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Oxytocin (CUI C0030095) Suggest changes to this concept
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Terms & Properties

Concept Unique Identifier (CUI): C0030095

NCI Thesaurus Code: C2283  (see NCI Thesaurus info)

Semantic Type: Pharmacologic Substance

Semantic Type: Amino Acid, Peptide, or Protein

Semantic Type: Hormone

NCIt Definition: Oxytocin (9 aa, ~1 kDa) is encoded by the human OXT gene. This protein plays a role in smooth muscle contraction in both the mammary gland and uterus. Oxytocin also may also be involved in maternal-newborn bonding, cognition and many other psychological and physiological processes.

CSP Definition: peptide hormone produced by the posterior lobe of the pituitary gland that induces contraction of the smooth muscle of the uterus and the myoepithelial cells of the mammary gland.

MSH Definition: A nonapeptide hormone released from the neurohypophysis (PITUITARY GLAND, POSTERIOR). It differs from VASOPRESSIN by two amino acids at residues 3 and 8. Oxytocin acts on SMOOTH MUSCLE CELLS, such as causing UTERINE CONTRACTIONS and MILK EJECTION.

Synonyms & Abbreviations: (see Synonym Details)
1-({(4R,7S,10S,13S,16S,19R)-19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-16-(4-hydroxybenzyl)-13-[(1S)-1-methylpropyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl}carbonyl)-L-prolyl-L-leucylglycinamide
3-Isoleucine-8-Leucine Vasopressin
CYIQNCPLG-NH2
Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Leu-Gly-NH2, cyclic 1-6 disulfide
Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Leu-Gly-NH2
Ocytocin
OXT
Oxytocin (substance)
Oxytocin [Chemical/Ingredient]
oxytocin
Product containing oxytocin (medicinal product)
Product containing oxytocin
Vasporessin, 3-Isoleucine-8-Leucine

External Source Codes: 
NCI Thesaurus Code C2283 (see NCI Thesaurus info)
CAS Registry Number 50-56-6 (see NLM ChemIDplus info)
OMIM Number 167050 (see OMIM info)
Swiss Prot P01178 (see UniProt/Swiss-Prot info)

Other Properties: Property Definitions
Name Value Source
ACTIVE 1 SNOMEDCT_US
AQL AA AD AE AG AI AN BI BL CF CH CL CS CT DE DF EC GE HI IM IP ME PD PH PK PO RE SD SE ST TO TU UR MSH
AUTHORITY Gray's 38th ed:1886 FMA
CASE_SIGNIFICANCE_ID 900000000000448009 SNOMEDCT_US
CHARACTERISTIC_TYPE_ID 900000000000011006 SNOMEDCT_US
CHEBI_ID CHEBI:7872 NCI
Contributing_Source CTRP NCI
CTV3ID g15.. SNOMEDCT_US
CTV3ID X80G9 SNOMEDCT_US
DC 1 MSH
DEFINITION_STATUS_ID 900000000000074008 SNOMEDCT_US
DID 2334-5056 CSP
DX 19600101 MSH
EFFECTIVE_TIME 20020131 SNOMEDCT_US
FDA_UNII_CODE 1JQS135EYN DRUGBANK
FDA_UNII_CODE 1JQS135EYN NDFRT
FX D018045 MSH
HN ALPHA-HYPOPHAMINE was see OXYTOCIN 1977-93; ISOLEUCYL, LEUCYL VASOPRESSIN; VASOPRESSIN, ISOLEUCYL-LEUCYL; VASOTOCIN, LEUCYL, & 3-ISOLEUCINE,8-LEUCINE VASOPRESSIN were see OXYTOCIN 1983-93 MSH
LEVEL Ingredient NDFRT
MDA 19990101 MSH
MESH_DEFINITION A nonapeptide hormone released from the neurohypophysis (PITUITARY GLAND, POSTERIOR). It differs from VASOPRESSIN by two amino acids at residues 3 and 8. Oxytocin acts on SMOOTH MUSCLE CELLS, such as causing UTERINE CONTRACTIONS and MILK EJECTION. NDFRT
MESH_DUI D010121 NDFRT
MESH_NAME Oxytocin NDFRT
MESH_UI M0015703 NDFRT
MMR 20080708 MSH
MN D06.472.699.631.692.433 MSH
MN D12.644.548.691.692.433 MSH
MODIFIER_ID 900000000000451002 SNOMEDCT_US
NDFRT_KIND DRUG_KIND NDFRT
NDFRT_KIND INGREDIENT_KIND NDFRT
NUI N0000006473 NDFRT
NUI N0000146381 NDFRT
OL use OXYTOCIN to search ALPHA-HYPOPHAMINE 1977-93 & ISOLEUCYL, LEUCYL VASOPRESSIN; VASOPRESSIN, ISOLEUCYL-LEUCYL; VASOTOCIN, LEUCYL, & 3-ISOLEUCINE,8-LEUCINE VASOPRESSIN 1983-93 MSH
PA D010120 MSH
PM ALPHA-HYPOPHAMINE was see OXYTOCIN 1977-93; ISOLEUCYL, LEUCYL VASOPRESSIN; VASOPRESSIN, ISOLEUCYL-LEUCYL; VASOTOCIN, LEUCYL, & 3-ISOLEUCINE,8-LEUCINE VASOPRESSIN were see OXYTOCIN 1983-93 MSH
RN 50-56-6 MSH
RXAUI 2072690 RXNORM
RXAUI 252889 RXNORM
RXAUI 2600181 RXNORM
RXAUI 2981274 RXNORM
RXAUI 3027614 RXNORM
RXAUI 3136921 RXNORM
RXAUI 3209543 RXNORM
RXAUI 3209544 RXNORM
RXAUI 3209835 RXNORM
RXAUI 3211586 RXNORM
RXAUI 3211590 RXNORM
RXCUI 7824 RXNORM
SID BIOD00016 DRUGBANK
SID BTD00016 DRUGBANK
SPL_SET_ID 03dc86d3-575f-4c65-b06d-2613efbcd943 MTHSPL
SPL_SET_ID 06aa4d89-e7a3-417b-bb5e-20ff7058f529 MTHSPL
SPL_SET_ID 10e46b39-7903-4390-b72d-865291245b4c MTHSPL
SPL_SET_ID 1F7D5370-94D6-4BE4-9FB5-990DC924C815 MTHSPL
SPL_SET_ID 29aa28ea-36ef-431c-af1d-4aeec4c0e82a MTHSPL
SPL_SET_ID 32ab2505-9bb7-49d6-af24-ec95c8edfa8b MTHSPL
SPL_SET_ID 447c07c9-5343-4370-b046-5725a7e45398 MTHSPL
SPL_SET_ID 48d3f634-c7f4-48d4-895a-9ef77456cf49 MTHSPL
SPL_SET_ID 4cdbf233-28db-4697-9787-85366ff19bc6 MTHSPL
SPL_SET_ID 6d4b2c25-2e5d-49b5-93bc-2ae8a20916d1 MTHSPL
SPL_SET_ID 6d7d1280-f286-4f39-89f3-2b96571810e6 MTHSPL
SPL_SET_ID 736b2590-79e8-4bd0-ab54-84ff7e29a030 MTHSPL
SPL_SET_ID 7554cc4d-8d27-453d-9dcc-6311fc4f1b27 MTHSPL
SPL_SET_ID 89156ba1-931f-4f3f-ab8a-b1b63e9e4c63 MTHSPL
SPL_SET_ID 8fbd0773-6645-4235-9ef2-56edf9c7fb83 MTHSPL
SPL_SET_ID 969d5b35-0add-4c23-9605-6a5b6ab65c95 MTHSPL
SPL_SET_ID 97113a71-c02e-41b7-950b-6d4ebe5e7156 MTHSPL
SPL_SET_ID 9e16a32c-94dd-4738-869f-847a58b3d996 MTHSPL
SPL_SET_ID a93b13fc-bebe-4669-befd-ab515416c203 MTHSPL
SPL_SET_ID a9b62187-4141-487c-a9da-f42ad7f9b408 MTHSPL
SPL_SET_ID aae73dac-d092-4163-8a37-f1a7459a4217 MTHSPL
SPL_SET_ID aefa8a81-43ee-40db-8d75-8eff70c65ca6 MTHSPL
SPL_SET_ID b28867d2-23b6-4f52-975a-7bc368c5b357 MTHSPL
SPL_SET_ID c0d32a2e-6d69-4d5c-913d-e225174de39e MTHSPL
SPL_SET_ID c7a56694-0314-4b2d-965e-c665e7453e5b MTHSPL
SPL_SET_ID c7fd585a-99b7-4309-b003-a6cbef05372c MTHSPL
SPL_SET_ID c95a55d2-68cc-4a55-a15c-c308ad8c43eb MTHSPL
SPL_SET_ID cd41844a-cc17-4691-aa71-842ba09f3276 MTHSPL
SPL_SET_ID cf2129df-14c6-45be-89b1-9d8b65d56395 MTHSPL
SPL_SET_ID d0c29c3a-4dc1-4c00-add9-3075318e74ca MTHSPL
SPL_SET_ID d16a48c5-6b71-40a0-bcda-204f043fe832 MTHSPL
SPL_SET_ID d707ecc1-198d-40cd-98c1-e43ff6f071e6 MTHSPL
SPL_SET_ID dbba90dd-e29c-41fc-b2e9-8c1af162586b MTHSPL
SPL_SET_ID f934b49f-5e20-4870-abec-177d28b8cb7a MTHSPL
SPL_SET_ID f9be4643-c5d1-4bd2-a1fe-7f5e69a9acad MTHSPL
SPL_SET_ID fafea500-1c69-4026-920c-5e558088ffd9 MTHSPL
SUBSET_MEMBER 900000000000497000~MAPTARGET~g15.. SNOMEDCT_US
SUBSET_MEMBER 900000000000497000~MAPTARGET~X80G9 SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
TERMUI T029950 MSH
TERMUI T029952 MSH
TH NLM (1963) MSH
TH UNK (19XX) MSH
TYPE_ID 900000000000003001 SNOMEDCT_US
TYPE_ID 900000000000013009 SNOMEDCT_US
UWT Anatomical Structure UWDA
VANDF_RECORD 50.416^636^Active/Master NDFRT
VANDF_RECORD 50.6^367^Active/Master NDFRT
VUID 4018039 NDFRT

Additional Concept Data:  (none)

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