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Neutropenia (CUI C0027947) Suggest changes to this concept
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Terms & Properties

Concept Unique Identifier (CUI): C0027947

NCI Thesaurus Code: C80520  (see NCI Thesaurus info)

Semantic Type: Finding

NCIt Definition: A decrease in the number of neutrophils in the peripheral blood.

HPO Definition: An abnormally low number of neutrophils in the peripheral blood. [HPO:probinson]

NCI-GLOSS Definition: A condition in which there is a lower-than-normal number of neutrophils (a type of white blood cell).

CTCAE Definition: A finding based on laboratory test results that indicate a decrease in number of neutrophils in a blood specimen.

NICHD Definition: Abnormally low level of neutrophils in the blood.

CSP Definition: decrease in the number of neutrophilic leukocytes in the blood.

MSH Definition: A decrease in the number of NEUTROPHILS found in the blood.

Synonyms & Abbreviations: (see Synonym Details)
Granulocytopenia
Low blood neutrophil count
Neutropenia (finding)
Neutropenia [Disease/Finding]
Neutropenia NOS
Neutropenia, unspecified
Neutropenias
Neutropenia
Neutropenic disorder (disorder)
Neutropenic disorder
Neutrophil count below reference range
Neutrophil count decreased
Neutrophil count low
NEUTROPHILS DECREASED
Neutrophils reduced
Peripheral neutropenia

External Source Codes: 
NCI Thesaurus Code C80520 (see NCI Thesaurus info)

Other Properties: Property Definitions
Name Value Source
ACTIVE 1 SNOMEDCT_US
AQL BL CF CI CL CN CO DG DH DI DT EC EH EM EN EP ET GE HI IM ME MI MO NU PA PC PP PS PX RH RT SU TH UR VE VI MSH
CASE_SIGNIFICANCE_ID 900000000000448009 SNOMEDCT_US
CHARACTERISTIC_TYPE_ID 900000000000011006 SNOMEDCT_US
Contributing_Source CTRP NCI
Contributing_Source MedDRA NCI
Contributing_Source NICHD NCI
CTV3ID 42J2. SNOMEDCT_US
CTV3ID Xa9E8 SNOMEDCT_US
DC 1 MSH
DEFINITION_STATUS_ID 900000000000073002 SNOMEDCT_US
DEFINITION_STATUS_ID 900000000000074008 SNOMEDCT_US
DID 5000-0035 CSP
DX 19910101 MSH
EFFECTIVE_TIME 20020131 SNOMEDCT_US
EFFECTIVE_TIME 20180131 SNOMEDCT_US
EXCLUDES1 neutropenic splenomegaly (D73.81) ICD10CM
EXCLUDES1 transient neonatal neutropenia (P61.5) ICD10CM
HN 91(75); was see under AGRANULOCYTOSIS 1975-90 MSH
HPO_COMMENT Mild neutropenia is defined as an absolute neutrophil cont between 1000 and 1500 cells per microliter, moderte as between 500 and 100, and severe as less than 500 cells. HPO
ICA Use additional code for any associated: fever (780.61); mucositis (478.11, 528.00-528.09, 538, 616.81) ICD9CM
MDA 19990101 MSH
MESH_DEFINITION A decrease in the number of NEUTROPHILS found in the blood. NDFRT
MESH_DUI D009503 NDFRT
MESH_NAME Neutropenia NDFRT
MESH_UI M0014782 NDFRT
MMR 20110624 MSH
MN C15.378.553.546.184.564 MSH
MODIFIER_ID 900000000000451002 SNOMEDCT_US
NCI_THESAURUS_CODE C80520 PDQ
NDFRT_KIND DISEASE_KIND NDFRT
NICHD_Hierarchy_Term Neutropenia NCI
NUI N0000002182 NDFRT
OL search AGRANULOCYTOSIS 1966-74 MSH
ORDER_NO 03487 ICD10CM
ORDER_NO 03494 ICD10CM
ORIG_STY Secondary related condition PDQ
PID 4458 PDQ
PM 91; was see under AGRANULOCYTOSIS 1975-90 MSH
PRIMARY_PATH 10029354$10029355$10047954$10005329$Neutropenia$Neutropenias$White blood cell disorders$Blood and lymphatic system disorders MDR
PRIMARY_PATH 10029366$10047938$10018851$10022891$Neutrophil count decreased$White blood cell analyses$Haematology investigations (incl blood groups)$Investigations MDR
PRIMARY_SOC 10005329 MDR
PRIMARY_SOC 10022891 MDR
PT_IN_VERSION 10.0 MDR
PT_IN_VERSION 10.1 MDR
PT_IN_VERSION 11.0 MDR
PT_IN_VERSION 11.1 MDR
PT_IN_VERSION 12.0 MDR
PT_IN_VERSION 12.1 MDR
PT_IN_VERSION 13.0 MDR
PT_IN_VERSION 13.1 MDR
PT_IN_VERSION 14.0 MDR
PT_IN_VERSION 14.1 MDR
PT_IN_VERSION 15.0 MDR
PT_IN_VERSION 15.1 MDR
PT_IN_VERSION 16.0 MDR
PT_IN_VERSION 16.1 MDR
PT_IN_VERSION 17.0 MDR
PT_IN_VERSION 17.1 MDR
PT_IN_VERSION 18.0 MDR
PT_IN_VERSION 18.1 MDR
PT_IN_VERSION 19.0 MDR
PT_IN_VERSION 19.1 MDR
PT_IN_VERSION 20.0 MDR
PT_IN_VERSION 20.1 MDR
PT_IN_VERSION 8.0 MDR
PT_IN_VERSION 8.1 MDR
PT_IN_VERSION 9.0 MDR
PT_IN_VERSION 9.1 MDR
REF orcid.org/0000-0001-5208-3432 HPO
RXAUI 3206764 RXNORM
RXAUI 3206765 RXNORM
RXCUI 1023774 RXNORM
SID HP:0005515 HPO
SID HP:0005533 HPO
SMQ_TERM_ADDVERSION 19.0 MDR
SMQ_TERM_ADDVERSION 8.1 MDR
SMQ_TERM_CAT A MDR
SMQ_TERM_CAT E MDR
SMQ_TERM_LEVEL 4 MDR
SMQ_TERM_LEVEL 5 MDR
SMQ_TERM_LMVERSION 19.0 MDR
SMQ_TERM_LMVERSION 8.1 MDR
SMQ_TERM_SCOPE 1 MDR
SMQ_TERM_SCOPE 2 MDR
SMQ_TERM_STATUS A MDR
SMQ_TERM_WEIGHT 0 MDR
SNOMED_CID 303011007 NDFRT
SOS Excludes: neutropenic splenomegaly (289.53); transitory neonatal neutropenia (776.7) ICD9CM
SUBSET_MEMBER 447562003~CORRELATIONID~447561005 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPADVICE~ALWAYS D70 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPCATEGORYID~447637006 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPGROUP~1 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPPRIORITY~1 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPRULE~TRUE SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPTARGET~D70 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~CORRELATIONID~447561005 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~ALWAYS D70.9 | CONSIDER ADDITIONAL CODE TO IDENTIFY SPECIFIC CONDITION OR DISEASE | DESCENDANTS NOT EXHAUSTIVELY MAPPED SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~ALWAYS D70.9 | CONSIDER ADDITIONAL CODE TO IDENTIFY SPECIFIC CONDITION OR DISEASE SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~IF AGE AT ONSET OF CLINICAL FINDING BEFORE 29.0 DAYS CHOOSE P61.5 | MAP OF SOURCE CONCEPT IS CONTEXT DEPENDENT SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~IF CONSTITUTIONAL NEUTROPENIA CHOOSE D70.8 | CONSIDER ADDITIONAL CODE TO IDENTIFY SPECIFIC CONDITION OR DISEASE | MAP OF SOURCE CONCEPT IS CONTEXT DEPENDENT SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~IF TRANSIENT NEONATAL NEUTROPENIA CO-OCCURRENT AND DUE TO NEONATAL BACTERIAL SEPSIS CHOOSE P36.9 | CONSIDER ADDITIONAL CODE TO IDENTIFY SPECIFIC CONDITION OR DISEASE | MAP OF SOURCE CONCEPT IS CONTEXT DEPENDENT SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~IF TRANSIENT NEONATAL NEUTROPENIA CO-OCCURRENT AND DUE TO NEONATAL BACTERIAL SEPSIS CHOOSE P61.5 | MAP OF SOURCE CONCEPT IS CONTEXT DEPENDENT SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~IF TRANSIENT NEONATAL NEUTROPENIA DUE TO CONGENITAL VIRAL INFECTION CHOOSE P35.9 | MAP OF SOURCE CONCEPT IS CONTEXT DEPENDENT SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~IF TRANSIENT NEONATAL NEUTROPENIA DUE TO CONGENITAL VIRAL INFECTION CHOOSE P61.5 | MAP OF SOURCE CONCEPT IS CONTEXT DEPENDENT SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~MAP SOURCE CONCEPT CANNOT BE CLASSIFIED WITH AVAILABLE DATA SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPCATEGORYID~447637006 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPCATEGORYID~447638001 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPCATEGORYID~447639009 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPGROUP~1 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPGROUP~2 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~1 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~2 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~3 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~4 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~5 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~IFA 445518008 | Age at onset of clinical finding (observable entity) | < 29.0 days SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~IFA 722925004 | Transient neonatal neutropenia due to congenital viral infection | SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~IFA 722926003 | Transient neonatal neutropenia co-occurrent and due to neonatal bacterial sepsis | SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~IFA 735431006 | Constitutional neutropenia | SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~OTHERWISE TRUE SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~TRUE SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~D70.8 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~D70.9 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~P35.9 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~P36.9 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~P61.5 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~ SNOMEDCT_US
SUBSET_MEMBER 900000000000497000~MAPTARGET~42J2. SNOMEDCT_US
SUBSET_MEMBER 900000000000497000~MAPTARGET~Xa9E8 SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
TERMUI T028320 MSH
TH NLM (1975) MSH
TYPE_ID 900000000000003001 SNOMEDCT_US
TYPE_ID 900000000000013009 SNOMEDCT_US
USE_ADDITIONAL code for any associated: ICD10CM
USE_ADDITIONAL fever (R50.81) ICD10CM
USE_ADDITIONAL mucositis (J34.81, K12.3-, K92.81, N76.81) ICD10CM

Additional Concept Data:  (none)

URL to Bookmark: https://ncim-stage.nci.nih.gov/ncimbrowser/ConceptReport.jsp?dictionary=NCI Metathesaurus&code=C0027947

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