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Mesothelioma (CUI C0025500) Suggest changes to this concept
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Terms & Properties

Concept Unique Identifier (CUI): C0025500

NCI Thesaurus Code: C3234  (see NCI Thesaurus info)

Semantic Type: Neoplastic Process

NCIt Definition: A usually malignant and aggressive neoplasm of the mesothelium which is often associated with exposure to asbestos.

RADLEX Definition: A tumor derived from mesothelial tissue (peritoneum, pleura, pericardium). It appears as broad sheets of cells, with some regions containing spindle-shaped, sarcoma-like cells and other regions showing adenomatous patterns. Pleural mesotheliomas have been linked to exposure to asbestos. (Dorland, 27th ed) [MeSH]

MEDLINEPLUS Definition: 

The tissue that lines your lungs, stomach, heart, and other organs is called mesothelium. Mesothelioma is a tumor of that tissue. It usually starts in the lungs, but can also start in the abdomen or other organs. It can be benign (not cancer) or malignant (cancer.)

Malignant mesothelioma is a rare but serious type of cancer. Most people who get it have worked on jobs where they inhaled asbestos particles. After being exposed to asbestos, it usually takes a long time for the disease to form.

Symptoms include

  • Trouble breathing
  • Pain under the rib cage
  • Pain, swelling, or lumps in the abdomen
  • Weight loss for no known reason

Sometimes it is hard to tell the difference between malignant mesothelioma and lung cancer. Your doctor uses imaging tests and a biopsy to make the diagnosis. Malignant mesothelioma is often found when it is advanced. This makes it harder to treat. Treatment may include surgery, radiation, and/or chemotherapy.

NIH: National Cancer Institute

NCI-GLOSS Definition: A benign (noncancerous) or malignant (cancerous) tumor affecting the lining of the chest or abdomen. Exposure to asbestos particles in the air increases the risk of developing malignant mesothelioma.

CTEP Definition: CTEP_For_FDA: 10027410/Mesothelioma malignant NOS

CSP Definition: malignant tumor derived from mesothelial tissues of peritoneum, pleura, and pericardium.

MSH Definition: A tumor derived from mesothelial tissue (peritoneum, pleura, pericardium). It appears as broad sheets of cells, with some regions containing spindle-shaped, sarcoma-like cells and other regions showing adenomatous patterns. Pleural mesotheliomas have been linked to exposure to asbestos. (Dorland, 27th ed)

Synonyms & Abbreviations: (see Synonym Details)
Mesothelioma (C45)
Mesothelioma [Disease/Finding]
Mesothelioma, NOS
Mesothelioma, unspecified
Mesotheliomas
mesothelioma
Mesotheliom

External Source Codes: 
NCI Thesaurus Code C3234 (see NCI Thesaurus info)

Other Properties: Property Definitions
Name Value Source
AN benign or malignant; coordinate IM with precoordinated organ/neoplasm term (IM); LOCALIZED MESOTHELIOMA and FIBROUS MESOTHELIOMA see SOLITARY FIBROUS TUMOR, PLEURAL is also available MSH
AQL BL BS CF CH CI CL CN CO DG DH DI DT EC EH EM EN EP ET GE HI IM ME MI MO NU PA PC PP PS PX RH RT SC SE SU TH UL UR VE VI MSH
CASE_SIGNIFICANCE_ID 900000000000448009 SNOMEDCT_US
Contributing_Source CTEP NCI
Contributing_Source CTRP NCI
DATE_CREATED 11/30/2004 MEDLINEPLUS
DC 1 MSH
DID 2005-3609 CSP
DX 19660101 MSH
IAN DEFAULT ICD10
INCLUSION_TERM morphology code M905 with behaviour code /3 ICD10
MDA 19990101 MSH
MESH_DEFINITION A tumor derived from mesothelial tissue (peritoneum, pleura, pericardium). It appears as broad sheets of cells, with some regions containing spindle-shaped, sarcoma-like cells and other regions showing adenomatous patterns. Pleural mesotheliomas have been linked to exposure to asbestos. (Dorland, 27th ed) NDFRT
MESH_DUI D008654 NDFRT
MESH_NAME Mesothelioma NDFRT
MESH_UI M0013485 NDFRT
MMR 20070709 MSH
MN C04.557.470.035.510 MSH
MN C04.557.470.660.510 MSH
MP_HEALTH_TOPIC_URL https://www.nlm.nih.gov/medlineplus/mesothelioma.html MEDLINEPLUS
MP_OTHER_LANGUAGE_URL Spanish https://www.nlm.nih.gov/medlineplus/spanish/mesothelioma.html MEDLINEPLUS
MP_PRIMARY_INSTITUTE_URL National Cancer Institute http://www.nci.nih.gov/ MEDLINEPLUS
NDFRT_KIND DISEASE_KIND NDFRT
Neoplastic_Status Undetermined NCI
NUI N0000002003 NDFRT
ORDER_NO 01705 ICD10CM
ORDER_NO 01710 ICD10CM
PRIMARY_PATH 10027406$10027414$10027412$10029104$Mesothelioma$Mesotheliomas malignant and unspecified$Mesotheliomas$Neoplasms benign, malignant and unspecified (incl cysts and polyps) MDR
PRIMARY_SOC 10029104 MDR
PT_IN_VERSION 10.0 MDR
PT_IN_VERSION 10.1 MDR
PT_IN_VERSION 11.0 MDR
PT_IN_VERSION 11.1 MDR
PT_IN_VERSION 12.0 MDR
PT_IN_VERSION 12.1 MDR
PT_IN_VERSION 13.0 MDR
PT_IN_VERSION 13.1 MDR
PT_IN_VERSION 14.0 MDR
PT_IN_VERSION 14.1 MDR
PT_IN_VERSION 15.0 MDR
PT_IN_VERSION 15.1 MDR
PT_IN_VERSION 16.0 MDR
PT_IN_VERSION 16.1 MDR
PT_IN_VERSION 17.0 MDR
PT_IN_VERSION 17.1 MDR
PT_IN_VERSION 18.0 MDR
PT_IN_VERSION 18.1 MDR
PT_IN_VERSION 19.0 MDR
PT_IN_VERSION 19.1 MDR
PT_IN_VERSION 20.0 MDR
PT_IN_VERSION 20.1 MDR
PT_IN_VERSION 8.0 MDR
PT_IN_VERSION 8.1 MDR
PT_IN_VERSION 9.0 MDR
PT_IN_VERSION 9.1 MDR
RXAUI 3197887 RXNORM
RXAUI 3197888 RXNORM
RXCUI 1024487 RXNORM
SMQ_TERM_ADDVERSION 10.0 MDR
SMQ_TERM_CAT A MDR
SMQ_TERM_LEVEL 4 MDR
SMQ_TERM_LMVERSION 20.0 MDR
SMQ_TERM_SCOPE 2 MDR
SMQ_TERM_STATUS A MDR
SMQ_TERM_WEIGHT 0 MDR
SNOMED_CID 62064005 NDFRT
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
TERM_LEVEL Synonym ICDO
TERMUI T025739 MSH
TH NLM (1966) MSH
TYPE_ID 900000000000013009 SNOMEDCT_US

Additional Concept Data:  (none)

URL to Bookmark: https://ncim-stage.nci.nih.gov/ncimbrowser/ConceptReport.jsp?dictionary=NCI Metathesaurus&code=C0025500

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