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Methamphetamine (CUI C0025611) Suggest changes to this concept
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Terms & Properties

Concept Unique Identifier (CUI): C0025611

NCI Thesaurus Code: C61840  (see NCI Thesaurus info)

Semantic Type: Pharmacologic Substance

Semantic Type: Hazardous or Poisonous Substance

Semantic Type: Organic Chemical

NCIt Definition: An amphetamine with central nervous system (CNS) stimulating activity. Methamphetamine acts by both facilitating the release of catecholamines, particularly noradrenaline, dopamine and serotonin, from nerve terminals in the brain and by inhibiting their uptake. This leads to an increase in synaptic concentration of these neurotransmitters and results in increased stimulation of postsynaptic receptors.

MEDLINEPLUS Definition: 

Methamphetamine - meth for short - is a very addictive stimulant drug. It is a powder that can be made into a pill or a shiny rock (called a crystal). The powder can be eaten or snorted up the nose. It can also be mixed with liquid and injected into your body with a needle. Crystal meth is smoked in a small glass pipe.

Meth at first causes a rush of good feelings, but then users feel edgy, overly excited, angry, or afraid. Meth use can quickly lead to addiction. It causes medical problems including

  • Making your body temperature so high that you pass out
  • Severe itching
  • "Meth mouth" - broken teeth and dry mouth
  • Thinking and emotional problems

NIH: National Institute on Drug Abuse

CSP Definition: sympathomimetic amine closely related chemically to both amphetamine and ephedrine, with actions similar to those of amphetamine; abuse may lead to dependence.

MSH Definition: A central nervous system stimulant and sympathomimetic with actions and uses similar to DEXTROAMPHETAMINE. The smokable form is a drug of abuse and is referred to as crank, crystal, crystal meth, ice, and speed.

Synonyms & Abbreviations: (see Synonym Details)
(+)-(S)-N-alpha-Dimethylphenethylamine
(+)-(S)-N-α-dimethylphenethylamine
(AlphaS)-N,alpha-dimethylbenzeneethanamine
(S)-N,alpha-Dimethylbenzeneethanamine
(S)-N,α-dimethylbenzeneethanamine
(αS)-N,α-dimethylbenzeneethanamine
Benzeneethanamine, N,alpha-dimethyl-, (S)-
Chalk
crank
Crystal
d-1-phenyl-2-methylaminopropane
d-deoxyephedrine
d-desoxyephedrine
d-N-methylamphetamine
d-phenylisopropylmethylamine
deoxyephedrine
Desoxyephedrine
Glass
ice
Metamfetamine
Metamfetaminum
Metanfetamina
Methamphetamine (substance)
Methamphetamine [Chemical/Ingredient]
methamphetamine
Methamphetaminum
Methyl-beta-phenylisopropylamine
methyl-β-phenylisopropylamine
Methylamphetamine
Meth
Métamfétamine
N Methylamphetamine
N-Methylamphetamine
Product containing metamfetamine (medicinal product)
Product containing metamfetamine
Product containing methamphetamine
Speed
Tina

External Source Codes: 
NCI Thesaurus Code C61840 (see NCI Thesaurus info)
CAS Registry Number 537-46-2 (see NLM ChemIDplus info)
FDA UNII Code 44RAL3456C

Other Properties: Property Definitions
Name Value Source
ACTIVE 1 SNOMEDCT_US
AN a CNS stimulant; smokable crystal methamphetamine, called "ice" by drug abusers, goes here MSH
ANSWER_CODE 3 LNC
AQL AA AD AE AG AI AN BL CF CH CL CS CT EC HI IM IP ME PD PK PO RE SD ST TO TU UR MSH
CASE_SIGNIFICANCE_ID 900000000000448009 SNOMEDCT_US
CHARACTERISTIC_TYPE_ID 900000000000011006 SNOMEDCT_US
CHEBI_ID CHEBI:6809 NCI
Chemical_Formula C10H15N NCI
Contributing_Source FDA NCI
CTV3ID XUMf8 SNOMEDCT_US
CTV3ID XUWxO SNOMEDCT_US
DATE_CREATED 11/10/1999 MEDLINEPLUS
DC 1 MSH
DEFINITION_STATUS_ID 900000000000074008 SNOMEDCT_US
DID 2268-6486 CSP
DX 19660101 MSH
EFFECTIVE_TIME 20020131 SNOMEDCT_US
EFFECTIVE_TIME 20030131 SNOMEDCT_US
EXTERNALLY_DEFINED N LNC
FDA_UNII_CODE 44RAL3456C DRUGBANK
FDA_UNII_CODE 44RAL3456C NDFRT
LEVEL Example Part D Eligible Drugs USPMG
LEVEL Ingredient NDFRT
MDA 19990101 MSH
MESH_DEFINITION A central nervous system stimulant and sympathomimetic with actions and uses similar to DEXTROAMPHETAMINE. The smokable form is a drug of abuse and is referred to as crank, crystal, crystal meth, ice, and speed. NDFRT
MESH_DUI D008694 NDFRT
MESH_NAME Methamphetamine NDFRT
MESH_UI M0013551 NDFRT
MMR 20160701 MSH
MN D02.092.471.683.152.619 MSH
MODIFIER_ID 900000000000451002 SNOMEDCT_US
MP_HEALTH_TOPIC_URL https://www.nlm.nih.gov/medlineplus/methamphetamine.html MEDLINEPLUS
MP_OTHER_LANGUAGE_URL Spanish https://www.nlm.nih.gov/medlineplus/spanish/methamphetamine.html MEDLINEPLUS
MP_PRIMARY_INSTITUTE_URL National Institute on Drug Abuse http://www.nida.nih.gov/ MEDLINEPLUS
NDFRT_KIND DRUG_KIND NDFRT
NDFRT_KIND INGREDIENT_KIND NDFRT
NUI N0000006656 NDFRT
NUI N0000147910 NDFRT
PA D000697 MSH
PA D013566 MSH
PA D015259 MSH
PA D018663 MSH
PA D018759 MSH
PA D018765 MSH
RN 44RAL3456C MSH
RR 537-46-2 (Methamphetamine) MSH
RR 997F43Z9CV MSH
RXAUI 2072278 RXNORM
RXAUI 221784 RXNORM
RXAUI 3117103 RXNORM
RXAUI 3145673 RXNORM
RXAUI 3146072 RXNORM
RXAUI 3193089 RXNORM
RXAUI 3193090 RXNORM
RXAUI 3198121 RXNORM
RXAUI 3198193 RXNORM
RXAUI 3198196 RXNORM
RXAUI 3198394 RXNORM
RXAUI 3201522 RXNORM
RXAUI 6395618 RXNORM
RXAUI 6395662 RXNORM
RXCUI 6816 RXNORM
SOS A central nervous system stimulant similar to amphetamine sulfate (Benzedrine) but more potent. The favored drug among habitual amphetamine users, who frequently take it by intravenous injection, which produces an almost instantaneous onset of the drug's effects and which many users compare to a sexual orgasm. Manufactured as Methedrine and Desoxyn. AOD
SPL_SET_ID 15e150c7-1347-40fb-9f58-c390521bc6f9 MTHSPL
SPL_SET_ID f03a68d5-ed00-8a2d-af68-28be909ea85f MTHSPL
SPL_SET_ID f31f580f-1f08-4a0f-b078-0b9e3308f712 MTHSPL
SUBSET_MEMBER 900000000000497000~MAPTARGET~XUMf8 SNOMEDCT_US
SUBSET_MEMBER 900000000000497000~MAPTARGET~XUWxO SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
TERMUI T025859 MSH
TERMUI T025860 MSH
TERMUI T025861 MSH
TERMUI T025862 MSH
TERMUI T025863 MSH
TERMUI T025864 MSH
TH FDA SRS (2014) MSH
TH INN (19XX) MSH
TH NLM (1966) MSH
TH UNK (19XX) MSH
TYPE_ID 900000000000003001 SNOMEDCT_US
TYPE_ID 900000000000013009 SNOMEDCT_US
VANDF_RECORD 50.416^2444^Active/Master NDFRT
VANDF_RECORD 50.6^1021^Active/Master NDFRT
VUID 4019821 NDFRT

Additional Concept Data:  (none)

URL to Bookmark: https://ncim-stage.nci.nih.gov/ncimbrowser/ConceptReport.jsp?dictionary=NCI Metathesaurus&code=C0025611

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