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Maprotiline (CUI C0024778) Suggest changes to this concept
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Terms & Properties

Concept Unique Identifier (CUI): C0024778

NCI Thesaurus Code: C61824  (see NCI Thesaurus info)

Semantic Type: Pharmacologic Substance

Semantic Type: Organic Chemical

MSH Definition: A bridged-ring tetracyclic antidepressant that is both mechanistically and functionally similar to the tricyclic antidepressants, including side effects associated with its use.

Synonyms & Abbreviations: (see Synonym Details)
9,10-Ethanoanthracene-9(10H)-propanamine, N-methyl-
Dibencycladine
Maprotilina
Maprotiline (substance)
Maprotiline [Chemical/Ingredient]
maprotiline
Maprotilinum
Maprotilin
Maprotylina
N-Methyl-9,10-ethanoanthracene-9(10H)-propylamine
Product containing maprotiline (medicinal product)
Product containing maprotiline

External Source Codes: 
NCI Thesaurus Code C61824 (see NCI Thesaurus info)
CAS Registry Number 10262-69-8 (see NLM ChemIDplus info)
FDA UNII Code 2U1W68TROF

Other Properties: Property Definitions
Name Value Source
ACTIVE 1 SNOMEDCT_US
AQL AA AD AE AG AI AN BL CF CH CL CS CT EC HI IM IP ME PD PK PO RE SD ST TO TU UR MSH
CASE_SIGNIFICANCE_ID 900000000000448009 SNOMEDCT_US
CHARACTERISTIC_TYPE_ID 900000000000011006 SNOMEDCT_US
Chemical_Formula C20H23N NCI
Contributing_Source FDA NCI
CTV3ID x01Au SNOMEDCT_US
CTV3ID XUWsC SNOMEDCT_US
DC 1 MSH
DEFINITION_STATUS_ID 900000000000074008 SNOMEDCT_US
DX 19910101 MSH
EFFECTIVE_TIME 20020131 SNOMEDCT_US
EFFECTIVE_TIME 20030131 SNOMEDCT_US
FDA_UNII_CODE 2U1W68TROF DRUGBANK
FDA_UNII_CODE 2U1W68TROF NDFRT
HN 91(75); was see under ANTHRACENES 1975-90 MSH
LEVEL Example Part D Eligible Drugs USPMG
LEVEL Ingredient NDFRT
MDA 19741119 MSH
MESH_DEFINITION A bridged-ring tetracyclic antidepressant that is both mechanistically and functionally similar to the tricyclic antidepressants, including side effects associated with its use. NDFRT
MESH_DUI D008376 NDFRT
MESH_NAME Maprotiline NDFRT
MESH_UI M0013021 NDFRT
MMR 20160701 MSH
MN D02.455.426.559.847.117.600 MSH
MN D04.615.117.600 MSH
MODIFIER_ID 900000000000451002 SNOMEDCT_US
NDFRT_KIND DRUG_KIND NDFRT
NDFRT_KIND INGREDIENT_KIND NDFRT
NUI N0000007296 NDFRT
NUI N0000147895 NDFRT
PA D018687 MSH
PA D018759 MSH
PM 91; was see under ANTHRACENES 1975-90 MSH
RN 2U1W68TROF MSH
RR 10262-69-8 (Maprotiline) MSH
RR 10347-81-6 (HCl) MSH
RR 22P65W41V0 MSH
RR 58902-67-3 (mesylate) MSH
RR 7C8J54PVFI MSH
RXAUI 1847767 RXNORM
RXAUI 2072179 RXNORM
RXAUI 3094655 RXNORM
RXAUI 3146546 RXNORM
RXAUI 3191708 RXNORM
RXAUI 3191709 RXNORM
RXAUI 3196665 RXNORM
RXAUI 3196666 RXNORM
RXAUI 3196669 RXNORM
RXAUI 3201511 RXNORM
RXAUI 6395599 RXNORM
RXCUI 6646 RXNORM
SID APRD00747 DRUGBANK
SPL_SET_ID c3ca69e6-1ea0-4c2c-abcb-7264b2e79a87 MTHSPL
SUBSET_MEMBER 900000000000497000~MAPTARGET~x01Au SNOMEDCT_US
SUBSET_MEMBER 900000000000497000~MAPTARGET~XUWsC SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
TERMUI T024910 MSH
TERMUI T024911 MSH
TERMUI T024912 MSH
TERMUI T024913 MSH
TH BAN (19XX) MSH
TH FDA SRS (2014) MSH
TH INN (19XX) MSH
TH NLM (1995) MSH
TH UNK (19XX) MSH
TH USAN (1971) MSH
TYPE_ID 900000000000003001 SNOMEDCT_US
TYPE_ID 900000000000013009 SNOMEDCT_US
VANDF_RECORD 50.416^2429^Active/Master NDFRT
VANDF_RECORD 50.6^1127^Active/Master NDFRT
VUID 4019806 NDFRT

Additional Concept Data:  (none)

URL to Bookmark: https://ncim-stage.nci.nih.gov/ncimbrowser/ConceptReport.jsp?dictionary=NCI Metathesaurus&code=C0024778

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