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Lymphoma (CUI C0024299) Suggest changes to this concept
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Terms & Properties

Concept Unique Identifier (CUI): C0024299

NCI Thesaurus Code: C3208  (see NCI Thesaurus info)

Semantic Type: Neoplastic Process

NCIt Definition: A malignant (clonal) proliferation of B- lymphocytes or T- lymphocytes which involves the lymph nodes, bone marrow and/or extranodal sites. This category includes Non-Hodgkin lymphomas and Hodgkin lymphomas.

RADLEX Definition: A general term for various neoplastic diseases of the lymphoid tissue. [MeSH]

PDQ Definition: A malignant (clonal) proliferation of B- lymphocytes or T- lymphocytes which involves the lymph nodes, bone marrow and/or extranodal sites. This category includes Non-Hodgkin lymphomas and Hodgkin lymphomas. Check for active clinical trials using this agent. (NCI Thesaurus)

HPO Definition: A cancer originating in lymphocytes and presenting as a solid tumor of lymhpoid cells. [HPO:probinson]

MEDLINEPLUS Definition: 

Lymphoma is a cancer of a part of the immune system called the lymph system. There are many types of lymphoma. One type is Hodgkin disease. The rest are called non-Hodgkin lymphomas.

Non-Hodgkin lymphomas begin when a type of white blood cell, called a T cell or B cell, becomes abnormal. The cell divides again and again, making more and more abnormal cells. These abnormal cells can spread to almost any other part of the body. Most of the time, doctors don't know why a person gets non-Hodgkin lymphoma. You are at increased risk if you have a weakened immune system or have certain types of infections.

Non-Hodgkin lymphoma can cause many symptoms, such as

  • Swollen, painless lymph nodes in the neck, armpits or groin
  • Unexplained weight loss
  • Fever
  • Soaking night sweats
  • Coughing, trouble breathing or chest pain
  • Weakness and tiredness that don't go away
  • Pain, swelling or a feeling of fullness in the abdomen

Your doctor will diagnose lymphoma with a physical exam, blood tests, a chest x-ray, and a biopsy. Treatments include chemotherapy, radiation therapy, targeted therapy, biological therapy, or therapy to remove proteins from the blood. Targeted therapy uses substances that attack cancer cells without harming normal cells. Biologic therapy boosts your body's own ability to fight cancer. If you don't have symptoms, you may not need treatment right away. This is called watchful waiting.

NIH: National Cancer Institute

NICHD Definition: A malignant neoplasm of the lymphatic system that is comprised of abnormal lymphocytes.

CDISC Definition: A malignant neoplasm composed of lymphocytes of B- or T/NK-cell phenotype.

NCI-GLOSS Definition: Cancer that begins in cells of the immune system. There are two basic categories of lymphomas. One kind is Hodgkin lymphoma, which is marked by the presence of a type of cell called the Reed-Sternberg cell. The other category is non-Hodgkin lymphomas, which includes a large, diverse group of cancers of immune system cells. Non-Hodgkin lymphomas can be further divided into cancers that have an indolent (slow-growing) course and those that have an aggressive (fast-growing) course. These subtypes behave and respond to treatment differently. Both Hodgkin and non-Hodgkin lymphomas can occur in children and adults, and prognosis and treatment depend on the stage and the type of cancer.

CTEP Definition: CTEP_For_FDA: 10025316/Lymphoma NOS

CSP Definition: malignant (clonal) proliferation of B- or T- lymphocytes which involves the lymph nodes, bone marrow and/or extranodal sites; general term for various neoplastic diseases of the lymphoid tissue.

MSH Definition: A general term for various neoplastic diseases of the lymphoid tissue.

Synonyms & Abbreviations: (see Synonym Details)
Germinoblastic Sarcomas
Germinoblastic Sarcoma
Germinoblastomas
Germinoblastoma
Hodgkin and non-Hodgkin lymphomas
Lymphoma (clinical)
Lymphoma (Hodgkin and Non-Hodgkin)
Lymphoma (Hodgkin's and Non-Hodgkin's)
Lymphoma [Disease/Finding]
LYMPHOMA MALIGNANT
Lymphoma NOS
LYMPHOMA, MALIGNANT
Lymphoma, NOS
Lymphomas, Malignant
Lymphomas
Lymphomatous
lymphoma
Lymphom
Malignant lymphoma (clinical)
Malignant lymphoma (disorder)
Malignant lymphoma NOS
Malignant lymphoma, no ICD-O subtype
Malignant lymphoma, no International Classification of Diseases for Oncology subtype (morphologic abnormality)
Malignant lymphoma, no International Classification of Diseases for Oncology subtype
Malignant lymphoma, NOS
Malignant Lymphomas
Malignant Lymphoma
Reticulolymphosarcoma, diffuse
Reticulolymphosarcomas
Reticulolymphosarcoma
Sarcoma, Germinoblastic
Sarcomas, Germinoblastic

External Source Codes: 
NCI Thesaurus Code C3208 (see NCI Thesaurus info)

Other Properties: Property Definitions
Name Value Source
ACTIVE 1 SNOMEDCT_US
AN GEN only or unspecified: prefer specific; do not confuse X ref LYMPHOMA, MALIGNANT with LYMPHOGRANULOMA, MALIGNANT see HODGKIN DISEASE; for lymphoma with AIDS, use LYMPHOMA, AIDS-RELATED MSH
ANSWER_CODE 5 LNC
AQL BL CF CH CI CL CN CO DG DH DI DT EC EH EM EN EP ET GE HI IM ME MI MO NU PA PC PP PS PX RH RT SU TH UL UR VE VI MSH
CASE_SIGNIFICANCE_ID 900000000000020002 SNOMEDCT_US
CHARACTERISTIC_TYPE_ID 900000000000011006 SNOMEDCT_US
CITE Playbook RADLEX
COMMENT lymphosarcoma is obsolete and should not be used RADLEX
Contributing_Source CDISC NCI
Contributing_Source CTEP NCI
Contributing_Source CTRP NCI
Contributing_Source FDA NCI
Contributing_Source MedDRA NCI
Contributing_Source NICHD NCI
CTV3ID Xa99k SNOMEDCT_US
CTV3ID XU9h0 SNOMEDCT_US
DATE_CREATED 02/26/1999 MEDLINEPLUS
DATE_LAST_MODIFIED 2011-06-02 PDQ
DC 1 MSH
DEFINITION_STATUS_ID 900000000000073002 SNOMEDCT_US
DEFINITION_STATUS_ID 900000000000074008 SNOMEDCT_US
DID 2004-6589 CSP
DX 19660101 MSH
EFFECTIVE_TIME 20020131 SNOMEDCT_US
EFFECTIVE_TIME 20050131 SNOMEDCT_US
EXTERNALLY_DEFINED N LNC
ICD-O-3_Code 9590/3 NCI
ICD-O-3_CODE 9590/3 SNOMEDCT_US
MDA 19990101 MSH
MESH_DEFINITION A general term for various neoplastic diseases of the lymphoid tissue. NDFRT
MESH_DUI D008223 NDFRT
MESH_NAME Lymphoma NDFRT
MESH_UI M0012817 NDFRT
MMR 20030709 MSH
MN C04.557.386 MSH
MN C15.604.515.569 MSH
MN C20.683.515.761 MSH
MODIFIER_ID 900000000000451002 SNOMEDCT_US
MP_HEALTH_TOPIC_URL https://www.nlm.nih.gov/medlineplus/lymphoma.html MEDLINEPLUS
MP_OTHER_LANGUAGE_URL Chinese - Traditional https://www.nlm.nih.gov/medlineplus/languages/lymphoma.html#Chinese - Traditional MEDLINEPLUS
MP_OTHER_LANGUAGE_URL Spanish https://www.nlm.nih.gov/medlineplus/spanish/lymphoma.html MEDLINEPLUS
MP_PRIMARY_INSTITUTE_URL National Cancer Institute http://www.nci.nih.gov/ MEDLINEPLUS
NCI_THESAURUS_CODE C3208 PDQ
NDFRT_KIND DISEASE_KIND NDFRT
Neoplastic_Status Malignant NCI
NICHD_Hierarchy_Term Lymphoma NCI
NUI N0000001905 NDFRT
ORIG_STY Neoplasm diagnosis PDQ
PID 450 PDQ
PRIMARY_PATH 10025310$10025324$10025323$10029104$Lymphoma$Lymphomas unspecified NEC$Lymphomas NEC$Neoplasms benign, malignant and unspecified (incl cysts and polyps) MDR
PRIMARY_SOC 10029104 MDR
PT_IN_VERSION 10.0 MDR
PT_IN_VERSION 10.1 MDR
PT_IN_VERSION 11.0 MDR
PT_IN_VERSION 11.1 MDR
PT_IN_VERSION 12.0 MDR
PT_IN_VERSION 12.1 MDR
PT_IN_VERSION 13.0 MDR
PT_IN_VERSION 13.1 MDR
PT_IN_VERSION 14.0 MDR
PT_IN_VERSION 14.1 MDR
PT_IN_VERSION 15.0 MDR
PT_IN_VERSION 15.1 MDR
PT_IN_VERSION 16.0 MDR
PT_IN_VERSION 16.1 MDR
PT_IN_VERSION 17.0 MDR
PT_IN_VERSION 17.1 MDR
PT_IN_VERSION 18.0 MDR
PT_IN_VERSION 18.1 MDR
PT_IN_VERSION 19.0 MDR
PT_IN_VERSION 19.1 MDR
PT_IN_VERSION 8.0 MDR
PT_IN_VERSION 8.1 MDR
PT_IN_VERSION 9.0 MDR
PT_IN_VERSION 9.1 MDR
RXAUI 3165312 RXNORM
RXAUI 3190703 RXNORM
RXAUI 3190705 RXNORM
RXAUI 3190808 RXNORM
RXAUI 3231821 RXNORM
RXAUI 3236569 RXNORM
RXCUI 1024259 RXNORM
SMQ_TERM_ADDVERSION 10.0 MDR
SMQ_TERM_ADDVERSION 16.0 MDR
SMQ_TERM_CAT A MDR
SMQ_TERM_LEVEL 4 MDR
SMQ_TERM_LEVEL 5 MDR
SMQ_TERM_LMVERSION 16.0 MDR
SMQ_TERM_LMVERSION 20.0 MDR
SMQ_TERM_SCOPE 2 MDR
SMQ_TERM_STATUS A MDR
SMQ_TERM_WEIGHT 0 MDR
SNOMED_CID 118600007 NDFRT
SNOMEDID DC-F0000 SNOMEDCT_US
SNOMEDID M-95903 SNOMEDCT_US
SUBSET_MEMBER 446608001~MAPTARGET~9590/3 SNOMEDCT_US
SUBSET_MEMBER 447562003~CORRELATIONID~447561005 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPADVICE~ALWAYS C85.9 | POSSIBLE REQUIREMENT FOR MORPHOLOGY CODE SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPCATEGORYID~447637006 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPGROUP~1 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPPRIORITY~1 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPRULE~TRUE SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPTARGET~C85.9 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~CORRELATIONID~447561005 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~ALWAYS C85.90 | DESCENDANTS NOT EXHAUSTIVELY MAPPED SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPCATEGORYID~447637006 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPGROUP~1 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~1 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~TRUE SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~C85.90 SNOMEDCT_US
SUBSET_MEMBER 900000000000497000~MAPTARGET~Xa99k SNOMEDCT_US
SUBSET_MEMBER 900000000000497000~MAPTARGET~XU9h0 SNOMEDCT_US
SUBSET_MEMBER 900000000000498005~MAPTARGET~DC-F0000 SNOMEDCT_US
SUBSET_MEMBER 900000000000498005~MAPTARGET~M-95903 SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
TERM_LEVEL 2 ICDO
TERM_LEVEL 4 ICDO
TERM_LEVEL Synonym ICDO
TERMUI T024486 MSH
TERMUI T024487 MSH
TERMUI T024488 MSH
TERMUI T024489 MSH
TERMUI T024490 MSH
TH NLM (1966) MSH
TH NLM (1993) MSH
TH UNK (19XX) MSH
TYPE_ID 900000000000003001 SNOMEDCT_US
TYPE_ID 900000000000013009 SNOMEDCT_US

Additional Concept Data:  (none)

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