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Muscle Contraction (CUI C0026820) Suggest changes to this concept
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Terms & Properties

Concept Unique Identifier (CUI): C0026820

NCI Thesaurus Code: C30085  (see NCI Thesaurus info)

Semantic Type: Organ or Tissue Function

NCIt Definition: The process where thick (myosin) and thin (actin) filaments slide against each other to produce a shortening or tensing of the muscle cell or fiber.

GO Definition: A process in which force is generated within skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. In the skeletal muscle, the muscle contraction takes advantage of an ordered sarcomeric structure and in most cases it is under voluntary control. [GOC:mtg_cardio, GOC:mtg_muscle]

GO Definition: A process in which force is generated within muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. [GOC:ef, GOC:mtg_muscle, ISBN:0198506732]

GO Definition: OBSOLETE (was not defined before being made obsolete). [GOC:mah]

NICHD Definition: The process where thick (myosin) and thin (actin) filaments slide against each other to produce a shortening or tensing of the muscle cell or fiber.

CSP Definition: process leading to shortening and/or development of tension in muscle tissue; occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.

MSH Definition: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.

Synonyms & Abbreviations: (see Synonym Details)
Contractile
Contraction, Muscle
Contraction, Muscular
Contractions, Muscle
Contractions, Muscular
Muscle Cell Contraction
Muscle contraction, function (observable entity)
Muscle contraction, function
Muscle Contractions
muscle contraction
muscle motor activity
Muscular Contractions
Muscular Contraction
obsolete muscle motor activity
skeletal muscle contraction

External Source Codes: 
NCI Thesaurus Code C30085 (see NCI Thesaurus info)

Other Properties: Property Definitions
Name Value Source
ACTIVE 1 SNOMEDCT_US
AN do not use for HEART or MYOCARDIUM ( = MYOCARDIAL CONTRACTION) or UTERUS ( = UTERINE CONTRACTION) MSH
AQL DE ES GE IM PH RE MSH
CASE_SIGNIFICANCE_ID 900000000000448009 SNOMEDCT_US
Contributing_Source NICHD NCI
CTV3ID XU5P4 SNOMEDCT_US
DC 1 MSH
DEFINITION_STATUS_ID 900000000000074008 SNOMEDCT_US
Design_Note This concept is part of the Pediatric Adverse Events Terminology; there is no concept in MedDRA to which it can be mapped. NCI
DID 1976-0559 CSP
DX 19650101 MSH
EFFECTIVE_TIME 20020131 SNOMEDCT_US
FX D009126 MSH
FX D018763 MSH
FX D053580 MSH
GO_COMMENT This term was made obsolete because it includes anatomy information. GO
GO_NAMESPACE biological_process GO
GO_NAMESPACE molecular_function GO
GO_SUBSET goslim_pir GO
GXR Reactome:REACT_100109 "Smooth Muscle Contraction, Canis familiaris" GO
GXR Reactome:REACT_102067 "Smooth Muscle Contraction, Taeniopygia guttata" GO
GXR Reactome:REACT_20558 "Smooth Muscle Contraction, Homo sapiens" GO
GXR Reactome:REACT_29015 "Smooth Muscle Contraction, Danio rerio" GO
GXR Reactome:REACT_77478 "Smooth Muscle Contraction, Xenopus tropicalis" GO
GXR Reactome:REACT_81255 "Smooth Muscle Contraction, Mus musculus" GO
GXR Reactome:REACT_83607 "Smooth Muscle Contraction, Bos taurus" GO
GXR Reactome:REACT_85440 "Smooth Muscle Contraction, Gallus gallus" GO
GXR Reactome:REACT_87764 "Smooth Muscle Contraction, Sus scrofa" GO
GXR Reactome:REACT_88232 "Smooth Muscle Contraction, Rattus norvegicus" GO
GXR Reactome:REACT_92442 "Smooth Muscle Contraction, Dictyostelium discoideum" GO
GXR Wikipedia:Muscle_contraction GO
HN 65(64) MSH
MDA 19990101 MSH
MMR 20160623 MSH
MN G11.427.494 MSH
NICHD_Hierarchy_Term Muscle Contraction NCI
PM 65 MSH
SUBSET_MEMBER 900000000000497000~MAPTARGET~XU5P4 SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
TERMUI T027274 MSH
TERMUI T428809 MSH
TH NLM (1964) MSH
TH NLM (2002) MSH
TYPE_ID 900000000000003001 SNOMEDCT_US
TYPE_ID 900000000000013009 SNOMEDCT_US

Additional Concept Data:  (none)

URL to Bookmark: https://ncim-stage.nci.nih.gov/ncimbrowser/ConceptReport.jsp?dictionary=NCI Metathesaurus&code=C0026820

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