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Neuroglia (CUI C0027836) Suggest changes to this concept
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Terms & Properties

Concept Unique Identifier (CUI): C0027836

NCI Thesaurus Code: C12615  (see NCI Thesaurus info)

Semantic Type: Cell

NCIt Definition: A non-neuronal cell of the nervous system. Glial cells have diverse roles, including in regulation of neuronal survival and differentiation, maintenance of ion and neurotransmitter concentrations in the neuronal environment, synapse formation, and support of synaptic interactions and electrical signal propagation.

NCI-GLOSS Definition: Any of the cells that hold nerve cells in place and help them work the way they should. The types of neuroglia include oligodendrocytes, astrocytes, microglia, and ependymal cells.

CSP Definition: non-neuronal cells of the nervous system; they provide physical support, respond to injury, regulate the ionic and chemical composition of the extracellular milieu, form the myelin insulation of nervous pathways, guide neuronal migration during development, and exchange metabolites with neurons.

MSH Definition: The non-neuronal cells of the nervous system. They not only provide physical support, but also respond to injury, regulate the ionic and chemical composition of the extracellular milieu, participate in the BLOOD-BRAIN BARRIER and BLOOD-RETINAL BARRIER, form the myelin insulation of nervous pathways, guide neuronal migration during development, and exchange metabolites with neurons. Neuroglia have high-affinity transmitter uptake systems, voltage-dependent and transmitter-gated ion channels, and can release transmitters, but their role in signaling (as in many other functions) is unclear.

Synonyms & Abbreviations: (see Synonym Details)
Cell, Glial
Cell, Neuroglial
Cells, Glial
Cells, Neuroglial
Glia (body structure)
Glial cell (cell)
Glial Cells
glial cell
glia
Kolliker Reticulum
Kolliker's reticulum
nerve cement
Neuroglial cells set
Neuroglial Cells
Neuroglial cell
neuroglia
Non-neuronal cell
Set of glial cells
Set of neuroglial cells

External Source Codes: 
NCI Thesaurus Code C12615 (see NCI Thesaurus info)

Other Properties: Property Definitions
Name Value Source
ACTIVE 1 SNOMEDCT_US
AQL CH CL CY DE EN IM ME MI PA PH PS RE SE TR UL VI MSH
AUTHORITY Bloom & Fawcett 1975 FMA
AUTHORITY Bloom & Fawcett 94: 355 FMA
AUTHORITY Burt 93:31 FMA
AUTHORITY Gray's 99: 937 FMA
AUTHORITY Gray's 99:937,948 FMA
AUTHORITY Gray's 99:937 FMA
AUTHORITY Rosse MD FMA
AUTHORITY Rosse FMA
AUTHORITY Terminologia Anatomica 1998 FMA
CASE_SIGNIFICANCE_ID 900000000000448009 SNOMEDCT_US
CHARACTERISTIC_TYPE_ID 900000000000227009 SNOMEDCT_US
CTV3ID XU9c8 SNOMEDCT_US
CTV3ID XUH4e SNOMEDCT_US
DATE_LAST_MODIFIED Fri Jun 09 10:51:56 PDT 2000 FMA
DATE_LAST_MODIFIED Fri Jun 09 11:04:21 PDT 2000 FMA
DATE_LAST_MODIFIED Fri Jun 09 11:32:48 PDT 2000 FMA
DATE_LAST_MODIFIED Fri Jun 09 15:56:38 PDT 2000 FMA
DATE_LAST_MODIFIED Fri Jun 09 15:57:10 PDT 2000 FMA
DC 1 MSH
DEFINITION_STATUS_ID 900000000000074008 SNOMEDCT_US
DID 2047-3472 CSP
DX 19660101 MSH
EFFECTIVE_TIME 20020131 SNOMEDCT_US
ICD-O-3_CODE C47.9 SNOMEDCT_US
LANGUAGE Latin FMA
MDA 19990101 MSH
MMR 20141121 MSH
MN A08.637 MSH
MN A11.650 MSH
MODIFIER_ID 900000000000451002 SNOMEDCT_US
SOS Collectively, the non-neuronal cellular components of the central nervous system that, together with the fine tissue web that they generate, make up the structural and functional support system of the brain and spinal cord. Neuroglial cells are usually divided into two major categories, macroglia and microglia. The macroglia consists of astrocytes and oligodendrocytes (oligodendroglia), which are of ectodermal origin. Astrocytes may be of protoplasmic or fibrillary type, the latter developing particularly in later life or in response to neural tissue injury. Oligodendrocytes frequently surround neurons closely as satellite cells or lie among the myelinated axon bundles as interfascicular oligodendroglia. All of these types may be involved in the control of the ionic and molecular medium and in the synthesis of important neurally active materials. Interfascicular oligoglia are also concerned with the formation and maintenance of myelin. The microglia, of mesodermal origin, are believed to be derived from blood vessels, and they form wandering phagocytes. AOD
SUBSET_MEMBER 446608001~MAPTARGET~C47.9 SNOMEDCT_US
SUBSET_MEMBER 734138000~TARGETCOMPONENT~727123002 SNOMEDCT_US
SUBSET_MEMBER 900000000000497000~MAPTARGET~XU9c8 SNOMEDCT_US
SUBSET_MEMBER 900000000000497000~MAPTARGET~XUH4e SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
TA_ID A14.0.00.005 FMA
TERMUI T028181 MSH
TERMUI T028182 MSH
TERMUI T028183 MSH
TERMUI T437487 MSH
TH NLM (1966) MSH
TH NLM (1994) MSH
TH NLM (2002) MSH
TRANSLATION French: Neuroglie FMA
TYPE_ID 900000000000003001 SNOMEDCT_US
TYPE_ID 900000000000013009 SNOMEDCT_US
UWT Anatomical Structure UWDA

Additional Concept Data:  (none)

URL to Bookmark: https://ncim-stage.nci.nih.gov/ncimbrowser/ConceptReport.jsp?dictionary=NCI Metathesaurus&code=C0027836

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