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Malathion (CUI C0024547) Suggest changes to this concept
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Terms & Properties

Concept Unique Identifier (CUI): C0024547

NCI Thesaurus Code: C47593  (see NCI Thesaurus info)

Semantic Type: Organic Chemical

Semantic Type: Pharmacologic Substance

Semantic Type: Hazardous or Poisonous Substance

NCIt Definition: A synthetic phosphorous compound and cholinesterase inhibitor that is strictly used as a topical pediculicide. Malathion exerts its action on the nervous system of the lice by irreversibly inhibiting the activity of cholinesterase, thereby allowing acetylcholine to accumulate at cholinergic synapses and enhancing cholinergic receptor stimulation. This eventually leads to the head lice's death.

MSH Definition: A wide spectrum aliphatic organophosphate insecticide widely used for both domestic and commercial agricultural purposes.

Synonyms & Abbreviations: (see Synonym Details)
[(Dimethoxyphosphinothioyl)thio]butanedioic acid diethyl ester
Butanedioic acid, ((dimethoxyphosphinothioyl)thio)-, diethyl ester
Butanedioic Acid,((dimethoxyphosphinothioyl)thio)-, Diethyl Ester
Carbafos
Carbofos
Carbophos
Diethyl (dimethoxyphosphinothioylthio)succinate
Karbofos
Malathion (substance)
Malathion [Chemical/Ingredient]
malathion
Maldison
Mercaptothion
O,O-Dimethyl S-(1,2-bis(ethoxycarbonyl)ethyl)
O,O-Dimethyl S-(1,2-dicarbethoxyethyl) dithiophosphate
O,O-Dimethyl S-(1,2-dicarbethoxyethyl)phosphorodithioate
O,O-Dimethyl S-1,2-di(ethoxycarbamyl)ethyl
O,O-Dimethyldithiophosphate diethylmercaptosuccinate
Ovide
Product containing malathion (medicinal product)
Product containing malathion
Succinic Acid, mercapto-, Diethyl Ester, S-ester with O,O-Dimethylphosphorodithioate

External Source Codes: 
NCI Thesaurus Code C47593 (see NCI Thesaurus info)
CAS Registry Number 121-75-5 (see NLM ChemIDplus info)
FDA UNII Code U5N7SU872W
NSC Code 6524 (see NCI DTP info)

Other Properties: Property Definitions
Name Value Source
ACTIVE 1 SNOMEDCT_US
AN for use to kill or control insects, use no qualifiers on the insecticide or the insect; appropriate qualifiers may be used when other aspects of the insecticide are discussed such as the effect on a physiologic process or behavioral aspect of the insect; for poisoning, coordinate with ORGANOPHOSPHATE POISONING MSH
AQL AA AD AE AG AI AN BL CF CH CL CS CT EC HI IM IP ME PD PK RE SD ST TO TU UR MSH
CASE_SIGNIFICANCE_ID 900000000000448009 SNOMEDCT_US
CHARACTERISTIC_TYPE_ID 900000000000011006 SNOMEDCT_US
CHEBI_ID CHEBI:6651 NCI
Chemical_Formula C10H19O6PS2 NCI
Contributing_Source FDA NCI
CTV3ID mg5.. SNOMEDCT_US
CTV3ID XM0lX SNOMEDCT_US
DC 1 MSH
DEFINITION_STATUS_ID 900000000000074008 SNOMEDCT_US
DID 2253-8399 CSP
DX 19720101 MSH
EFFECTIVE_TIME 20020131 SNOMEDCT_US
FDA_UNII_CODE U5N7SU872W DRUGBANK
FDA_UNII_CODE U5N7SU872W NDFRT
HN 72 MSH
LEVEL Example Part D Eligible Drugs USPMG
LEVEL Ingredient NDFRT
LT TRD MTH
MDA 19990101 MSH
MESH_DEFINITION A wide spectrum aliphatic organophosphate insecticide widely used for both domestic and commercial agricultural purposes. NDFRT
MESH_DUI D008294 NDFRT
MESH_NAME Malathion NDFRT
MESH_UI M0012917 NDFRT
MMR 20130708 MSH
MN D02.705.400.625.500 MSH
MN D02.705.539.345.500 MSH
MN D02.886.300.692.500 MSH
MODIFIER_ID 900000000000451002 SNOMEDCT_US
NDFRT_KIND DRUG_KIND NDFRT
NDFRT_KIND INGREDIENT_KIND NDFRT
NUI N0000006399 NDFRT
NUI N0000146761 NDFRT
PA D002800 MSH
PA D007306 MSH
PM 72 MSH
RN U5N7SU872W MSH
RR 121-75-5 (Malathion) MSH
RXAUI 1312786 RXNORM
RXAUI 2072162 RXNORM
RXAUI 214888 RXNORM
RXAUI 2982494 RXNORM
RXAUI 3119422 RXNORM
RXAUI 3129857 RXNORM
RXAUI 3129963 RXNORM
RXAUI 3130114 RXNORM
RXAUI 3184286 RXNORM
RXAUI 3191468 RXNORM
RXAUI 3191469 RXNORM
RXAUI 3196263 RXNORM
RXAUI 3196264 RXNORM
RXAUI 4619980 RXNORM
RXCUI 261602 RXNORM
RXCUI 6606 RXNORM
RXN_BN_CARDINALITY single RXNORM
SID APRD01081 DRUGBANK
SPL_SET_ID 2024030e-b00d-4fcc-b51d-45dc86933749 MTHSPL
SPL_SET_ID 6937e1ff-2dc0-47b7-902a-1c9d237e3233 MTHSPL
SPL_SET_ID 945f46fa-4b79-49fd-a890-477f251e2164 MTHSPL
SPL_SET_ID a0b1444b-f51b-44fd-8f23-2fff49b64bc0 MTHSPL
SPL_SET_ID d792c1cb-ec9b-4942-8096-101d01293cea MTHSPL
SPL_SET_ID e9ea6c59-0a3d-4ce0-96ab-f8e9c38ce9db MTHSPL
SUBSET_MEMBER 900000000000497000~MAPTARGET~mg5.. SNOMEDCT_US
SUBSET_MEMBER 900000000000497000~MAPTARGET~XM0lX SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
TERMUI T024737 MSH
TERMUI T024739 MSH
TERMUI T024742 MSH
TERMUI T024743 MSH
TERMUI T024744 MSH
TH BAN (19XX) MSH
TH FDA SRS (2014) MSH
TH NLM (1990) MSH
TH UNK (19XX) MSH
TH USP (19XX) MSH
TYPE_ID 900000000000003001 SNOMEDCT_US
TYPE_ID 900000000000013009 SNOMEDCT_US
VANDF_RECORD 50.416^1033^Active/Master NDFRT
VANDF_RECORD 50.6^737^Active/Master NDFRT
VUID 4018435 NDFRT

Additional Concept Data:  (none)

URL to Bookmark: https://ncim-stage.nci.nih.gov/ncimbrowser/ConceptReport.jsp?dictionary=NCI Metathesaurus&code=C0024547

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