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Poliomyelitis (CUI C0032371) Suggest changes to this concept
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Terms & Properties

Concept Unique Identifier (CUI): C0032371

NCI Thesaurus Code: C35550  (see NCI Thesaurus info)

Semantic Type: Disease or Syndrome

NCIt Definition: An acute infectious disorder that affects the nervous system. It is caused by the poliovirus. The virus spreads by direct contact, and can be prevented by prophylaxis with the polio vaccine.

GARD Definition: 

Poliomyelitis is a viral disease that can affect nerves and can lead to partial or full paralysis. It is caused by infection with the poliovirus which can be spread by direct person-to-person contact, by contact with infected mucus or phlegm from the nose or mouth, or by contact with infected feces. Since the development of polio vaccine, the incidence of the disease has been greatly reduced. There are three basic patterns of polio infection: subclinical infections, nonparalytic, and paralytic. Approximately 95% of infections are subclinical infections, which may not have symptoms. Clinical poliomyelitis affects the central nervous system (brain and spinal cord) and is divided into nonparalytic and paralytic forms. It may occur after recovery from a subclinical infection. Treatment is aimed at controlling symptoms while the infection runs its course. The prognosis depends on the form of the disease (subclinical, nonparalytic, or paralytic) and the site affected. If the spinal cord and brain are not involved, which is the case more than 90% of the time, complete recovery is likely.

- this information is from GARD/ORDR/NCATS.

NICHD Definition: Inflammation of the spinal cord that is caused by the poliovirus, and that often results in flaccid paralysis.

CSP Definition: acute infectious disease of humans, particularly children, caused by any of three serotypes of human poliovirus; infection is usually limited to the gastrointestinal tract and nasopharynx, and is often asymptomatic; the central nervous system, primarily the spinal cord, may be affected, leading to rapidly progressive paralysis, coarse fasciculation and hyporeflexia; motor neurons are primarily affected and encephalitis may also occur; replicates in the nervous system, and may cause significant neuronal loss, most notably in the spinal cord.

MSH Definition: An acute infectious disease of humans, particularly children, caused by any of three serotypes of human poliovirus (POLIOVIRUS). Usually the infection is limited to the gastrointestinal tract and nasopharynx, and is often asymptomatic. The central nervous system, primarily the spinal cord, may be affected, leading to rapidly progressive paralysis, coarse FASCICULATION and hyporeflexia. Motor neurons are primarily affected. Encephalitis may also occur. The virus replicates in the nervous system, and may cause significant neuronal loss, most notably in the spinal cord. A rare related condition, nonpoliovirus poliomyelitis, may result from infections with nonpoliovirus enteroviruses. (From Adams et al., Principles of Neurology, 6th ed, pp764-5)

Synonyms & Abbreviations: (see Synonym Details)
Ac polio NOS-type NOS
Acute poliomyelitis (disorder)
Acute Poliomyelitis, Epidemic
Acute poliomyelitis, unspecified, poliovirus, unspecified type
Acute poliomyelitis, unspecified
Acute poliomyelitis
Acute unspecified poliomyelitis
Epidemic acute poliomyelitis (disorder)
Epidemic Acute Poliomyelitis
HEINE-MEDIN DISEASE
PM - Poliomyelitis
Polia
Polio acute
Poliomyelitis (acute)
Poliomyelitis [Disease/Finding]
Poliomyelitis acute
Poliomyelitis NOS
Poliomyelitis, Acute
Poliomyelitis, Epidemic Acute
poliomyelitis
Polios
polio

External Source Codes: 
NCI Thesaurus Code C35550 (see NCI Thesaurus info)

Other Properties: Property Definitions
Name Value Source
ACTIVE 1 SNOMEDCT_US
AQL BL CF CI CL CN CO DG DH DI DT EC EH EM EN EP ET GE HI IM ME MI MO NU PA PC PP PS PX RH RT SU TH TM UR VE VI MSH
CASE_SIGNIFICANCE_ID 900000000000017005 SNOMEDCT_US
CASE_SIGNIFICANCE_ID 900000000000448009 SNOMEDCT_US
CHARACTERISTIC_TYPE_ID 900000000000011006 SNOMEDCT_US
Contributing_Source NICHD NCI
CTV3ID XUYUL SNOMEDCT_US
CTV3ID XUYWp SNOMEDCT_US
DATE_CREATED 2013-01-09T00:04:00 GARD
DATE_LAST_MODIFIED 2013-01-09T00:04:00 GARD
DC 1 MSH
DEFINITION_STATUS_ID 900000000000074008 SNOMEDCT_US
DID 2042-5623 CSP
DISEASE_IDENTIFIER_ID 5435 GARD
DX 19660101 MSH
EFFECTIVE_TIME 20030731 SNOMEDCT_US
EXTERNALLY_DEFINED N LNC
FX D016262 MSH
HAS_GARD_PAGE true GARD
IAN DEFAULT ICD10
ICE Infantile paralysis unspecified whether paralytic or nonparalytic; Poliomyelitis (acute) unspecified whether paralytic or nonparalytic {anterior unspecified whether paralytic or nonparalytic; epidemic unspecified whether paralytic or nonparalytic} ICD9CM
ICF The following fifth-digit subclassification is for use with category 045: {0 poliovirus, unspecified type; 1 poliovirus type I; 2 poliovirus type II; 3 poliovirus type III} ICD9CM
IDENTIFIER_TYPE_ID 1 GARD
IS_ACTIVE true GARD
IS_RARE true GARD
IS_SPANISH false GARD
LAST_REVIEW_DATE 2009-01-23T00:00:00 GARD
MDA 19990101 MSH
MESH_DEFINITION An acute infectious disease of humans, particularly children, caused by any of three serotypes of human poliovirus (POLIOVIRUS). Usually the infection is limited to the gastrointestinal tract and nasopharynx, and is often asymptomatic. The central nervous system, primarily the spinal cord, may be affected, leading to rapidly progressive paralysis, coarse FASCICULATION and hyporeflexia. Motor neurons are primarily affected. Encephalitis may also occur. The virus replicates in the nervous system, and may cause significant neuronal loss, most notably in the spinal cord. A rare related condition, nonpoliovirus poliomyelitis, may result from infections with nonpoliovirus enteroviruses. (From Adams et al., Principles of Neurology, 6th ed, pp764-5) NDFRT
MESH_DUI D011051 NDFRT
MESH_NAME Poliomyelitis NDFRT
MESH_UI M0017112 NDFRT
MMR 20150623 MSH
MN C02.782.687.359.764 MSH
MN C10.228.228.618.750 MSH
MN C10.228.854.525.850 MSH
MN C10.668.864 MSH
MODIFIER_ID 900000000000451002 SNOMEDCT_US
NDFRT_KIND DISEASE_KIND NDFRT
NICHD_Hierarchy_Term Acute Poliomyelitis NCI
NUI N0000002449 NDFRT
ORDER_NO 00592 ICD10CM
ORDER_NO 00600 ICD10CM
PRIMARY_PATH 10036012$10036017$10047438$10021881$Poliomyelitis$Poliomyelitis viral infections$Viral infectious disorders$Infections and infestations MDR
PRIMARY_SOC 10021881 MDR
PT_IN_VERSION 10.0 MDR
PT_IN_VERSION 10.1 MDR
PT_IN_VERSION 11.0 MDR
PT_IN_VERSION 11.1 MDR
PT_IN_VERSION 12.0 MDR
PT_IN_VERSION 12.1 MDR
PT_IN_VERSION 13.0 MDR
PT_IN_VERSION 13.1 MDR
PT_IN_VERSION 14.0 MDR
PT_IN_VERSION 14.1 MDR
PT_IN_VERSION 15.0 MDR
PT_IN_VERSION 15.1 MDR
PT_IN_VERSION 16.0 MDR
PT_IN_VERSION 16.1 MDR
PT_IN_VERSION 17.0 MDR
PT_IN_VERSION 17.1 MDR
PT_IN_VERSION 18.0 MDR
PT_IN_VERSION 18.1 MDR
PT_IN_VERSION 19.0 MDR
PT_IN_VERSION 19.1 MDR
PT_IN_VERSION 20.0 MDR
PT_IN_VERSION 20.1 MDR
PT_IN_VERSION 8.0 MDR
PT_IN_VERSION 8.1 MDR
PT_IN_VERSION 9.0 MDR
PT_IN_VERSION 9.1 MDR
RARE_DISEASE_URL http://rarediseases.info.nih.gov/gard/7413/poliomyelitis/resources/1 GARD
RXAUI 3154654 RXNORM
RXAUI 3221844 RXNORM
RXAUI 3221849 RXNORM
RXAUI 3221850 RXNORM
RXAUI 3221851 RXNORM
RXCUI 1023408 RXNORM
SNOMED_CID 398102009 NDFRT
SNOMED_CID 398256009 NDFRT
SOS Excludes: late effects of acute poliomyelitis (138) ICD9CM
SUBSET_MEMBER 447562003~CORRELATIONID~447561005 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPADVICE~ALWAYS A80.9 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPCATEGORYID~447637006 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPGROUP~1 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPPRIORITY~1 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPRULE~TRUE SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPTARGET~A80.9 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~CORRELATIONID~447561005 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~ALWAYS A80.9 | DESCENDANTS NOT EXHAUSTIVELY MAPPED SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~ALWAYS A80.9 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPCATEGORYID~447637006 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPGROUP~1 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~1 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~TRUE SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~A80.9 SNOMEDCT_US
SUBSET_MEMBER 900000000000497000~MAPTARGET~XUYUL SNOMEDCT_US
SUBSET_MEMBER 900000000000497000~MAPTARGET~XUYWp SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
TERMUI T032487 MSH
TERMUI T032488 MSH
TERMUI T370009 MSH
TERMUI T370014 MSH
TH BIOETHICS (1977) MSH
TH NLM (1998) MSH
TH NLM (2000) MSH
TH POPLINE (1994) MSH
TYPE_ID 900000000000003001 SNOMEDCT_US
TYPE_ID 900000000000013009 SNOMEDCT_US

Additional Concept Data:  (none)

URL to Bookmark: https://ncim-stage.nci.nih.gov/ncimbrowser/ConceptReport.jsp?dictionary=NCI Metathesaurus&code=C0032371

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