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Methaqualone (CUI C0025627) Suggest changes to this concept
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Terms & Properties

Concept Unique Identifier (CUI): C0025627

NCI Thesaurus Code: C640  (see NCI Thesaurus info)

Semantic Type: Pharmacologic Substance

Semantic Type: Organic Chemical

NCIt Definition: A sedative, hypnotic agent that was used for insomnia, but was taken off of the market, in the U.S., in 1983 due to its high risk of abuse.(NCI)

MSH Definition: A quinazoline derivative with hypnotic and sedative properties. It has been withdrawn from the market in many countries because of problems with abuse. (From Martindale, The Extra Pharmacopoeia, 30th ed, p604)

Synonyms & Abbreviations: (see Synonym Details)
2-Methyl-3-(2-methylphenyl)-4(3H)-quinazolinone
2-Methyl-3-o-tolyl-4(3H)-quinazolinone
3,4-Dihydro-2-methyl-4-oxo-3-o-tolylquinazoline
4(3H)-Quinazolinone, 2-methyl-3-(2-methylphenyl)-
Cateudyl
Citexal
Dormigoa
Dormogen
Dormutil
Dorsedin
Fadormir
Holodorm
Hyminal
Hypcol
Hyptor
Ipnofil
MAOA
Melsomin
Mequin
Methaqualone (substance)
Methaqualone [Chemical/Ingredient]
methaqualone
Metolquizolone
Mollinox
Motolon
MTQ
Nobedorm
Noctilene
Normi-Nox
Omnyl
Optinoxan
Ortonal
Parest
Parminal
Quaalude
QZ 2
QZ-2
RIC 272
RIC-272
Rorer 148
Roulone
Rouqualone
Sindesvel
Somberol
Somnafac
Somnomed
Sonal
Soverin
Torinal
TR 495
TR-495
Tuazolone

External Source Codes: 
NCI Thesaurus Code C640 (see NCI Thesaurus info)
CAS Registry Number 72-44-6 (see NLM ChemIDplus info)
FDA UNII Code 7ZKH8MQW6T
NSC Code 126877 (see NCI DTP info)

Other Properties: Property Definitions
Name Value Source
ACTIVE 1 SNOMEDCT_US
AQL AA AD AE AG AI AN BL CF CH CL CS CT EC HI IM IP ME PD PK PO RE SD ST TO TU UR MSH
CASE_SIGNIFICANCE_ID 900000000000448009 SNOMEDCT_US
Chemical_Formula C16H14N2O NCI
Contributing_Source FDA NCI
CTV3ID XUJcn SNOMEDCT_US
DC 1 MSH
DEFINITION_STATUS_ID 900000000000074008 SNOMEDCT_US
DX 19680101 MSH
EFFECTIVE_TIME 20020131 SNOMEDCT_US
FDA_UNII_CODE 7ZKH8MQW6T NDFRT
HN 68 MSH
LEVEL Ingredient NDFRT
LT TRD MSH
MDA 19990101 MSH
MESH_DEFINITION A quinazoline derivative with hypnotic and sedative properties. It has been withdrawn from the market in many countries because of problems with abuse. (From Martindale, The Extra Pharmacopoeia, 30th ed, p604) NDFRT
MESH_DUI D008702 NDFRT
MESH_NAME Methaqualone NDFRT
MESH_UI M0013560 NDFRT
MMR 20160531 MSH
MN D03.633.100.786.830.666 MSH
NDFRT_KIND DRUG_KIND NDFRT
NDFRT_KIND INGREDIENT_KIND NDFRT
NUI N0000166928 NDFRT
NUI N0000176151 NDFRT
PA D006993 MSH
PM 68 MSH
RN 0 MSH
RN 7ZKH8MQW6T MSH
RR 72-44-6 (Methaqualone) MSH
RR RJQ4G25ZRH MSH
RXAUI 222038 RXNORM
RXAUI 2844532 RXNORM
RXAUI 3093473 RXNORM
RXAUI 3193133 RXNORM
RXAUI 3193134 RXNORM
RXAUI 3198240 RXNORM
RXAUI 3198241 RXNORM
RXAUI 3198665 RXNORM
RXAUI 3210848 RXNORM
RXCUI 6823 RXNORM
SOS First synthesized in 1951, it was once believed not to have the adverse side effects associated with barbiturates; recent reports stress that it has no advantages over other sedatives (Falco 1975). Trade names include Hymnal, Mandrax, Parest, Quaalude, Somnafac, and Sopor. Classification: sedative/hypnotics. Slang names: ludes, mandrakes, sopors, quads. See also appendix B. (RIS 27:216--2 entries) AOD
SOS Nonbarbiturate sedative-hypnotic that produces sleep for about 6 to 8 hours, originally marketed as an alternative to barbiturates. When taken in large doses for purposes other than sleep inducement, it produces muscular relaxation, feelings of contentment, and total passivity, a state somewhat resembling drunkenness. AOD
SUBSET_MEMBER 900000000000497000~MAPTARGET~XUJcn SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
TERMUI T025890 MSH
TERMUI T025891 MSH
TERMUI T025892 MSH
TERMUI T025893 MSH
TH BAN (19XX) MSH
TH FDA SRS (2014) MSH
TH INN (19XX) MSH
TH NLM (1995) MSH
TH UNK (19XX) MSH
TH USAN (1962) MSH
TYPE_ID 900000000000003001 SNOMEDCT_US
TYPE_ID 900000000000013009 SNOMEDCT_US
VANDF_RECORD 50.416^4512^Active/Master NDFRT
VUID 4027428 NDFRT

Additional Concept Data:  (none)

URL to Bookmark: https://ncim-stage.nci.nih.gov/ncimbrowser/ConceptReport.jsp?dictionary=NCI Metathesaurus&code=C0025627

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