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Silicosis (CUI C0037116) Suggest changes to this concept
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Terms & Properties

Concept Unique Identifier (CUI): C0037116

NCI Thesaurus Code: C3369  (see NCI Thesaurus info)

Semantic Type: Disease or Syndrome

NCIt Definition: An occupational lung disorder caused by the inhalation of silica dust. It results in the inflammation and scarring of the upper lobes of the lungs. It may be an acute or chronic disorder. In the acute form, patients develop shortness of breath, fever, and cyanosis. In the chronic form patients, develop progressive shortness of breath.

RADLEX Definition: Pneumoconiosis due to the inhalation of dust of stone, sand, or flint containing silicon dioxide, with formation of generalized, nodular fibrotic changes in both lungs. (Dorland, 27th ed) [MeSH]

GARD Definition: 

Silicosis is a respiratory disease caused by breathing in (inhaling) silica dust. There are three types of silicosis:

  • Simple chronic silicosis, the most common type of silicosis, results from long-term exposure (usually more than 20 years) to low amounts of silica dust. Simple chronic silicosis may cause people to have difficulty breathing. 
  • Accelerated silicosis occurs after 5 to 15 years of exposure of higher levels of silica. Swelling of the lungs and other symptoms occur faster in this type of silicosis than in the simple chronic form. 
  • Acute silicosis results from short-term exposure of large amounts of silica. The lungs become very inflamed and can fill with fluid, causing severe shortness of breath and low blood oxygen levels. Acute silicosis progresses rapidly and can be fatal within months. 

People who work in jobs where they are exposed to silica dust (mining, quarrying, construction, sand blasting, stone cutting) are at risk of developing this condition.

- this information is from GARD/ORDR/NCATS.

MSH Definition: A form of pneumoconiosis resulting from inhalation of dust containing crystalline form of SILICON DIOXIDE, usually in the form of quartz. Amorphous silica is relatively nontoxic.

Synonyms & Abbreviations: (see Synonym Details)
Nodular silicosis
Pneumoconiosis caused by silica (disorder)
Pneumoconiosis caused by silicate (disorder)
Pneumoconiosis caused by silicate
Pneumoconiosis caused by silica
Pneumoconiosis due to dust containing silica
Pneumoconiosis due to other silica or silicates
Pneumoconiosis due to silicates
Pneumoconiosis due to silicate
Pneumoconiosis due to silica
Silica pneumocon NEC
SILICATOSIS
Silicoses
Silicosis [Disease/Finding]
Silicosis NOS
silicosis
Silicotic fibrosis of lung
Silikose

External Source Codes: 
NCI Thesaurus Code C3369 (see NCI Thesaurus info)

Other Properties: Property Definitions
Name Value Source
ACTIVE 1 SNOMEDCT_US
AN ANTHRACOSILICOSIS & SILICOTUBERCULOSIS are also available; do not coordinate with OCCUPATIONAL DISEASES MSH
AQL BL CF CL CN CO DG DH DI DT EC EH EM EN EP ET GE HI IM ME MI MO NU PA PC PP PS PX RH RT SU TH UR VE VI MSH
CASE_SIGNIFICANCE_ID 900000000000448009 SNOMEDCT_US
CHARACTERISTIC_TYPE_ID 900000000000011006 SNOMEDCT_US
CTV3ID H42.. SNOMEDCT_US
CTV3ID XUfaH SNOMEDCT_US
DC 1 MSH
DEFINITION_STATUS_ID 900000000000073002 SNOMEDCT_US
DID 2596-4484 CSP
DX 19660101 MSH
EFFECTIVE_TIME 20020731 SNOMEDCT_US
EFFECTIVE_TIME 20070731 SNOMEDCT_US
EXCLUDES1 pneumoconiosis with tuberculosis, any type in A15 (J65) ICD10CM
HAS_GARD_PAGE true GARD
IAN DEFAULT ICD10
ICE Pneumoconiosis due to talc; Silicotic fibrosis (massive) of lung; Silicosis (simple) (complicated) ICD9CM
INCLUSION_TERM silicotic fibrosis (massive) of lung ICD10
IS_RARE true GARD
IS_SPANISH false GARD
LAST_REVIEW_ACTION Modified GARD
LAST_REVIEW_DATE 2013-10-10T00:00:00 GARD
MDA 19990101 MSH
MESH_DEFINITION A form of pneumoconiosis resulting from inhalation of dust containing crystalline form of SILICON DIOXIDE, usually in the form of quartz. Amorphous silica is relatively nontoxic. NDFRT
MESH_DUI D012829 NDFRT
MESH_NAME Silicosis NDFRT
MESH_UI M0019862 NDFRT
MMR 20100625 MSH
MN C08.381.483.581.760 MSH
MN C08.381.520.702.760 MSH
MN C24.800.834 MSH
MODIFIER_ID 900000000000451002 SNOMEDCT_US
NDFRT_KIND DISEASE_KIND NDFRT
NUI N0000002751 NDFRT
ORDER_NO 12614 ICD10CM
PRIMARY_PATH 10040678$10080710$10022114$10022117$Silicosis$Chest and respiratory tract injuries NEC$Injuries NEC$Injury, poisoning and procedural complications MDR
PRIMARY_SOC 10022117 MDR
PT_IN_VERSION 10.0 MDR
PT_IN_VERSION 10.1 MDR
PT_IN_VERSION 11.0 MDR
PT_IN_VERSION 11.1 MDR
PT_IN_VERSION 12.0 MDR
PT_IN_VERSION 12.1 MDR
PT_IN_VERSION 13.0 MDR
PT_IN_VERSION 13.1 MDR
PT_IN_VERSION 14.0 MDR
PT_IN_VERSION 14.1 MDR
PT_IN_VERSION 15.0 MDR
PT_IN_VERSION 15.1 MDR
PT_IN_VERSION 16.0 MDR
PT_IN_VERSION 16.1 MDR
PT_IN_VERSION 17.0 MDR
PT_IN_VERSION 17.1 MDR
PT_IN_VERSION 18.0 MDR
PT_IN_VERSION 18.1 MDR
PT_IN_VERSION 19.0 MDR
PT_IN_VERSION 19.1 MDR
PT_IN_VERSION 20.0 MDR
PT_IN_VERSION 20.1 MDR
PT_IN_VERSION 8.0 MDR
PT_IN_VERSION 8.1 MDR
PT_IN_VERSION 9.0 MDR
PT_IN_VERSION 9.1 MDR
RARE_DISEASE_URL http://rarediseases.info.nih.gov/gard/7647/silicosis/resources/1 GARD
RXAUI 3238316 RXNORM
RXAUI 3238317 RXNORM
RXCUI 1024247 RXNORM
SMQ_TERM_ADDVERSION 12.0 MDR
SMQ_TERM_CAT A MDR
SMQ_TERM_LEVEL 4 MDR
SMQ_TERM_LEVEL 5 MDR
SMQ_TERM_LMVERSION 14.0 MDR
SMQ_TERM_SCOPE 2 MDR
SMQ_TERM_STATUS I MDR
SMQ_TERM_WEIGHT 0 MDR
SNOMED_CID 805002 NDFRT
SNOMED_CID 83316006 NDFRT
SUBSET_MEMBER 447562003~CORRELATIONID~447561005 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPADVICE~ALWAYS J62.8 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPCATEGORYID~447637006 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPGROUP~1 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPPRIORITY~1 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPRULE~TRUE SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPTARGET~J62.8 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~CORRELATIONID~447561005 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~ALWAYS J62.8 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPCATEGORYID~447637006 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPGROUP~1 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~1 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~TRUE SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~J62.8 SNOMEDCT_US
SUBSET_MEMBER 900000000000497000~MAPTARGET~H42.. SNOMEDCT_US
SUBSET_MEMBER 900000000000497000~MAPTARGET~XUfaH SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
TERMUI T037826 MSH
TH NLM (1966) MSH
TYPE_ID 900000000000003001 SNOMEDCT_US
TYPE_ID 900000000000013009 SNOMEDCT_US

Additional Concept Data:  (none)

URL to Bookmark: https://ncim-stage.nci.nih.gov/ncimbrowser/ConceptReport.jsp?dictionary=NCI Metathesaurus&code=C0037116

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