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Protein-Losing Enteropathies (CUI C0033680) Suggest changes to this concept
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Terms & Properties

Concept Unique Identifier (CUI): C0033680

Semantic Type: Disease or Syndrome

HPO Definition: Abnormal loss of protein from the digestive tract related to excessive leakage of plasma proteins into the lumen of the gastrointestinal tract. [HPO:probinson]

MSH Definition: Pathological conditions in the INTESTINES that are characterized by the gastrointestinal loss of serum proteins, including SERUM ALBUMIN; IMMUNOGLOBULINS; and at times LYMPHOCYTES. Severe condition can result in HYPOGAMMAGLOBULINEMIA or LYMPHOPENIA. Protein-losing enteropathies are associated with a number of diseases including INTESTINAL LYMPHANGIECTASIS; WHIPPLE'S DISEASE; and NEOPLASMS of the SMALL INTESTINE.

Synonyms & Abbreviations: (see Synonym Details)
Enteropathies, Exudative
Enteropathies, Protein-Losing
Enteropathy, Exudative
ENTEROPATHY, PROTEIN-LOSING
Exudative Enteropathies
Exudative enteropathy (disorder)
exudative enteropathy
PLE - Protein-losing enteropathy
PLE
Protein Losing Enteropathies
Protein Losing Enteropathy
Protein-Losing Enteropathies [Disease/Finding]
Protein-Losing Enteropathies
Protein-losing enteropathy (disorder)
protein-losing enteropathy

External Source Codes:  (none)

Other Properties: Property Definitions
Name Value Source
ACTIVE 1 SNOMEDCT_US
AQL BL CF CI CL CN CO DG DH DI DT EC EH EM EN EP ET GE HI IM ME MI MO NU PA PC PP PS PX RH RT SU TH UR VE VI MSH
CASE_SIGNIFICANCE_ID 900000000000017005 SNOMEDCT_US
CASE_SIGNIFICANCE_ID 900000000000448009 SNOMEDCT_US
CHARACTERISTIC_TYPE_ID 900000000000011006 SNOMEDCT_US
CTV3ID J69y1 SNOMEDCT_US
CTV3ID XU9oC SNOMEDCT_US
DC 1 MSH
DEFINITION_STATUS_ID 900000000000074008 SNOMEDCT_US
DX 19660101 MSH
EFFECTIVE_TIME 20020131 SNOMEDCT_US
FX D000361 MSH
FX D007019 MSH
FX D008231 MSH
HN 66 MSH
HPO_COMMENT Affected individuals may present with peripheral edema, diarrhea with or without bleeding, abdominal pain, and/or weight loss. Protein-losing enteropathy is not a disease but is a manifestation of a number of gastrointestinal diseases and can be related to factors such as lymphatic obstruction, mucosal disease with erosions, ulcerations, or increased mucosal permeability to proteins. HPO
MDA 19990101 MSH
MESH_DEFINITION Pathological conditions in the INTESTINES that are characterized by the gastrointestinal loss of serum proteins, including SERUM ALBUMIN; IMMUNOGLOBULINS; and at times LYMPHOCYTES. Severe condition can result in HYPOGAMMAGLOBULINEMIA or LYMPHOPENIA. Protein-losing enteropathies are associated with a number of diseases including INTESTINAL LYMPHANGIECTASIS; WHIPPLE'S DISEASE; and NEOPLASMS of the SMALL INTESTINE. NDFRT
MESH_DUI D011504 NDFRT
MESH_NAME Protein-Losing Enteropathies NDFRT
MESH_UI M0017886 NDFRT
MIMTYPE 5 OMIM
MIMTYPEMEANING Mendelian phenotype or locus, molecular basis unknown. OMIM
MIMTYPEVALUE perc OMIM
MMR 20120703 MSH
MN C06.405.469.818 MSH
MODIFIER_ID 900000000000451002 SNOMEDCT_US
NDFRT_KIND DISEASE_KIND NDFRT
NUI N0000002505 NDFRT
PM 66 MSH
RXAUI 3154373 RXNORM
RXAUI 3224952 RXNORM
RXAUI 3224953 RXNORM
RXAUI 3224954 RXNORM
RXAUI 5039316 RXNORM
RXCUI 1025484 RXNORM
SNOMED_CID 22542007 NDFRT
SNOMED_CID 66972006 NDFRT
SUBSET_MEMBER 447562003~CORRELATIONID~447561005 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPADVICE~ALWAYS K63.9 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPADVICE~ALWAYS K90.4 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPCATEGORYID~447637006 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPGROUP~1 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPPRIORITY~1 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPRULE~TRUE SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPTARGET~K63.9 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPTARGET~K90.4 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~CORRELATIONID~447561005 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~ALWAYS K90.49 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPCATEGORYID~447637006 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPGROUP~1 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~1 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~TRUE SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~K90.49 SNOMEDCT_US
SUBSET_MEMBER 900000000000497000~MAPTARGET~J69y1 SNOMEDCT_US
SUBSET_MEMBER 900000000000497000~MAPTARGET~XU9oC SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
TERMUI T033993 MSH
TERMUI T033994 MSH
TERMUI T529928 MSH
TERMUI T811839 MSH
TH NLM (1966) MSH
TH NLM (2004) MSH
TH OMIM (2013) MSH
TH UNK (19XX) MSH
TYPE_ID 900000000000003001 SNOMEDCT_US
TYPE_ID 900000000000013009 SNOMEDCT_US

Additional Concept Data:  (none)

URL to Bookmark: https://ncim-stage.nci.nih.gov/ncimbrowser/ConceptReport.jsp?dictionary=NCI Metathesaurus&code=C0033680

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