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| Terms & Properties |
Concept Unique Identifier (CUI): C0030095
NCI Thesaurus Code: C2283 (see NCI Thesaurus info)
Semantic Type: Pharmacologic Substance
Semantic Type: Amino Acid, Peptide, or Protein
Semantic Type: Hormone
NCIt Definition: Oxytocin (9 aa, ~1 kDa) is encoded by the human OXT gene. This protein plays a role in smooth muscle contraction in both the mammary gland and uterus. Oxytocin also may also be involved in maternal-newborn bonding, cognition and many other psychological and physiological processes.
CSP Definition: peptide hormone produced by the posterior lobe of the pituitary gland that induces contraction of the smooth muscle of the uterus and the myoepithelial cells of the mammary gland.
MSH Definition: A nonapeptide hormone released from the neurohypophysis (PITUITARY GLAND, POSTERIOR). It differs from VASOPRESSIN by two amino acids at residues 3 and 8. Oxytocin acts on SMOOTH MUSCLE CELLS, such as causing UTERINE CONTRACTIONS and MILK EJECTION.
Synonyms & Abbreviations: (see Synonym Details)
| 1-({(4R,7S,10S,13S,16S,19R)-19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-16-(4-hydroxybenzyl)-13-[(1S)-1-methylpropyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl}carbonyl)-L-prolyl-L-leucylglycinamide |
| 3-Isoleucine-8-Leucine Vasopressin |
| CYIQNCPLG-NH2 |
| Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Leu-Gly-NH2, cyclic 1-6 disulfide |
| Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Leu-Gly-NH2 |
| Ocytocin |
| OXT |
| Oxytocin (substance) |
| Oxytocin [Chemical/Ingredient] |
| oxytocin |
| Product containing oxytocin (medicinal product) |
| Product containing oxytocin |
| Vasporessin, 3-Isoleucine-8-Leucine |
External Source Codes:
| NCI Thesaurus Code | C2283 (see NCI Thesaurus info) |
| CAS Registry Number | 50-56-6 (see NLM ChemIDplus info) |
| OMIM Number | 167050 (see OMIM info) |
| Swiss Prot | P01178 (see UniProt/Swiss-Prot info) |
Other Properties:
| Name | Value | Source |
|---|---|---|
| ACTIVE | 1 | SNOMEDCT_US |
| AQL | AA AD AE AG AI AN BI BL CF CH CL CS CT DE DF EC GE HI IM IP ME PD PH PK PO RE SD SE ST TO TU UR | MSH |
| AUTHORITY | Gray's 38th ed:1886 | FMA |
| CASE_SIGNIFICANCE_ID | 900000000000448009 | SNOMEDCT_US |
| CHARACTERISTIC_TYPE_ID | 900000000000011006 | SNOMEDCT_US |
| CHEBI_ID | CHEBI:7872 | NCI |
| Contributing_Source | CTRP | NCI |
| CTV3ID | g15.. | SNOMEDCT_US |
| CTV3ID | X80G9 | SNOMEDCT_US |
| DC | 1 | MSH |
| DEFINITION_STATUS_ID | 900000000000074008 | SNOMEDCT_US |
| DID | 2334-5056 | CSP |
| DX | 19600101 | MSH |
| EFFECTIVE_TIME | 20020131 | SNOMEDCT_US |
| FDA_UNII_CODE | 1JQS135EYN | DRUGBANK |
| FDA_UNII_CODE | 1JQS135EYN | NDFRT |
| FX | D018045 | MSH |
| HN | ALPHA-HYPOPHAMINE was see OXYTOCIN 1977-93; ISOLEUCYL, LEUCYL VASOPRESSIN; VASOPRESSIN, ISOLEUCYL-LEUCYL; VASOTOCIN, LEUCYL, & 3-ISOLEUCINE,8-LEUCINE VASOPRESSIN were see OXYTOCIN 1983-93 | MSH |
| LEVEL | Ingredient | NDFRT |
| MDA | 19990101 | MSH |
| MESH_DEFINITION | A nonapeptide hormone released from the neurohypophysis (PITUITARY GLAND, POSTERIOR). It differs from VASOPRESSIN by two amino acids at residues 3 and 8. Oxytocin acts on SMOOTH MUSCLE CELLS, such as causing UTERINE CONTRACTIONS and MILK EJECTION. | NDFRT |
| MESH_DUI | D010121 | NDFRT |
| MESH_NAME | Oxytocin | NDFRT |
| MESH_UI | M0015703 | NDFRT |
| MMR | 20080708 | MSH |
| MN | D06.472.699.631.692.433 | MSH |
| MN | D12.644.548.691.692.433 | MSH |
| MODIFIER_ID | 900000000000451002 | SNOMEDCT_US |
| NDFRT_KIND | DRUG_KIND | NDFRT |
| NDFRT_KIND | INGREDIENT_KIND | NDFRT |
| NUI | N0000006473 | NDFRT |
| NUI | N0000146381 | NDFRT |
| OL | use OXYTOCIN to search ALPHA-HYPOPHAMINE 1977-93 & ISOLEUCYL, LEUCYL VASOPRESSIN; VASOPRESSIN, ISOLEUCYL-LEUCYL; VASOTOCIN, LEUCYL, & 3-ISOLEUCINE,8-LEUCINE VASOPRESSIN 1983-93 | MSH |
| PA | D010120 | MSH |
| PM | ALPHA-HYPOPHAMINE was see OXYTOCIN 1977-93; ISOLEUCYL, LEUCYL VASOPRESSIN; VASOPRESSIN, ISOLEUCYL-LEUCYL; VASOTOCIN, LEUCYL, & 3-ISOLEUCINE,8-LEUCINE VASOPRESSIN were see OXYTOCIN 1983-93 | MSH |
| RN | 50-56-6 | MSH |
| RXAUI | 2072690 | RXNORM |
| RXAUI | 252889 | RXNORM |
| RXAUI | 2600181 | RXNORM |
| RXAUI | 2981274 | RXNORM |
| RXAUI | 3027614 | RXNORM |
| RXAUI | 3136921 | RXNORM |
| RXAUI | 3209543 | RXNORM |
| RXAUI | 3209544 | RXNORM |
| RXAUI | 3209835 | RXNORM |
| RXAUI | 3211586 | RXNORM |
| RXAUI | 3211590 | RXNORM |
| RXCUI | 7824 | RXNORM |
| SID | BIOD00016 | DRUGBANK |
| SID | BTD00016 | DRUGBANK |
| SPL_SET_ID | 03dc86d3-575f-4c65-b06d-2613efbcd943 | MTHSPL |
| SPL_SET_ID | 06aa4d89-e7a3-417b-bb5e-20ff7058f529 | MTHSPL |
| SPL_SET_ID | 10e46b39-7903-4390-b72d-865291245b4c | MTHSPL |
| SPL_SET_ID | 1F7D5370-94D6-4BE4-9FB5-990DC924C815 | MTHSPL |
| SPL_SET_ID | 29aa28ea-36ef-431c-af1d-4aeec4c0e82a | MTHSPL |
| SPL_SET_ID | 32ab2505-9bb7-49d6-af24-ec95c8edfa8b | MTHSPL |
| SPL_SET_ID | 447c07c9-5343-4370-b046-5725a7e45398 | MTHSPL |
| SPL_SET_ID | 48d3f634-c7f4-48d4-895a-9ef77456cf49 | MTHSPL |
| SPL_SET_ID | 4cdbf233-28db-4697-9787-85366ff19bc6 | MTHSPL |
| SPL_SET_ID | 6d4b2c25-2e5d-49b5-93bc-2ae8a20916d1 | MTHSPL |
| SPL_SET_ID | 6d7d1280-f286-4f39-89f3-2b96571810e6 | MTHSPL |
| SPL_SET_ID | 736b2590-79e8-4bd0-ab54-84ff7e29a030 | MTHSPL |
| SPL_SET_ID | 7554cc4d-8d27-453d-9dcc-6311fc4f1b27 | MTHSPL |
| SPL_SET_ID | 89156ba1-931f-4f3f-ab8a-b1b63e9e4c63 | MTHSPL |
| SPL_SET_ID | 8fbd0773-6645-4235-9ef2-56edf9c7fb83 | MTHSPL |
| SPL_SET_ID | 969d5b35-0add-4c23-9605-6a5b6ab65c95 | MTHSPL |
| SPL_SET_ID | 97113a71-c02e-41b7-950b-6d4ebe5e7156 | MTHSPL |
| SPL_SET_ID | 9e16a32c-94dd-4738-869f-847a58b3d996 | MTHSPL |
| SPL_SET_ID | a93b13fc-bebe-4669-befd-ab515416c203 | MTHSPL |
| SPL_SET_ID | a9b62187-4141-487c-a9da-f42ad7f9b408 | MTHSPL |
| SPL_SET_ID | aae73dac-d092-4163-8a37-f1a7459a4217 | MTHSPL |
| SPL_SET_ID | aefa8a81-43ee-40db-8d75-8eff70c65ca6 | MTHSPL |
| SPL_SET_ID | b28867d2-23b6-4f52-975a-7bc368c5b357 | MTHSPL |
| SPL_SET_ID | c0d32a2e-6d69-4d5c-913d-e225174de39e | MTHSPL |
| SPL_SET_ID | c7a56694-0314-4b2d-965e-c665e7453e5b | MTHSPL |
| SPL_SET_ID | c7fd585a-99b7-4309-b003-a6cbef05372c | MTHSPL |
| SPL_SET_ID | c95a55d2-68cc-4a55-a15c-c308ad8c43eb | MTHSPL |
| SPL_SET_ID | cd41844a-cc17-4691-aa71-842ba09f3276 | MTHSPL |
| SPL_SET_ID | cf2129df-14c6-45be-89b1-9d8b65d56395 | MTHSPL |
| SPL_SET_ID | d0c29c3a-4dc1-4c00-add9-3075318e74ca | MTHSPL |
| SPL_SET_ID | d16a48c5-6b71-40a0-bcda-204f043fe832 | MTHSPL |
| SPL_SET_ID | d707ecc1-198d-40cd-98c1-e43ff6f071e6 | MTHSPL |
| SPL_SET_ID | dbba90dd-e29c-41fc-b2e9-8c1af162586b | MTHSPL |
| SPL_SET_ID | f934b49f-5e20-4870-abec-177d28b8cb7a | MTHSPL |
| SPL_SET_ID | f9be4643-c5d1-4bd2-a1fe-7f5e69a9acad | MTHSPL |
| SPL_SET_ID | fafea500-1c69-4026-920c-5e558088ffd9 | MTHSPL |
| SUBSET_MEMBER | 900000000000497000~MAPTARGET~g15.. | SNOMEDCT_US |
| SUBSET_MEMBER | 900000000000497000~MAPTARGET~X80G9 | SNOMEDCT_US |
| SUBSET_MEMBER | 900000000000508004~ACCEPTABILITYID~900000000000548007 | SNOMEDCT_US |
| SUBSET_MEMBER | 900000000000508004~ACCEPTABILITYID~900000000000549004 | SNOMEDCT_US |
| SUBSET_MEMBER | 900000000000509007~ACCEPTABILITYID~900000000000548007 | SNOMEDCT_US |
| SUBSET_MEMBER | 900000000000509007~ACCEPTABILITYID~900000000000549004 | SNOMEDCT_US |
| TERMUI | T029950 | MSH |
| TERMUI | T029952 | MSH |
| TH | NLM (1963) | MSH |
| TH | UNK (19XX) | MSH |
| TYPE_ID | 900000000000003001 | SNOMEDCT_US |
| TYPE_ID | 900000000000013009 | SNOMEDCT_US |
| UWT | Anatomical Structure | UWDA |
| VANDF_RECORD | 50.416^636^Active/Master | NDFRT |
| VANDF_RECORD | 50.6^367^Active/Master | NDFRT |
| VUID | 4018039 | NDFRT |
Additional Concept Data: (none)
URL to Bookmark: https://ncim-stage.nci.nih.gov/ncimbrowser/ConceptReport.jsp?dictionary=NCI Metathesaurus&code=C0030095
