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Retinopathy of Prematurity (CUI C0035344) Suggest changes to this concept
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Terms & Properties

Concept Unique Identifier (CUI): C0035344

NCI Thesaurus Code: C34982  (see NCI Thesaurus info)

Semantic Type: Disease or Syndrome

NCIt Definition: A bilateral retinopathy characterized by neovascularization, scarring, retinal detachment, and eventually blindness. It may be mild or severe. It occurs in babies born prematurely. Causes include oxygen toxicity and hypoxia.

RADLEX Definition: abnormal blood vessel development in the retina of the eye in a premature infant

NICHD Definition: A retinal condition of very immature infants that may be characterized by non-vascularized retina that may lead to neovascularization, scarring, retinal detachment, and blindness.

CSP Definition: bilateral retinopathy typically occurring in premature infants treated with high concentrations of oxygen; characterized by vascular dilation, proliferation, and tortuosity, edema, and retinal detachment with ultimate conversion of the retina into a fibrous mass; usually growth of the eye is arrested and may result in microophthalmia; blindness may occur.

MSH Definition: A bilateral retinopathy occurring in premature infants treated with excessively high concentrations of oxygen, characterized by vascular dilatation, proliferation, and tortuosity, edema, and retinal detachment, with ultimate conversion of the retina into a fibrous mass that can be seen as a dense retrolental membrane. Usually growth of the eye is arrested and may result in microophthalmia, and blindness may occur. (Dorland, 27th ed)

Synonyms & Abbreviations: (see Synonym Details)
Fibroplasia, Retrolental
Fibroplasias, Retrolental
premature retinopathy
Prematurity Retinopathies
Prematurity Retinopathy
Retinopathy of prematurity (disorder)
Retinopathy of Prematurity [Disease/Finding]
Retinopathy of prematurity NOS
Retinopathy of prematurity, unspecified
retinopathy of prematurity
Retinoph prematurity NOS
Retrolental Fibroplasias
Retrolental Fibroplasia
Retrolentale Fibroplasie
RLF - Retrolental fibroplasia
RLF
ROP - Retinopathy of prematurity
ROP
Terry Syndrome
Terry's syndrome

External Source Codes: 
NCI Thesaurus Code C34982 (see NCI Thesaurus info)

Other Properties: Property Definitions
Name Value Source
ACTIVE 1 SNOMEDCT_US
AN do not use /congen & do not coord with INFANT, NEWBORN, DISEASES; caused by oxygen ther of premature inf but for this etiol, do not use /chem ind: use /etiol if this etiol is discussed at all (& then probably NIM): TN 167 MSH
AQL BL CF CI CL CO DG DH DI DT EC EH EM EN EP ET GE HI IM ME MI MO NU PA PC PP PS PX RH RT SU TH UR VE VI MSH
CASE_SIGNIFICANCE_ID 900000000000017005 SNOMEDCT_US
CASE_SIGNIFICANCE_ID 900000000000448009 SNOMEDCT_US
CHARACTERISTIC_TYPE_ID 900000000000011006 SNOMEDCT_US
Contributing_Source MedDRA NCI
Contributing_Source NICHD NCI
CTV3ID XUckc SNOMEDCT_US
DATE_CREATED 2013-01-09T00:04:00 GARD
DATE_LAST_MODIFIED 2013-01-09T00:04:00 GARD
DC 1 MSH
DEFINITION_STATUS_ID 900000000000073002 SNOMEDCT_US
DID 1114-9578 CSP
DISEASE_IDENTIFIER_ID 16868 GARD
DISEASE_IDENTIFIER_ID 16869 GARD
DX 19870101 MSH
EFFECTIVE_TIME 20070131 SNOMEDCT_US
EXTERNALLY_DEFINED N LNC
HAS_GARD_PAGE true GARD
HN 87; was RETROLENTAL FIBROPLASIA 1963-86 MSH
IAN DEFAULT ICD10
ICE Cicatricial retinopathy of prematurity ICD9CM
ICE Retinopathy of prematurity NOS ICD9CM
IDENTIFIER_TYPE_ID 1 GARD
INCLUSION_TERM Retrolental fibroplasia ICD10
IS_ACTIVE true GARD
IS_RARE true GARD
IS_SPANISH false GARD
MDA 19990101 MSH
MESH_DEFINITION A bilateral retinopathy occurring in premature infants treated with excessively high concentrations of oxygen, characterized by vascular dilatation, proliferation, and tortuosity, edema, and retinal detachment, with ultimate conversion of the retina into a fibrous mass that can be seen as a dense retrolental membrane. Usually growth of the eye is arrested and may result in microophthalmia, and blindness may occur. (Dorland, 27th ed) NDFRT
MESH_DUI D012178 NDFRT
MESH_NAME Retinopathy of Prematurity NDFRT
MESH_UI M0018966 NDFRT
MMR 20120703 MSH
MN C11.768.836 MSH
MN C16.614.521.731 MSH
MODIFIER_ID 900000000000451002 SNOMEDCT_US
NDFRT_KIND DISEASE_KIND NDFRT
NICHD_Hierarchy_Term Retinopathy of Prematurity NCI
NUI N0000002616 NDFRT
OL use RETINOPATHY OF PREMATURITY to search RETROLENTAL FIBROPLASIA 1966-86 MSH
ORDER_NO 08550 ICD10CM
ORDER_NO 08551 ICD10CM
ORDER_NO 08586 ICD10CM
PM 87; was RETROLENTAL FIBROPLASIA 1963-86 MSH
PRIMARY_PATH 10038933$10008776$10042261$10015919$Retinopathy of prematurity$Choroid and vitreous structural change, deposit and degeneration$Ocular structural change, deposit and degeneration NEC$Eye disorders MDR
PRIMARY_SOC 10015919 MDR
PT_IN_VERSION 10.0 MDR
PT_IN_VERSION 10.1 MDR
PT_IN_VERSION 11.0 MDR
PT_IN_VERSION 11.1 MDR
PT_IN_VERSION 12.0 MDR
PT_IN_VERSION 12.1 MDR
PT_IN_VERSION 13.0 MDR
PT_IN_VERSION 13.1 MDR
PT_IN_VERSION 14.0 MDR
PT_IN_VERSION 14.1 MDR
PT_IN_VERSION 15.0 MDR
PT_IN_VERSION 15.1 MDR
PT_IN_VERSION 16.0 MDR
PT_IN_VERSION 16.1 MDR
PT_IN_VERSION 17.0 MDR
PT_IN_VERSION 17.1 MDR
PT_IN_VERSION 18.0 MDR
PT_IN_VERSION 18.1 MDR
PT_IN_VERSION 19.0 MDR
PT_IN_VERSION 19.1 MDR
PT_IN_VERSION 20.0 MDR
PT_IN_VERSION 20.1 MDR
PT_IN_VERSION 8.0 MDR
PT_IN_VERSION 8.1 MDR
PT_IN_VERSION 9.0 MDR
PT_IN_VERSION 9.1 MDR
RARE_DISEASE_URL http://rarediseases.info.nih.gov/gard/5695/retinopathy-of-prematurity/resources/1 GARD
RXAUI 3231995 RXNORM
RXAUI 3231996 RXNORM
RXAUI 3232042 RXNORM
RXCUI 1026388 RXNORM
SMQ_TERM_ADDVERSION 12.0 MDR
SMQ_TERM_ADDVERSION 14.0 MDR
SMQ_TERM_CAT A MDR
SMQ_TERM_LEVEL 4 MDR
SMQ_TERM_LEVEL 5 MDR
SMQ_TERM_LMVERSION 12.0 MDR
SMQ_TERM_LMVERSION 14.0 MDR
SMQ_TERM_SCOPE 2 MDR
SMQ_TERM_STATUS A MDR
SMQ_TERM_WEIGHT 0 MDR
SNOMED_CID 415297005 NDFRT
SUBSET_MEMBER 447562003~CORRELATIONID~447561005 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPADVICE~ALWAYS H35.1 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPCATEGORYID~447637006 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPGROUP~1 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPPRIORITY~1 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPRULE~TRUE SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPTARGET~H35.1 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~CORRELATIONID~447561005 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~ALWAYS H35.109 | CONSIDER LATERALITY SPECIFICATION SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~IF RETINOPATHY OF PREMATURITY STAGE 1 - DEMARCATION LINE CHOOSE H35.129 | CONSIDER LATERALITY SPECIFICATION | MAP OF SOURCE CONCEPT IS CONTEXT DEPENDENT SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~IF RETINOPATHY OF PREMATURITY STAGE 2 - INTRARETINAL RIDGE CHOOSE H35.139 | CONSIDER LATERALITY SPECIFICATION | MAP OF SOURCE CONCEPT IS CONTEXT DEPENDENT SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~IF RETINOPATHY OF PREMATURITY STAGE 3 - RIDGE WITH EXTRARETINAL FIBROVASCULAR PROLIFERATION CHOOSE H35.149 | CONSIDER LATERALITY SPECIFICATION | MAP OF SOURCE CONCEPT IS CONTEXT DEPENDENT SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~IF RETINOPATHY OF PREMATURITY STAGE 4 - SUBTOTAL RETINAL DETACHMENT CHOOSE H35.159 | CONSIDER LATERALITY SPECIFICATION | MAP OF SOURCE CONCEPT IS CONTEXT DEPENDENT SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~IF RETINOPATHY OF PREMATURITY STAGE 5 - TOTAL RETINAL DETACHMENT CHOOSE H35.169 | CONSIDER LATERALITY SPECIFICATION | MAP OF SOURCE CONCEPT IS CONTEXT DEPENDENT SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPCATEGORYID~447637006 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPCATEGORYID~447639009 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPGROUP~1 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~1 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~2 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~3 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~4 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~5 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~6 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~IFA 408847006 | Retinopathy of prematurity stage 1 - demarcation line | SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~IFA 408848001 | Retinopathy of prematurity stage 2 - intraretinal ridge | SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~IFA 408849009 | Retinopathy of prematurity stage 3 - ridge with extraretinal fibrovascular proliferation | SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~IFA 408850009 | Retinopathy of prematurity stage 4 - subtotal retinal detachment | SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~IFA 408851008 | Retinopathy of prematurity stage 5 - total retinal detachment | SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~OTHERWISE TRUE SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~H35.109 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~H35.129 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~H35.139 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~H35.149 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~H35.159 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~H35.169 SNOMEDCT_US
SUBSET_MEMBER 900000000000497000~MAPTARGET~XUckc SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
TERMUI T036246 MSH
TERMUI T036247 MSH
TH NLM (1966) MSH
TH OMIM (2013) MSH
TH ORD (2010) MSH
TH UNK (19XX) MSH
TYPE_ID 900000000000003001 SNOMEDCT_US
TYPE_ID 900000000000013009 SNOMEDCT_US

Additional Concept Data:  (none)

URL to Bookmark: https://ncim-stage.nci.nih.gov/ncimbrowser/ConceptReport.jsp?dictionary=NCI Metathesaurus&code=C0035344

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