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Polycystic Ovary Syndrome (CUI C0032460) Suggest changes to this concept
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Terms & Properties

Concept Unique Identifier (CUI): C0032460

NCI Thesaurus Code: C26862  (see NCI Thesaurus info)

Semantic Type: Disease or Syndrome

NCIt Definition: A disorder that manifests as multiple cysts on the ovaries. It results in hormonal imbalances and leads to irregular and abnormal menstrual periods, excess growth of hair, acne eruptions and obesity.

GARD Definition: Polycystic ovarian syndrome (PCOS) is a health problem that can affect a woman's menstrual cycle, ability to have children, hormones, heart, blood vessels, and appearance. Women with this condition typically have high levels of  hormones called androgens, missed or irregular periods, and many small cysts in their ovaries. The cause of PCOS is unknown, but probably involves a combination of genetic and environmental factors. Treatment for PCOS may involve birth control pills and medications for diabetes and infertility. Medicines called anti-androgens are also used to speed the growth of hair and clear acne. - this information is from GARD/ORDR/NCATS.

MEDLINEPLUS Definition: 

Polycystic ovary syndrome (PCOS) happens when a woman's ovaries or adrenal glands produce more male hormones than normal. One result is that cysts (fluid-filled sacs) develop on the ovaries. Women who are obese are more likely to have polycystic ovary syndrome.

Symptoms of PCOS include:

  • Infertility
  • Pelvic pain
  • Excess hair growth on the face, chest, stomach, thumbs, or toes
  • Baldness or thinning hair
  • Acne, oily skin, or dandruff
  • Patches of thickened dark brown or black skin

Women with PCOS are at higher risk of diabetes, metabolic syndrome, heart disease, and high blood pressure. Medicines can help control the symptoms. Birth control pills help women have normal periods, reduce male hormone levels, and clear acne. Other medicines can reduce hair growth and control blood pressure and cholesterol. There is no cure.

NIH: National Institute of Child Health and Human Development

NCI-GLOSS Definition: A condition marked by infertility, enlarged ovaries, menstrual problems, high levels of male hormones, excess hair on the face and body, acne, and obesity. Women with PCOS have an increased risk of diabetes, high blood pressure, heart disease, and endometrial cancer.

NICHD Definition: A condition of unknown or heterogenous genetic etiology that is characterized by hyperandrogenism and ovarian dysfunction, though the clinical features of the condition may differ between teenage girls and adult women. For teenage girls, the characteristic features generally manifest as persistent, otherwise unexplained hyperandrogenism and reduced or absent ovulation with associated menstrual irregularity, as determined by age- and pubertal stage-appropriate criteria. Additional clinical manifestations include some or all of the following: obesity, insulin resistance/hyperinsulinemia or frank type 2 diabetes mellitus, acanthosis nigricans, hirsutism, and polycystic ovary on ultrasound.

CSP Definition: clinical symptom complex characterized by presence of multiple cysts on the ovaries, oligomenorrhea or amenorrhea, anovulation and regularly associated with excessive amounts of body hair (hirsuitism), excessive body weight, infertility and insulin resistance.

MSH Definition: A complex disorder characterized by infertility, HIRSUTISM; OBESITY; and various menstrual disturbances such as OLIGOMENORRHEA; AMENORRHEA; ANOVULATION. Polycystic ovary syndrome is usually associated with bilateral enlarged ovaries studded with atretic follicles, not with cysts. The term, polycystic ovary, is misleading.

Synonyms & Abbreviations: (see Synonym Details)
BILATERAL POLYCYSTIC OVARIAN SYNDROME
Cystic disease of ovaries
HYPERTHECOSIS, OVARIAN
Multicystic ovaries
Ovarian Degeneration, Sclerocystic
Ovarian Syndrome, Polycystic
Ovary Syndrome, Polycystic
PCO - Polycystic ovaries
PCO1
PCOD - Polycystic ovarian disease
PCOS - Polycystic ovarian syndrome
PCOS1
PCOS
PCO
Polycystic Ovarian Disease
POLYCYSTIC OVARIAN SYNDROME
Polycystic ovaries (disorder)
Polycystic ovaries
polycystic ovary disease
polycystic ovary disorder
Polycystic Ovary Syndrome 1
Polycystic Ovary Syndrome [Disease/Finding]
polycystic ovary syndrome
polycystic ovary
POYCYSTIC OVARIAN SYNDROME
Sclerocystic Ovarian Degeneration
SCLEROCYSTIC OVARIAN DISEASE
Sclerocystic ovary syndrome
Stein Lenventhal syndrome
STEIN LEVENTHAL SYNDROME
STEIN-LEVENTHAL SYNDROME
Syndrome, Polycystic Ovary
Syndrome, Stein-Leventhal

External Source Codes: 
NCI Thesaurus Code C26862 (see NCI Thesaurus info)

Other Properties: Property Definitions
Name Value Source
ACTIVE 1 SNOMEDCT_US
AN non-neoplastic MSH
AQL BL BS CF CH CI CL CN CO DG DH DI DT EC EH EM EN EP ET GE HI IM ME MI MO NU PA PC PP PS PX RH RT SC SE SU TH UL UR VE VI MSH
CASE_SIGNIFICANCE_ID 900000000000017005 SNOMEDCT_US
CASE_SIGNIFICANCE_ID 900000000000020002 SNOMEDCT_US
CHARACTERISTIC_TYPE_ID 900000000000011006 SNOMEDCT_US
Contributing_Source NICHD NCI
CTV3ID XE10l SNOMEDCT_US
DATE_CREATED 11/02/2011 MEDLINEPLUS
DATE_CREATED 2013-01-09T00:04:00 GARD
DATE_LAST_MODIFIED 2013-01-09T00:04:00 GARD
DC 1 MSH
DEFINITION_STATUS_ID 900000000000074008 SNOMEDCT_US
DID 2587-6111 CSP
DID 2587-6155 CSP
DISEASE_IDENTIFIER_ID 5447 GARD
DX 19850101 MSH
EFFECTIVE_TIME 20020131 SNOMEDCT_US
FX D017588 MSH
GENELOCUS ,1,9,p,1,3,.,2, OMIM
GENESYMBOL PCO1 OMIM
GENESYMBOL PCOS1 OMIM
GENESYMBOL PCO OMIM
HAS_GARD_PAGE true GARD
HN 85; was STEIN-LEVENTHAL SYNDROME 1963-84 MSH
IAN DEFAULT ICD10
ICE Isosexual virilization Stein-Leventhal syndrome ICD9CM
IDENTIFIER_TYPE_ID 1 GARD
INCLUSION_TERM Sclerocystic ovary syndrome ICD10
INCLUSION_TERM Stein-Leventhal syndrome ICD10
IS_ACTIVE true GARD
IS_RARE false GARD
IS_SPANISH false GARD
LAST_REVIEW_DATE 2010-01-04T00:00:00 GARD
MDA 19990101 MSH
MESH_DEFINITION A complex disorder characterized by infertility, HIRSUTISM; OBESITY; and various menstrual disturbances such as OLIGOMENORRHEA; AMENORRHEA; ANOVULATION. Polycystic ovary syndrome is usually associated with bilateral enlarged ovaries studded with atretic follicles, not with cysts. The term, polycystic ovary, is misleading. NDFRT
MESH_DUI D011085 NDFRT
MESH_NAME Polycystic Ovary Syndrome NDFRT
MESH_UI M0017165 NDFRT
MIMTYPE 5 OMIM
MIMTYPEMEANING Mendelian phenotype or locus, molecular basis unknown. OMIM
MIMTYPEVALUE perc OMIM
MMR 20120703 MSH
MN C04.182.612.765 MSH
MN C13.351.500.056.630.580.765 MSH
MN C19.391.630.580.765 MSH
MODIFIER_ID 900000000000451002 SNOMEDCT_US
MP_HEALTH_TOPIC_URL https://www.nlm.nih.gov/medlineplus/polycysticovarysyndrome.html MEDLINEPLUS
MP_OTHER_LANGUAGE_URL Spanish https://www.nlm.nih.gov/medlineplus/spanish/polycysticovarysyndrome.html MEDLINEPLUS
MP_PRIMARY_INSTITUTE_URL National Institute of Child Health and Human Development http://www.nichd.nih.gov/ MEDLINEPLUS
NDFRT_KIND DISEASE_KIND NDFRT
NICHD_Hierarchy_Term Polycystic Ovary Syndrome NCI
NUI N0000002452 NDFRT
OL use POLYCYSTIC OVARY SYNDROME to search STEIN-LEVENTHAL SYNDROME 1966-84 MSH
ORDER_NO 04349 ICD10CM
PM 85; was STEIN-LEVENTHAL SYNDROME 1963-84 MSH
PRIMARY_PATH 10036049$10033121$10033283$10038604$Polycystic ovaries$Ovarian and fallopian tube cysts and neoplasms$Ovarian and fallopian tube disorders$Reproductive system and breast disorders MDR
PRIMARY_SOC 10038604 MDR
PT_IN_VERSION 10.0 MDR
PT_IN_VERSION 10.1 MDR
PT_IN_VERSION 11.0 MDR
PT_IN_VERSION 11.1 MDR
PT_IN_VERSION 12.0 MDR
PT_IN_VERSION 12.1 MDR
PT_IN_VERSION 13.0 MDR
PT_IN_VERSION 13.1 MDR
PT_IN_VERSION 14.0 MDR
PT_IN_VERSION 14.1 MDR
PT_IN_VERSION 15.0 MDR
PT_IN_VERSION 15.1 MDR
PT_IN_VERSION 16.0 MDR
PT_IN_VERSION 16.1 MDR
PT_IN_VERSION 17.0 MDR
PT_IN_VERSION 17.1 MDR
PT_IN_VERSION 18.0 MDR
PT_IN_VERSION 18.1 MDR
PT_IN_VERSION 19.0 MDR
PT_IN_VERSION 19.1 MDR
PT_IN_VERSION 8.0 MDR
PT_IN_VERSION 8.1 MDR
PT_IN_VERSION 9.0 MDR
PT_IN_VERSION 9.1 MDR
RARE_DISEASE_URL http://rarediseases.info.nih.gov/gard/7421/polycystic-ovarian-syndrome/resources/1 GARD
RXAUI 3222037 RXNORM
RXAUI 3222038 RXNORM
RXAUI 3236867 RXNORM
RXAUI 3236870 RXNORM
RXAUI 3240263 RXNORM
RXAUI 3606235 RXNORM
RXAUI 5039831 RXNORM
RXCUI 1022507 RXNORM
SID HP:0008644 HPO
SID HP:0008657 HPO
SMQ_TERM_ADDVERSION 10.0 MDR
SMQ_TERM_ADDVERSION 14.1 MDR
SMQ_TERM_CAT A MDR
SMQ_TERM_LEVEL 4 MDR
SMQ_TERM_LEVEL 5 MDR
SMQ_TERM_LMVERSION 14.0 MDR
SMQ_TERM_LMVERSION 14.1 MDR
SMQ_TERM_SCOPE 2 MDR
SMQ_TERM_STATUS A MDR
SMQ_TERM_STATUS I MDR
SMQ_TERM_WEIGHT 0 MDR
SNOMED_CID 69878008 NDFRT
SNOMEDID DB-21500 SNOMEDCT_US
SUBSET_MEMBER 447562003~CORRELATIONID~447561005 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPADVICE~ALWAYS E28.2 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPCATEGORYID~447637006 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPGROUP~1 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPPRIORITY~1 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPRULE~TRUE SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPTARGET~E28.2 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~CORRELATIONID~447561005 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~ALWAYS E28.2 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPCATEGORYID~447637006 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPGROUP~1 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~1 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~TRUE SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~E28.2 SNOMEDCT_US
SUBSET_MEMBER 900000000000497000~MAPTARGET~XE10l SNOMEDCT_US
SUBSET_MEMBER 900000000000498005~MAPTARGET~DB-21500 SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
TERMUI T032596 MSH
TERMUI T032597 MSH
TERMUI T481206 MSH
TERMUI T492063 MSH
TERMUI T757364 MSH
TERMUI T811827 MSH
TH NLM (1966) MSH
TH NLM (2003) MSH
TH NLM (2011) MSH
TH OMIM (2013) MSH
TH UNK (19XX) MSH
TYPE_ID 900000000000003001 SNOMEDCT_US
TYPE_ID 900000000000013009 SNOMEDCT_US

Additional Concept Data:  (none)

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