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Lyme Disease (CUI C0024198) Suggest changes to this concept
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Terms & Properties

Concept Unique Identifier (CUI): C0024198

NCI Thesaurus Code: C45161  (see NCI Thesaurus info)

Semantic Type: Disease or Syndrome

NCIt Definition: An infectious disease caused by the spirochete Borrelia burgdorferi. Early manifestations of infection may include fever, headache, fatigue, depression, and a characteristic skin rash called erythema migrans. Left untreated, late manifestations involving the joints, heart, and nervous system can occur.

MEDLINEPLUS Definition: 

Lyme disease is a bacterial infection you get from the bite of an infected tick. The first symptom is usually a rash, which may look like a bull's eye. As the infection spreads, you may have

  • A fever
  • A headache
  • Muscle and joint aches
  • A stiff neck
  • Fatigue

Lyme disease can be hard to diagnose because you may not have noticed a tick bite. Also, many of its symptoms are like those of the flu and other diseases. In the early stages, your health care provider will look at your symptoms and medical history, to figure out whether you have Lyme disease. Lab tests may help at this stage, but may not always give a clear answer. In the later stages of the disease, a different lab test can confirm whether you have it.

Antibiotics can cure most cases of Lyme disease. The sooner treatment begins, the quicker and more complete the recovery.

After treatment, some patients may still have muscle or joint aches and nervous system symptoms. This is called post-Lyme disease syndrome (PLDS). Long-term antibiotics have not been shown to help with PLDS. However, there are ways to help with the symptoms of PLDS, and most patients do get better with time.

NIH: National Institute of Allergy and Infectious Diseases

NICHD Definition: An infectious disease that is caused by the spirochete Borrelia burgdorferi.

CSP Definition: recurrent multisystemic infectious disease caused by a spirochete, Borrelia burgdorferi, which is transmitted chiefly by Ixodes ticks; it is a disease with early and late cutaneous manifestations plus involvement of the nervous system, heart, eye, and joints in variable combinations.

MSH Definition: An infectious disease caused by a spirochete, BORRELIA BURGDORFERI, which is transmitted chiefly by Ixodes dammini (see IXODES) and pacificus ticks in the United States and Ixodes ricinis (see IXODES) in Europe. It is a disease with early and late cutaneous manifestations plus involvement of the nervous system, heart, eye, and joints in variable combinations. The disease was formerly known as Lyme arthritis and first discovered at Old Lyme, Connecticut.

Synonyms & Abbreviations: (see Synonym Details)
Borrelia burgdorferi infection
Borrelia
Borreliosis, Lyme
Disease, Lyme
Infection due to Borrelia burgdorferi sensu lato
Lyme borreliosis
Lyme disease (disorder)
Lyme Disease [Disease/Finding]
LYME DISEASE, EARLY/MID
Lyme disease, unspecified
Lyme Disease
LYME DIS
Lyme's disease
Lymes disease
Steere's disease

External Source Codes: 
NCI Thesaurus Code C45161 (see NCI Thesaurus info)

Other Properties: Property Definitions
Name Value Source
ACTIVE 1 SNOMEDCT_US
AN coord IM with specific Borrelia (IM) MSH
ANSWER_CODE 11080 LNC
ANSWER_CODE_SYSTEM NNDSS LNC
AQL BL CF CI CL CN CO DG DH DI DT EC EH EM EN EP ET GE HI IM ME MI MO NU PA PC PP PS PX RH RT SU TH TM UR VE VI MSH
CASE_SIGNIFICANCE_ID 900000000000017005 SNOMEDCT_US
CASE_SIGNIFICANCE_ID 900000000000020002 SNOMEDCT_US
CHARACTERISTIC_TYPE_ID 900000000000011006 SNOMEDCT_US
Contributing_Source NICHD NCI
CTV3ID A8710 SNOMEDCT_US
DATE_CREATED 10/22/1998 MEDLINEPLUS
DC 1 MSH
DEFINITION_STATUS_ID 900000000000074008 SNOMEDCT_US
DID 0368-3340 CSP
DX 19850101 MSH
EFFECTIVE_TIME 20160131 SNOMEDCT_US
EXTERNALLY_DEFINED N LNC
HN 85; was LYME ARTHRITIS see ARTHRITIS, INFECTIOUS l979-84 MSH
IAN DEFAULT ICD10
ICE Erythema chronicum migrans ICD9CM
INCLUSION_TERM Erythema chronicum migrans due to Borrelia burgdorferi ICD10
MDA 19840406 MSH
MESH_DEFINITION An infectious disease caused by a spirochete, BORRELIA BURGDORFERI, which is transmitted chiefly by Ixodes dammini (see IXODES) and pacificus ticks in the United States and Ixodes ricinis (see IXODES) in Europe. It is a disease with early and late cutaneous manifestations plus involvement of the nervous system, heart, eye, and joints in variable combinations. The disease was formerly known as Lyme arthritis and first discovered at Old Lyme, Connecticut. NDFRT
MESH_DUI D008193 NDFRT
MESH_NAME Lyme Disease NDFRT
MESH_UI M0012774 NDFRT
MMR 20010807 MSH
MN C01.252.400.155.569 MSH
MN C01.252.400.825.480 MSH
MN C01.252.847.193.569 MSH
MODIFIER_ID 900000000000451002 SNOMEDCT_US
MP_HEALTH_TOPIC_URL https://www.nlm.nih.gov/medlineplus/lymedisease.html MEDLINEPLUS
MP_OTHER_LANGUAGE_URL Spanish https://www.nlm.nih.gov/medlineplus/spanish/lymedisease.html MEDLINEPLUS
MP_PRIMARY_INSTITUTE_URL National Institute of Allergy and Infectious Diseases http://www.niaid.nih.gov/ MEDLINEPLUS
NDFRT_KIND DISEASE_KIND NDFRT
NICHD_Hierarchy_Term Lyme Disease NCI
NUI N0000001890 NDFRT
OL search ARTHRITIS, INFECTIOUS 1979-84 MSH
ORDER_NO 00548 ICD10CM
ORDER_NO 00549 ICD10CM
PM 85; was LYME ARTHRITIS see ARTHRITIS, INFECTIOUS 1979-84 MSH
PRIMARY_PATH 10025169$10006038$10004018$10021881$Lyme disease$Borrelial infections$Bacterial infectious disorders$Infections and infestations MDR
PRIMARY_SOC 10021881 MDR
PT_IN_VERSION 10.0 MDR
PT_IN_VERSION 10.1 MDR
PT_IN_VERSION 11.0 MDR
PT_IN_VERSION 11.1 MDR
PT_IN_VERSION 12.0 MDR
PT_IN_VERSION 12.1 MDR
PT_IN_VERSION 13.0 MDR
PT_IN_VERSION 13.1 MDR
PT_IN_VERSION 14.0 MDR
PT_IN_VERSION 14.1 MDR
PT_IN_VERSION 15.0 MDR
PT_IN_VERSION 15.1 MDR
PT_IN_VERSION 16.0 MDR
PT_IN_VERSION 16.1 MDR
PT_IN_VERSION 17.0 MDR
PT_IN_VERSION 17.1 MDR
PT_IN_VERSION 18.0 MDR
PT_IN_VERSION 18.1 MDR
PT_IN_VERSION 19.0 MDR
PT_IN_VERSION 19.1 MDR
PT_IN_VERSION 20.0 MDR
PT_IN_VERSION 20.1 MDR
PT_IN_VERSION 8.0 MDR
PT_IN_VERSION 8.1 MDR
PT_IN_VERSION 9.0 MDR
PT_IN_VERSION 9.1 MDR
RXAUI 3190441 RXNORM
RXAUI 3190443 RXNORM
RXAUI 3190449 RXNORM
RXCUI 1021886 RXNORM
SNOMED_CID 23502006 NDFRT
SUBSET_MEMBER 447562003~CORRELATIONID~447561005 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPADVICE~ALWAYS A69.2 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPCATEGORYID~447637006 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPGROUP~1 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPPRIORITY~1 SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPRULE~TRUE SNOMEDCT_US
SUBSET_MEMBER 447562003~MAPTARGET~A69.2 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~CORRELATIONID~447561005 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPADVICE~ALWAYS A69.20 | DESCENDANTS NOT EXHAUSTIVELY MAPPED SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPCATEGORYID~447637006 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPGROUP~1 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPPRIORITY~1 SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPRULE~TRUE SNOMEDCT_US
SUBSET_MEMBER 6011000124106~MAPTARGET~A69.20 SNOMEDCT_US
SUBSET_MEMBER 900000000000497000~MAPTARGET~A8710 SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000508004~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000548007 SNOMEDCT_US
SUBSET_MEMBER 900000000000509007~ACCEPTABILITYID~900000000000549004 SNOMEDCT_US
TERMUI T024416 MSH
TERMUI T024417 MSH
TH NLM (1985) MSH
TH NLM (1992) MSH
TYPE_ID 900000000000003001 SNOMEDCT_US
TYPE_ID 900000000000013009 SNOMEDCT_US

Additional Concept Data:  (none)

URL to Bookmark: https://ncim-stage.nci.nih.gov/ncimbrowser/ConceptReport.jsp?dictionary=NCI Metathesaurus&code=C0024198

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