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methylene chloride (CUI C0025748) Suggest changes to this concept
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Terms & Properties

Concept Unique Identifier (CUI): C0025748

NCI Thesaurus Code: C44400  (see NCI Thesaurus info)

Semantic Type: Organic Chemical

Semantic Type: Hazardous or Poisonous Substance

Semantic Type: Pharmacologic Substance

NCIt Definition: A clear, colorless, nonflammable, volatile liquid chlorinated hydrocarbon with a sweet, pleasant smell and emits highly toxic fumes of phosgene when heated to decomposition. Methylene chloride is primarily used as a solvent in paint removers, but is also used in aerosol formulations, as a solvent in the manufacture of pharmaceuticals, as a degreasing agent, in electronics manufacturing and as an ethane foam blowing agent. Inhalation exposure to this substance irritates the nose and throat and affects the central nervous system. Methylene chloride is a possible mutagen and is reasonably anticipated to be a human carcinogen. (NCI05)

CSP Definition: chlorinated hydrocarbon that has been used as an inhalation anesthetic and acts as a narcotic in high concentrations; its primary use is as a solvent in manufacturing and food technology.

MSH Definition: A chlorinated hydrocarbon that has been used as an inhalation anesthetic and acts as a narcotic in high concentrations. Its primary use is as a solvent in manufacturing and food technology.

Synonyms & Abbreviations: (see Synonym Details)
Bichloride, Methylene
Chloride, Methylene
DCM
Dichloride, Methylene
Dichloromethane
Methane Dichloride
Methane, dichloro-
methylene bichloride
Methylene chloride (substance)
Methylene Chloride [Chemical/Ingredient]
methylene chloride
Methylene Dichloride
NCI-C50102

External Source Codes: 
NCI Thesaurus Code C44400 (see NCI Thesaurus info)
CAS Registry Number 75-09-2 (see NLM ChemIDplus info)
FDA UNII Code 588X2YUY0A
NSC Code 406122 (see NCI DTP info)

Other Properties: Property Definitions
Name Value Source
ACTIVE 1 SNOMEDCT_US
AN do not confuse with METHYL CHLORIDE MSH
AQL AA AD AE AG AI AN BL CF CH CL CS CT EC HI IM IP ME PD PK PO RE SD ST TO TU UR MSH
CASE_SIGNIFICANCE_ID 900000000000448009 SNOMEDCT_US
CHEBI_ID CHEBI:15767 NCI
Chemical_Formula CH2Cl2 NCI
Contributing_Source FDA NCI
CTV3ID X809x SNOMEDCT_US
DC 1 MSH
DEFINITION_STATUS_ID 900000000000074008 SNOMEDCT_US
DID 1371-7578 CSP
DX 19910101 MSH
EFFECTIVE_TIME 20020131 SNOMEDCT_US
FDA_UNII_CODE 588X2YUY0A NDFRT
HN 91(75); was see under HYDROCARBONS, CHLORINATED 1975-90 MSH
LEVEL Ingredient NDFRT
MDA 19741119 MSH
MESH_DEFINITION A chlorinated hydrocarbon that has been used as an inhalation anesthetic and acts as a narcotic in high concentrations. Its primary use is as a solvent in manufacturing and food technology. NDFRT
MESH_DUI D008752 NDFRT
MESH_NAME Methylene Chloride NDFRT
MESH_UI M0013630 NDFRT
MMR 20130708 MSH
MN D02.455.526.439.642 MSH
NDFRT_KIND DRUG_KIND NDFRT
NDFRT_KIND INGREDIENT_KIND NDFRT
NUI N0000007453 NDFRT
NUI N0000184195 NDFRT
PM 91; was see under HYDROCARBONS, CHLORINATED 1975-90 MSH
RN 588X2YUY0A MSH
RR 75-09-2 (Methylene Chloride) MSH
RXAUI 2072328 RXNORM
RXAUI 3146628 RXNORM
RXAUI 3198213 RXNORM
RXAUI 3198437 RXNORM
RXAUI 3198442 RXNORM
RXAUI 3198443 RXNORM
RXAUI 3198444 RXNORM
RXAUI 3631992 RXNORM
RXAUI 4234660 RXNORM
RXAUI 4238854 RXNORM
RXAUI 4254013 RXNORM
RXAUI 4254014 RXNORM
RXAUI 4661827 RXNORM
RXCUI 1311537 RXNORM
SPL_SET_ID 076af3a1-bbf6-407c-90c2-51a61eace283 MTHSPL
SPL_SET_ID 08c310fb-d0d6-4396-9982-55c348809433 MTHSPL
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SPL_SET_ID ee02f890-c4ed-467e-a597-011ef1dd93f9 MTHSPL
SPL_SET_ID eea16726-4802-415a-83a0-61cfad1ec405 MTHSPL
SPL_SET_ID f12f81e5-634d-480c-b607-53ec5cbad03f MTHSPL
SPL_SET_ID f7036088-40c5-444a-80d4-cead603d2f2e MTHSPL
SPL_SET_ID f839bbe5-aa04-48af-ad0c-391dd229a376 MTHSPL
SPL_SET_ID f9a15b63-f48e-4802-bd4d-53fdb65ca6a2 MTHSPL
SPL_SET_ID fb5eaae0-38c9-48a3-a389-827bc3b55c19 MTHSPL
SPL_SET_ID fd05c8b8-5d1c-4e94-952a-077f664a9575 MTHSPL
SPL_SET_ID fe3adc2c-8d27-4d32-b6b6-15d0f1fdb07b MTHSPL
SUBSET_MEMBER 900000000000497000~MAPTARGET~X809x SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
TERMUI T026084 MSH
TERMUI T026085 MSH
TERMUI T026086 MSH
TERMUI T026087 MSH
TH FDA SRS (2014) MSH
TH NLM (1975) MSH
TH UNK (19XX) MSH
TYPE_ID 900000000000003001 SNOMEDCT_US
TYPE_ID 900000000000013009 SNOMEDCT_US
VANDF_RECORD 50.416^3371^Active/Master NDFRT
VUID 4020721 NDFRT

Additional Concept Data:  (none)

URL to Bookmark: https://ncim-stage.nci.nih.gov/ncimbrowser/ConceptReport.jsp?dictionary=NCI Metathesaurus&code=C0025748

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