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Kidney Failure (CUI C0035078) Suggest changes to this concept
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Terms & Properties

Concept Unique Identifier (CUI): C0035078

NCI Thesaurus Code: C4376  (see NCI Thesaurus info)

Semantic Type: Disease or Syndrome

NCIt Definition: An acute or chronic condition that is characterized by the inability of the kidneys to adequately filter the blood.

RADLEX Definition: A severe irreversible decline in the ability of kidneys to remove wastes, concentrate urine, and maintain electrolyte balance; blood pressure; and calcium metabolism. Renal failure, either acute (kidney failure, acute) or chronic (kidney failure, chronic), requires hemodialysis. [MeSH]

MSH Definition: A severe irreversible decline in the ability of kidneys to remove wastes, concentrate URINE, and maintain ELECTROLYTE BALANCE; BLOOD PRESSURE; and CALCIUM metabolism.

MEDLINEPLUS Definition: 

Healthy kidneys clean your blood by removing excess fluid, minerals, and wastes. They also make hormones that keep your bones strong and your blood healthy. But if the kidneys are damaged, they don't work properly. Harmful wastes can build up in your body. Your blood pressure may rise. Your body may retain excess fluid and not make enough red blood cells. This is called kidney failure.

If your kidneys fail, you need treatment to replace the work they normally do. The treatment options are dialysis or a kidney transplant. Each treatment has benefits and drawbacks. No matter which treatment you choose, you'll need to make some changes in your life, including how you eat and plan your activities. But with the help of healthcare providers, family, and friends, most people with kidney failure can lead full and active lives.

NIH: National Institute of Diabetes and Digestive and Kidney Diseases

NCI-GLOSS Definition: A condition in which the kidneys stop working and are not able to remove waste and extra water from the blood or keep body chemicals in balance. Acute or severe renal failure happens suddenly (for example, after an injury) and may be treated and cured. Chronic renal failure develops over many years, may be caused by conditions like high blood pressure or diabetes, and cannot be cured. Chronic renal failure may lead to total and long-lasting renal failure, called end-stage renal disease (ESRD). A person in ESRD needs dialysis (the process of cleaning the blood by passing it through a membrane or filter) or a kidney transplant.

NICHD Definition: An acute or chronic condition that is characterized by the inability of the kidneys to adequately filter the blood.

CSP Definition: inability of a kidney to excrete metabolites at normal plasma levels under conditions of normal loading or inability to retain electrolytes under conditions of normal intake.

Synonyms & Abbreviations: (see Synonym Details)
ESRD
Failure kidney
Failure, Kidney
Failure, Renal
Failures, Kidney
Failures, Renal
Kidney Failure [Disease/Finding]
Kidney Failures
kidney failure
Nierenversagen
Renal failure NOS
Renal failure syndrome (disorder)
Renal Failure Syndrome
Renal failure unspecified
Renal failure, unspecified
Renal Failures
renal failure
Renal insufficiency (disorder)
Renal insufficiency syndrome
Renal Insufficiency
RF - Renal failure
Unspecified kidney failure

External Source Codes: 
NCI Thesaurus Code C4376 (see NCI Thesaurus info)

Other Properties: Property Definitions
Name Value Source
ACTIVE 1 SNOMEDCT_US
CASE_SIGNIFICANCE_ID 900000000000017005 SNOMEDCT_US
CASE_SIGNIFICANCE_ID 900000000000020002 SNOMEDCT_US
CHARACTERISTIC_TYPE_ID 900000000000011006 SNOMEDCT_US
Contributing_Source CTRP NCI
Contributing_Source FDA NCI
Contributing_Source MedDRA NCI
Contributing_Source NICHD NCI
CTV3ID X30Io SNOMEDCT_US
CTV3ID XUv31 SNOMEDCT_US
DATE_CREATED 01/27/1999 MEDLINEPLUS
DATE_FIRST_PUBLISHED 2007-01-05 PDQ
DATE_LAST_MODIFIED 2007-01-03 PDQ
DEFINITION_STATUS_ID 900000000000074008 SNOMEDCT_US
DID 1682-2744 CSP
EFFECTIVE_TIME 20020131 SNOMEDCT_US
EFFECTIVE_TIME 20170131 SNOMEDCT_US
EXCLUDES1 acute kidney failure (N17.-) ICD10CM
EXCLUDES1 chronic kidney disease (N18.-) ICD10CM
EXCLUDES1 chronic uremia (N18.9) ICD10CM
EXCLUDES1 extrarenal uremia (R39.2) ICD10CM
EXCLUDES1 prerenal uremia (R39.2) ICD10CM
EXCLUDES1 renal insufficiency (acute) (N28.9) ICD10CM
EXCLUDES1 uremia of newborn (P96.0) ICD10CM
FDA_Table Patient Code (Appendix B) NCI
IAN DEFAULT ICD10
ICE Uremia NOS ICD9CM
INCLUSION_TERM Renal insufficiency NOS ICD10
MESH_DEFINITION A severe irreversible decline in the ability of kidneys to remove wastes, concentrate URINE, and maintain ELECTROLYTE BALANCE; BLOOD PRESSURE; and CALCIUM metabolism. NDFRT
MESH_DUI D051437 NDFRT
MESH_NAME Kidney Failure NDFRT
MESH_UI M0025974 NDFRT
MODIFIER_ID 900000000000451002 SNOMEDCT_US
MP_HEALTH_TOPIC_URL https://www.nlm.nih.gov/medlineplus/kidneyfailure.html MEDLINEPLUS
MP_OTHER_LANGUAGE_URL Arabic https://www.nlm.nih.gov/medlineplus/languages/kidneyfailure.html#Arabic MEDLINEPLUS
MP_OTHER_LANGUAGE_URL Bosnian https://www.nlm.nih.gov/medlineplus/languages/kidneyfailure.html#Bosnian MEDLINEPLUS
MP_OTHER_LANGUAGE_URL Chinese - Simplified https://www.nlm.nih.gov/medlineplus/languages/kidneyfailure.html#Chinese - Simplified MEDLINEPLUS
MP_OTHER_LANGUAGE_URL Chinese - Traditional https://www.nlm.nih.gov/medlineplus/languages/kidneyfailure.html#Chinese - Traditional MEDLINEPLUS
MP_OTHER_LANGUAGE_URL French https://www.nlm.nih.gov/medlineplus/languages/kidneyfailure.html#French MEDLINEPLUS
MP_OTHER_LANGUAGE_URL Hindi https://www.nlm.nih.gov/medlineplus/languages/kidneyfailure.html#Hindi MEDLINEPLUS
MP_OTHER_LANGUAGE_URL Japanese https://www.nlm.nih.gov/medlineplus/languages/kidneyfailure.html#Japanese MEDLINEPLUS
MP_OTHER_LANGUAGE_URL Korean https://www.nlm.nih.gov/medlineplus/languages/kidneyfailure.html#Korean MEDLINEPLUS
MP_OTHER_LANGUAGE_URL Portuguese https://www.nlm.nih.gov/medlineplus/languages/kidneyfailure.html#Portuguese MEDLINEPLUS
MP_OTHER_LANGUAGE_URL Russian https://www.nlm.nih.gov/medlineplus/languages/kidneyfailure.html#Russian MEDLINEPLUS
MP_OTHER_LANGUAGE_URL Somali https://www.nlm.nih.gov/medlineplus/languages/kidneyfailure.html#Somali MEDLINEPLUS
MP_OTHER_LANGUAGE_URL Spanish https://www.nlm.nih.gov/medlineplus/spanish/kidneyfailure.html MEDLINEPLUS
MP_OTHER_LANGUAGE_URL Tagalog https://www.nlm.nih.gov/medlineplus/languages/kidneyfailure.html#Tagalog MEDLINEPLUS
MP_OTHER_LANGUAGE_URL Vietnamese https://www.nlm.nih.gov/medlineplus/languages/kidneyfailure.html#Vietnamese MEDLINEPLUS
MP_PRIMARY_INSTITUTE_URL National Institute of Diabetes and Digestive and Kidney Diseases http://www.niddk.nih.gov/ MEDLINEPLUS
NCI_THESAURUS_CODE C4376 PDQ
NDFRT_KIND DISEASE_KIND NDFRT
NICHD_Hierarchy_Term Renal Failure NCI
NUI N0000003529 NDFRT
ORDER_NO 23346 ICD10CM
ORIG_STY Secondary related condition PDQ
PRIMARY_PATH 10038435$10038443$10038430$10038359$Renal failure$Renal failure and impairment$Renal disorders (excl nephropathies)$Renal and urinary disorders MDR
PRIMARY_SOC 10038359 MDR
PT_IN_VERSION 10.0 MDR
PT_IN_VERSION 10.1 MDR
PT_IN_VERSION 11.0 MDR
PT_IN_VERSION 11.1 MDR
PT_IN_VERSION 12.0 MDR
PT_IN_VERSION 12.1 MDR
PT_IN_VERSION 13.0 MDR
PT_IN_VERSION 13.1 MDR
PT_IN_VERSION 14.0 MDR
PT_IN_VERSION 14.1 MDR
PT_IN_VERSION 15.0 MDR
PT_IN_VERSION 15.1 MDR
PT_IN_VERSION 16.0 MDR
PT_IN_VERSION 16.1 MDR
PT_IN_VERSION 17.0 MDR
PT_IN_VERSION 17.1 MDR
PT_IN_VERSION 18.0 MDR
PT_IN_VERSION 18.1 MDR
PT_IN_VERSION 19.0 MDR
PT_IN_VERSION 19.1 MDR
PT_IN_VERSION 8.0 MDR
PT_IN_VERSION 8.1 MDR
PT_IN_VERSION 9.0 MDR
PT_IN_VERSION 9.1 MDR
RXAUI 3184625 RXNORM
RXAUI 3184626 RXNORM
RXAUI 3231490 RXNORM
RXCUI 1022860 RXNORM
SMQ_TERM_ADDVERSION 11.1 MDR
SMQ_TERM_ADDVERSION 16.0 MDR
SMQ_TERM_ADDVERSION 16.1 MDR
SMQ_TERM_ADDVERSION 19.0 MDR
SMQ_TERM_ADDVERSION 7.1 MDR
SMQ_TERM_ADDVERSION 9.1 MDR
SMQ_TERM_CAT A MDR
SMQ_TERM_CAT B MDR
SMQ_TERM_CAT C MDR
SMQ_TERM_LEVEL 4 MDR
SMQ_TERM_LEVEL 5 MDR
SMQ_TERM_LMVERSION 11.1 MDR
SMQ_TERM_LMVERSION 16.0 MDR
SMQ_TERM_LMVERSION 16.1 MDR
SMQ_TERM_LMVERSION 19.0 MDR
SMQ_TERM_LMVERSION 7.1 MDR
SMQ_TERM_LMVERSION 9.1 MDR
SMQ_TERM_SCOPE 1 MDR
SMQ_TERM_SCOPE 2 MDR
SMQ_TERM_STATUS A MDR
SMQ_TERM_WEIGHT 0 MDR
SNOMED_CID 266553002 NDFRT
SNOMED_CID 42399005 NDFRT
SNOMEDID D7-11010 SNOMEDCT_US
SNOMEDID R0-01459 SNOMEDCT_US
SUBSET_MEMBER 447562003~CORRELATIONID~447561005 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPADVICE~ALWAYS N19 | POSSIBLE REQUIREMENT FOR AN EXTERNAL CAUSE CODE SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPADVICE~ALWAYS N19 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPCATEGORYID~447637006 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPGROUP~1 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPPRIORITY~1 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPRULE~TRUE SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPTARGET~N19 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~CORRELATIONID~447561005 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~ALWAYS N19 | DESCENDANTS NOT EXHAUSTIVELY MAPPED SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~IF AGE AT ONSET OF CLINICAL FINDING BEFORE 29.0 DAYS CHOOSE P96.0 | DESCENDANTS NOT EXHAUSTIVELY MAPPED | MAP OF SOURCE CONCEPT IS CONTEXT DEPENDENT SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPCATEGORYID~447637006 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPCATEGORYID~447639009 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPGROUP~1 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~1 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~2 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~IFA 445518008 | Age at onset of clinical finding (observable entity) | < 29.0 days SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~OTHERWISE TRUE SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~N19 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~P96.0 SNOMEDCT_US
SUBSET_MEMBER 900000000000497000~MAPTARGET~X30Io SNOMEDCT_US
SUBSET_MEMBER 900000000000497000~MAPTARGET~XUv31 SNOMEDCT_US
SUBSET_MEMBER 900000000000498005~MAPTARGET~D7-11010 SNOMEDCT_US
SUBSET_MEMBER 900000000000498005~MAPTARGET~R0-01459 SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
TERMUI T051038 MSH
TERMUI T051039 MSH
TH NLM (1993) MSH
TYPE_ID 900000000000003001 SNOMEDCT_US
TYPE_ID 900000000000013009 SNOMEDCT_US

Additional Concept Data:  (none)

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