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Magnesium Hydroxide (CUI C0024476) Suggest changes to this concept
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Terms & Properties

Concept Unique Identifier (CUI): C0024476

NCI Thesaurus Code: C29262  (see NCI Thesaurus info)

Semantic Type: Pharmacologic Substance

Semantic Type: Inorganic Chemical

NCIt Definition: A solution of magnesium hydroxide with antacid and laxative properties. Milk of magnesium exerts its antacid activity in low doses such that all hydroxide ions that enter the stomach are used to neutralize stomach acid. This agent exerts its laxative effect in higher doses so that hydroxide ions are able to move from the stomach to the intestines where they attract and retain water, thereby increasing intestinal movement (peristalsis) and inducing the urge to defecate.

PDQ Definition: A solution of magnesium hydroxide with antacid and laxative properties. Milk of magnesium exerts its antacid activity in low doses such that all hydroxide ions that enter the stomach are used to neutralize stomach acid. This agent exerts its laxative effect in higher doses so that hydroxide ions are able to move from the stomach to the intestines where they attract and retain water, thereby increasing intestinal movement (peristalsis) and inducing the urge to defecate. Check for active clinical trials using this agent. (NCI Thesaurus)

MSH Definition: An inorganic compound that occurs in nature as the mineral brucite. It acts as an antacid with cathartic effects.

Synonyms & Abbreviations: (see Synonym Details)
Hydrate, Magnesium
Hydroxide, Magnesium
Magnesium dihydroxide
Magnesium Hydrate
Magnesium hydroxide (Mg(OH)2)
Magnesium hydroxide (product)
Magnesium hydroxide (substance)
Magnesium Hydroxide [Chemical/Ingredient]
Magnesium Hydroxide
MILK OF MAGNESIA [VA Product]
Milk of magnesia

External Source Codes: 
NCI Thesaurus Code C29262 (see NCI Thesaurus info)
CAS Registry Number 1309-42-8 (see NLM ChemIDplus info)
FDA UNII Code NBZ3QY004S
PDQ Closed Trial Search ID 537610
PDQ Open Trial Search ID 537610 (check for NCI PDQ open clinical trial info)

Other Properties: Property Definitions
Name Value Source
ACTIVE 1 SNOMEDCT_US
AQL AD AE AG AI AN BL CF CH CL CS CT EC HI IM IP ME PD PK PO RE SD ST TO TU UR MSH
CASE_SIGNIFICANCE_ID 900000000000020002 SNOMEDCT_US
CHARACTERISTIC_TYPE_ID 900000000000011006 SNOMEDCT_US
CHEBI_ID CHEBI:6637 NCI
Chemical_Formula Mg.2HO NCI
Contributing_Source FDA NCI
CTV3ID x007O SNOMEDCT_US
CTV3ID XUWuj SNOMEDCT_US
DATE_FIRST_PUBLISHED 2007-02-21 PDQ
DATE_LAST_MODIFIED 2007-02-21 PDQ
DC 1 MSH
DCSA 0 NDFRT
DCSA UNSCHEDULED VANDF
DDF SUSP,ORAL VANDF
DEFINITION_STATUS_ID 900000000000074008 SNOMEDCT_US
DX 19910101 MSH
EFFECTIVE_TIME 20020131 SNOMEDCT_US
EFFECTIVE_TIME 20030131 SNOMEDCT_US
FDA_UNII_CODE NBZ3QY004S DRUGBANK
FDA_UNII_CODE NBZ3QY004S NDFRT
HN 91(77); was see under MAGNESIUM 1977-90 MSH
LEVEL Ingredient NDFRT
LEVEL VA Product NDFRT
LT TRD PDQ
MDA 19760413 MSH
MESH_DEFINITION An inorganic compound that occurs in nature as the mineral brucite. It acts as an antacid with cathartic effects. NDFRT
MESH_DUI D008276 NDFRT
MESH_NAME Magnesium Hydroxide NDFRT
MESH_UI M0012887 NDFRT
MMR 20150623 MSH
MN D01.045.250.575 MSH
MN D01.248.497.158.459.388 MSH
MN D01.524.485 MSH
MODIFIER_ID 900000000000451002 SNOMEDCT_US
NCI_THESAURUS_CODE C29262 PDQ
NDC 000003055341 VANDF
NDC 000003055361 VANDF
NDC 000054356761 VANDF
NDC 000054357354 VANDF
NDC 000067002712 VANDF
NDC 000067002812 VANDF
NDC 000067002912 VANDF
NDC 000084066834 VANDF
NDC 000113033240 VANDF
NDC 000113039640 VANDF
NDC 000113094940 VANDF
NDC 000122082466 VANDF
NDC 000182083339 VANDF
NDC 000182083340 VANDF
NDC 000182083341 VANDF
NDC 000182608439 VANDF
NDC 000182608440 VANDF
NDC 000223627901 VANDF
NDC 000223627902 VANDF
NDC 000223627912 VANDF
NDC 000247071101 VANDF
NDC 000247071166 VANDF
NDC 000295119316 VANDF
NDC 000363033235 VANDF
NDC 000363033240 VANDF
NDC 000363094935 VANDF
NDC 000363094940 VANDF
NDC 000363191112 VANDF
NDC 000363192112 VANDF
NDC 000363192126 VANDF
NDC 000363193112 VANDF
NDC 000363193126 VANDF
NDC 000364732178 VANDF
NDC 000395167016 VANDF
NDC 000395167028 VANDF
NDC 000395167116 VANDF
NDC 000436062716 VANDF
NDC 000436062728 VANDF
NDC 000436062732 VANDF
NDC 000436062742 VANDF
NDC 000436062816 VANDF
NDC 000436062842 VANDF
NDC 000463901528 VANDF
NDC 000527076127 VANDF
NDC 000527076128 VANDF
NDC 000527076129 VANDF
NDC 000536247083 VANDF
NDC 000536247085 VANDF
NDC 000574001810 VANDF
NDC 000574001816 VANDF
NDC 000574001832 VANDF
NDC 000603078757 VANDF
NDC 000603078857 VANDF
NDC 000615073816 VANDF
NDC 000677081832 VANDF
NDC 000714004116 VANDF
NDC 000714004128 VANDF
NDC 000781653516 VANDF
NDC 000839539067 VANDF
NDC 000839539069 VANDF
NDC 000839539070 VANDF
NDC 000869415610 VANDF
NDC 000879020116 VANDF
NDC 000879020128 VANDF
NDC 000879020132 VANDF
NDC 000904078814 VANDF
NDC 000904078816 VANDF
NDC 000904078828 VANDF
NDC 000904078914 VANDF
NDC 004850227200 VANDF
NDC 004850229600 VANDF
NDC 010939002101 VANDF
NDC 010939009901 VANDF
NDC 010939038633 VANDF
NDC 010939038733 VANDF
NDC 010939038833 VANDF
NDC 010939038933 VANDF
NDC 010939057944 VANDF
NDC 010939058044 VANDF
NDC 010939058644 VANDF
NDC 010939068711 VANDF
NDC 010939068811 VANDF
NDC 010939078222 VANDF
NDC 010939078922 VANDF
NDC 010939089733 VANDF
NDC 011822039940 VANDF
NDC 011822308100 VANDF
NDC 011822332980 VANDF
NDC 011822505530 VANDF
NDC 011917004046 VANDF
NDC 011917004047 VANDF
NDC 011917004048 VANDF
NDC 011917004049 VANDF
NDC 011917006227 VANDF
NDC 011917007640 VANDF
NDC 011917011505 VANDF
NDC 011917015118 VANDF
NDC 011917015592 VANDF
NDC 011917015593 VANDF
NDC 011917015595 VANDF
NDC 011917015603 VANDF
NDC 012333924801 VANDF
NDC 012333924901 VANDF
NDC 012810039640 VANDF
NDC 012843035301 VANDF
NDC 012843035302 VANDF
NDC 012843035303 VANDF
NDC 012843036304 VANDF
NDC 012843036305 VANDF
NDC 012843036306 VANDF
NDC 012843039322 VANDF
NDC 012843039324 VANDF
NDC 012843039325 VANDF
NDC 015127083373 VANDF
NDC 015127083573 VANDF
NDC 021140070385 VANDF
NDC 021140070682 VANDF
NDC 021140070683 VANDF
NDC 021140070693 VANDF
NDC 021695090316 VANDF
NDC 024385033240 VANDF
NDC 024385039640 VANDF
NDC 024385060840 VANDF
NDC 024385067016 VANDF
NDC 030142033240 VANDF
NDC 030142039640 VANDF
NDC 035515095563 VANDF
NDC 036800004873 VANDF
NDC 036800011890 VANDF
NDC 036800094940 VANDF
NDC 037205045940 VANDF
NDC 037205083340 VANDF
NDC 037205083440 VANDF
NDC 037937002339 VANDF
NDC 037937009939 VANDF
NDC 040986001408 VANDF
NDC 040986001409 VANDF
NDC 041163010112 VANDF
NDC 041163025588 VANDF
NDC 041163033235 VANDF
NDC 041163033240 VANDF
NDC 041163039640 VANDF
NDC 041415023673 VANDF
NDC 042254022416 VANDF
NDC 042507039640 VANDF
NDC 049348030539 VANDF
NDC 049348030739 VANDF
NDC 049348031344 VANDF
NDC 049348068039 VANDF
NDC 049348068739 VANDF
NDC 049348068744 VANDF
NDC 049348068839 VANDF
NDC 049348068844 VANDF
NDC 049614033240 VANDF
NDC 049614033840 VANDF
NDC 049614033940 VANDF
NDC 049781004012 VANDF
NDC 049999076916 VANDF
NDC 050428214916 VANDF
NDC 050428233005 VANDF
NDC 050428305623 VANDF
NDC 050428308240 VANDF
NDC 050428699075 VANDF
NDC 051079038238 VANDF
NDC 051432062620 VANDF
NDC 051432062621 VANDF
NDC 052297007240 VANDF
NDC 052297012540 VANDF
NDC 052297033240 VANDF
NDC 052297039640 VANDF
NDC 052735050829 VANDF
NDC 053807012501 VANDF
NDC 053807012502 VANDF
NDC 053807012503 VANDF
NDC 053807012512 VANDF
NDC 053807012516 VANDF
NDC 053807012528 VANDF
NDC 054868234500 VANDF
NDC 054868234501 VANDF
NDC 054868234502 VANDF
NDC 056039191102 VANDF
NDC 056039191106 VANDF
NDC 056039192106 VANDF
NDC 056039193102 VANDF
NDC 056062094940 VANDF
NDC 057866312001 VANDF
NDC 057896064916 VANDF
NDC 058016112901 VANDF
NDC 058948033240 VANDF
NDC 058948039640 VANDF
NDC 060258096016 VANDF
NDC 062107002411 VANDF
NDC 062559000503 VANDF
NDC 062559191101 VANDF
NDC 063868031012 VANDF
NDC 063868078757 VANDF
NDC 063868078857 VANDF
NDC 068016001408 VANDF
NDC 068016001409 VANDF
NDC 070030014700 VANDF
NDC 075450029758 VANDF
NDC 081131069993 VANDF
NDC 087701040023 VANDF
NDC 087701060152 VANDF
NDC 087701060153 VANDF
NDC 091899001829 VANDF
NDC 091899033840 VANDF
NDC 096295011279 VANDF
NDC 096295012501 VANDF
NDF_TRANSMIT_TO_CMOP YES VANDF
NDF_UNITS MG/5ML NDFRT
NDFRT_KIND DRUG_KIND NDFRT
NDFRT_KIND INGREDIENT_KIND NDFRT
NF_NAME MAGNESIUM HYDROXIDE SUSP,ORAL NDFRT
NF_NAME MAGNESIUM HYDROXIDE SUSP,ORAL VANDF
NFI YES VANDF
NUI N0000006344 NDFRT
NUI N0000146067 NDFRT
NUI N0000161723 NDFRT
ORIG_STY Drug/agent PDQ
PA D000863 MSH
PM 91; was see under MAGNESIUM 1977-90 MSH
RN NBZ3QY004S MSH
RR 108173-30-4 (Mg(OH)4) MSH
RR 1309-42-8 (Magnesium Hydroxide) MSH
RXAUI 1001269 RXNORM
RXAUI 1001270 RXNORM
RXAUI 2072149 RXNORM
RXAUI 213921 RXNORM
RXAUI 2638023 RXNORM
RXAUI 2844779 RXNORM
RXAUI 3051381 RXNORM
RXAUI 3191333 RXNORM
RXAUI 3191334 RXNORM
RXAUI 3194435 RXNORM
RXAUI 3194436 RXNORM
RXAUI 3194440 RXNORM
RXAUI 3196188 RXNORM
RXAUI 3196189 RXNORM
RXAUI 3196190 RXNORM
RXAUI 3196203 RXNORM
RXAUI 3503557 RXNORM
RXAUI 5470069 RXNORM
RXCUI 152039 RXNORM
RXCUI 6581 RXNORM
RXN_ACTIVATED 01/28/2010 RXNORM
RXN_OBSOLETED 03/27/2013 RXNORM
RXN_OBSOLETED 04/30/2009 RXNORM
SNGL_OR_MULT_SRC_PRD Multisource VANDF
SNOMEDID C-14817 SNOMEDCT_US
SNOMEDID C-84232 SNOMEDCT_US
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SPL_SET_ID fa0b70c8-50e0-4184-9795-c17739c46630 MTHSPL
SPL_SET_ID fa4ac98b-eb2b-4027-9548-3f3d9c9d6534 MTHSPL
SPL_SET_ID fb8d8f82-a296-4d29-b0c6-882b6fea17d9 MTHSPL
SPL_SET_ID fc3c5c56-772f-44f8-b42f-88909ad68a5e MTHSPL
SPL_SET_ID fc4dfaf2-9ba5-4371-a703-085d4a5bfd75 MTHSPL
SPL_SET_ID fd1e2fff-50b6-4cf0-b820-376c02cc6dce MTHSPL
SPL_SET_ID fdb97db3-503e-41d4-a67b-11b46eeb177f MTHSPL
SPL_SET_ID fdf66de5-7d61-4908-ac96-7625c575dbe8 MTHSPL
SPL_SET_ID ff859c0c-083c-4b6c-bc24-59a8896a63ce MTHSPL
STRENGTH 350-425 NDFRT
SUBSET_MEMBER 900000000000497000~MAPTARGET~x007O SNOMEDCT_US
SUBSET_MEMBER 900000000000497000~MAPTARGET~XUWuj SNOMEDCT_US
SUBSET_MEMBER 900000000000498005~MAPTARGET~C-14817 SNOMEDCT_US
SUBSET_MEMBER 900000000000498005~MAPTARGET~C-84232 SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
TERMUI T024682 MSH
TERMUI T024683 MSH
TH FDA SRS (2014) MSH
TH NLM (1994) MSH
TH USP (19XX) MSH
TYPE_ID 900000000000003001 SNOMEDCT_US
TYPE_ID 900000000000013009 SNOMEDCT_US
VA_CLASS_NAME [GA108] MAGNESIUM CONTAINING ANTACIDS VANDF
VA_DISPENSE_UNIT ML VANDF
VA_GENERIC_NAME MAGNESIUM HYDROXIDE VANDF
VAC GA108 VANDF
VANDF_RECORD 50.416^288^Active/Master NDFRT
VANDF_RECORD 50.68^13593^Active/Master NDFRT
VANDF_RECORD 50.6^2206^Active/Master NDFRT
VMO M0473 VANDF
VUID 4013958 NDFRT
VUID 4017693 NDFRT

Additional Concept Data:  (none)

URL to Bookmark: https://ncim-stage.nci.nih.gov/ncimbrowser/ConceptReport.jsp?dictionary=NCI Metathesaurus&code=C0024476

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