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Syncope (CUI C0039070) Suggest changes to this concept
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Terms & Properties

Concept Unique Identifier (CUI): C0039070

NCI Thesaurus Code: C35053  (see NCI Thesaurus info)

Semantic Type: Sign or Symptom

NCIt Definition: A spontaneous loss of consciousness caused by insufficient blood supply to the brain.

HPO Definition: Syncope refers to a generalized weakness of muscles with loss of postural tone, inability to stand upright, and loss of consciousness. Once the patient is in a horizontal position, blood flow to the brain is no longer hindered by gravitation and consciousness is regained. Unconsciousness usually lasts for seconds to minutes. Headache and drowsiness (which usually follow seizures) do not follow a syncopal attack. Syncope results from a sudden impairment of brain metabolism usually due to a reduction in cerebral blood flow. [HPO:probinson]

MEDLINEPLUS Definition: 

Fainting is a temporary loss of consciousness. If you're about to faint, you'll feel dizzy, lightheaded, or nauseous. Your field of vision may "white out" or "black out." Your skin may be cold and clammy. You lose muscle control at the same time, and may fall down.

Fainting usually happens when your blood pressure drops suddenly, causing a decrease in blood flow to your brain. It is more common in older people. Some causes of fainting include

  • Heat or dehydration
  • Emotional distress
  • Standing up too quickly
  • Certain medicines
  • Drop in blood sugar
  • Heart problems

When someone faints, make sure that the airway is clear and check for breathing. The person should stay lying down for 10-15 minutes. Most people recover completely. Fainting is usually nothing to worry about, but it can sometimes be a sign of a serious problem. If you faint, it's important to see your health care provider and find out why it happened.

CTCAE Definition: A disorder characterized by spontaneous loss of consciousness caused by insufficient blood supply to the brain.

NICHD Definition: Transitory loss of consciousness and postural tone.

CSP Definition: fainting due to a sudden fall of blood pressure below the level required to maintain oxygenation of brain tissue.

MSH Definition: A transient loss of consciousness and postural tone caused by diminished blood flow to the brain (i.e., BRAIN ISCHEMIA). Presyncope refers to the sensation of lightheadedness and loss of strength that precedes a syncopal event or accompanies an incomplete syncope. (From Adams et al., Principles of Neurology, 6th ed, pp367-9)

Synonyms & Abbreviations: (see Synonym Details)
Collapse fleeting
Collapse transient
FAINTING EPISODES
Fainting/syncope
fainting
Faintness
Faint
Falling out
Passed out
Swooning
Syncopal attack
Syncope (disorder)
Syncope [Disease/Finding]
Syncope and collapse (disorder)
Syncope and collapse (R55)
Syncope and collapse
Syncope attack
Syncope symptom (disorder)
Syncope symptom
Syncopes
syncope

External Source Codes: 
NCI Thesaurus Code C35053 (see NCI Thesaurus info)

Other Properties: Property Definitions
Name Value Source
ACTIVE 1 SNOMEDCT_US
AQL BL CF CI CL CN CO DG DH DI DT EC EH EM EN EP ET GE HI IM ME MI MO NU PA PC PP PS PX RH RT SU TH UR VE VI MSH
CASE_SIGNIFICANCE_ID 900000000000020002 SNOMEDCT_US
CHARACTERISTIC_TYPE_ID 900000000000011006 SNOMEDCT_US
Contributing_Source CTCAE NCI
Contributing_Source FDA NCI
Contributing_Source MedDRA NCI
Contributing_Source NICHD NCI
CTV3ID XaBua SNOMEDCT_US
CTV3ID XM010 SNOMEDCT_US
CTV3ID XM0CY SNOMEDCT_US
DATE_CREATED 05/16/2001 MEDLINEPLUS
DATE_CREATED 2008-02-25T10:37:00Z HPO
DC 1 MSH
DEFINITION_STATUS_ID 900000000000074008 SNOMEDCT_US
DID 2056-8027 CSP
DX 19660101 MSH
EFFECTIVE_TIME 20020131 SNOMEDCT_US
EXCLUDES1 cardiogenic shock (R57.0) ICD10CM
EXCLUDES1 carotid sinus syncope (G90.01) ICD10CM
EXCLUDES1 heat syncope (T67.1) ICD10CM
EXCLUDES1 neurocirculatory asthenia (F45.8) ICD10CM
EXCLUDES1 neurogenic orthostatic hypotension (G90.3) ICD10CM
EXCLUDES1 orthostatic hypotension (I95.1) ICD10CM
EXCLUDES1 postprocedural shock (T81.1-) ICD10CM
EXCLUDES1 psychogenic syncope (F48.8) ICD10CM
EXCLUDES1 shock complicating or following abortion or ectopic or molar pregnancy (O00-O07, O08.3) ICD10CM
EXCLUDES1 shock complicating or following labor and delivery (O75.1) ICD10CM
EXCLUDES1 shock NOS (R57.9) ICD10CM
EXCLUDES1 Stokes-Adams attack (I45.9) ICD10CM
EXCLUDES1 unconsciousness NOS (R40.2-) ICD10CM
EXTERNALLY_DEFINED N LNC
FDA_Table Patient Code (Appendix B) NCI
FX D014474 MSH
IAN DEFAULT ICD10
ICE Blackout; Fainting; (Near) (Pre)syncope; Vasovagal attack ICD9CM
INCLUSION_TERM Blackout ICD10
INCLUSION_TERM Fainting ICD10
IPX R55 ICPC
MDA 19990101 MSH
MESH_DEFINITION A transient loss of consciousness and postural tone caused by diminished blood flow to the brain (i.e., BRAIN ISCHEMIA). Presyncope refers to the sensation of lightheadedness and loss of strength that precedes a syncopal event or accompanies an incomplete syncope. (From Adams et al., Principles of Neurology, 6th ed, pp367-9) NDFRT
MESH_DUI D013575 NDFRT
MESH_NAME Syncope NDFRT
MESH_UI M0020955 NDFRT
MMR 19991126 MSH
MN C10.597.606.358.800.600 MSH
MN C23.888.592.604.359.800.600 MSH
MODIFIER_ID 900000000000451002 SNOMEDCT_US
MP_HEALTH_TOPIC_URL https://www.nlm.nih.gov/medlineplus/fainting.html MEDLINEPLUS
MP_OTHER_LANGUAGE_URL Spanish https://www.nlm.nih.gov/medlineplus/spanish/fainting.html MEDLINEPLUS
MP_PRIMARY_INSTITUTE_URL National Heart, Lung, and Blood Institute http://www.nhlbi.nih.gov/ MEDLINEPLUS
NDFRT_KIND DISEASE_KIND NDFRT
NICHD_Hierarchy_Term Syncope NCI
NUI N0000002873 NDFRT
ORDER_NO 28783 ICD10CM
PRIMARY_PATH 10042772$10013509$10029305$10029205$Syncope$Disturbances in consciousness NEC$Neurological disorders NEC$Nervous system disorders MDR
PRIMARY_SOC 10029205 MDR
PT_IN_VERSION 10.0 MDR
PT_IN_VERSION 10.1 MDR
PT_IN_VERSION 11.0 MDR
PT_IN_VERSION 11.1 MDR
PT_IN_VERSION 12.0 MDR
PT_IN_VERSION 12.1 MDR
PT_IN_VERSION 13.0 MDR
PT_IN_VERSION 13.1 MDR
PT_IN_VERSION 14.0 MDR
PT_IN_VERSION 14.1 MDR
PT_IN_VERSION 15.0 MDR
PT_IN_VERSION 15.1 MDR
PT_IN_VERSION 16.0 MDR
PT_IN_VERSION 16.1 MDR
PT_IN_VERSION 17.0 MDR
PT_IN_VERSION 17.1 MDR
PT_IN_VERSION 18.0 MDR
PT_IN_VERSION 18.1 MDR
PT_IN_VERSION 19.0 MDR
PT_IN_VERSION 19.1 MDR
PT_IN_VERSION 8.0 MDR
PT_IN_VERSION 8.1 MDR
PT_IN_VERSION 9.0 MDR
PT_IN_VERSION 9.1 MDR
RXAUI 3159642 RXNORM
RXAUI 3241989 RXNORM
RXAUI 3241990 RXNORM
RXCUI 1023272 RXNORM
SMQ_TERM_ADDVERSION 10.1 MDR
SMQ_TERM_ADDVERSION 11.1 MDR
SMQ_TERM_ADDVERSION 12.0 MDR
SMQ_TERM_ADDVERSION 12.1 MDR
SMQ_TERM_ADDVERSION 14.1 MDR
SMQ_TERM_ADDVERSION 15.1 MDR
SMQ_TERM_ADDVERSION 16.0 MDR
SMQ_TERM_ADDVERSION 19.0 MDR
SMQ_TERM_ADDVERSION 7.1 MDR
SMQ_TERM_ADDVERSION 8.1 MDR
SMQ_TERM_ADDVERSION 9.0 MDR
SMQ_TERM_ADDVERSION 9.1 MDR
SMQ_TERM_CAT A MDR
SMQ_TERM_CAT B MDR
SMQ_TERM_CAT C MDR
SMQ_TERM_CAT D MDR
SMQ_TERM_LEVEL 4 MDR
SMQ_TERM_LEVEL 5 MDR
SMQ_TERM_LMVERSION 10.1 MDR
SMQ_TERM_LMVERSION 11.1 MDR
SMQ_TERM_LMVERSION 12.0 MDR
SMQ_TERM_LMVERSION 12.1 MDR
SMQ_TERM_LMVERSION 14.1 MDR
SMQ_TERM_LMVERSION 15.1 MDR
SMQ_TERM_LMVERSION 16.0 MDR
SMQ_TERM_LMVERSION 19.0 MDR
SMQ_TERM_LMVERSION 7.1 MDR
SMQ_TERM_LMVERSION 8.1 MDR
SMQ_TERM_LMVERSION 9.0 MDR
SMQ_TERM_LMVERSION 9.1 MDR
SMQ_TERM_SCOPE 1 MDR
SMQ_TERM_SCOPE 2 MDR
SMQ_TERM_STATUS A MDR
SMQ_TERM_WEIGHT 0 MDR
SNOMED_CID 271594007 NDFRT
SNOMED_CID 272030005 NDFRT
SNOMED_CID 309585006 NDFRT
SNOMEDID D3-00004 SNOMEDCT_US
SNOMEDID D3-00006 SNOMEDCT_US
SNOMEDID D3-0000D SNOMEDCT_US
SOS Excludes: carotid sinus syncope (337.0); heat syncope (992.1); neurocirculatory asthenia (306.2); orthostatic hypotension (458.0); shock NOS (785.50) ICD9CM
SUBSET_MEMBER 447562003~CORRELATIONID~447561005 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPADVICE~ALWAYS R55 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPCATEGORYID~447637006 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPGROUP~1 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPPRIORITY~1 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPRULE~TRUE SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPTARGET~R55 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~CORRELATIONID~447561005 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~ALWAYS R55 | DESCENDANTS NOT EXHAUSTIVELY MAPPED SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~ALWAYS R55 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPCATEGORYID~447637006 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPGROUP~1 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~1 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~TRUE SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~R55 SNOMEDCT_US
SUBSET_MEMBER 900000000000497000~MAPTARGET~XaBua SNOMEDCT_US
SUBSET_MEMBER 900000000000497000~MAPTARGET~XM010 SNOMEDCT_US
SUBSET_MEMBER 900000000000497000~MAPTARGET~XM0CY SNOMEDCT_US
SUBSET_MEMBER 900000000000498005~MAPTARGET~D3-00004 SNOMEDCT_US
SUBSET_MEMBER 900000000000498005~MAPTARGET~D3-00006 SNOMEDCT_US
SUBSET_MEMBER 900000000000498005~MAPTARGET~D3-0000D SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
TERMUI T039906 MSH
TERMUI T039907 MSH
TH NLM (1966) MSH
TH UNK (19XX) MSH
TYPE_ID 900000000000003001 SNOMEDCT_US
TYPE_ID 900000000000013009 SNOMEDCT_US

Additional Concept Data:  (none)

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