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Myositis (CUI C0027121) Suggest changes to this concept
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Terms & Properties

Concept Unique Identifier (CUI): C0027121

NCI Thesaurus Code: C27578  (see NCI Thesaurus info)

Semantic Type: Disease or Syndrome

NCIt Definition: An inflammatory process affecting the skeletal muscles. Causes include infections, injuries, and autoimmune disorders.

RADLEX Definition: Inflammation of skeletal muscle (muscle, skeletal). Infectious, autoimmune, and paraneoplastic processes represent some of the more common conditions that may be associated with myositis. (From Adams et al., Principles of Neurology, 6th ed., pp 1402-13) [MeSH]

HPO Definition: A general term for inflammation of the muscles without respect to the underlying cause. [HPO:sdoelken]

MEDLINEPLUS Definition: 

Myositis means inflammation of the muscles that you use to move your body. An injury, infection, or autoimmune disease can cause it. Two specific kinds are polymyositis and dermatomyositis. Polymyositis causes muscle weakness, usually in the muscles closest to the trunk of your body. Dermatomyositis causes muscle weakness, plus a skin rash.

Other symptoms of myositis may include

  • Fatigue after walking or standing
  • Tripping or falling
  • Trouble swallowing or breathing

Doctors may use a physical exam, lab tests, imaging tests and a muscle biopsy to diagnose myositis. There is no cure for these diseases, but you can treat the symptoms. Polymyositis and dermatomyositis are first treated with high doses of a corticosteroid. Other options include medications, physical therapy, exercise, heat therapy, assistive devices, and rest.

NIH: National Institute of Neurological Disorders and Stroke

CTCAE Definition: A disorder characterized by inflammation involving the skeletal muscles.

NICHD Definition: Inflammation affecting the skeletal muscles.

SNOMEDCT_US Definition: Inflammation of skeletal muscle, not including inflammation of cardiac muscle

CSP Definition: inflammation of skeletal muscle.

MSH Definition: Inflammation of a muscle or muscle tissue.

Synonyms & Abbreviations: (see Synonym Details)
INFLAMM MUSCLE DIS
INFLAMM MYOPATHY
Inflammatory disorder of muscle (disorder)
Inflammatory disorder of muscle
Inflammatory Muscle Diseases
Inflammatory Muscle Disease
Inflammatory Myopathies
Inflammatory myopathy NOS
Inflammatory myopathy
MUSCLE DIS INFLAMM
Muscle Disease, Inflammatory
Muscle Diseases, Inflammatory
Muscle inflammation
Myopathies, Inflammatory
MYOPATHY INFLAMM
Myopathy, Inflammatory
Myositides
Myositis (disorder)
Myositis [Disease/Finding]
Myositis, unspecified
myositis

External Source Codes: 
NCI Thesaurus Code C27578 (see NCI Thesaurus info)

Other Properties: Property Definitions
Name Value Source
ACTIVE 1 SNOMEDCT_US
AN note many specific myositis terms are available MSH
AQL BL CF CI CL CN CO DG DH DI DT EC EH EM EN EP ET GE HI IM ME MI MO NU PA PC PP PS PX RH RT SU TH UR VE VI MSH
CASE_SIGNIFICANCE_ID 900000000000448009 SNOMEDCT_US
CHARACTERISTIC_TYPE_ID 900000000000011006 SNOMEDCT_US
Contributing_Source MedDRA NCI
Contributing_Source NICHD NCI
CTV3ID X709d SNOMEDCT_US
CTV3ID XU7Bd SNOMEDCT_US
DATE_CREATED 04/23/2002 MEDLINEPLUS
DATE_CREATED 2010-12-28T11:14:59Z HPO
DATE_CREATED 2013-01-09T00:04:00 GARD
DATE_LAST_MODIFIED 2013-01-09T00:04:00 GARD
DC 1 MSH
DEFINITION_STATUS_ID 900000000000073002 SNOMEDCT_US
DID 1982-9705 CSP
DISEASE_IDENTIFIER_ID 13076 GARD
DISEASE_IDENTIFIER_ID 19485 GARD
DX 19600101 MSH
EFFECTIVE_TIME 20020131 SNOMEDCT_US
EFFECTIVE_TIME 20040731 SNOMEDCT_US
EXCLUDES2 inclusion body myositis [IBM] (G72.41) ICD10CM
HN MYOSITIS, EOSINOPHILIC was heading 1970-1980 MSH
HPO_COMMENT Many such conditions are considered likely to be caused by autoimmune conditions, rather than directly due to infection, although autoimmune conditions can be activated or exacerbated by infections. It is also a documented side effect of the lipid-lowering drugs such as statins and fibrates. Elevation of creatine kinase in blood is indicative of myositis. HPO
IAN DEFAULT ICD10
IDENTIFIER_TYPE_ID 1 GARD
IS_ACTIVE true GARD
MDA 19990101 MSH
MESH_DEFINITION Inflammation of a muscle or muscle tissue. NDFRT
MESH_DUI D009220 NDFRT
MESH_NAME Myositis NDFRT
MESH_UI M0014368 NDFRT
MIMTYPE 5 OMIM
MIMTYPEMEANING Mendelian phenotype or locus, molecular basis unknown. OMIM
MIMTYPEVALUE perc OMIM
MMR 20130708 MSH
MN C05.651.594 MSH
MN C10.668.491.562 MSH
MODIFIER_ID 900000000000451002 SNOMEDCT_US
MP_HEALTH_TOPIC_URL https://www.nlm.nih.gov/medlineplus/myositis.html MEDLINEPLUS
MP_OTHER_LANGUAGE_URL Spanish https://www.nlm.nih.gov/medlineplus/spanish/myositis.html MEDLINEPLUS
MP_PRIMARY_INSTITUTE_URL National Institute of Arthritis and Musculoskeletal and Skin Diseases http://www.niams.nih.gov/ MEDLINEPLUS
NDFRT_KIND DISEASE_KIND NDFRT
NICHD_Hierarchy_Term Myositis NCI
NUI N0000002094 NDFRT
ORDER_NO 18647 ICD10CM
ORDER_NO 18791 ICD10CM
PM MYOSITIS, EOSINOPHILIC was heading 1970-1980 MSH
PRIMARY_PATH 10028653$10021992$10028302$10028395$Myositis$Muscle infections and inflammations$Muscle disorders$Musculoskeletal and connective tissue disorders MDR
PRIMARY_SOC 10028395 MDR
PT_IN_VERSION 10.0 MDR
PT_IN_VERSION 10.1 MDR
PT_IN_VERSION 11.0 MDR
PT_IN_VERSION 11.1 MDR
PT_IN_VERSION 12.0 MDR
PT_IN_VERSION 12.1 MDR
PT_IN_VERSION 13.0 MDR
PT_IN_VERSION 13.1 MDR
PT_IN_VERSION 14.0 MDR
PT_IN_VERSION 14.1 MDR
PT_IN_VERSION 15.0 MDR
PT_IN_VERSION 15.1 MDR
PT_IN_VERSION 16.0 MDR
PT_IN_VERSION 16.1 MDR
PT_IN_VERSION 17.0 MDR
PT_IN_VERSION 17.1 MDR
PT_IN_VERSION 18.0 MDR
PT_IN_VERSION 18.1 MDR
PT_IN_VERSION 19.0 MDR
PT_IN_VERSION 19.1 MDR
PT_IN_VERSION 20.0 MDR
PT_IN_VERSION 20.1 MDR
PT_IN_VERSION 8.0 MDR
PT_IN_VERSION 8.1 MDR
PT_IN_VERSION 9.0 MDR
PT_IN_VERSION 9.1 MDR
REF orcid.org/0000-0001-5208-3432 HPO
RXAUI 3181058 RXNORM
RXAUI 3181063 RXNORM
RXAUI 3200257 RXNORM
RXAUI 3200973 RXNORM
RXAUI 3201068 RXNORM
RXAUI 3201071 RXNORM
RXCUI 1023065 RXNORM
SMQ_TERM_ADDVERSION 19.0 MDR
SMQ_TERM_ADDVERSION 8.1 MDR
SMQ_TERM_CAT A MDR
SMQ_TERM_CAT B MDR
SMQ_TERM_LEVEL 4 MDR
SMQ_TERM_LEVEL 5 MDR
SMQ_TERM_LMVERSION 19.0 MDR
SMQ_TERM_LMVERSION 8.1 MDR
SMQ_TERM_SCOPE 1 MDR
SMQ_TERM_STATUS A MDR
SMQ_TERM_WEIGHT 0 MDR
SNOMED_CID 128496001 NDFRT
SNOMED_CID 203110007 NDFRT
SNOMED_CID 26889001 NDFRT
SUBSET_MEMBER 447562003~CORRELATIONID~447561005 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPADVICE~ALWAYS M60.99 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPCATEGORYID~447637006 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPGROUP~1 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPPRIORITY~1 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPRULE~TRUE SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPTARGET~M60.99 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~CORRELATIONID~447561005 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~ALWAYS G72.49 | DESCENDANTS NOT EXHAUSTIVELY MAPPED SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~ALWAYS M60.9 | DESCENDANTS NOT EXHAUSTIVELY MAPPED SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPCATEGORYID~447637006 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPGROUP~1 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~1 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~TRUE SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~G72.49 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~M60.9 SNOMEDCT_US
SUBSET_MEMBER 900000000000497000~MAPTARGET~X709d SNOMEDCT_US
SUBSET_MEMBER 900000000000497000~MAPTARGET~XU7Bd SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
TERMUI T027490 MSH
TERMUI T369265 MSH
TERMUI T369266 MSH
TERMUI T369267 MSH
TERMUI T369268 MSH
TH NLM (1966) MSH
TH NLM (2000) MSH
TH OMIM (2013) MSH
TH ORD (2010) MSH
TYPE_ID 900000000000003001 SNOMEDCT_US
TYPE_ID 900000000000013009 SNOMEDCT_US

Additional Concept Data:  (none)

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