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Aphthous Stomatitis (CUI C0038363) Suggest changes to this concept
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Terms & Properties

Concept Unique Identifier (CUI): C0038363

NCI Thesaurus Code: C62546  (see NCI Thesaurus info)

Semantic Type: Disease or Syndrome

NCIt Definition: A recurrent disease of the oral mucosa of unknown etiology. It is characterized by small white ulcerative lesions, single or multiple, round or oval, lasting for 7-14 days and healing without scarring.

MEDLINEPLUS Definition: 

Canker sores are small, round sores on the inside of the cheek, under the tongue, or in the back of the throat. They usually have a red edge and a gray center. They can be quite painful. They are not the same as cold sores, which are caused by herpes simplex.

Canker sores aren't contagious. They may happen if you have a viral infection. They may also be triggered by stress, food allergies, lack of vitamins and minerals, hormonal changes or menstrual periods. In some cases the cause is unknown.

In most cases, the sores go away by themselves. Some ointments, creams or rinses may help with the pain. Avoiding hot, spicy food while you have a canker sore also helps.

NICHD Definition: A term used to describe oral, non-keratinized mucosal ulcerations that are shallow, round to oval with a grayish base, and are usually painful. Recurrent aphthous ulcers are often associated with predisposing factors such as stress, familial tendency, trauma, drug hypersensitivity, or underlying disease such as inflammatory bowel disease, systemic lupus erythematosus, and Behcet disease.

CSP Definition: recurrent disease of the oral mucosa of unknown etiology, characterized by small white ulcerative lesions lasting 7 to 14 days.

MSH Definition: A recurrent disease of the oral mucosa of unknown etiology. It is characterized by small white ulcerative lesions, single or multiple, round or oval. Two to eight crops of lesions occur per year, lasting for 7 to 14 days and then heal without scarring. (From Jablonski's Dictionary of Dentistry, 1992, p742)

Synonyms & Abbreviations: (see Synonym Details)
Aphtha (morphologic abnormality)
Aphthae minor
Aphthae
Aphtha
Aphthous Stomatitides
Aphthous Stomatitis
Aphthous ulcer of mouth (disorder)
Aphthous ulcer of mouth
aphthous ulcers
aphthous ulcer
CANKER SORES ORAL
Canker Sores
CANKER SORE
MIAU - Minor aphthous ulceration
Minor oral aphthous ulceration (disorder)
Minor oral aphthous ulceration
Oral aphthae
Sore, Canker
Sores, Canker
Stomatitides, Aphthous
STOMATITIS APHHNOUS
STOMATITIS APHTHOUS
Stomatitis, Aphthous [Disease/Finding]
STOMATITIS, APHTHOUS
ULCER APHTHOUS ORAL
Ulcer aphthous
Ulcer, Aphthous
Ulcerative stomatitis NOS
Ulcers aphthous oral
Ulcers, Aphthous

External Source Codes: 
NCI Thesaurus Code C62546 (see NCI Thesaurus info)

Other Properties: Property Definitions
Name Value Source
ACTIVE 1 SNOMEDCT_US
AN do not confuse X refs ULCER, APHTHOUS or CANKER SORE with "oral ulcers" ( = ORAL ULCER ) MSH
AQL BL CF CI CL CN CO DG DH DI DT EC EH EM EN EP ET GE HI IM ME MI MO NU PA PC PP PS PX RH RT SU TH UR VE VI MSH
CASE_SIGNIFICANCE_ID 900000000000017005 SNOMEDCT_US
CASE_SIGNIFICANCE_ID 900000000000448009 SNOMEDCT_US
CHARACTERISTIC_TYPE_ID 900000000000011006 SNOMEDCT_US
Contributing_Source NICHD NCI
CTV3ID XaBEJ SNOMEDCT_US
CTV3ID XU2ce SNOMEDCT_US
CTV3ID XUfaU SNOMEDCT_US
DATE_CREATED 10/01/2012 MEDLINEPLUS
DC 1 MSH
DEFINITION_STATUS_ID 900000000000073002 SNOMEDCT_US
DEFINITION_STATUS_ID 900000000000074008 SNOMEDCT_US
DID 2139-2521 CSP
DX 19650101 MSH
EFFECTIVE_TIME 20020131 SNOMEDCT_US
EFFECTIVE_TIME 20070731 SNOMEDCT_US
HAS_GARD_PAGE true GARD
HN 65 MSH
ICE Aphthous stomatitis; Canker sore; Periadenitis mucosa necrotica recurrens; Recurrent aphthous ulcer; Stomatitis herpetiformis ICD9CM
IS_RARE true GARD
IS_SPANISH false GARD
MDA 19990101 MSH
MESH_DEFINITION A recurrent disease of the oral mucosa of unknown etiology. It is characterized by small white ulcerative lesions, single or multiple, round or oval. Two to eight crops of lesions occur per year, lasting for 7 to 14 days and then heal without scarring. (From Jablonski's Dictionary of Dentistry, 1992, p742) NDFRT
MESH_DUI D013281 NDFRT
MESH_NAME Stomatitis, Aphthous NDFRT
MESH_UI M0020551 NDFRT
MMR 20050630 MSH
MN C07.465.864.750 MSH
MODIFIER_ID 900000000000451002 SNOMEDCT_US
MP_HEALTH_TOPIC_URL https://www.nlm.nih.gov/medlineplus/cankersores.html MEDLINEPLUS
MP_OTHER_LANGUAGE_URL Spanish https://www.nlm.nih.gov/medlineplus/spanish/cankersores.html MEDLINEPLUS
MP_PRIMARY_INSTITUTE_URL National Institute of Dental and Craniofacial Research http://www.nidcr.nih.gov/ MEDLINEPLUS
NDFRT_KIND DISEASE_KIND NDFRT
NICHD_Hierarchy_Term Aphthous Ulcer NCI
NUI N0000002833 NDFRT
PM 65 MSH
PRIMARY_PATH 10002959$10042129$10031013$10017947$Aphthous ulcer$Stomatitis and ulceration$Oral soft tissue conditions$Gastrointestinal disorders MDR
PRIMARY_SOC 10017947 MDR
PT_IN_VERSION 10.0 MDR
PT_IN_VERSION 10.1 MDR
PT_IN_VERSION 11.0 MDR
PT_IN_VERSION 11.1 MDR
PT_IN_VERSION 12.0 MDR
PT_IN_VERSION 12.1 MDR
PT_IN_VERSION 13.0 MDR
PT_IN_VERSION 13.1 MDR
PT_IN_VERSION 14.0 MDR
PT_IN_VERSION 14.1 MDR
PT_IN_VERSION 15.0 MDR
PT_IN_VERSION 15.1 MDR
PT_IN_VERSION 16.0 MDR
PT_IN_VERSION 16.1 MDR
PT_IN_VERSION 17.0 MDR
PT_IN_VERSION 17.1 MDR
PT_IN_VERSION 18.0 MDR
PT_IN_VERSION 18.1 MDR
PT_IN_VERSION 19.0 MDR
PT_IN_VERSION 19.1 MDR
PT_IN_VERSION 20.0 MDR
PT_IN_VERSION 20.1 MDR
PT_IN_VERSION 8.0 MDR
PT_IN_VERSION 8.1 MDR
PT_IN_VERSION 9.0 MDR
PT_IN_VERSION 9.1 MDR
RARE_DISEASE_URL http://rarediseases.info.nih.gov/gard/5834/aphthous-stomatitis/resources/1 GARD
RXAUI 3110867 RXNORM
RXAUI 3129753 RXNORM
RXAUI 3240613 RXNORM
RXAUI 3240614 RXNORM
RXAUI 3252440 RXNORM
RXCUI 1023942 RXNORM
SMQ_TERM_ADDVERSION 10.1 MDR
SMQ_TERM_CAT A MDR
SMQ_TERM_LEVEL 4 MDR
SMQ_TERM_LEVEL 5 MDR
SMQ_TERM_LMVERSION 13.0 MDR
SMQ_TERM_LMVERSION 18.1 MDR
SMQ_TERM_SCOPE 2 MDR
SMQ_TERM_STATUS A MDR
SMQ_TERM_WEIGHT 0 MDR
SNOMED_CID 321258009 NDFRT
SOS Excludes: herpetic stomatitis (054.2) ICD9CM
SUBSET_MEMBER 447562003~CORRELATIONID~447561005 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPADVICE~ALWAYS K12.0 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPCATEGORYID~447637006 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPGROUP~1 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPPRIORITY~1 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPRULE~TRUE SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPTARGET~K12.0 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~CORRELATIONID~447561005 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~ALWAYS K12.0 | CONSIDER ADDITIONAL CODE TO IDENTIFY SPECIFIC CONDITION OR DISEASE SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~IF MOUTH AND GENITAL ULCERS WITH INFLAMED CARTILAGE SYNDROME AND IF FEMALE CHOOSE N76.6 | CONSIDER ADDITIONAL CODE TO IDENTIFY SPECIFIC CONDITION OR DISEASE | MAP IS CONTEXT DEPENDENT FOR GENDER SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~IF MOUTH AND GENITAL ULCERS WITH INFLAMED CARTILAGE SYNDROME AND IF MALE CHOOSE N50.89 | MAP IS CONTEXT DEPENDENT FOR GENDER SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~IF MOUTH AND GENITAL ULCERS WITH INFLAMED CARTILAGE SYNDROME CHOOSE M94.1 | MAP OF SOURCE CONCEPT IS CONTEXT DEPENDENT SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~IF PFAPA SYNDROME CHOOSE I88.9 | MAP OF SOURCE CONCEPT IS CONTEXT DEPENDENT SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~IF PFAPA SYNDROME CHOOSE J02.9 | MAP OF SOURCE CONCEPT IS CONTEXT DEPENDENT SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~IF PFAPA SYNDROME CHOOSE K12.0 | CONSIDER ADDITIONAL CODE TO IDENTIFY SPECIFIC CONDITION OR DISEASE | MAP OF SOURCE CONCEPT IS CONTEXT DEPENDENT SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~IF PFAPA SYNDROME CHOOSE M04.1 | MAP OF SOURCE CONCEPT IS CONTEXT DEPENDENT SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~MAP SOURCE CONCEPT CANNOT BE CLASSIFIED WITH AVAILABLE DATA SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPCATEGORYID~447637006 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPCATEGORYID~447638001 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPCATEGORYID~447639009 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPGROUP~1 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPGROUP~2 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPGROUP~3 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPGROUP~4 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~1 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~2 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~3 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~4 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~5 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~IFA 238850005 | Mouth and genital ulcers with inflamed cartilage syndrome | AND IFA 248152002 | Female (finding) | SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~IFA 238850005 | Mouth and genital ulcers with inflamed cartilage syndrome | AND IFA 248153007 | Male (finding) | SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~IFA 238850005 | Mouth and genital ulcers with inflamed cartilage syndrome | SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~IFA 717231003 | PFAPA syndrome | SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~OTHERWISE TRUE SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~TRUE SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~I88.9 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~J02.9 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~K12.0 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~M04.1 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~M94.1 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~N50.89 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~N76.6 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~ SNOMEDCT_US
SUBSET_MEMBER 900000000000497000~MAPTARGET~XaBEJ SNOMEDCT_US
SUBSET_MEMBER 900000000000497000~MAPTARGET~XU2ce SNOMEDCT_US
SUBSET_MEMBER 900000000000497000~MAPTARGET~XUfaU SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
TERMUI T039009 MSH
TERMUI T039010 MSH
TERMUI T039011 MSH
TERMUI T039012 MSH
TH NLM (1965) MSH
TH UNK (19XX) MSH
TYPE_ID 900000000000003001 SNOMEDCT_US
TYPE_ID 900000000000013009 SNOMEDCT_US

Additional Concept Data:  (none)

URL to Bookmark: https://ncim-stage.nci.nih.gov/ncimbrowser/ConceptReport.jsp?dictionary=NCI Metathesaurus&code=C0038363

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