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Peptic Ulcer (CUI C0030920) Suggest changes to this concept
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Terms & Properties

Concept Unique Identifier (CUI): C0030920

NCI Thesaurus Code: C3318  (see NCI Thesaurus info)

Semantic Type: Disease or Syndrome

NCIt Definition: A mucosal erosion that occurs in the esophagus, stomach or duodenum. Symptoms can include abdominal pain, nausea and vomiting, and bleeding.

RADLEX Definition: Ulcer that occurs in the regions of the gastrointestinal tract which come into contact with gastric juice containing pepsin and gastric acid. It occurs when there are defects in the mucosa barrier. The common forms of peptic ulcers are associated with helicobacter pylori and the consumption of nonsteroidal anti-inflammatory drugs (nsaids). [MeSH]

HPO Definition: An ulcer of the gastrointestinal tract. [HPO:probinson]

MEDLINEPLUS Definition: 

A peptic ulcer is a sore in the lining of your stomach or your duodenum, the first part of your small intestine. A burning stomach pain is the most common symptom. The pain

  • Starts between meals or during the night
  • Briefly stops if you eat or take antacids
  • Lasts for minutes to hours
  • Comes and goes for several days or weeks

Peptic ulcers happen when the acids that help you digest food damage the walls of the stomach or duodenum. The most common cause is infection with a bacterium called Helicobacter pylori. Another cause is the long-term use of nonsteroidal anti-inflammatory medicines (NSAIDs) such as aspirin and ibuprofen. Stress and spicy foods do not cause ulcers, but can make them worse.

To see if you have an H. pylori infection, your doctor will test your blood, breath, or stool. Your doctor also may look inside your stomach and duodenum by doing an endoscopy or x-ray.

Peptic ulcers will get worse if not treated. Treatment may include medicines to reduce stomach acids or antibiotics to kill H. pylori. Antacids and milk can't heal peptic ulcers. Not smoking and avoiding alcohol can help. You may need surgery if your ulcers don't heal.

NIH: National Institute of Diabetes and Digestive and Kidney Diseases

NCI-GLOSS Definition: A break in the lining of the lower part of the esophagus, the stomach, or the upper part of the small intestine. Peptic ulcers form when cells on the surface of the lining become inflamed and die. They are usually caused by Helicobacter pylori bacteria and by certain medicines, such as aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs). Peptic ulcers may be linked to cancer and other diseases.

NICHD Definition: A mucosal injury that occurs in the stomach or duodenum.

CSP Definition: local defect produced by the sloughing of inflammatory necrotic tissue that occurs in the regions of the gastrointestinal tract which come into contact with gastric juice; occurs when there are defects in the mucosa barrier; common forms of peptic ulcers are associated with Helicobacter pylori and the consumption of nonsteroidal antiinflammatory drugs.

MSH Definition: Ulcer that occurs in the regions of the GASTROINTESTINAL TRACT which come into contact with GASTRIC JUICE containing PEPSIN and GASTRIC ACID. It occurs when there are defects in the MUCOSA barrier. The common forms of peptic ulcers are associated with HELICOBACTER PYLORI and the consumption of nonsteroidal anti-inflammatory drugs (NSAIDS).

Synonyms & Abbreviations: (see Synonym Details)
Gastroduodenal Ulcers
gastroduodenal ulcer
GDU
Peptic ulcer (disorder)
Peptic Ulcer [Disease/Finding]
PEPTIC ULCER DISEASE
PEPTIC ULCER SYNDROME
Peptic ulcer, site unspecified
Peptic ulceration
Peptic Ulcers
peptic ulcer
Peptisches Ulkus
PU - Peptic ulcer
PUD - Peptic ulcer disease
PUD
SYNDROME PEPTIC ULCER
ULCER GASTRODUODENAL
ULCER PEPTIC
ULCER SYNDROME PEPTIC
Ulcer, Gastroduodenal
Ulcer, Peptic
Ulcers, Gastroduodenal
Ulcers, Peptic

External Source Codes: 
NCI Thesaurus Code C3318 (see NCI Thesaurus info)

Other Properties: Property Definitions
Name Value Source
ACTIVE 1 SNOMEDCT_US
AN prefer specifics STOMACH ULCER or DUODENAL ULCER; stress ulcer: coordinate with STRESS, PHYSIOLOGICAL or STRESS, PSYCHOLOGICAL MSH
AQL BL CF CI CL CN CO DG DH DI DT EC EH EM EN EP ET GE HI IM ME MI MO NU PA PC PP PS PX RH RT SU TH UR VE VI MSH
CASE_SIGNIFICANCE_ID 900000000000017005 SNOMEDCT_US
CASE_SIGNIFICANCE_ID 900000000000448009 SNOMEDCT_US
Contributing_Source MedDRA NCI
Contributing_Source NICHD NCI
CTV3ID XM0BZ SNOMEDCT_US
DATE_CREATED 02/19/1999 MEDLINEPLUS
DATE_CREATED 2008-03-18T09:14:00Z HPO
DC 1 MSH
DEFINITION_STATUS_ID 900000000000074008 SNOMEDCT_US
DID 1248-6649 CSP
DX 19600101 MSH
EFFECTIVE_TIME 20020131 SNOMEDCT_US
EXCLUDES1 peptic ulcer of newborn (P78.82) ICD10CM
FX D000897 MSH
FX D005743 MSH
FX D010438 MSH
FX D015043 MSH
HN MARGINAL ULCER was heading 1964-96 (see under PEPTIC ULCER 1964-90) MSH
HPO_COMMENT A peptic ulcer is defined as an erosion of the mucosa of the gastrointestinal tract, and can occur as esophageal ulcer, gastric ulcer, duodenal ulcer, and Meckel's Diverticulum ulcer. HPO
IAN DEFAULT ICD10
ICA Use additional E code to identify drug, if drug-induced ICD9CM
ICF The following fifth-digit subclassification is for use with category 533: {0 without mention of obstruction; 1 with obstruction} ICD9CM
INCLUSION_TERM gastroduodenal ulcer NOS ICD10
INCLUSION_TERM peptic ulcer NOS ICD10
MDA 19990101 MSH
MESH_DEFINITION Ulcer that occurs in the regions of the GASTROINTESTINAL TRACT which come into contact with GASTRIC JUICE containing PEPSIN and GASTRIC ACID. It occurs when there are defects in the MUCOSA barrier. The common forms of peptic ulcers are associated with HELICOBACTER PYLORI and the consumption of nonsteroidal anti-inflammatory drugs (NSAIDS). NDFRT
MESH_DUI D010437 NDFRT
MESH_NAME Peptic Ulcer NDFRT
MESH_UI M0016211 NDFRT
MMR 20150625 MSH
MN C06.405.469.275.800 MSH
MN C06.405.748.586 MSH
MP_HEALTH_TOPIC_URL https://www.nlm.nih.gov/medlineplus/pepticulcer.html MEDLINEPLUS
MP_OTHER_LANGUAGE_URL Chinese - Simplified https://www.nlm.nih.gov/medlineplus/languages/pepticulcer.html#Chinese - Simplified MEDLINEPLUS
MP_OTHER_LANGUAGE_URL Chinese - Traditional https://www.nlm.nih.gov/medlineplus/languages/pepticulcer.html#Chinese - Traditional MEDLINEPLUS
MP_OTHER_LANGUAGE_URL Spanish https://www.nlm.nih.gov/medlineplus/spanish/pepticulcer.html MEDLINEPLUS
MP_PRIMARY_INSTITUTE_URL National Institute of Diabetes and Digestive and Kidney Diseases http://www.niddk.nih.gov/ MEDLINEPLUS
NDFRT_KIND DISEASE_KIND NDFRT
NICHD_Hierarchy_Term Peptic Ulcer NCI
NUI N0000002351 NDFRT
ORDER_NO 13091 ICD10CM
PM MARGINAL ULCER was heading 1964-96 (see under PEPTIC ULCER 1964-90) MSH
PRIMARY_PATH 10017886$10013862$10018027$10017947$Gastroduodenal ulcer$Duodenal ulcers and perforation$Gastrointestinal ulceration and perforation$Gastrointestinal disorders MDR
PRIMARY_PATH 10034341$10034371$10018027$10017947$Peptic ulcer$Peptic ulcers and perforation$Gastrointestinal ulceration and perforation$Gastrointestinal disorders MDR
PRIMARY_SOC 10017947 MDR
PT_IN_VERSION 10.0 MDR
PT_IN_VERSION 10.1 MDR
PT_IN_VERSION 11.0 MDR
PT_IN_VERSION 11.1 MDR
PT_IN_VERSION 12.0 MDR
PT_IN_VERSION 12.1 MDR
PT_IN_VERSION 13.0 MDR
PT_IN_VERSION 13.1 MDR
PT_IN_VERSION 14.0 MDR
PT_IN_VERSION 14.1 MDR
PT_IN_VERSION 15.0 MDR
PT_IN_VERSION 15.1 MDR
PT_IN_VERSION 16.0 MDR
PT_IN_VERSION 16.1 MDR
PT_IN_VERSION 17.0 MDR
PT_IN_VERSION 17.1 MDR
PT_IN_VERSION 18.0 MDR
PT_IN_VERSION 18.1 MDR
PT_IN_VERSION 19.0 MDR
PT_IN_VERSION 19.1 MDR
PT_IN_VERSION 20.0 MDR
PT_IN_VERSION 20.1 MDR
PT_IN_VERSION 8.0 MDR
PT_IN_VERSION 8.1 MDR
PT_IN_VERSION 9.0 MDR
PT_IN_VERSION 9.1 MDR
RXAUI 3164912 RXNORM
RXAUI 3218843 RXNORM
RXAUI 3218850 RXNORM
RXCUI 1024813 RXNORM
SMQ_TERM_ADDVERSION 10.1 MDR
SMQ_TERM_CAT A MDR
SMQ_TERM_LEVEL 4 MDR
SMQ_TERM_LEVEL 5 MDR
SMQ_TERM_LMVERSION 13.0 MDR
SMQ_TERM_SCOPE 2 MDR
SMQ_TERM_STATUS A MDR
SMQ_TERM_WEIGHT 0 MDR
SNOMED_CID 13200003 NDFRT
SNOMED_CID 196697002 NDFRT
SNOMED_CID 266437002 NDFRT
SOS Excludes: peptic ulcer: {duodenal (532.0-532.9); gastric (531.0-531.9)} ICD9CM
SOS Includes: gastroduodenal ulcer NOS; peptic ulcer NOS; stress ulcer NOS ICD9CM
SUBSET_MEMBER 447562003~CORRELATIONID~447561005 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPADVICE~ALWAYS K27.9 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPCATEGORYID~447637006 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPGROUP~1 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPPRIORITY~1 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPRULE~TRUE SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPTARGET~K27.9 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~CORRELATIONID~447561005 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~ALWAYS K27.9 | CONSIDER ADDITIONAL CODE TO IDENTIFY SPECIFIC CONDITION OR DISEASE | DESCENDANTS NOT EXHAUSTIVELY MAPPED SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~IF AGE AT ONSET OF CLINICAL FINDING BEFORE 29.0 DAYS CHOOSE P78.82 | DESCENDANTS NOT EXHAUSTIVELY MAPPED | MAP OF SOURCE CONCEPT IS CONTEXT DEPENDENT SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPCATEGORYID~447637006 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPCATEGORYID~447639009 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPGROUP~1 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~1 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~2 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~IFA 445518008 | Age at onset of clinical finding (observable entity) | < 29.0 days SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~OTHERWISE TRUE SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~K27.9 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~P78.82 SNOMEDCT_US
SUBSET_MEMBER 900000000000497000~MAPTARGET~XM0BZ SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
TERMUI T030850 MSH
TERMUI T030851 MSH
TH NLM (1966) MSH
TH UNK (19XX) MSH
TYPE_ID 900000000000003001 SNOMEDCT_US
TYPE_ID 900000000000013009 SNOMEDCT_US
USE_ADDITIONAL alcohol abuse and dependence (F10.-) ICD10CM
USE_ADDITIONAL code to identify: ICD10CM

Additional Concept Data:  (none)

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