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Nitrous Oxide (CUI C0028215) Suggest changes to this concept
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Terms & Properties

Concept Unique Identifier (CUI): C0028215

NCI Thesaurus Code: C73617  (see NCI Thesaurus info)

Semantic Type: Inorganic Chemical

Semantic Type: Pharmacologic Substance

Semantic Type: Biologically Active Substance

NCIt Definition: A naturally occurring gas that is colorless and non flammable. It can be manufactured and used for a variety of things such as a pharmacologic agent to produce anesthesia, a food additive as a propellant, and an additive to fuels to increase available oxygen in combustion.

CSP Definition: "laughing gas"; N2O.

MSH Definition: Nitrogen oxide (N2O). A colorless, odorless gas that is used as an anesthetic and analgesic. High concentrations cause a narcotic effect and may replace oxygen, causing death by asphyxia. It is also used as a food aerosol in the preparation of whipping cream.

Synonyms & Abbreviations: (see Synonym Details)
Dinitrogen Monoxide
Gas, Laughing
Laughing Gas
N2O - Nitrous oxide
Nitrious oxide
Nitrogen oxide (N2O)
Nitrogen Protoxide
Nitrous oxide (product)
Nitrous oxide (substance)
Nitrous Oxide [Chemical/Ingredient]
Nitrous oxide gas
nitrous oxide
Oxide, Nitrous

External Source Codes: 
NCI Thesaurus Code C73617 (see NCI Thesaurus info)
CAS Registry Number 10024-97-2 (see NLM ChemIDplus info)
FDA UNII Code K50XQU1029

Other Properties: Property Definitions
Name Value Source
ACTIVE 1 SNOMEDCT_US
AQL AD AE AG AI AN BL CF CH CL CS CT EC HI IM IP ME PD PK PO RE SD ST TO TU UR MSH
CASE_SIGNIFICANCE_ID 900000000000020002 SNOMEDCT_US
CASE_SIGNIFICANCE_ID 900000000000448009 SNOMEDCT_US
CHARACTERISTIC_TYPE_ID 900000000000011006 SNOMEDCT_US
CHEBI_ID CHEBI:17045 NCI
Chemical_Formula N2O NCI
Contributing_Source FDA NCI
CTV3ID o26.. SNOMEDCT_US
CTV3ID XUX8T SNOMEDCT_US
DC 1 MSH
DEFINITION_STATUS_ID 900000000000074008 SNOMEDCT_US
DID 2083-5252 CSP
DX 19630101 MSH
EFFECTIVE_TIME 20020131 SNOMEDCT_US
EFFECTIVE_TIME 20030131 SNOMEDCT_US
FDA_UNII_CODE K50XQU1029 DRUGBANK
FDA_UNII_CODE K50XQU1029 NDFRT
HN 1963; for NITROGEN PROTOXIDE use NITRIC OXIDE 1982-2008 MSH
LEVEL Ingredient NDFRT
MDA 19990101 MSH
MESH_DEFINITION Nitrogen oxide (N2O). A colorless, odorless gas that is used as an anesthetic and analgesic. High concentrations cause a narcotic effect and may replace oxygen, causing death by asphyxia. It is also used as a food aerosol in the preparation of whipping cream. NDFRT
MESH_DUI D009609 NDFRT
MESH_NAME Nitrous Oxide NDFRT
MESH_UI M0014927 NDFRT
MMR 20130708 MSH
MN D01.362.635.625 MSH
MN D01.625.550.550 MSH
MN D01.650.550.587.650 MSH
MODIFIER_ID 900000000000451002 SNOMEDCT_US
NDFRT_KIND DRUG_KIND NDFRT
NDFRT_KIND INGREDIENT_KIND NDFRT
NUI N0000007349 NDFRT
NUI N0000147387 NDFRT
PA D018685 MSH
PA D018712 MSH
PM 1963; for NITROGEN PROTOXIDE see NITRIC OXIDE 1982-2008 MSH
RN K50XQU1029 MSH
RR 10024-97-2 (Nitrous Oxide) MSH
RXAUI 2072562 RXNORM
RXAUI 242717 RXNORM
RXAUI 3188349 RXNORM
RXAUI 3203531 RXNORM
RXAUI 3203532 RXNORM
RXAUI 3207141 RXNORM
RXAUI 3207149 RXNORM
RXAUI 3207204 RXNORM
RXAUI 3207205 RXNORM
RXAUI 3279427 RXNORM
RXAUI 3279498 RXNORM
RXCUI 7486 RXNORM
SOS A short-acting gaseous anesthetic that is sometimes used as an aerosol propellant and is inhaled for its intoxicating effects. A depressant without depressant effects on the spinal cord. When used therapeutically, the effects are those of anesthesia and analgesia. In recreational use, when it is in pure form for less than a minute, its effects are closer to those of the vaporous anesthetics ether and chloroform than other depressants, making the user giddy or exhilarated for about 5 minutes. Occasionally hallucinations occur. Excessive doses may cause nausea, vomiting, or unconsciousness, often because of lack of oxygen. Discovered in the 1770s by Joseph Priestley, but not used as an anesthetic until the middle of the 19th century, it was the first really effective modern anesthetic, followed by ether and chloroform. Also called laughing gas or nitrogen monoxide. AOD
SOS Classification: volatile inhalants. AOD
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SPL_SET_ID eebd56c1-4ab3-409b-9767-e54dc42f2fce MTHSPL
SPL_SET_ID f35d5f55-3b83-4ce9-bd3a-2625c00a9282 MTHSPL
SPL_SET_ID f39618a6-a387-44fe-b5f9-bbfedc95904b MTHSPL
SPL_SET_ID f5f0f2f7-86a2-41f0-a6cd-3b8cb916dedd MTHSPL
SPL_SET_ID fa835c4c-a45c-4443-a6e5-995bfcccd587 MTHSPL
SPL_SET_ID ff856132-0ba3-42aa-bb48-dc1f7efd9a94 MTHSPL
SPL_SET_ID ffcfc7c1-5806-4f37-9a0f-f64cb06410e0 MTHSPL
SUBSET_MEMBER 900000000000497000~MAPTARGET~o26.. SNOMEDCT_US
SUBSET_MEMBER 900000000000497000~MAPTARGET~XUX8T SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
TERMUI T028509 MSH
TERMUI T028598 MSH
TERMUI T028599 MSH
TH FDA SRS (2014) MSH
TH NLM (1994) MSH
TH UNK (19XX) MSH
TH USP (19XX) MSH
TYPE_ID 900000000000003001 SNOMEDCT_US
TYPE_ID 900000000000013009 SNOMEDCT_US
VANDF_RECORD 50.416^1746^Active/Master NDFRT
VANDF_RECORD 50.6^1706^Active/Master NDFRT
VUID 4019137 NDFRT

Additional Concept Data:  (none)

URL to Bookmark: https://ncim-stage.nci.nih.gov/ncimbrowser/ConceptReport.jsp?dictionary=NCI Metathesaurus&code=C0028215

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