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Pentobarbital (CUI C0030883) Suggest changes to this concept
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Terms & Properties

Concept Unique Identifier (CUI): C0030883

NCI Thesaurus Code: C61885  (see NCI Thesaurus info)

Semantic Type: Organic Chemical

Semantic Type: Pharmacologic Substance

CSP Definition: short to intermediate acting barbiturate used as a sedative and hypnotic; the sodium salt is also used as an anticonvulsant, as a preanesthetic and as an adjunct to anesthesia.

MSH Definition: A short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) agent and is usually given orally. It is prescribed more frequently for sleep induction than for sedation but, like similar agents, may lose its effectiveness by the second week of continued administration. (From AMA Drug Evaluations Annual, 1994, p236)

Synonyms & Abbreviations: (see Synonym Details)
2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-ethyl-5-(1-methylbutyl)-
5-Ethyl-5-(1-methyl-butyl)-pyrimidine-2,4,6-trione
5-Ethyl-5-(1-methylbutyl)-2,4,6(1H,3H,5H)-pyrimidinetrione
Mebubarbital
Pentobarbital (substance)
Pentobarbital [Chemical/Ingredient]
pentobarbital
Pentobarbitone
Product containing pentobarbital (medicinal product)
Product containing pentobarbital

External Source Codes: 
NCI Thesaurus Code C61885 (see NCI Thesaurus info)
CAS Registry Number 76-74-4 (see NLM ChemIDplus info)
FDA UNII Code I4744080IR

Other Properties: Property Definitions
Name Value Source
ACTIVE 1 SNOMEDCT_US
AQL AA AD AE AG AI AN BL CF CH CL CS CT EC HI IM IP ME PD PK PO RE SD ST TO TU UR MSH
CASE_SIGNIFICANCE_ID 900000000000448009 SNOMEDCT_US
CHARACTERISTIC_TYPE_ID 900000000000011006 SNOMEDCT_US
CHEBI_ID CHEBI:7983 NCI
Chemical_Formula C11H18N2O3 NCI
Contributing_Source FDA NCI
CTV3ID XUBvY SNOMEDCT_US
CTV3ID XUVzP SNOMEDCT_US
DC 1 MSH
DEFINITION_STATUS_ID 900000000000074008 SNOMEDCT_US
DID 2517-5722 CSP
DX 19660101 MSH
EFFECTIVE_TIME 20020131 SNOMEDCT_US
EFFECTIVE_TIME 20020731 SNOMEDCT_US
FDA_UNII_CODE I4744080IR DRUGBANK
FDA_UNII_CODE I4744080IR NDFRT
LEVEL Ingredient NDFRT
MDA 19990101 MSH
MESH_DEFINITION A short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) agent and is usually given orally. It is prescribed more frequently for sleep induction than for sedation but, like similar agents, may lose its effectiveness by the second week of continued administration. (From AMA Drug Evaluations Annual, 1994, p236) NDFRT
MESH_DUI D010424 NDFRT
MESH_NAME Pentobarbital NDFRT
MESH_UI M0016182 NDFRT
MMR 20160531 MSH
MN D03.383.742.698.253.593 MSH
MODIFIER_ID 900000000000451002 SNOMEDCT_US
NDFRT_KIND DRUG_KIND NDFRT
NDFRT_KIND INGREDIENT_KIND NDFRT
NUI N0000005726 NDFRT
NUI N0000146838 NDFRT
PA D000759 MSH
PA D006993 MSH
PA D018757 MSH
RN I4744080IR MSH
RR 57-33-0 (mono-Na salt) MSH
RR 76-74-4 (Pentobarbital) MSH
RR NJJ0475N0S MSH
RXAUI 2072879 RXNORM
RXAUI 258511 RXNORM
RXAUI 3092257 RXNORM
RXAUI 3196961 RXNORM
RXAUI 3212968 RXNORM
RXAUI 3212969 RXNORM
RXAUI 3218785 RXNORM
RXAUI 3218788 RXNORM
RXAUI 3218790 RXNORM
RXAUI 3733441 RXNORM
RXAUI 6395805 RXNORM
RXAUI 6396392 RXNORM
RXAUI 6401337 RXNORM
RXCUI 8004 RXNORM
SID APRD01174 DRUGBANK
SOS A short-acting, quick-onset barbiturate. AOD
SPL_SET_ID 0da20b0f-dda7-47cb-917f-1d0002f0bcd7 MTHSPL
SPL_SET_ID 2ead4603-a8d5-47c3-8074-8433ba619845 MTHSPL
SPL_SET_ID 434abd98-e76f-4d42-9ba0-d9cd96d84b14 MTHSPL
SPL_SET_ID 4c5d09ad-9bd8-4cdd-ba92-e7f34b265d7d MTHSPL
SPL_SET_ID 4fd5c64f-8560-4459-b0a5-92db95de4e74 MTHSPL
SPL_SET_ID 5bde2b0d-febd-4953-a558-da6b5b110592 MTHSPL
SPL_SET_ID 5c380ab0-4386-48b6-80ab-ca594b23bc74 MTHSPL
SPL_SET_ID 659ae116-430e-4ae0-ab63-7293b196259d MTHSPL
SPL_SET_ID 9e65cc4e-2faa-4652-9bf7-45688b873b5a MTHSPL
SPL_SET_ID b65890b8-ab5a-45b4-8dce-4f3904e5078c MTHSPL
SPL_SET_ID c647a5cc-f754-41cf-8f81-766460aded47 MTHSPL
SPL_SET_ID c885b1d9-db06-47fb-bdb0-4015e06ce08b MTHSPL
SUBSET_MEMBER 900000000000497000~MAPTARGET~XUBvY SNOMEDCT_US
SUBSET_MEMBER 900000000000497000~MAPTARGET~XUVzP SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
TERMUI T030783 MSH
TERMUI T030784 MSH
TERMUI T030785 MSH
TH BAN (19XX) MSH
TH FDA SRS (2014) MSH
TH INN (19XX) MSH
TH UNK (19XX) MSH
TH USP (19XX) MSH
TYPE_ID 900000000000003001 SNOMEDCT_US
TYPE_ID 900000000000013009 SNOMEDCT_US
VANDF_RECORD 50.416^1114^Active/Master NDFRT
VANDF_RECORD 50.6^363^Active/Master NDFRT
VUID 4018516 NDFRT

Additional Concept Data:  (none)

URL to Bookmark: https://ncim-stage.nci.nih.gov/ncimbrowser/ConceptReport.jsp?dictionary=NCI Metathesaurus&code=C0030883

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