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| Terms & Properties |
Concept Unique Identifier (CUI): C0033487
NCI Thesaurus Code: C29384 (see NCI Thesaurus info)
Semantic Type: Organic Chemical
Semantic Type: Pharmacologic Substance
NCIt Definition: A hypnotic alkylphenol derivative. Formulated for intravenous induction of sedation and hypnosis during anesthesia, propofol facilitates inhibitory neurotransmission mediated by gamma-aminobutyric acid (GABA). This agent is associated with minimal respiratory depression and has a short half-life with a duration of action of 2 to 10 minutes.
PDQ Definition: A hypnotic alkylphenol derivative. Formulated for intravenous induction of sedation and hypnosis during anesthesia, propofol facilitates inhibitory neurotransmission mediated by gamma-aminobutyric acid (GABA). This agent is associated with minimal respiratory depression and has a short half-life with a duration of action of 2 to 10 minutes. Check for active clinical trials using this agent. (NCI Thesaurus)
MSH Definition: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
Synonyms & Abbreviations: (see Synonym Details)
| 2,6 Diisopropylphenol |
| 2,6-Bis(1-methylethyl)phenol |
| 2,6-Diisopropylphenol |
| Astra Brand of Propofol |
| AstraZeneca Brand of Propofol |
| Diprivan |
| Disoprivan |
| Disoprofol |
| Phenol, 2,6-bis(1-methylethyl)- |
| Product containing propofol (medicinal product) |
| Product containing propofol |
| Propofol (substance) |
| Propofol [Chemical/Ingredient] |
| Propofolum |
| propofol |
| Zeneca Brand of Propofol |
External Source Codes:
| NCI Thesaurus Code | C29384 (see NCI Thesaurus info) |
| CAS Registry Number | 2078-54-8 (see NLM ChemIDplus info) |
| FDA UNII Code | YI7VU623SF |
| NSC Code | 5105 (see NCI DTP info) |
| PDQ Closed Trial Search ID | 461189 |
| PDQ Open Trial Search ID | 461189 (check for NCI PDQ open clinical trial info) |
Other Properties:
| Name | Value | Source |
|---|---|---|
| ACTIVE | 1 | SNOMEDCT_US |
| AQL | AA AD AE AG AI AN BL CF CH CL CS CT EC HI IM IP ME PD PK PO RE SD ST TO TU UR | MSH |
| CASE_SIGNIFICANCE_ID | 900000000000448009 | SNOMEDCT_US |
| CHARACTERISTIC_TYPE_ID | 900000000000011006 | SNOMEDCT_US |
| CHEBI_ID | CHEBI:44915 | NCI |
| Chemical_Formula | C12H18O | NCI |
| Contributing_Source | CTRP | NCI |
| Contributing_Source | FDA | NCI |
| CTV3ID | o15.. | SNOMEDCT_US |
| CTV3ID | XUWw8 | SNOMEDCT_US |
| DATE_FIRST_PUBLISHED | 2005-12-22 | PDQ |
| DATE_LAST_MODIFIED | 2007-07-11 | PDQ |
| DC | 1 | MSH |
| DEFINITION_STATUS_ID | 900000000000074008 | SNOMEDCT_US |
| DX | 19900101 | MSH |
| EFFECTIVE_TIME | 20020131 | SNOMEDCT_US |
| EFFECTIVE_TIME | 20030131 | SNOMEDCT_US |
| FDA_UNII_CODE | YI7VU623SF | DRUGBANK |
| FDA_UNII_CODE | YI7VU623SF | NDFRT |
| FX | D000072736 | MSH |
| HN | 90 | MSH |
| HN | Introduced 2000. | AOD |
| LEVEL | Ingredient | NDFRT |
| LT | TRD | MSH |
| LT | TRD | MTH |
| LT | TRD | PDQ |
| MDA | 19890608 | MSH |
| MESH_DEFINITION | An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS. | NDFRT |
| MESH_DUI | D015742 | NDFRT |
| MESH_NAME | Propofol | NDFRT |
| MESH_UI | M0024130 | NDFRT |
| MMR | 20160701 | MSH |
| MN | D02.455.426.559.389.657.773 | MSH |
| MODIFIER_ID | 900000000000451002 | SNOMEDCT_US |
| NCI_THESAURUS_CODE | C29384 | PDQ |
| NDFRT_KIND | DRUG_KIND | NDFRT |
| NDFRT_KIND | INGREDIENT_KIND | NDFRT |
| NUI | N0000006386 | NDFRT |
| NUI | N0000147620 | NDFRT |
| ORIG_STY | Drug/agent | PDQ |
| PA | D006993 | MSH |
| PA | D018686 | MSH |
| PM | 90 | MSH |
| RN | 0 | MSH |
| RN | YI7VU623SF | MSH |
| RR | 2078-54-8 (Propofol) | MSH |
| RXAUI | 1090300 | RXNORM |
| RXAUI | 2074054 | RXNORM |
| RXAUI | 2597961 | RXNORM |
| RXAUI | 2771847 | RXNORM |
| RXAUI | 281156 | RXNORM |
| RXAUI | 3092336 | RXNORM |
| RXAUI | 3092344 | RXNORM |
| RXAUI | 3148420 | RXNORM |
| RXAUI | 3216635 | RXNORM |
| RXAUI | 3216636 | RXNORM |
| RXAUI | 3219741 | RXNORM |
| RXAUI | 3224227 | RXNORM |
| RXAUI | 3224228 | RXNORM |
| RXAUI | 6378860 | RXNORM |
| RXCUI | 196459 | RXNORM |
| RXCUI | 8782 | RXNORM |
| RXN_BN_CARDINALITY | single | RXNORM |
| SID | APRD01201 | DRUGBANK |
| SID | DB05893 | DRUGBANK |
| SID | EXPT02558 | DRUGBANK |
| SPL_SET_ID | 28d7ba00-f824-4e55-139a-03f509c099db | MTHSPL |
| SPL_SET_ID | 3d382e4e-dab1-47d6-a509-49f5f38bfbfe | MTHSPL |
| SPL_SET_ID | 6f8bebf9-d87b-469a-911a-21135ba841ae | MTHSPL |
| SPL_SET_ID | 7603f1ba-cfbd-4ec5-881a-13f4832c9893 | MTHSPL |
| SPL_SET_ID | 7699dd48-068e-4f74-bb50-c0f6cc531263 | MTHSPL |
| SPL_SET_ID | 9c7679bd-31d1-4a62-b7b5-d0c52be1fccd | MTHSPL |
| SPL_SET_ID | a240bf74-5dee-ab9f-65fc-09565dc32f44 | MTHSPL |
| SPL_SET_ID | C0403897-79F5-4086-94B7-56C0CB7EE65C | MTHSPL |
| SPL_SET_ID | d1ae9e26-ffd6-43df-bbd6-869cdede6afe | MTHSPL |
| SPL_SET_ID | dd28195e-a481-4d7a-b578-488fe37ecc09 | MTHSPL |
| SPL_SET_ID | e3105799-a4b6-f3f4-e6e2-b2b29bbdb538 | MTHSPL |
| SPL_SET_ID | e56dadc5-c771-4eb3-91ca-d3a59fc29eaa | MTHSPL |
| SPL_SET_ID | ea7567c4-4bf9-58f1-1ccb-65d1a1a8c620 | MTHSPL |
| SPL_SET_ID | ee0c3437-614d-4631-a061-257f5f60c70b | MTHSPL |
| SPL_SET_ID | ef14e332-51ac-ea97-3542-9bc92557dbed | MTHSPL |
| SPL_SET_ID | fa93f173-7858-4d88-860e-76ab97e65c2f | MTHSPL |
| SPL_SET_ID | fee3bd4a-ade3-41fa-839a-48e9af69bcf4 | MTHSPL |
| SUBSET_MEMBER | 900000000000497000~MAPTARGET~o15.. | SNOMEDCT_US |
| SUBSET_MEMBER | 900000000000497000~MAPTARGET~XUWw8 | SNOMEDCT_US |
| SUBSET_MEMBER | 900000000000508004~ACCEPTABILITYID~900000000000548007 | SNOMEDCT_US |
| SUBSET_MEMBER | 900000000000508004~ACCEPTABILITYID~900000000000549004 | SNOMEDCT_US |
| SUBSET_MEMBER | 900000000000509007~ACCEPTABILITYID~900000000000548007 | SNOMEDCT_US |
| SUBSET_MEMBER | 900000000000509007~ACCEPTABILITYID~900000000000549004 | SNOMEDCT_US |
| TERMUI | T046692 | MSH |
| TERMUI | T046694 | MSH |
| TERMUI | T046696 | MSH |
| TERMUI | T046697 | MSH |
| TERMUI | T046698 | MSH |
| TERMUI | T619237 | MSH |
| TERMUI | T619238 | MSH |
| TERMUI | T619239 | MSH |
| TERMUI | T619240 | MSH |
| TH | AU | MSH |
| TH | BAN (19XX) | MSH |
| TH | CA | MSH |
| TH | DE | MSH |
| TH | ES | MSH |
| TH | FDA SRS (2014) | MSH |
| TH | FR | MSH |
| TH | INN (19XX) | MSH |
| TH | MX | MSH |
| TH | NLM (1990) | MSH |
| TH | NLM (1996) | MSH |
| TH | NLM (1999) | MSH |
| TH | NLM (2006) | MSH |
| TH | UK | MSH |
| TH | USAN (1984) | MSH |
| TH | USP (19XX) | MSH |
| TH | US | MSH |
| TYPE_ID | 900000000000003001 | SNOMEDCT_US |
| TYPE_ID | 900000000000013009 | SNOMEDCT_US |
| VANDF_RECORD | 50.416^2114^Active/Master | NDFRT |
| VANDF_RECORD | 50.6^2145^Active/Master | NDFRT |
| VUID | 4019500 | NDFRT |
Additional Concept Data: (none)
URL to Bookmark: https://ncim-stage.nci.nih.gov/ncimbrowser/ConceptReport.jsp?dictionary=NCI Metathesaurus&code=C0033487
