |
| RXAUI | 3259975 | RXNORM |
| RXAUI | 3304289 | RXNORM |
| RXAUI | 332691 | RXNORM |
| RXAUI | 3868354 | RXNORM |
| RXAUI | 5930758 | RXNORM |
| RXAUI | 5930759 | RXNORM |
| RXAUI | 5932351 | RXNORM |
| RXAUI | 5933125 | RXNORM |
| RXCUI | 10402 | RXNORM |
| RXCUI | 224925 | RXNORM |
| RXN_BN_CARDINALITY | single | RXNORM |
| SID | APRD00571 | DRUGBANK |
| SOS | Active ingredient of hashish. | AOD |
| SOS | Tetrahydrocannabinol, a psychoactive alkaloid of the cannabis plant, first synthesized in 1965. One of many cannabis derivatives, it is believed to produce the primary psychoactive effects of marijuana. Hashish usually contains about 12 percent THC and up to 40 percent hash oil. Because pure THC is expensive to produce and loses its potency rapidly upon exposure to air, much of what is sold on the streets as THC is PCP or LSD. | AOD |
| SPL_SET_ID | 08adbfd9-789a-4888-a9e2-2a6dac867885 | MTHSPL |
| SPL_SET_ID | 1f1af798-17d5-47d0-b129-21d4aa1eb125 | MTHSPL |
| SPL_SET_ID | 5050ed63-c6bc-4761-9a81-ef8e5f3f378e | MTHSPL |
| SPL_SET_ID | 5bbac0b1-ddc2-400b-8e0d-1e1d484720ca | MTHSPL |
| SPL_SET_ID | 68b4168b-5782-4e68-a25a-5b4e4408dbce | MTHSPL |
| SPL_SET_ID | a0409d82-a61e-4b9e-8717-ced299ccedb2 | MTHSPL |
| SPL_SET_ID | a6269fc3-ca40-444f-8035-d6a391d037e0 | MTHSPL |
| SUBSET_MEMBER | 900000000000497000~MAPTARGET~XU27h | SNOMEDCT_US |
| SUBSET_MEMBER | 900000000000497000~MAPTARGET~XUJfM | SNOMEDCT_US |
| SUBSET_MEMBER | 900000000000497000~MAPTARGET~XUOeA | SNOMEDCT_US |
| SUBSET_MEMBER | 900000000000497000~MAPTARGET~XUWml | SNOMEDCT_US |
| SUBSET_MEMBER | 900000000000508004~ACCEPTABILITYID~900000000000548007 | SNOMEDCT_US |
| SUBSET_MEMBER | 900000000000508004~ACCEPTABILITYID~900000000000549004 | SNOMEDCT_US |
| SUBSET_MEMBER | 900000000000509007~ACCEPTABILITYID~900000000000548007 | SNOMEDCT_US |
| SUBSET_MEMBER | 900000000000509007~ACCEPTABILITYID~900000000000549004 | SNOMEDCT_US |
| TERMUI | T040421 | MSH |
| TERMUI | T040422 | MSH |
| TERMUI | T040423 | MSH |
| TERMUI | T040424 | MSH |
| TERMUI | T040425 | MSH |
| TERMUI | T040426 | MSH |
| TERMUI | T040427 | MSH |
| TERMUI | T040428 | MSH |
| TERMUI | T040429 | MSH |
| TH | CA | MSH |
| TH | FDA SRS (2014) | MSH |
| TH | INN (19XX) | MSH |
| TH | NLM (1971) | MSH |
| TH | NLM (1992) | MSH |
| TH | NLM (1994) | MSH |
| TH | NLM (1997) | MSH |
| TH | UNK (19XX) | MSH |
| TH | USAN (1984) | MSH |
| TH | USP (19XX) | MSH |
| TH | US | MSH |
| TYPE_ID | 900000000000003001 | SNOMEDCT_US |
| TYPE_ID | 900000000000013009 | SNOMEDCT_US |
| VANDF_RECORD | 50.416^1109^Active/Master | NDFRT |
| VANDF_RECORD | 50.6^827^Active/Master | NDFRT |
| VUID | 4018511 | NDFRT |
Additional Concept Data: (none)
URL to Bookmark: https://ncim-stage.nci.nih.gov/ncimbrowser/ConceptReport.jsp?dictionary=NCI Metathesaurus&code=C0039663
